Xin Zhuan Su
Affiliation: National Institutes of Health
- Jiang H, Yi M, Mu J, Zhang L, Ivens A, Klimczak L, et al. Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray. BMC Genomics. 2008;9:398 pubmed publisher..Our method for accurate mSFP detection and the mSFP identified will greatly facilitate large-scale studies of genome variation in the P. falciparum parasite and provide useful resources for mapping important parasite traits. ..
- Lu F, Jiang H, Ding J, Mu J, Valenzuela J, Ribeiro J, et al. cDNA sequences reveal considerable gene prediction inaccuracy in the Plasmodium falciparum genome. BMC Genomics. 2007;8:255 pubmed..This study provides valuable information for genome annotation that will be critical for functional analyses. ..
- Yu X, Cai B, Wang M, Tan P, Ding X, Wu J, et al. Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality. Immunity. 2016;45:1093-1107 pubmed publisher..Thus, our findings have identified a critical regulatory mechanism of type I IFN signaling in pDCs and stage-specific function of immune cells in generating potent immunity against lethal YM infection. ..
- Nair S, Xu R, Pattaradilokrat S, Wu J, Qi Y, Zilversmit M, et al. A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence. Nat Commun. 2017;8:223 pubmed publisher..Here the authors comparatively map virulence loci using the offspring from a P. yoelii YM and N67 genetic cross, and identify a putative HECT E3 ubiquitin ligase that may explain the variance. ..