Philip R Taylor

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Influence of genetic background and tissue types on global DNA methylation patterns
    Howard H Yang
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 5:e9355. 2010
  2. pmc Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china
    Gangshi Wang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland, USA
    PLoS ONE 8:e63826. 2013
  3. pmc Squamous dysplasia--the precursor lesion for esophageal squamous cell carcinoma
    Philip R Taylor
    National Cancer Institute, NIH, EPS, 6120 Executive Blvd, Rm 7006, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:540-52. 2013
  4. pmc Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma
    Wusheng Yan
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, USA
    BMC Res Notes 5:73. 2012
  5. pmc Body Mass Index, percent body fat, and regional body fat distribution in relation to leptin concentrations in healthy, non-smoking postmenopausal women in a feeding study
    Somdat Mahabir
    Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Nutr J 6:3. 2007
  6. pmc Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma
    Sumana Mukherjee
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Transl Med 8:91. 2010
  7. pmc Selection and validation of endogenous reference genes using a high throughput approach
    Ping Jin
    Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, NIH Bethesda, MD 20892, USA
    BMC Genomics 5:55. 2004
  8. pmc Family history of cancer and risk for esophageal and gastric cancer in Shanxi, China
    Ying Gao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    BMC Cancer 9:269. 2009
  9. pmc Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma
    Li yan Xue
    Department of Pathology, Cancer Institute Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
    BMC Cancer 6:296. 2006
  10. ncbi request reprint Prospective study of serum vitamin E levels and esophageal and gastric cancers
    Philip R Taylor
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 8314, USA
    J Natl Cancer Inst 95:1414-6. 2003

Collaborators

Detail Information

Publications129 found, 100 shown here

  1. pmc Influence of genetic background and tissue types on global DNA methylation patterns
    Howard H Yang
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 5:e9355. 2010
    ..Furthermore, we showed that tissue types are important contributors of DNA methylation states...
  2. pmc Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china
    Gangshi Wang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland, USA
    PLoS ONE 8:e63826. 2013
    ..To profile RNA expression in gastric cancer by anatomic subsites as an initial step in identifying molecular subtypes and providing targets for early detection and therapy...
  3. pmc Squamous dysplasia--the precursor lesion for esophageal squamous cell carcinoma
    Philip R Taylor
    National Cancer Institute, NIH, EPS, 6120 Executive Blvd, Rm 7006, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:540-52. 2013
    ..Future research on ESD and ESCC should focus on finding additional modifiable risk factors and on identifying biomarkers to incorporate into early detection strategies...
  4. pmc Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma
    Wusheng Yan
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, USA
    BMC Res Notes 5:73. 2012
    ..abstract:..
  5. pmc Body Mass Index, percent body fat, and regional body fat distribution in relation to leptin concentrations in healthy, non-smoking postmenopausal women in a feeding study
    Somdat Mahabir
    Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Nutr J 6:3. 2007
    ....
  6. pmc Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma
    Sumana Mukherjee
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Transl Med 8:91. 2010
    ..Proteases modulate cancer progression by facilitating tumor invasion and metastasis. In the current study, matrix metalloproteinases (MMPs) were studied in a search for new early detection markers for ESCC...
  7. pmc Selection and validation of endogenous reference genes using a high throughput approach
    Ping Jin
    Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, NIH Bethesda, MD 20892, USA
    BMC Genomics 5:55. 2004
    ..Whether this assumption is correct it is, however, still matter of debate. In this study, we searched for stably expressed genes in 384 cDNA array hybridization experiments encompassing different tissues and cell lines...
  8. pmc Family history of cancer and risk for esophageal and gastric cancer in Shanxi, China
    Ying Gao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    BMC Cancer 9:269. 2009
    ..Family history (FH) by different relative types and risk of upper gastrointestinal (UGI) cancers has been only rarely reported; the data on UGI cancer survival are sparse...
  9. pmc Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma
    Li yan Xue
    Department of Pathology, Cancer Institute Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
    BMC Cancer 6:296. 2006
    ..In this study, we are interested in investigating the expression of a variety of functional classes of proteins in ESCC and its precursor lesions and characterizing the correlation of these proteins with ESCC malignant progression...
  10. ncbi request reprint Prospective study of serum vitamin E levels and esophageal and gastric cancers
    Philip R Taylor
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 8314, USA
    J Natl Cancer Inst 95:1414-6. 2003
    ..89 to 4.75) for GNCC. Serum gamma-tocopherol level was not associated with the incidence of any of these cancers. Our findings provide support for the role of alpha-tocopherol in the etiology of upper gastrointestinal cancers...
