Reuben Thomas

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data
    Reuben Thomas
    Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    BMC Bioinformatics 8:228. 2007
  2. pmc Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure
    Reuben Thomas
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Genome Biol 10:R44. 2009
  3. pmc Validation and characterization of DNA microarray gene expression data distribution and associated moments
    Reuben Thomas
    Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, USA
    BMC Bioinformatics 11:576. 2010
  4. pmc Genetic and environmental pathways to complex diseases
    Julia M Gohlke
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    BMC Syst Biol 3:46. 2009
  5. doi request reprint Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice
    Scott S Auerbach
    National Toxicology Program, Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 38:923-42. 2010
  6. pmc Estimating the global public health implications of electricity and coal consumption
    Julia M Gohlke
    Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 119:821-6. 2011
  7. ncbi request reprint A model-based optimization framework for the inference on gene regulatory networks from DNA array data
    Reuben Thomas
    Department of Industrial Engineering and Management Science, Northwestern University, Evanston, IL 60208 3120, USA
    Bioinformatics 20:3221-35. 2004

Detail Information

Publications7

  1. pmc A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data
    Reuben Thomas
    Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    BMC Bioinformatics 8:228. 2007
    ..These considerations should be taken into account in the development of methods for the inference of regulatory interactions in genetic networks...
  2. pmc Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure
    Reuben Thomas
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Genome Biol 10:R44. 2009
    ..The analysis provided demonstrates the method proposed is very competitive with the current approaches and also provides biologically relevant results...
  3. pmc Validation and characterization of DNA microarray gene expression data distribution and associated moments
    Reuben Thomas
    Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, USA
    BMC Bioinformatics 11:576. 2010
    ..Several different methods have been proposed to analyze these data under different distributional assumptions on gene expression. However, the empirical validation of these assumptions is lacking...
  4. pmc Genetic and environmental pathways to complex diseases
    Julia M Gohlke
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    BMC Syst Biol 3:46. 2009
    ....
  5. doi request reprint Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice
    Scott S Auerbach
    National Toxicology Program, Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 38:923-42. 2010
    ..Our studies indicate that genetically determined baseline differences in cardiac phenotype have the potential to influence the results of cardiotoxicity studies...
  6. pmc Estimating the global public health implications of electricity and coal consumption
    Julia M Gohlke
    Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 119:821-6. 2011
    ..The growing health risks associated with greenhouse gas emissions highlight the need for new energy policies that emphasize efficiency and low-carbon energy intensity...
  7. ncbi request reprint A model-based optimization framework for the inference on gene regulatory networks from DNA array data
    Reuben Thomas
    Department of Industrial Engineering and Management Science, Northwestern University, Evanston, IL 60208 3120, USA
    Bioinformatics 20:3221-35. 2004
    ....