M D Stout

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure
    Matthew D Stout
    Toxicology Operations Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicology 244:209-19. 2008
  2. pmc Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years
    M D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, NIEHS, Research Triangle Park, NC 27709, USA
    Food Chem Toxicol 47:729-33. 2009
  3. pmc Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure
    Matthew D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 117:716-22. 2009
  4. pmc Influence of Helicobacter hepaticus infection on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice
    Matthew D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 36:783-94. 2008
  5. doi request reprint Validation and application of a method for the determination of total chromium in rat tissues by inductively coupled plasma mass spectrometry
    Keith E Levine
    RTI International, Research Triangle Park, NC 27709, USA
    Arch Environ Contam Toxicol 58:883-91. 2010
  6. doi request reprint Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal
    Matthew D Stout
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    Toxicol Pathol 36:232-46. 2008

Detail Information

Publications6

  1. pmc Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure
    Matthew D Stout
    Toxicology Operations Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicology 244:209-19. 2008
    ..Hepatocellular adenomas, and adenoma or carcinoma (combined) were increased in male and female mice exposed to 1800ppm. There were also treatment-related increases in multiple adenomas in both sexes...
  2. pmc Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years
    M D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, NIEHS, Research Triangle Park, NC 27709, USA
    Food Chem Toxicol 47:729-33. 2009
    ..In male rats, a statistically significant increase in the incidence of preputial gland adenoma at 10,000 ppm was considered an equivocal finding. CPM was not carcinogenic to female rats or to male or female mice...
  3. pmc Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure
    Matthew D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 117:716-22. 2009
    ..Hexavalent chromium [Cr(VI)] is a human carcinogen after inhalation exposure. Humans also ingest Cr(VI) from contaminated drinking water and soil; however, limited data exist on the oral toxicity and carcinogenicity of Cr(VI)...
  4. pmc Influence of Helicobacter hepaticus infection on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice
    Matthew D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 36:783-94. 2008
    ..These data suggest that in the initial study, H. hepaticusinfluenced the induction of hepatocellular neoplasms in males, but not in females...
  5. doi request reprint Validation and application of a method for the determination of total chromium in rat tissues by inductively coupled plasma mass spectrometry
    Keith E Levine
    RTI International, Research Triangle Park, NC 27709, USA
    Arch Environ Contam Toxicol 58:883-91. 2010
    ..After validation, the method was applied to analyze samples collected in support of two chronic toxicity and carcinogenesis studies conducted by the National Toxicology Program...
  6. doi request reprint Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal
    Matthew D Stout
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    Toxicol Pathol 36:232-46. 2008
    ..These findings suggest that the toxicity of hexenal was limited to the site of contact (stomach) and that the observed DNA adduct formation and cell proliferation occurred in the setting of severe tissue damage...