  11. ncbi request reprint Nutritional interventions in cancer prevention
    Philip R Taylor
    National Cancer Institute, 6116 Executive Blvd, Rm 705, Bethesda, MD 20892 8314, USA
    J Clin Oncol 23:333-45. 2005
    ....
  12. ncbi request reprint Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity
    Farin Kamangar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3034, Bethesda, MD 20892 7232, USA
    J Natl Cancer Inst 98:1445-52. 2006
    ..pylori strain differences are less clear. We conducted a prospective nested case-control study of H. pylori serology to address these questions...
  13. ncbi request reprint Dietary factors of one-carbon metabolism and prostate cancer risk
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20892, USA
    Am J Clin Nutr 84:929-35. 2006
    ..Vitamin B-6, vitamin B-12, methionine, and alcohol can influence folate-related metabolism...
  14. pmc Genomic characterization of esophageal squamous cell carcinoma from a high-risk population in China
    Nan Hu
    Division of Cancer Epidemiology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 7236, USA
    Cancer Res 69:5908-17. 2009
    ..Our findings show the potential utility of combining CN analysis and gene expression data to identify genes involved in esophageal carcinogenesis...
  15. ncbi request reprint Allelotyping of esophageal squamous-cell carcinoma on chromosome 13 defines deletions related to family history
    Nan Hu
    National Cancer Institute, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Genes Chromosomes Cancer 44:271-8. 2005
    ..Taken together, these data indicate that a gene or genes on chromosome 13 play an important role in the etiology and progression of ESCC...
  16. ncbi request reprint Polymorphisms in inflammation-related genes and risk of gastric cancer (Finland)
    Farin Kamangar
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892 7232, USA
    Cancer Causes Control 17:117-25. 2006
    ..Our results do not support the hypothesis that polymorphisms in genes involved in the inflammatory response confer differences in gastric cancer risk among different individuals...
  17. ncbi request reprint Comprehensive characterization of annexin I alterations in esophageal squamous cell carcinoma
    Nan Hu
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892 8314, USA
    Clin Cancer Res 10:6013-22. 2004
    ..The purpose is to characterize alterations of the annexin I gene, its mRNA, and protein expression in esophageal squamous cell carcinoma...
  18. ncbi request reprint High frequency of CDKN2A alterations in esophageal squamous cell carcinoma from a high-risk Chinese population
    Nan Hu
    Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892 7236, USA
    Genes Chromosomes Cancer 39:205-16. 2004
    ..Only one alteration was observed in CDKN2B, G171A in the 5' untranslated region. Both mutation and intragenic allelic loss in CDKN2A appear to play a role in the development of ESCC...
  19. ncbi request reprint Tooth loss is associated with increased risk of gastric non-cardia adenocarcinoma in a cohort of Finnish smokers
    Christian C Abnet
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Scand J Gastroenterol 40:681-7. 2005
    ..pylori seropositivity...
  20. pmc Prospective study of serum 25-hydroxyvitamin D concentration and mortality in a Chinese population
    Shih Wen Lin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Am J Epidemiol 176:1043-50. 2012
    ..Results were similar for men and women. This study showed that prediagnostic serum 25(OH)D concentrations were not associated with all-cause or cause-specific mortality rates in this Chinese population who had low levels of vitamin D...
  21. pmc Serum ghrelin is inversely associated with risk of subsequent oesophageal squamous cell carcinoma
    Gwen Murphy
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20892, USA
    Gut 61:1533-7. 2012
    ..Ghrelin, a hormone which, is also produced in the gastric fundic glands may be a marker of gastric atrophy, but its association with OSCC is not known...
  22. ncbi request reprint Polymorphisms in interleukin -2, -6, and -10 are not associated with gastric cardia or esophageal cancer in a high-risk chinese population
    Sharon A Savage
    Pediatric Oncology Branch, Center for Cancer Research, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 13:1547-9. 2004
  23. ncbi request reprint Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    Margaret E Wright
    Nutritional Epidemiology Branch and the Genetic Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 84:1200-7. 2006
    ..Little is known, however, about the relation between mortality and circulating concentrations of vitamin E resulting from dietary intake, low-dose supplementation, or both...
