Susan E Swedo

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup: separating fact from fiction
    Susan E Swedo
    Pediatrics and Developmental Neuropsychiatry Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Pediatrics 113:907-11. 2004
  2. ncbi request reprint Echocardiographic findings in the PANDAS subgroup
    Lisa A Snider
    Pediatric Developmental and Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 10 Center Dr, Room 4N208, MSC 1255, Bethesda, MD 20892 1255, USA
    Pediatrics 114:e748-51. 2004
  3. ncbi request reprint Annotation: PANDAS: a model for human autoimmune disease
    Susan E Swedo
    National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
    J Child Psychol Psychiatry 46:227-34. 2005
  4. pmc Executive and attention functioning among children in the PANDAS subgroup
    Matthew E Hirschtritt
    National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, Maryland, USA
    Child Neuropsychol 15:179-94. 2009
  5. ncbi request reprint Childhood-onset obsessive-compulsive disorder and tic disorders: case report and literature review
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Child Adolesc Psychopharmacol 13:S81-8. 2003
  6. pmc Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder
    Paul Grant
    Pediatrics and Developmental Neuroscience PDN Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Child Adolesc Psychopharmacol 20:309-15. 2010
  7. doi request reprint An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder
    Paul Grant
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    J Child Adolesc Psychopharmacol 17:761-7. 2007
  8. ncbi request reprint Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone
    Marjorie A Garvey
    Pediatric and Developmental Neuropsychiatry Branch, National Institute of Mental Health, 10 Center Drive, Room 4N208, MSC 1255, Bethesda, MD 20892 1255, USA
    J Child Neurol 20:424-9. 2005
  9. ncbi request reprint Tics and problem behaviors in schoolchildren: prevalence, characterization, and associations
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1255, USA
    Pediatrics 110:331-6. 2002
  10. ncbi request reprint Post-streptococcal autoimmune disorders of the central nervous system
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Curr Opin Neurol 16:359-65. 2003

Detail Information

Publications30

  1. ncbi request reprint The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup: separating fact from fiction
    Susan E Swedo
    Pediatrics and Developmental Neuropsychiatry Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Pediatrics 113:907-11. 2004
  2. ncbi request reprint Echocardiographic findings in the PANDAS subgroup
    Lisa A Snider
    Pediatric Developmental and Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 10 Center Dr, Room 4N208, MSC 1255, Bethesda, MD 20892 1255, USA
    Pediatrics 114:e748-51. 2004
    ....
  3. ncbi request reprint Annotation: PANDAS: a model for human autoimmune disease
    Susan E Swedo
    National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
    J Child Psychol Psychiatry 46:227-34. 2005
    ....
  4. pmc Executive and attention functioning among children in the PANDAS subgroup
    Matthew E Hirschtritt
    National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, Maryland, USA
    Child Neuropsychol 15:179-94. 2009
    ..This study demonstrates that children with PANDAS exhibit neuropsychological profiles similar to those of their primary psychiatric diagnosis...
  5. ncbi request reprint Childhood-onset obsessive-compulsive disorder and tic disorders: case report and literature review
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Child Adolesc Psychopharmacol 13:S81-8. 2003
    ..Further research is required to determine why the treatments are helpful and to ascertain whether or not antibiotic prophylaxis can help prevent poststreptococcal symptom exacerbations...
  6. pmc Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder
    Paul Grant
    Pediatrics and Developmental Neuroscience PDN Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Child Adolesc Psychopharmacol 20:309-15. 2010
    ..It also reports on our experience to date in the study of the drug in children, with emphasis on adverse effects noted so far in these younger patients...
  7. doi request reprint An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder
    Paul Grant
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    J Child Adolesc Psychopharmacol 17:761-7. 2007
    ..Riluzole, a glutamate antagonist, has theoretical support as an alternative pharmacological treatment and has demonstrated possible benefit in some open-label trials in adults with OCD...
