Trey Sunderland

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease
    Trey Sunderland
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    JAMA 289:2094-103. 2003
  2. ncbi request reprint Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele
    Trey Sunderland
    National Institute of Mental Health, Geriatric Psychiatry Branch, Building 10, Room 3N228, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Biol Psychiatry 56:670-6. 2004
  3. ncbi request reprint Stability of CSF beta-amyloid(1-42) and tau levels by APOE genotype in Alzheimer patients
    Edward D Huey
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    Dement Geriatr Cogn Disord 22:48-53. 2006
  4. ncbi request reprint Scaling of visuospatial attention undergoes differential longitudinal change as a function of APOE genotype prior to old age: results from the NIMH BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, and Geriatric Psychiatry Branch, National Institute of Mental Health, USA
    Neuropsychology 19:830-40. 2005
  5. pmc Failing compensatory mechanisms during working memory in older apolipoprotein E-epsilon4 healthy adults
    Francesca M Filbey
    Geriatric Psychiatry Branch, NIMH, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Brain Imaging Behav 4:177-88. 2010
  6. ncbi request reprint Hippocampal atrophy in the healthy is initially linear and independent of age
    Robert M Cohen
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Clinical Research Center 2 5362, MSC 1274, 10 Center Drive, Bethesda MD 20892 1274, USA
    Neurobiol Aging 27:1385-94. 2006
  7. ncbi request reprint Biomarkers in the diagnosis of Alzheimer's disease: are we ready?
    Trey Sunderland
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Geriatr Psychiatry Neurol 19:172-9. 2006
  8. ncbi request reprint Age and APOE-epsilon4 genotype influence the effect of physostigmine infusion on the in-vivo distribution volume of the muscarinic-2-receptor dependent tracer [18F]FP-TZTP
    Robert M Cohen
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Synapse 60:86-92. 2006
  9. ncbi request reprint Effects of previous major depressive illness on cognition in Alzheimer disease patients
    H Eleanor Cannon-Spoor
    Geriatric Psychiatry Branch, NIMH, Bethesda, MD 20892 1274, USA
    Am J Geriatr Psychiatry 13:312-8. 2005
  10. ncbi request reprint Geriatric psychiatry: coming of age in America
    Trey Sunderland
    National Institute of Mental Health 9000 Rockville Pike Building 10, Room 3N228 Bethesda, Maryland 20892, USA
    Biol Psychiatry 58:263-4. 2005