  24. pmc One-carbon metabolism biomarkers and risk of colon and rectal cancers
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Nutritional Epidemiology Branch, Suite 320, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:3233-40. 2008
    ..Folate intake has been associated with reduced colorectal cancer risk; however, few studies have prospectively examined circulating folate or other related one-carbon biomarkers...
  25. pmc The relationship between serum ghrelin and the risk of gastric and esophagogastric junctional adenocarcinomas
    Gwen Murphy
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 3034, Rockville, MD 20892, USA
    J Natl Cancer Inst 103:1123-9. 2011
    ..However, the relationship between ghrelin and the risk of gastric and esophagogastric junctional cancers has not been investigated...
  26. pmc Serum cytokine analysis in a positive chemoprevention trial: selenium, interleukin-2, and an association with squamous preneoplastic disease
    Mark J Roth
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Cancer Prev Res (Phila) 3:810-7. 2010
    ..The favorable effect of selenomethionine on esophageal dysplasia in the original trial may have been mediated in part by its effect in reducing the levels of IL-2...
  27. ncbi request reprint Polymorphic variation of Cyp1A1 is associated with the risk of gastric cardia cancer: a prospective case-cohort study of cytochrome P-450 1A1 and GST enzymes
    Mark J Roth
    NIH, NCI, CCR, Cancer Prevention Studies Branch, Bethesda, MD 20892, USA
    Cancer Causes Control 15:1077-83. 2004
    ..To determine if genetic polymorphisms of CYP1A1, GSTM1, GSTP1, or GSTT1 are associated with an increased risk of developing esophageal squamous cell carcinoma (ESCC), gastric cardia cancer (GCC), or either in a high-risk Asian population...
  28. pmc Helicobacter pylori seropositivity and risk of lung cancer
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 7:e32106. 2012
    ..pylori seropositivity. Despite earlier small studies suggesting that H. pylori may contribute to lung carcinogenesis, H. pylori seropositivity does not appear to be associated with lung cancer...
  29. ncbi request reprint Serum alpha-tocopherol and gamma-tocopherol in relation to prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:396-9. 2005
    ..Participants with higher circulating concentrations of the major vitamin E fractions, alpha-tocopherol and gamma-tocopherol, had similarly lower prostate cancer risk...
  30. ncbi request reprint Serum and dietary vitamin E in relation to prostate cancer risk
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1253-9. 2007
    ..In summary, higher prediagnostic serum concentrations of alpha-tocopherol, but not dietary vitamin E, was associated with lower risk of developing prostate cancer, particularly advanced prostate cancer...
  31. ncbi request reprint Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland)
    Karen Woodson
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 7058, USA
    Cancer Causes Control 14:513-8. 2003
    ..We hypothesized that MnSOD may be associated with prostate cancer and that long-term antioxidant supplementation (alpha-tocopherol 50 mg/day for five to eight years) could modify the effect on risk...
  32. ncbi request reprint Genome-wide association study in esophageal cancer using GeneChip mapping 10K array
    Nan Hu
    Cancer Prevention Studies Branch, Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 65:2542-6. 2005
    ..In conclusion, we have shown the feasibility of the Affymetrix 10K SNP array in genome-wide association studies of common cancers and identified new candidate loci to study in ESCC...
  33. pmc Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array
    Nan Hu
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, USA
    BMC Genomics 7:299. 2006
    ..Esophageal squamous cell carcinoma (ESCC) is a common malignancy worldwide. Comprehensive genomic characterization of ESCC will further our understanding of the carcinogenesis process in this disease...
  34. pmc Serum pepsinogens and Helicobacter pylori in relation to the risk of esophageal squamous cell carcinoma in the alpha-tocopherol, beta-carotene cancer prevention study
    Michael B Cook
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Bethesda, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 19:1966-75. 2010
    ..Helicobacter pylori can induce gastric atrophy in humans, which in turn increases gastric cancer risk. Whether H. pylori and gastric atrophy also affect the risk of esophageal squamous cell carcinoma (ESCC), however, remains unresolved...
  35. ncbi request reprint Effects of alcohol on insulin-like growth factor I and insulin-like growth factor binding protein 3 in postmenopausal women
    Jackie A Lavigne
    National Cancer Institute, Bethesda, MD 20892 4264, USA
    Am J Clin Nutr 81:503-7. 2005
    ..Studies have suggested that alcohol may affect IGF-I or IGFBP-3; however, controlled feeding studies to assess alcohol's effects on IGF-I or IGFBP-3 have not been conducted...
