Research Topics
Genomes and Genes | David SturgillSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Molecular targets for rapid identification of Brucella sppVladyslava G Ratushna
Department of Computer Science, College of Information Technology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
BMC Microbiol 6:13. 2006..We then screened a set of differentiating genes against classical Brucella biovars and showed the applicability of these regions in the design of diagnostic tests...
Germline-dependent gene expression in distant non-gonadal somatic tissues of DrosophilaMichael J Parisi
Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
BMC Genomics 11:346. 2010..We know little about the coordinated regulation of gene expression patterns in distant somatic tissues that support the developmental cost of gamete production...
Demasculinization of X chromosomes in the Drosophila genusDavid Sturgill
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda Maryland 20892, USA
Nature 450:238-41. 2007....
Global analysis of X-chromosome dosage compensationVaijayanti Gupta
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Biol 5:3. 2006..Male germ cells lack MSL complexes, indicating that either germline X-chromosome dosage compensation is MSL-independent, or that germ cells do not carry out dosage compensation...
Constraint and turnover in sex-biased gene expression in the genus DrosophilaYu Zhang
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Nature 450:233-7. 2007..This higher divergence and turnover of genes with male-biased expression may be due to high transcription rates in the male germline, greater functional pleiotropy of genes expressed in females, and/or sexual competition...
Drosophila mojoless, a retroposed GSK-3, has functionally diverged to acquire an essential role in male fertilityRasika Kalamegham
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
Mol Biol Evol 24:732-42. 2007..We postulate that mjl has undergone functional diversification and is now under stabilizing selection in the Drosophila genus...
Genetic interactions between Drosophila melanogaster menin and Jun/FosAniello Cerrato
National Institute of Diabetes and Digestive and Kidney Diseases, Department of Health and Human Services, Bethesda, MD 20892, USA
Dev Biol 298:59-70. 2006..We observed complex genetic interactions between mnn1 and jun in different developmental settings. Our data support the idea that one function of menin is to modulate Jun activity in a manner dependent on the cellular context...
Comparative genomics of Drosophila and human core promotersPeter C FitzGerald
Genome Analysis Unit, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Genome Biol 7:R53. 2006..CONCLUSION: Drosophila and human promoters use different DNA sequences to regulate gene expression, supporting the idea that evolution occurs by the modulation of gene regulation...
Core promoter sequences contribute to ovo-B regulation in the Drosophila melanogaster germlineBeata Bielinska
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Genetics 169:161-72. 2005..This idea is further supported by the evolutionarily conserved organization of OVO binding sites at or near the start sites of ovo loci in other flies...
Evolution of genes and genomes on the Drosophila phylogenyAndrew G Clark
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Nature 450:203-18. 2007..These may prove to underlie differences in the ecology and behaviour of these diverse species...
Evolution of protein-coding genes in DrosophilaAmanda M Larracuente
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
Trends Genet 24:114-23. 2008....