Detail Information

Publications26

  1. ncbi request reprint Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease
    Trey Sunderland
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    JAMA 289:2094-103. 2003
    ..The search for antemortem biomarkers is intense and has focused on cerebrospinal fluid (CSF) beta-amyloid1-42 and tau proteins...
  2. ncbi request reprint Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele
    Trey Sunderland
    National Institute of Mental Health, Geriatric Psychiatry Branch, Building 10, Room 3N228, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Biol Psychiatry 56:670-6. 2004
    ..We tested these CSF markers in groups of subjects with AD and healthy older control subjects, using the absence or presence of the APOE epsilon4 allele as a predictive variable in the search for possible prognostic biomarkers of AD...
  3. ncbi request reprint Stability of CSF beta-amyloid(1-42) and tau levels by APOE genotype in Alzheimer patients
    Edward D Huey
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    Dement Geriatr Cogn Disord 22:48-53. 2006
    ..Cerebrospinal fluid (CSF) measures of beta-amyloid(1-42 )and tau differ between patients with Alzheimer's Disease (AD) and elderly normal controls. The effect of time and APOE genotype on these biomarkers continues to be elucidated...
  4. ncbi request reprint Scaling of visuospatial attention undergoes differential longitudinal change as a function of APOE genotype prior to old age: results from the NIMH BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, and Geriatric Psychiatry Branch, National Institute of Mental Health, USA
    Neuropsychology 19:830-40. 2005
    ..However, cognitive decline in midlife associated with a gene modulating neuronal response to insult argues that the concept of an AD prodrome includes factors that allow as well as cause AD...
  5. pmc Failing compensatory mechanisms during working memory in older apolipoprotein E-epsilon4 healthy adults
    Francesca M Filbey
    Geriatric Psychiatry Branch, NIMH, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Brain Imaging Behav 4:177-88. 2010
    ..This effect, however, appears to diminish with age...
  6. ncbi request reprint Hippocampal atrophy in the healthy is initially linear and independent of age
    Robert M Cohen
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Clinical Research Center 2 5362, MSC 1274, 10 Center Drive, Bethesda MD 20892 1274, USA
    Neurobiol Aging 27:1385-94. 2006
    ....
  7. ncbi request reprint Biomarkers in the diagnosis of Alzheimer's disease: are we ready?
    Trey Sunderland
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Geriatr Psychiatry Neurol 19:172-9. 2006
    ..The current biomarker approaches to diagnosis are reviewed along with a special emphasis on near-term recommendations and further research directions...
  8. ncbi request reprint Age and APOE-epsilon4 genotype influence the effect of physostigmine infusion on the in-vivo distribution volume of the muscarinic-2-receptor dependent tracer [18F]FP-TZTP
    Robert M Cohen
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Synapse 60:86-92. 2006
    ....
  9. ncbi request reprint Effects of previous major depressive illness on cognition in Alzheimer disease patients
    H Eleanor Cannon-Spoor
    Geriatric Psychiatry Branch, NIMH, Bethesda, MD 20892 1274, USA
    Am J Geriatr Psychiatry 13:312-8. 2005
    ....
  10. ncbi request reprint Geriatric psychiatry: coming of age in America
    Trey Sunderland
    National Institute of Mental Health 9000 Rockville Pike Building 10, Room 3N228 Bethesda, Maryland 20892, USA
    Biol Psychiatry 58:263-4. 2005
  11. ncbi request reprint Views of potential subjects toward proposed regulations for clinical research with adults unable to consent
    Dave Wendler
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892 1156, USA
    Am J Psychiatry 159:585-91. 2002
    ..The authors' goal was to assess healthy individuals' attitudes toward five of the most prominent proposed safeguards regarding the consent process for research with adults unable to consent...
  12. ncbi request reprint Context-specific memory and apolipoprotein E (ApoE) epsilon 4: cognitive evidence from the NIMH prospective study of risk for Alzheimer's disease
    James A Levy
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Int Neuropsychol Soc 10:362-70. 2004
    ....
  13. ncbi request reprint The use of biomarkers in the elderly: current and future challenges
    Trey Sunderland
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 58:272-6. 2005
    ..While some progress has been made in the search for adequate biomarkers in the elderly, in particular with Alzheimer disease, much more work is needed before these potential biomarkers can be reliably used in clinical practice...
  14. ncbi request reprint A magnetoencephalography spatiotemporal analysis of neural activities during feature binding
    Francesca M Filbey
    Geriatric Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Neuroreport 16:1747-52. 2005
    ..Theta band synchronization was observed in many of these same areas, but also in other areas not noted to have increased theta band power suggesting a broad network of regions subserving the encoding phase of feature binding...
  15. ncbi request reprint Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life
    Dennis S Charney
    National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Arch Gen Psychiatry 60:664-72. 2003
    ..To review progress made during the past decade in late-life mood disorders and to identify areas of unmet need in health care delivery and research...
  16. ncbi request reprint Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-epsilon4 allele
    Robert M Cohen
    Geriatric Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Synapse 49:150-6. 2003
    ..65, P < 0.06). A lower concentration of acetylcholine in the synapse of APOE-epsilon4+ older individuals is a likely explanation for the greater [(18)F]FP-TZTP distribution volumes...
  17. pmc The apolipoprotein E gene, attention, and brain function
    Raja Parasuraman
    Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064, USA
    Neuropsychology 16:254-74. 2002
    ....
  18. ncbi request reprint A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's disease
    George S Zubenko
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Room E1230, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Psychiatry 160:857-66. 2003
    ....
  19. pmc Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults: results From the National Institute of Mental Health's BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, USA
    Neuropsychology 19:199-211. 2005
    ..Effects of APOE genotype on component processes of cognition in healthy, middle-aged adults is consistent with the emergence in adulthood of an APOE-epsilon4 cognitive phenotype...
  20. ncbi request reprint Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Neurosci Lett 391:48-50. 2005
    ..Our study indicates that the apoE epsilon4 carrier status should be considered when CSF P-tau(231P) is evaluated as biomarker candidate of AD in MCI subjects...
  21. ncbi request reprint Apolipoprotein E and category fluency: evidence for reduced semantic access in healthy normal controls at risk for developing Alzheimer's disease
    Virginia M Rosen
    Department of Psychology, Syracuse University, 430 Huntington Hall, Syracuse, NY 13244, USA
    Neuropsychologia 43:647-58. 2005
    ....
  22. ncbi request reprint Alzheimer disease
    Trey Sunderland
    South Med J 98:588-9. 2005
  23. ncbi request reprint Proteomic approaches in drug discovery and development
    Holly D Soares
    Pfizer Global Research and Development, Groton, CT 06340, USA
    Int Rev Neurobiol 61:97-126. 2004
  24. ncbi request reprint Reminiscence group activities and discourse interaction in Alzheimer's disease
    Sharon E Moss
    Research Resources and Advocacy, Speech, Language, Hearing Science and Research Unit, American Speech Language Hearing Association, 10801 Rockville Pike, Rockville, MD 20852, USA
    J Gerontol Nurs 28:36-44. 2002
    ..Results are discussed in terms of their relevance to gerontological nurses managing patients with AD...
  25. pmc Children of persons with Alzheimer disease: what does the future hold?
    Lissy Jarvik
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
    Alzheimer Dis Assoc Disord 22:6-20. 2008
    ..We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring...
  26. ncbi request reprint Development of subtle psychotic symptoms with memantine: a case report
    Edward D Huey
    J Clin Psychiatry 66:658-9. 2005