David Sturgill

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Molecular targets for rapid identification of Brucella spp
    Vladyslava G Ratushna
    Department of Computer Science, College of Information Technology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    BMC Microbiol 6:13. 2006
  2. pmc Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila
    Michael J Parisi
    Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
    BMC Genomics 11:346. 2010
  3. pmc Demasculinization of X chromosomes in the Drosophila genus
    David Sturgill
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda Maryland 20892, USA
    Nature 450:238-41. 2007
  4. pmc Global analysis of X-chromosome dosage compensation
    Vaijayanti Gupta
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol 5:3. 2006
  5. pmc Constraint and turnover in sex-biased gene expression in the genus Drosophila
    Yu Zhang
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nature 450:233-7. 2007
  6. pmc Drosophila mojoless, a retroposed GSK-3, has functionally diverged to acquire an essential role in male fertility
    Rasika Kalamegham
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Mol Biol Evol 24:732-42. 2007
  7. pmc Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki)
    David Sturgill
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA
    BMC Bioinformatics 14:320. 2013
  8. pmc Genetic interactions between Drosophila melanogaster menin and Jun/Fos
    Aniello Cerrato
    National Institute of Diabetes and Digestive and Kidney Diseases, Department of Health and Human Services, Bethesda, MD 20892, USA
    Dev Biol 298:59-70. 2006
  9. pmc Comparative genomics of Drosophila and human core promoters
    Peter C FitzGerald
    Genome Analysis Unit, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genome Biol 7:R53. 2006
  10. pmc Core promoter sequences contribute to ovo-B regulation in the Drosophila melanogaster germline
    Beata Bielinska
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Genetics 169:161-72. 2005

Detail Information

Publications13

  1. pmc Molecular targets for rapid identification of Brucella spp
    Vladyslava G Ratushna
    Department of Computer Science, College of Information Technology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    BMC Microbiol 6:13. 2006
    ..We then screened a set of differentiating genes against classical Brucella biovars and showed the applicability of these regions in the design of diagnostic tests...
  2. pmc Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila
    Michael J Parisi
    Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
    BMC Genomics 11:346. 2010
    ..We know little about the coordinated regulation of gene expression patterns in distant somatic tissues that support the developmental cost of gamete production...
  3. pmc Demasculinization of X chromosomes in the Drosophila genus
    David Sturgill
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda Maryland 20892, USA
    Nature 450:238-41. 2007
    ....
  4. pmc Global analysis of X-chromosome dosage compensation
    Vaijayanti Gupta
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol 5:3. 2006
    ..Male germ cells lack MSL complexes, indicating that either germline X-chromosome dosage compensation is MSL-independent, or that germ cells do not carry out dosage compensation...
  5. pmc Constraint and turnover in sex-biased gene expression in the genus Drosophila
    Yu Zhang
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nature 450:233-7. 2007
    ..This higher divergence and turnover of genes with male-biased expression may be due to high transcription rates in the male germline, greater functional pleiotropy of genes expressed in females, and/or sexual competition...
  6. pmc Drosophila mojoless, a retroposed GSK-3, has functionally diverged to acquire an essential role in male fertility
    Rasika Kalamegham
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Mol Biol Evol 24:732-42. 2007
    ..We postulate that mjl has undergone functional diversification and is now under stabilizing selection in the Drosophila genus...
  7. pmc Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki)
    David Sturgill
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA
    BMC Bioinformatics 14:320. 2013
    ..However, methods to analyze splicing are underdeveloped and errors resulting in incorrect splicing calls occur in every experiment...
  8. pmc Genetic interactions between Drosophila melanogaster menin and Jun/Fos
    Aniello Cerrato
    National Institute of Diabetes and Digestive and Kidney Diseases, Department of Health and Human Services, Bethesda, MD 20892, USA
    Dev Biol 298:59-70. 2006
    ..We observed complex genetic interactions between mnn1 and jun in different developmental settings. Our data support the idea that one function of menin is to modulate Jun activity in a manner dependent on the cellular context...
  9. pmc Comparative genomics of Drosophila and human core promoters
    Peter C FitzGerald
    Genome Analysis Unit, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genome Biol 7:R53. 2006
    ..We compare these results with those obtained for human promoters...
  10. pmc Core promoter sequences contribute to ovo-B regulation in the Drosophila melanogaster germline
    Beata Bielinska
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Genetics 169:161-72. 2005
    ..This idea is further supported by the evolutionarily conserved organization of OVO binding sites at or near the start sites of ovo loci in other flies...
  11. ncbi request reprint Comparative validation of the D. melanogaster modENCODE transcriptome annotation
    Zhen Xia Chen
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 24:1209-23. 2014
    ..We report that the vast majority of elements in the annotation are evolutionarily conserved, indicating that the annotation will be an important springboard for functional genetic testing by the Drosophila community. ..
  12. ncbi request reprint Evolution of genes and genomes on the Drosophila phylogeny
    Andrew G Clark
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Nature 450:203-18. 2007
    ..These may prove to underlie differences in the ecology and behaviour of these diverse species...
  13. doi request reprint Evolution of protein-coding genes in Drosophila
    Amanda M Larracuente
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
    Trends Genet 24:114-23. 2008
    ....