Seong Su Han

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Suppression of phorbol ester-induced NF-kappaB activation by capsaicin in cultured human promyelocytic leukemia cells
    Seong Su Han
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Korea
    Arch Pharm Res 25:475-9. 2002
  2. pmc CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms
    Seong Su Han
    Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Mol Cancer 5:22. 2006
  3. pmc Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1
    Seong Su Han
    Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    Mol Cancer 4:40. 2005
  4. ncbi request reprint Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice
    Sung Sup Park
    Laboratory of Genetics, Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 65:1306-15. 2005
  5. ncbi request reprint Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells
    Seong Su Han
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, South Korea
    J Biochem Mol Biol 35:337-42. 2002
  6. ncbi request reprint L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms
    Seyeon Park
    Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Republic of Korea
    Int J Biochem Cell Biol 36:2180-95. 2004
  7. ncbi request reprint L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60
    Seong Su Han
    Samsung Medical Center, and Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    J Cell Biochem 93:257-70. 2004
  8. ncbi request reprint Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60
    Seong Su Han
    Samsung Medical Center and Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    J Cell Biochem 94:695-707. 2005
  9. ncbi request reprint Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
    Sowmyalakshmi Srinivasan
    Department of Clinical Sciences, College of Health Sciences, University of Kentucky, 900 South Limestone Street, Lexington, KY 40536, USA
    Cancer Res 67:246-53. 2007

Collaborators

  • Siegfried Janz
  • Thomas Ried
  • Louis M Staudt
  • Y Surh
  • Seyeon Park
  • Seong Su Han
  • Sowmyalakshmi Srinivasan
  • Seung Tae Chung
  • Arthur L Shaffer
  • Liangping Peng
  • Je Ho Lee
  • Chan H Park
  • Eun Ryeong Hahm
  • Bruce F Kimler
  • Kihyun Kim
  • Sook J Lee
  • Keunchil Park
  • Won S Kim
  • Sung Soo Yoon
  • Young Sam Keum
  • Rama S Ranga
  • Damodaran Chendil
  • Ravshan Burikhanov
  • Michael B Sporn
  • Wendy DuBois
  • Sung Ho Maeng
  • Jingook Kim
  • Sungho Maeng
  • Chul Won Jung
  • Se Hoon Lee
  • Nicole McNeil
  • Jae Hwan Lim
  • Joong Su Kim
  • Chul W Jung
  • Jung Hyun Yang
  • Hye K Park
  • Hugh D Riordan
  • Neil H Riordan
  • Mark H Lee
  • Kyung Soo Chun
  • Hyo Joung Seo

Detail Information

Publications9

  1. ncbi request reprint Suppression of phorbol ester-induced NF-kappaB activation by capsaicin in cultured human promyelocytic leukemia cells
    Seong Su Han
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Korea
    Arch Pharm Res 25:475-9. 2002
    ..Methylation of the phenolic hydroxyl group of capsaicin abolished its inhibitory effect on NF-kappaB DNA binding. Likewise, TPA-induced activation of AP-1 was mitigated by capsaicin treatment...
  2. pmc CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms
    Seong Su Han
    Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Mol Cancer 5:22. 2006
    ....
  3. pmc Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1
    Seong Su Han
    Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    Mol Cancer 4:40. 2005
    ..The purpose of this study was to establish and characterize a cell line, designated iMycEmu-1, for the in-depth evaluation of LBL in vitro...
  4. ncbi request reprint Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice
    Sung Sup Park
    Laboratory of Genetics, Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 65:1306-15. 2005
    ....
  5. ncbi request reprint Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells
    Seong Su Han
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, South Korea
    J Biochem Mol Biol 35:337-42. 2002
    ..Likewise, the TPA-induced DNA binding of the activator protein-1 (AP-1) was inhibited by curcumin pretreatment...
  6. ncbi request reprint L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms
    Seyeon Park
    Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Republic of Korea
    Int J Biochem Cell Biol 36:2180-95. 2004
    ..In conclusion, LAA can induce apoptosis in AML cells, and this is clearly due to H(2)O(2) which accumulates intracellularly as a result of oxidation of reduced glutathione by LAA...
  7. ncbi request reprint L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60
    Seong Su Han
    Samsung Medical Center, and Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    J Cell Biochem 93:257-70. 2004
    ..In conclusion, our data suggest that LAA exerts its anti-tumor activity through downregulation of NF-kappaB activity and COX-2 expression, and these inhibitory effects can be enhanced by co-treatment with As2O3...
  8. ncbi request reprint Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60
    Seong Su Han
    Samsung Medical Center and Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    J Cell Biochem 94:695-707. 2005
    ..Futhermore, we found that As(2)O(3) also downregulated the expression of COX-2, which has NF-kappaB binding site on its promoter through repressing the NF-kappaB DNA-binding activity...
  9. ncbi request reprint Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
    Sowmyalakshmi Srinivasan
    Department of Clinical Sciences, College of Health Sciences, University of Kentucky, 900 South Limestone Street, Lexington, KY 40536, USA
    Cancer Res 67:246-53. 2007
    ..As Par-4 up-regulation induces apoptosis in most tumor cells, our findings can be extended to high-throughput screens to identify synergistic combinations for both therapy-sensitive and therapy-resistant cancers...