  36. pmc Replication of a genome-wide case-control study of esophageal squamous cell carcinoma
    David Ng
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rm 7112, Bethesda, MD 20892 7236, USA
    Int J Cancer 123:1610-5. 2008
    ....
  37. pmc Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China
    Jian Zhong Shou
    Pathology Laboratory, Advanced Technology Center, National Cancer Institute, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 17:1424-35. 2008
    ..The strong relation of LAMC2 pattern of protein expression to survival suggests a role in prognosis, whereas the association of CDC25B with morphologic progression indicates a potential role as an early detection marker...
  38. ncbi request reprint Esophageal and gastric cardia cancer risk and folate- and vitamin B(12)-related polymorphisms in Linxian, China
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
    Cancer Epidemiol Biomarkers Prev 12:1222-6. 2003
    ..59; 95% CI, 1.04-2.42). No association was observed for GCA. Our results suggest that the MTHFR C677T and MTRR A66G polymorphisms influence the risk of ESCC and GCA in this population...
  39. ncbi request reprint Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China
    Christian C Abnet
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 7058, USA
    Cancer Causes Control 14:645-55. 2003
    ....
  40. pmc Genetic variants in fas signaling pathway genes and risk of gastric cancer
    Paula L Hyland
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD, USA Cancer Prevention Fellowship Program, Division of Cancer Prevention, NCI, NIH, Bethesda, MD, USA
    Int J Cancer 134:822-31. 2014
    ..As one of the first attempts to investigate a pathway-level association, our results suggest that these genes and the Fas signaling pathway warrant further evaluation in relation to GC risk in other populations. ..
  41. ncbi request reprint Gene expression differences in normal esophageal mucosa associated with regression and progression of mild and moderate squamous dysplasia in a high-risk Chinese population
    Nina Joshi
    Genetics Branch, Center for Cancer Research, National Cancer Institute NIH, EPS, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Res 66:6851-60. 2006
    ..These data suggest that local and systemic immune responses may influence the natural history of esophageal squamous dysplasia...
  42. pmc Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
    Nan Hu
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    BMC Genomics 11:576. 2010
    ..In the current study we focused on copy number neutral (CN = 2) LOH (CNNLOH) and its relation to gene expression in ESCC...
  43. ncbi request reprint Serum concentrations of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and risk of primary liver cancer
    Katherine A McGlynn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPS 7060, 6120 Executive Blvd, Rockville, MD 20852 7234, USA
    J Natl Cancer Inst 98:1005-10. 2006
    ..Whether DDT and DDE are associated with hepatocarcinogenesis in humans is not clear...
  44. ncbi request reprint Prospective study of alcohol drinking and renal cell cancer risk in a cohort of finnish male smokers
    Somdat Mahabir
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Suite 705, MSC 8314, Bethesda, MD 20892 7058, USA
    Cancer Epidemiol Biomarkers Prev 14:170-5. 2005
    ..Because most of the risk reductions were seen at the highest quartile of alcohol intake and alcohol is a risk factor for a number of cancers particularly among smokers, these data should be interpreted with caution...
  45. ncbi request reprint beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer
    Mark J Roth
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD 20892, USA
    Genes Chromosomes Cancer 44:423-8. 2005
    ..These results show an increase in the minor mRNA (16B) isoform and changes in the expression of downstream markers consistent with increased transcription during the histological progression from normal to squamous dysplasia...
  46. pmc Genetic variants in sex hormone metabolic pathway genes and risk of esophageal squamous cell carcinoma
    Paula L Hyland
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Rockville, MA 20852
    Carcinogenesis 34:1062-8. 2013
    ..These positive findings warrant further evaluation in relation to ESCC risk and replication in other populations...
  47. pmc Serum 25(OH)-vitamin D concentration and risk of esophageal squamous dysplasia
    Christian C Abnet
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Boulevard, EPS 320, MSC 7232, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 16:1889-93. 2007
    ..Previous studies using a variety of measures for vitamin D exposure have reached different conclusions about the association between vitamin D and the risk of developing esophageal cancer...
  48. pmc Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese population
    Wen Qing Li
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 8:e68999. 2013
    ..05). Our data suggest an association between specific genes in the EGFR signaling pathway and risk of GC and ESCC. Further studies are warranted to validate these associations and to investigate underlying mechanisms. ..
