Research Topics
| Anthony F SuffrediniSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Novel therapies for septic shock over the past 4 decadesAnthony F Suffredini
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bldg 10, Rm 2C145, Bethesda, MD 20892, USA
JAMA 306:194-9. 2011..In this Grand Rounds, we summarize the results of the clinical trials conducted during the last 4 decades, discuss some lessons learned, and suggest possible directions for future investigation...
Quality control of serum albumin depletion for proteomic analysisNitin Seam
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892 1662, USA
Clin Chem 53:1915-20. 2007..We examined the reproducibility of albumin immunodepletion and describe a method of QC for this process...
Bundled care for septic shock: an analysis of clinical trialsAmisha V Barochia
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA
Crit Care Med 38:668-78. 2010..Valid bundles require effective components with additive benefits. Proponents encourage evaluation of bundles, both as a whole and based on the performance of each component...
Rapid induction of autoantibodies during ARDS and septic shockPeter D Burbelo
Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
J Transl Med 8:97. 2010....
ProteomicsGerard T Hoehn
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA
Crit Care Med 33:S444-8. 2005
A canine model of septic shock: balancing animal welfare and scientific relevancePeter C Minneci
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Physiol Heart Circ Physiol 293:H2487-500. 2007..The integration into this model of both specific and supportive titrated therapies routinely used in septic patients may provide a more realistic setting to evaluate therapies for sepsis...
Proteomic identification of altered apolipoprotein patterns in pulmonary hypertension and vasculopathy of sickle cell diseaseSusan Yuditskaya
Pulmonary and Vascular Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1476, USA
Blood 113:1122-8. 2009..These results imply a relationship of apolipoproteins to the development of PAH vasculopathy in SCD, potentially involving an unexpected mechanistic parallel to atherosclerosis, another proliferative vasculopathy...
Influence of IFN-gamma on gene expression in normal human bronchial epithelial cells: modulation of IFN-gamma effects by dexamethasoneRafal Pawliczak
Critical Care Medicine Department, National Institutes of Health, Bethesda, Maryland 20892, USA
Physiol Genomics 23:28-45. 2005..Dex had little effect on the immediate early response to IFN-gamma but a significant effect on the late responses...
Proteomic analysis of inflammatory biomarkers in bronchoalveolar lavageCarlos de Torre
Critical Care Medicine Department, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Proteomics 6:3949-57. 2006..This pattern was also found in ARDS BAL after immunoblot analysis. These approaches will be useful to improve current methods of monitoring lung inflammation and to identify new therapeutic targets...