  8. ncbi request reprint Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone
    Marjorie A Garvey
    Pediatric and Developmental Neuropsychiatry Branch, National Institute of Mental Health, 10 Center Drive, Room 4N208, MSC 1255, Bethesda, MD 20892 1255, USA
    J Child Neurol 20:424-9. 2005
    ..Larger studies are required to confirm these clinical observations and to determine if these treatments are cost-effective for this disorder...
  9. ncbi request reprint Tics and problem behaviors in schoolchildren: prevalence, characterization, and associations
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1255, USA
    Pediatrics 110:331-6. 2002
    ..We conducted an 8-month longitudinal observational study to determine the variations in frequency of motor tics and associated problem behaviors...
  10. ncbi request reprint Post-streptococcal autoimmune disorders of the central nervous system
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Curr Opin Neurol 16:359-65. 2003
    ..The present review summarizes the most recent published findings of central nervous system diseases that have evidence of a post-streptococcal autoimmune etiology...
  11. ncbi request reprint Antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders
    Lisa A Snider
    Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Biol Psychiatry 57:788-92. 2005
    ..We hypothesized that the prevention of streptococcal infections among children in the PANDAS subgroup would decrease neuropsychiatric symptom exacerbations...
  12. pmc 12-Week, Placebo-Controlled Trial of Add-on Riluzole in the Treatment of Childhood-Onset Obsessive-Compulsive Disorder
    Paul J Grant
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Neuropsychopharmacology 39:1453-9. 2014
    ..However, future studies may show benefits for less treatment-refractory children with fewer concomitant medications. ..
  13. doi request reprint Compared to what? Early brain overgrowth in autism and the perils of population norms
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland Electronic address
    Biol Psychiatry 74:563-75. 2013
    ....
  14. pmc Lack of serum antibodies against Borrelia burgdorferi in children with autism
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    Clin Vaccine Immunol 20:1092-3. 2013
    ..No seropositivity against Borrelia burgdorferi was detected in the children with and without autism. There was no evidence of an association between Lyme disease and autism. ..
  15. pmc Risks of propofol sedation/anesthesia for imaging studies in pediatric research: eight years of experience in a clinical research center
    Ruwan Kiringoda
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, National Institutes of Health Clinical Center, Bethesda, Maryland, USA
    Arch Pediatr Adolesc Med 164:554-60. 2010
    ..To quantify the incidence of adverse events associated with anesthesia given for research-driven imaging studies and to identify risk factors for those events in pediatric research subjects...
  16. pmc Brief report: symptom onset patterns and functional outcomes in young children with autism spectrum disorders
    Stacy Shumway
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, Bethesda, MD 20892 1255, USA
    J Autism Dev Disord 41:1727-32. 2011
    ..Findings indicate that current functioning does not differ according to onset pattern, calling into question the use of onset categorizations for prognostic purposes in children with ASD...
  17. pmc A magnetization transfer imaging study of corpus callosum myelination in young children with autism
    Marta Gozzi
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1255, USA
    Biol Psychiatry 72:215-20. 2012
    ..Here, we used magnetization transfer imaging to provide insight into the myelination of the corpus callosum in children with autism...
  18. ncbi request reprint Prevalence of obsessive-compulsive disorder in patients with systemic lupus erythematosus
    Marcia J Slattery
    National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    J Clin Psychiatry 65:301-6. 2004
    ..The goal of this pilot study was to investigate the prevalence of obsessive-compulsive disorder (OCD) in a group of patients with systemic lupus erythematosus (SLE)...
  19. pmc The importance of autism research
    Audrey Thurm
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Dialogues Clin Neurosci 14:219-22. 2012
    ..This editorial discusses the importance of autism research, noting areas of progress and ongoing challenges and focusing on studies of the etiology, pathophysiology, and treatment of autism spectrum disorders...