  49. ncbi request reprint Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma
    Sharon A Savage
    Section on Genomic Variation, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Gaithersburg, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 13:2251-7. 2004
    ..These variants could confer an altered IL8 expression pattern or interact with environmental factors to increase the risk for inflammation and GCC...
  50. ncbi request reprint Self-reported goiter is associated with a significantly increased risk of gastric noncardia adenocarcinoma in a large population-based Chinese cohort
    Christian C Abnet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 119:1508-10. 2006
    ..37 (0.97, 1.94). Our findings are consistent with the hypothesis that iodine deficiency is associated with an increased risk of gastric cancer...
  51. pmc Iron in relation to gastric cancer in the Alpha-tocopherol, Beta-carotene Cancer Prevention Study
    Michael B Cook
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS Suite 550 Room 5014, Bethesda, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 21:2033-42. 2012
    ..We used the prospective Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study to assess whether iron metrics were associated with gastric cardia cancer (GCC) and gastric noncardia cancer (GNCC)...
  52. ncbi request reprint Zinc concentration in esophageal biopsy specimens measured by x-ray fluorescence and esophageal cancer risk
    Christian C Abnet
    Cancer Prevention Studies Branch, National Cancer Institute, National Institutes of Health, 6116 Executive Blvd, Rm 705, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:301-6. 2005
    ....
  53. pmc Advanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 20:1430-8. 2011
    ..AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement...
  54. ncbi request reprint Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985
    Hilde E van Gijssel
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, NIH, 37 Convent Dr, MSC 4255, Bethesda, MD 20892 4255, USA
    Mutat Res 547:55-62. 2004
    ....
  55. pmc Prospective study of serum cysteine levels and oesophageal and gastric cancers in China
    Gwen Murphy
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Gut 60:618-23. 2011
    ..To examine the relationship between serum cysteine concentration and risk of these cancers we conducted a nested case-cohort study within the General Population Nutrition Intervention Trial in Linxian, China...
  56. pmc The gastric cardia is not a target for human papillomavirus-induced carcinogenesis
    Jill Koshiol
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7070, Rockville, MD 20852 7248, USA
    Cancer Epidemiol Biomarkers Prev 19:1137-9. 2010
    ..Given the availability of an effective HPV vaccine and its potential to prevent HPV-associated cancer, we decided to evaluate the prevalence of HPV DNA in GCA...
  57. ncbi request reprint Lung cancer chemoprevention: a randomized, double-blind trial in Linxian, China
    Farin Kamangar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 3034, Bethesda, MD 10892 7232, USA
    Cancer Epidemiol Biomarkers Prev 15:1562-4. 2006
    ..Supplementation with combinations of vitamins and minerals at nutrient-repletion levels for 5.25 years did not reduce lung cancer mortality in this nutrient-inadequate population in Linxian, China...
  58. pmc Index-based dietary patterns and risk of head and neck cancer in a large prospective study
    Wen Qing Li
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD W QL, YP, JWW, AMG, PRT, NDF, and CCA, and AARP, Washington, DC ARH
    Am J Clin Nutr 99:559-66. 2014
    ..Studies of dietary patterns that examine overall diets may provide broader insight than studies of individual foods. Little is known about the association between dietary patterns and risk of HNC...
  59. ncbi request reprint p16, MGMT, RARbeta2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions
    Mark J Roth
    National Cancer Institute, 6120 Executive Blvd, EPS 320, MSC 7232, Rockville, MD 20892, USA
    Oncol Rep 15:1591-7. 2006
    ..Balloon cytology may be able to screen the length of the esophagus effectively for a subset of cells with abnormal methylation, and may be useful in a primary screening test for ESCC and its precursor lesions...
  60. pmc Risk factors for esophageal and gastric cancers in Shanxi Province, China: a case-control study
    Ying Gao
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Cancer Epidemiol 35:e91-9. 2011
    ..Smoking and alcohol consumption explain little of the risk for upper-gastrointestinal (UGI) cancer in China, where over half of all cases in the world occur...
  61. pmc Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective study
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Cancer Res 71:3582-9. 2011
    ..46 (0.23-0.73), P(trend) = 0.002]. Further adjustment for glucose or insulin levels did not change the observed associations. Our findings suggest that sRAGE is inversely associated with pancreatic cancer risk among Finnish male smokers...
