Stanislav I Tomarev

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis
    Stanislav I Tomarev
    Laboratory of Molecular and Developmental Biology, National Institutes of Health, Bethesda, Maryland 20892 2730, USA
    Invest Ophthalmol Vis Sci 44:2588-96. 2003
  2. ncbi Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology
    Stanislav I Tomarev
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, 5635 Fishers Lane, Room 1124, Bethesda, MD, 20892, USA
    Mol Neurobiol 40:122-38. 2009
  3. ncbi Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth
    Naoki Nakaya
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 0606, USA
    J Biol Chem 287:37171-84. 2012
  4. ncbi Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins
    Afia Sultana
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Invest Ophthalmol Vis Sci 52:2584-92. 2011
  5. ncbi Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma
    Yu Zhou
    Section of Molecular Mechanism of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Invest Ophthalmol Vis Sci 49:1932-9. 2008
  6. ncbi Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A
    Mario Torrado
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institute of Health, Bethesda, MD 20892 0704, USA
    Invest Ophthalmol Vis Sci 45:3955-63. 2004
  7. ncbi Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway
    Naoki Nakaya
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:7900-10. 2008
  8. ncbi Mutated mouse and human myocilins have similar properties and do not block general secretory pathway
    Irina Malyukova
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
    Invest Ophthalmol Vis Sci 47:206-12. 2006
  9. ncbi Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis
    Farid Ahmed
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, MD 20814 9692, USA
    Invest Ophthalmol Vis Sci 45:3081-90. 2004
  10. ncbi Expression of myocilin mutants sensitizes cells to oxidative stress-induced apoptosis: implication for glaucoma pathogenesis
    Myung Kuk Joe
    Molecular Mechanisms of Glaucoma Section, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, 5635 Fishers Lane, Room 1124, Bethesda, MD 20892, USA
    Am J Pathol 176:2880-90. 2010