  20. ncbi request reprint An immunological marker (D8/17) associated with rheumatic fever as a predictor of childhood psychiatric disorders in a community sample
    Gale Inoff-Germain
    Child Psychiatry Branch, National Institute of Mental Health, NIH, DHHS, Bethesda, Maryland 20892 1600, USA
    J Child Psychol Psychiatry 44:782-90. 2003
    ..Possible associations with other disorders accompanying Sydenham's chorea--hyperactivity, anxiety, and depression, also were explored...
  21. pmc Children with obsessive-compulsive disorder: are they just "little adults"?
    Simran K Kalra
    National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 119:737-46. 2009
    ..Despite advances in this area, further research is needed to understand better the etiopathogenesis of the disorder and to develop new, more effective therapeutic options...
  22. ncbi request reprint Sensitivity of the D8/17 assay
    Charlotte S Hamilton
    Am J Psychiatry 160:1193-4; author reply 1194. 2003
  23. ncbi request reprint Obsessive-compulsive symptoms among patients with Sydenham chorea
    Fernando R Asbahr
    Department of Psychiatry, Laboratory of Medical Investigation LIM 23, University of Sao Paulo Medical School, Brazil
    Biol Psychiatry 57:1073-6. 2005
    ..We hypothesized that OCS occurring in association with SC would be similar to those among patients with tic disorders...
  24. ncbi request reprint Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
    Tanya K Murphy
    Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
    Biol Psychiatry 61:279-84. 2007
    ..Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) research is based on the hypothesis that infections trigger changes in behavior and movement in children...
  25. ncbi request reprint Antibody-mediated neuronal cell signaling in behavior and movement disorders
    Christine A Kirvan
    Department of Biological Sciences, California State University Sacramento, Sacramento, CA 95618 6077, USA
    J Neuroimmunol 179:173-9. 2006
    ..Antibodies against GlcNAc in PANDAS sera were inhibited by lysoganglioside G(M1). Results suggest that antibodies from an infection may signal neuronal cells in some behavioral and movement disorders...
  26. ncbi request reprint Neurocircuitry of disgust and anxiety in obsessive-compulsive disorder: a positron emission tomography study
    Dan J Stein
    Department of Psychiatry, University of Cape Town, Cape Town, South Africa
    Metab Brain Dis 21:267-77. 2006
    ..Functional magnetic resonance imaging (fMRI) studies of disgust-inducing visual stimuli in OCD have suggested disorder specific alterations in brain activation during these tasks...
  27. ncbi request reprint Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea
    Christine A Kirvan
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Nat Med 9:914-20. 2003
    ..The new evidence implicates antibody-mediated neuronal cell signaling in the immunopathogenesis of Sydenham chorea and will lead to a better understanding of other antibody-mediated neurological disorders...
  28. ncbi request reprint Tubulin is a neuronal target of autoantibodies in Sydenham's chorea
    Christine A Kirvan
    Department of Biological Sciences, California State University, Sacramento, CA 95819, USA
    J Immunol 178:7412-21. 2007
    ....
  29. ncbi request reprint Streptococcal mimicry and antibody-mediated cell signaling in the pathogenesis of Sydenham's chorea
    Christine A Kirvan
    California State University, Department of Biological Sciences, Sacramento, CA, USA
    Autoimmunity 39:21-9. 2006
    ..A group of antibodies present in pediatric autoimmune neuropsychiatric disorders (PANDAS) were similar but not identical to the antibodies observed in chorea...
  30. ncbi request reprint Does group A beta-hemolytic streptococcal infection increase risk for behavioral and neuropsychiatric symptoms in children?
    Eliana Miller Perrin
    Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, 200 Mason Farm Road, Chapel Hill, NC 27599 7220, USA
    Arch Pediatr Adolesc Med 158:848-56. 2004
    ..To determine whether group A beta-hemolytic streptococcal infections increase the risk of developing symptoms characteristic of the diagnosis pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS)...