  62. pmc Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes
    Hua Su
    Genetic Epidemiology Branch, DCEG, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Clin Cancer Res 17:2955-66. 2011
    ..Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with poor prognosis. Understanding molecular changes in ESCC will enable identification of molecular subtypes and provide potential targets for early detection and therapy...
  63. ncbi request reprint Tooth loss is associated with increased risk of total death and death from upper gastrointestinal cancer, heart disease, and stroke in a Chinese population-based cohort
    Christian C Abnet
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Epidemiol 34:467-74. 2005
    ..Tooth loss has previously been associated with a higher risk of cancer, heart disease, and stroke, but the role of confounding by smoking remains an issue...
  64. ncbi request reprint Effects of alpha-tocopherol and beta-carotene supplementation on upper aerodigestive tract cancers in a large, randomized controlled trial
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer 109:891-8. 2007
    ..Although smoking and alcohol consumption are the major risk factors for upper aerodigestive tract cancers, observational studies indicate a protective role for fruits, vegetables, and antioxidant nutrients...
  65. pmc Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran
    Behnoush Abedi-Ardekani
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rm 3018, Bethesda, MD 20892 7232, USA
    Gut 59:1178-83. 2010
    ....
  66. pmc Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma
    Mikiko Takikita
    Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 4605, USA
    Anticancer Res 31:945-52. 2011
    ..Several studies have suggested that fascin, cytokeratin 14 and cytokeratin 4 may have significant roles as biomarkers for the progression and survival of esophageal squamous cell carcinoma (ESCC)...
  67. ncbi request reprint Human papillomavirus serology and the risk of esophageal and gastric cancers: results from a cohort in a high-risk region in China
    Farin Kamangar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Int J Cancer 119:579-84. 2006
    ..4). For HPV 73, these figures were 1.3 (0.6-2.5), 1.2 (0.6-2.3) and 0.9 (0.4-2.1). The results of this study do not support a major role for HPV 16, HPV 18 and HPV 73 in the etiology of esophageal and gastric cancers in Linxian, China...
  68. pmc Prediagnostic adiponectin concentrations and pancreatic cancer risk in male smokers
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20852, USA
    Am J Epidemiol 168:1047-55. 2008
    ..lowest, odds ratio = 0.55, 95% confidence interval: 0.31, 0.98; P-trend = 0.03). These results support the hypothesis that higher adiponectin concentrations may be inversely associated with the development of pancreatic cancer...
  69. ncbi request reprint Gene expression analysis of esophageal squamous cell carcinoma reveals consistent molecular profiles related to a family history of upper gastrointestinal cancer
    Hua Su
    Cancer Prevention Studies Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 63:3872-6. 2003
    ..001). These data indicate that molecular profiles in esophageal squamous cell carcinoma are highly consistent and that expression patterns in familial cases differ from those in sporadic cases...
  70. pmc Prediagnostic plasma vitamin C and risk of gastric adenocarcinoma and esophageal squamous cell carcinoma in a Chinese population
    Tram Kim Lam
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Genetic Epidemiology Branch TKL and PRT, Nutritional Epidemiology Branch NDF, SMD, and CCA, and the Division of Cancer Control and Population Sciences, Epidemiology and Genomics Research Program TKL, Rockville, MD and the Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People s Republic of China J HF and Y LQ
    Am J Clin Nutr 98:1289-97. 2013
    ..Prospective studies suggested that vitamin C may reduce risks; however, associations are unclear because of limited sample size...
  71. pmc Predictors of fasting serum insulin and glucose and the risk of pancreatic cancer in smokers
    Cari L Meinhold
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 20:681-90. 2009
    ..A history of type 2 diabetes is one of few consistent risk factors for pancreatic cancer. Potentially modifiable factors related to fasting insulin and glucose concentrations may influence pancreatic cancer risk...
  72. pmc Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma
    Christian C Abnet
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    BMC Cancer 4:30. 2004
    ..We wished to examine the prevalence of mtDNA mutation and polymorphism in subjects from this high risk area of China...
  73. ncbi request reprint Cellular immune response is not associated with incident cancer or total mortality: a prospective follow-up
    Mark J Roth
    NIH, NCI, Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, Bethesda, Maryland 20852, USA
    Eur J Cancer Prev 15:548-50. 2006
    ..This implies that immune competence, as measured by these stimulation indices, is not associated with incident cancer or total mortality in this population...