Collaborators

Detail Information

Publications20

  1. ncbi Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis
    Stanislav I Tomarev
    Laboratory of Molecular and Developmental Biology, National Institutes of Health, Bethesda, Maryland 20892 2730, USA
    Invest Ophthalmol Vis Sci 44:2588-96. 2003
    ..To characterize the gene expression pattern in the human trabecular meshwork (TM) and identify candidate genes for glaucoma by expressed sequence tag (EST) analysis as part of the NEIBank project...
  2. ncbi Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology
    Stanislav I Tomarev
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, 5635 Fishers Lane, Room 1124, Bethesda, MD, 20892, USA
    Mol Neurobiol 40:122-38. 2009
    ..In this review, we summarize recent advances in understanding the possible roles of these proteins with special emphasis on the proteins that are preferentially expressed and function in neural tissues...
  3. ncbi Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth
    Naoki Nakaya
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 0606, USA
    J Biol Chem 287:37171-84. 2012
    ..These data introduce Olfm1 as a novel NgR1 ligand that may modulate the functions of the NgR1 complex in axonal growth...
  4. ncbi Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins
    Afia Sultana
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Invest Ophthalmol Vis Sci 52:2584-92. 2011
    ..Genetic data suggest its association with glaucoma in Japanese patients. However, its functions are still elusive. In this study, the properties of mammalian OLFM2 were investigated...
  5. ncbi Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma
    Yu Zhou
    Section of Molecular Mechanism of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Invest Ophthalmol Vis Sci 49:1932-9. 2008
    ....
  6. ncbi Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A
    Mario Torrado
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institute of Health, Bethesda, MD 20892 0704, USA
    Invest Ophthalmol Vis Sci 45:3955-63. 2004
    ..To characterize properties of Pdlim2, a novel PDZ and LIM domain-containing protein...
  7. ncbi Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway
    Naoki Nakaya
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:7900-10. 2008
    ..Simultaneous overexpression of WIF-1 and Olfm1 abolished the WIF-1 effect. Physical interaction of WIF-1 and Olfm1 was demonstrated by coimmunoprecipitation experiments. We concluded that Olfm1 serves as a modulator of Wnt signaling...
  8. ncbi Mutated mouse and human myocilins have similar properties and do not block general secretory pathway
    Irina Malyukova
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
    Invest Ophthalmol Vis Sci 47:206-12. 2006
    ..The present study compared properties of wild-type and mutated mouse and human myocilin (Myoc) proteins as a prerequisite for development of a mouse model of glaucoma...
  9. ncbi Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis
    Farid Ahmed
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, MD 20814 9692, USA
    Invest Ophthalmol Vis Sci 45:3081-90. 2004
    ..To characterize gene expression pattern in the combined tissues of the rat iridocorneal angle by expressed sequence tag (EST) analysis, as part of the NEIBank project...
  10. ncbi Expression of myocilin mutants sensitizes cells to oxidative stress-induced apoptosis: implication for glaucoma pathogenesis
    Myung Kuk Joe
    Molecular Mechanisms of Glaucoma Section, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, 5635 Fishers Lane, Room 1124, Bethesda, MD 20892, USA
    Am J Pathol 176:2880-90. 2010
    ..Mutant myocilins may confer different sensitivity to oxidative stress depending on the mutation...
  11. ncbi Myocilin is a modulator of Wnt signaling
    Heung Sun Kwon
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bethesda, MD 20892 0704, USA
    Mol Cell Biol 29:2139-54. 2009
    ..Myocilin and Wnt proteins may perform redundant functions in the mammalian eye, since myocilin modulates Wnt signaling by interacting with components of this signaling pathway...
  12. ncbi Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathway
    Heung Sun Kwon
    Molecular Mechanisms of Glaucoma Section, Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bethesda, Maryland 20892 9303, USA
    J Cell Physiol 226:3392-402. 2011
    ..The modification of the migratory ability of cells by myocilin may play a role in normal functioning of the eye anterior segment and its pathology including glaucoma...
  13. ncbi A mutation in ZNF513, a putative regulator of photoreceptor development, causes autosomal-recessive retinitis pigmentosa
    Lin Li
    Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Hum Genet 87:400-9. 2010
    ..These results suggest that the ZNF513 p.C339R mutation is responsible for RP in this family and that ZNF513 plays a key role in the regulation of photoreceptor-specific genes in retinal development and photoreceptor maintenance...
  14. ncbi Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex
    Myung Kuk Joe
    Retinal Ganglion Cell Biology Section, Laboratory of Retinal Cell and Molecular Biology, NEI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 287:13216-27. 2012
    ..We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of DAPC...
  15. ncbi Optimedin induces expression of N-cadherin and stimulates aggregation of NGF-stimulated PC12 cells
    Hee Sheung Lee
    Section of Molecular Mechanisms of Glaucoma, Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bldg 7, Room 103, MSC 0704, Bethesda, MD 20892 0704, USA
    Exp Cell Res 313:98-108. 2007
    ....
  16. ncbi Rodent models of glaucoma
    Thomas V Johnson
    Molecular Mechanisms of Glaucoma Section, Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
    Brain Res Bull 81:349-58. 2010
    ....
  17. ncbi Optimedin: a novel olfactomedin-related protein that interacts with myocilin
    Mario Torrado
    Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Mol Genet 11:1291-301. 2002
    ..We suggest that optimedin may be a candidate gene for disorders involving the anterior segment of the eye and the retina...
  18. ncbi Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure
    Farid Ahmed
    Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, Maryland 20814-9692, USA
    Invest Ophthalmol Vis Sci 45:1247-58. 2004
    ....
  19. ncbi Mafs, Prox1, and Pax6 can regulate chicken betaB1-crystallin gene expression
    Wenwu Cui
    Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, USA
    J Biol Chem 279:11088-95. 2004
    ....
  20. ncbi Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma
    Douglas B Gould
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Mol Cell Biol 24:9019-25. 2004
    ..This work does not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma...