Marie S Thearle

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Extent and determinants of thermogenic responses to 24 hours of fasting, energy balance, and five different overfeeding diets in humans
    Marie S Thearle
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85106, USA
    J Clin Endocrinol Metab 98:2791-9. 2013
  2. pmc Childhood predictors of adult acute insulin response and insulin action
    Marie S Thearle
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 32:938-43. 2009
  3. pmc Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians
    Marie S Thearle
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes 61:250-7. 2012
  4. pmc Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Hum Genet 133:1431-41. 2014
  5. pmc Overfeeding over 24 hours does not activate brown adipose tissue in humans
    Mathias Schlögl
    MD, Obesity and Diabetes Clinical Research Section, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, 4212 North 16th Street Fifth Floor, Phoenix, AZ 85016
    J Clin Endocrinol Metab 98:E1956-60. 2013
  6. pmc Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona
    Diabetes 62:4043-51. 2013
  7. pmc Assessment of non-insulin-mediated glucose uptake: association with body fat and glycemic status
    Reiner Jumpertz
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Metabolism 59:1396-401. 2010
  8. pmc Weight maintenance from young adult weight predicts better health outcomes
    Susanne B Votruba
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, Phoenix, Arizona, USA
    Obesity (Silver Spring) 22:2361-9. 2014
  9. pmc Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Diabetologia 57:1382-90. 2014
  10. pmc Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans
    Mathias Schlögl
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA Electronic address
    Appetite 90:154-9. 2015

Detail Information

Publications15

  1. pmc Extent and determinants of thermogenic responses to 24 hours of fasting, energy balance, and five different overfeeding diets in humans
    Marie S Thearle
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85106, USA
    J Clin Endocrinol Metab 98:2791-9. 2013
    ..Individual variation in the ability to convert excess calories to heat and the effects of dietary macronutrient composition are unclear...
  2. pmc Childhood predictors of adult acute insulin response and insulin action
    Marie S Thearle
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 32:938-43. 2009
    ....
  3. pmc Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians
    Marie S Thearle
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes 61:250-7. 2012
    ..The greater rates of body mass accumulation and risk of type 2 diabetes before the age of 20 years in individuals with MC4R deficiency indicate that the effects of these mutations are more apparent during the active growth of childhood...
  4. pmc Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Hum Genet 133:1431-41. 2014
    ..2 %, p = 0.002), increased food intake (β = 676 kcal/day, p = 0.007) and decreased energy expenditure (β = -53.4 kcal/day, p = 0.054). Common and rare variation in MC4R contributes to obesity in American Indians...
  5. pmc Overfeeding over 24 hours does not activate brown adipose tissue in humans
    Mathias Schlögl
    MD, Obesity and Diabetes Clinical Research Section, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, 4212 North 16th Street Fifth Floor, Phoenix, AZ 85016
    J Clin Endocrinol Metab 98:E1956-60. 2013
    ..Human brown adipose tissue (BAT) is activated with cold exposure, but it is unknown whether overfeeding activates BAT...
  6. pmc Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona
    Diabetes 62:4043-51. 2013
    ..AFT may influence daily energy balance, is reduced in obese individuals, and predicts future weight gain in these subjects. Once central adiposity develops, a blunting of AFT may occur that then contributes to further weight gain...
  7. pmc Assessment of non-insulin-mediated glucose uptake: association with body fat and glycemic status
    Reiner Jumpertz
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Metabolism 59:1396-401. 2010
    ..Our results indicate that NIMGU is associated with adiposity. NIMGU increases with declining glucose tolerance perhaps to preserve glucose uptake during increased insulin resistance...
  8. pmc Weight maintenance from young adult weight predicts better health outcomes
    Susanne B Votruba
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, Phoenix, Arizona, USA
    Obesity (Silver Spring) 22:2361-9. 2014
    ..Defining groups of individuals within a larger population with similar patterns of weight change over time may provide insight into influences of weight stability or gain...
  9. pmc Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Diabetologia 57:1382-90. 2014
    ..Rare mutations in GCK cause MODY. We investigated whether common variation (minor allele frequency ≥0.01) in GCK is associated with metabolic traits and type 2 diabetes...
  10. pmc Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans
    Mathias Schlögl
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA Electronic address
    Appetite 90:154-9. 2015
    ..The relationship between food intake and irisin concentrations in humans is unclear...
  11. pmc Lower energy expenditure predicts long-term increases in weight and fat mass
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    J Clin Endocrinol Metab 98:E703-7. 2013
    ..The relevance of the contribution of energy expenditure (EE) and substrate oxidation to weight change has not been fully confirmed...
  12. pmc Fasting hyperglycemia predicts lower rates of weight gain by increased energy expenditure and fat oxidation rate
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section P P, M S T, C B, J K, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016 and Obesity Research Center, Endocrinology Unit P P, University Hospital of Pisa, Pisa, Italy, 56124
    J Clin Endocrinol Metab 100:1078-87. 2015
    ..One possible mechanism is via increased energy expenditure (EE)...
  13. pmc A Human Thrifty Phenotype Associated With Less Weight Loss During Caloric Restriction
    Martin Reinhardt
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, AZ
    Diabetes 64:2859-67. 2015
    ..Greater decreases in energy expenditure during caloric restriction predict less weight loss, indicating the presence of thrifty and spendthrift phenotypes in obese humans. ..
  14. pmc Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section P P, M S T, J K, S B V, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016 and Obesity Research Center P P, Endocrinology Unit, University Hospital of Pisa, Pisa, Italy 56124
    J Clin Endocrinol Metab 100:3011-20. 2015
    ..Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake...
  15. pmc Perseveration augments the effects of cognitive restraint on ad libitum food intake in adults seeking weight loss
    Alexis L Graham
    Phoenix Epidemiology and Clinical Research Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
    Appetite 82:78-84. 2014
    ..The effects of perseveration on food intake are conditional on restraint, and may contribute to extremes of dietary intake in some individuals...