  74. ncbi request reprint Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China
    Gina D Tran
    Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 8314, USA
    Int J Cancer 113:456-63. 2005
    ..General socioeconomic status (SES) is a common denominator in many of these factors and improving SES is a promising approach for reducing the tremendous burden of upper gastrointestinal cancers in Linxian...
  75. ncbi request reprint Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokers
    Dominique S Michaud
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:853-9. 2004
    ..13, 95% confidence interval: 0.70, 1.81 for the highest vs. lowest quartile). These findings suggest that low-level arsenic exposure is unlikely to explain a substantial excess risk of bladder cancer...
  76. ncbi request reprint Fruits, vegetables, and antioxidants and risk of gastric cancer among male smokers
    Mehdi Nouraie
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 14:2087-92. 2005
    ..Tocopherols were associated with higher risk of GCC, whereas dietary intake of fruits, vitamin C, tocopherols, and lycopene seemed protective for GNCC...
  77. ncbi request reprint Dietary factors of one-carbon metabolism in relation to non-Hodgkin lymphoma and multiple myeloma in a cohort of male smokers
    Unhee Lim
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:1109-14. 2006
    ..Our results suggest that high intake of vitamin B12 among heavy smokers may be protective against NHL but warrant further studies, including among nonsmokers...
  78. ncbi request reprint Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Int J Cancer 118:3147-52. 2006
    ..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk...
  79. ncbi request reprint Estimated urine pH and bladder cancer risk in a cohort of male smokers (Finland)
    Margaret E Wright
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Cancer Causes Control 16:1117-23. 2005
    ....
  80. pmc Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma
    Mikiko Takikita
    Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    BMC Cancer 9:310. 2009
    ..The apoptotic pathways have been hypothesized as important in progression of esophageal squamous cell carcinoma (ESCC). We investigated a panel of proteins that regulate apoptosis as candidate of biomarkers of prognosis in ESCC...
  81. ncbi request reprint The influence of genetic polymorphisms in Ahr, CYP1A1, CYP1A2, CYP1B1, GST M1, GST T1 and UGT1A1 on urine 1-hydroxypyrene glucuronide concentrations in healthy subjects from Rio Grande do Sul, Brazil
    Christian C Abnet
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 320, MSC 7232, Rockville, MD 20852, USA
    Carcinogenesis 28:112-7. 2007
    ..10; and a model combining both exposure and genotype information had a total r2 of 0.33. Our results suggest that CYP1B1 genotypes are strongly associated with urine 1-OHPG concentrations in this population...
  82. pmc Atrophic gastritis and the risk of incident colorectal cancer
    Adeyinka O Laiyemo
    Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD, USA
    Cancer Causes Control 21:163-70. 2010
    ..We prospectively examined the association of atrophic gastritis, a pre-malignant condition for gastric cancer and long-term sequelae common to many exposure factors, and the risk of incident CRC...
  83. ncbi request reprint Whole genome-wide association study using affymetrix SNP chip: a two-stage sequential selection method to identify genes that increase the risk of developing complex diseases
    Howard H Yang
    Laboratory of Population Genetics, Center for Cancer Research, NCI, Bethesda, Maryland, USA
    Methods Mol Med 141:23-35. 2008
    ....
  84. ncbi request reprint Physical activity and renal cell cancer risk in a cohort of male smokers
    Somdat Mahabir
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 108:600-5. 2004
    ..18-1.13) (p-value for trend = 0.12). Occupational physical activity was unrelated to renal cell cancer risk. These data suggest that recreational physical activity may play a role in the prevention of renal cell cancer in men...
  85. pmc A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
    Christian C Abnet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 42:764-7. 2010
    ..19 x 10(-15); OR = 1.57), and for those in the noncardia stomach it was absent (P = 0.44; OR = 1.05). Our findings at 10q23 could provide insight into the high incidence of both cancers in China...
  86. ncbi request reprint A multiplex tissue immunoblotting assay for proteomic profiling: a pilot study of the normal to tumor transition of esophageal squamous cell carcinoma
    Joon Yong Chung
    Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:1403-8. 2006
    ..20-fold increased in dysplastic stroma surrounding invasive tumor. These findings suggest that changes in protein expression can be detected during the transition to dysplasia and may be useful biomarkers...
  87. ncbi request reprint Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison
    Alireza Sepehr
    The US National Cancer Institute, Bethesda, MD, USA
    Cancer Lett 213:195-202. 2004
    ..We conclude that it is unlikely that variations in these polymorphic genes are major contributors to the high incidence of EC among Turkomans in Iran...
