Research Topics
Genomes and GenesSpecies | Mikiko TakikitaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
A case of multifocal fibrosclerosis with intracardiac solid massesMikiko Takikita-Suzuki
Department of Pathology, Shiga University of Medical Science, Otsu, Japan
Hum Pathol 37:493-7. 2006..These histological features were similar to that of MFS. The intracardiac masses are interpreted as one of the manifestations of MFS. This is the first case of MFS accompanied with intracardiac solid masses...
Biomarkers of apoptosis and survival in esophageal squamous cell carcinomaMikiko Takikita
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
BMC Cancer 9:310. 2009..The apoptotic pathways have been hypothesized as important in progression of esophageal squamous cell carcinoma (ESCC). We investigated a panel of proteins that regulate apoptosis as candidate of biomarkers of prognosis in ESCC...
Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypesHua Su
Genetic Epidemiology Branch, DCEG, National Cancer Institute, NIH, Bethesda, MD 20892, USA
Clin Cancer Res 17:2955-66. 2011..Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with poor prognosis. Understanding molecular changes in ESCC will enable identification of molecular subtypes and provide potential targets for early detection and therapy...
Fascin and CK4 as biomarkers for esophageal squamous cell carcinomaMikiko Takikita
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 4605, USA
Anticancer Res 31:945-52. 2011..Several studies have suggested that fascin, cytokeratin 14 and cytokeratin 4 may have significant roles as biomarkers for the progression and survival of esophageal squamous cell carcinoma (ESCC)...
Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancerJoon Yong Chung
Tissue Array Research Program and Applied Molecular Pathology Laboratory, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 4605, USA
Hum Pathol 44:472-9. 2013....
Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in ChinaJian Zhong Shou
Pathology Laboratory, Advanced Technology Center, National Cancer Institute, Bethesda, MD 20892 4605, USA
Cancer Epidemiol Biomarkers Prev 17:1424-35. 2008..The strong relation of LAMC2 pattern of protein expression to survival suggests a role in prognosis, whereas the association of CDC25B with morphologic progression indicates a potential role as an early detection marker...
Podoplanin expression in cancerous stroma induces lymphangiogenesis and predicts lymphatic spread and patient survivalHaruhisa Kitano
Laboratory of Pathology, Toyama University Hospital, Toyama, Japan
Arch Pathol Lab Med 134:1520-7. 2010..Recent reports suggest that podoplanin and other proangiogenic molecules are expressed in stromal fibroblasts and myofibroblasts...
Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinomaMikiko Takikita
Tissue Array Research Program, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Transl Med 9:126. 2011..The overexpression of Her2 and Her3 receptors have been identified in various solid tumors, but its prognostic relevance in HNSCC remains controversial...
Validation of proteomic-based discovery with tissue microarraysStephen M Hewitt
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MD, USA
Proteomics Clin Appl 2:1460-6. 2008..The TMA stands at the crossroads of proteomics and pathology, combining formalin-fixed paraffin-embedded tissue as an analyte and IHC as a method of assay...
Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarrayMikiko Takikita
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 8316, USA
Cancer Res 69:2950-5. 2009..Tumor histologies differed in this and Japanese cohorts. The tissue microarray is available to evaluate other biomarkers. Tissue-based surveillance can be used to monitor tumor histology in populations and facilitate applied research...
Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and VermontPetra Lenz
Division of Cancer Epidemiology and Genetics, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD, USA
Cancer Epidemiol Biomarkers Prev 21:1555-64. 2012..Cell-cycle proteins are important predictive markers in urothelial carcinoma but may also exhibit exposure-specific heterogeneity...
Promises and challenges of predictive tissue biomarkersStephen M Hewitt
Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Advanced Technology Center, MSC 4605, Bethesda MD 20892 4605, USA
Biomark Med 1:313-8. 2007....