  88. ncbi request reprint Infrequent mutation in the BRCA2 gene in esophageal squamous cell carcinoma
    Nan Hu
    National Cancer Institute, Bethesda, Maryland 20892, USA
    Clin Cancer Res 8:1121-6. 2002
    ..We aimed to assess whether the tumor suppressor gene BRCA2 was the inactivation target for allelic loss observed on chromosome 13q in ESCC...
  89. ncbi request reprint Identification of somatic mutations of the RNF6 gene in human esophageal squamous cell carcinoma
    H Shuen Lo
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer Res 62:4191-3. 2002
    ..Identification of multiple somatic mutations in RNF6 suggests that RNF6 is a potential tumor suppressor gene involved in the pathogenesis of ESCC...
  90. ncbi request reprint A prospective study of medical conditions, anthropometry, physical activity, and pancreatic cancer in male smokers (Finland)
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7026, USA
    Cancer Causes Control 13:417-26. 2002
    ..To examine the association between several medical conditions, anthropometric measurements, occupational and leisure physical activity, and pancreatic cancer in a cohort of male Finnish smokers...
  91. pmc Assessment of human papillomavirus in lung tumor tissue
    Jill Koshiol
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7248, USA
    J Natl Cancer Inst 103:501-7. 2011
    ..Lung cancer kills more than 1 million people worldwide each year. Whereas several human papillomavirus (HPV)-associated cancers have been identified, the role of HPV in lung carcinogenesis remains controversial...
  92. pmc No role for human papillomavirus in esophageal squamous cell carcinoma in China
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852 7248, USA
    Int J Cancer 127:93-100. 2010
    ..HPV DNA contamination cannot be ruled out as an explanation for high HPV prevalence in ESCC tissue studies with less stringent tissue procurement and processing protocols...
  93. ncbi request reprint Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland
    R Rita Misra
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Suite 700, Bethesda, MD 20892 7058, USA
    Cancer Lett 191:171-8. 2003
    ..Our results suggest that common alterations in single DNA repair genes are not major determinants of lung cancer susceptibility among smokers...
  94. ncbi request reprint Tooth loss, pancreatic cancer, and Helicobacter pylori
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Clin Nutr 78:176-81. 2003
    ..In addition, Helicobacter pylori has been found in dental plaque and has been associated with periodontal disease and pancreatic cancer...
  95. ncbi request reprint Serum insulin-like growth factor I: tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men
    Karen Woodson
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 63:3991-4. 2003
    ..It is possible that serum IGF-I may be serving as a tumor marker rather than an etiologic factor in prostate cancer...
  96. ncbi request reprint Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine
    Stephanie J Weinstein
    Divison of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 12:1271-2. 2003
  97. ncbi request reprint Effects of alcohol and menstrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3
    Jackie A Lavigne
    Laboratory of Biosystems and Cancer, Center for Cancer Research, National Cancer Institute, 9000 Rockville Pike, Building 37, Room 5046, Bethesda, MD 20892 4264, USA
    Cancer Epidemiol Biomarkers Prev 13:2264-7. 2004
    ..This is the first controlled diet study to show that alcohol decreases serum IGF-I in premenopausal women and that IGF-I significantly increases over the course of the menstrual cycle whether or not alcohol is present...
  98. ncbi request reprint Relationship between serum leptin levels and alcohol consumption in a controlled feeding and alcohol ingestion study
    Mark J Roth
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    J Natl Cancer Inst 95:1722-5. 2003
    ....
  99. ncbi request reprint A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland)
    Panagiota N Mitrou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Int J Cancer 120:2466-73. 2007
    ..The results from this large prospective study suggest that intake of calcium or some related component contained in dairy foods is associated with increased prostate cancer risk...
  100. ncbi request reprint Insulin, glucose, insulin resistance, and pancreatic cancer in male smokers
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    JAMA 294:2872-8. 2005
    ..Obesity, diabetes mellitus, and glucose intolerance have been associated with increased pancreatic cancer risk; however, prediagnostic serum insulin concentration has not been evaluated as a predictor of this malignancy...
  101. ncbi request reprint Prospective study of diet and pancreatic cancer in male smokers
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Am J Epidemiol 155:783-92. 2002
    ..03 (p trend = 0.02), respectively). These results support the hypothesis that a high intake of saturated fat may increase the risk of pancreatic cancer in smokers, while greater intakes of energy and carbohydrate may reduce the risk...