Mark Stopfer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Sparse odor representation and olfactory learning
    Iori Ito
    National Institute of Child Health and Human Development, US National Institutes of Health, Building 35, Room 3A 102, Bethesda, Maryland 20982, USA
    Nat Neurosci 11:1177-84. 2008
  2. pmc Bilateral olfaction: two is better than one for navigation
    Baranidharan Raman
    National Institute of Child Health and Human Development, NIH, Lincoln Drive, Bethesda, MD 20892, USA
    Genome Biol 9:212. 2008
  3. ncbi request reprint Olfactory processing: massive convergence onto sparse codes
    Mark Stopfer
    NIH NICHD, 35 Lincoln Drive, Rm 3A 102, msc 3715, Bethesda, Maryland 20892, USA
    Curr Biol 17:R363-4. 2007
  4. pmc Frequency transitions in odor-evoked neural oscillations
    Iori Ito
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 64:692-706. 2009
  5. pmc Spontaneous olfactory receptor neuron activity determines follower cell response properties
    Joby Joseph
    National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, MD, USA
    J Neurosci 32:2900-10. 2012
  6. doi request reprint Dye fills reveal additional olfactory tracts in the protocerebrum of wild-type Drosophila
    Nobuaki K Tanaka
    National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
    J Comp Neurol 520:4131-40. 2012
  7. pmc Temporally diverse firing patterns in olfactory receptor neurons underlie spatiotemporal neural codes for odors
    Baranidharan Raman
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 30:1994-2006. 2010
  8. doi request reprint Olfactory coding: tagging and tuning odor-activated synapses for memory
    Zane N Aldworth
    NIH NICHD, Bethesda, MD 20892 USA
    Curr Biol 22:R227-9. 2012
  9. pmc Dual-labeling method for electron microscopy to characterize synaptic connectivity using genetically encoded fluorescent reporters in Drosophila
    Nobuaki K Tanaka
    National Institutes of Health, National Institute of Child Health and Human Development, 35 Lincoln Drive, msc 3715, Bethesda, MD 20892, USA
    J Neurosci Methods 194:312-5. 2011
  10. pmc Peripheral and central olfactory tuning in a moth
    Rose C Ong
    National Institute of Child Health and Human Development, National Institutes of Health, 35 Lincoln Drive, Rm 3A 102, msc 3715, Bethesda, MD 20892, USA
    Chem Senses 37:455-61. 2012

Collaborators

Detail Information

Publications22

  1. pmc Sparse odor representation and olfactory learning
    Iori Ito
    National Institute of Child Health and Human Development, US National Institutes of Health, Building 35, Room 3A 102, Bethesda, Maryland 20982, USA
    Nat Neurosci 11:1177-84. 2008
    ..Thus, spikes in Kenyon cells do not constitute the odor representation that coincides with reinforcement, and Hebbian spike timing-dependent plasticity in Kenyon cells alone cannot underlie this learning...
  2. pmc Bilateral olfaction: two is better than one for navigation
    Baranidharan Raman
    National Institute of Child Health and Human Development, NIH, Lincoln Drive, Bethesda, MD 20892, USA
    Genome Biol 9:212. 2008
    ....
  3. ncbi request reprint Olfactory processing: massive convergence onto sparse codes
    Mark Stopfer
    NIH NICHD, 35 Lincoln Drive, Rm 3A 102, msc 3715, Bethesda, Maryland 20892, USA
    Curr Biol 17:R363-4. 2007
    ..Sparse neural coding provides numerous computational advantages. A recent analysis of the locust olfactory system has revealed a surprising circuit solution for achieving remarkably sparse and specific neural representations of odors...
  4. pmc Frequency transitions in odor-evoked neural oscillations
    Iori Ito
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 64:692-706. 2009
    ..Thus, in the periphery, concentration is encoded mainly by the size of the responsive ORN population, and oscillation frequency is set by the adaptation and saturation of this response...
  5. pmc Spontaneous olfactory receptor neuron activity determines follower cell response properties
    Joby Joseph
    National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, MD, USA
    J Neurosci 32:2900-10. 2012
    ..Our results show how the olfactory system benefits from making a signal detection decision after a point of maximal information convergence, e.g., after KCs pool inputs from many PNs...
  6. doi request reprint Dye fills reveal additional olfactory tracts in the protocerebrum of wild-type Drosophila
    Nobuaki K Tanaka
    National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
    J Comp Neurol 520:4131-40. 2012
    ..We compare our results obtained from wild-type flies with recent results from transgenic strains and discuss how information about odorants is distributed to multiple protocerebral areas...
  7. pmc Temporally diverse firing patterns in olfactory receptor neurons underlie spatiotemporal neural codes for odors
    Baranidharan Raman
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 30:1994-2006. 2010
    ..Thus, our results demonstrate the origin and subsequent reformatting of spatiotemporal neural codes for odors...
  8. doi request reprint Olfactory coding: tagging and tuning odor-activated synapses for memory
    Zane N Aldworth
    NIH NICHD, Bethesda, MD 20892 USA
    Curr Biol 22:R227-9. 2012
    ..A recent study in the locust olfactory system shows how neuromodulators can alter the rules of synaptic plasticity to form associative memories through the use of 'tagged' synapses...
  9. pmc Dual-labeling method for electron microscopy to characterize synaptic connectivity using genetically encoded fluorescent reporters in Drosophila
    Nobuaki K Tanaka
    National Institutes of Health, National Institute of Child Health and Human Development, 35 Lincoln Drive, msc 3715, Bethesda, MD 20892, USA
    J Neurosci Methods 194:312-5. 2011
    ....
  10. pmc Peripheral and central olfactory tuning in a moth
    Rose C Ong
    National Institute of Child Health and Human Development, National Institutes of Health, 35 Lincoln Drive, Rm 3A 102, msc 3715, Bethesda, MD 20892, USA
    Chem Senses 37:455-61. 2012
    ..Together, these results suggest that, although nonpheromonal host plant odors activate broadly distributed responses, they may be linked to attractive behaviors mainly through specific wiring in the brain...
  11. doi request reprint Olfactory coding: giant inhibitory neuron governs sparse odor codes
    Nitin Gupta
    National Institutes of Health, National Institute of Child Health and Human Development, Building 35, 35 Lincoln Drive, Rm 3A 102, msc 3715, Bethesda, MD 20892, USA
    Curr Biol 21:R504-6. 2011
    ..Electrophysiological investigations in locusts have revealed that the sparseness of odor representations, in the brain region expected to mediate olfactory learning, is shaped by a unique inhibitory neuron...
  12. doi request reprint Olfactory coding: non-linear amplification separates smells
    Baranidharan Raman
    National Institutes of Health, National Institute of Child Health and Human Development, 35 Lincoln Drive, Bethesda, Maryland 20892, USA
    Curr Biol 18:R29-32. 2008
    ....
  13. ncbi request reprint Olfactory coding: inhibition reshapes odor responses
    Mark Stopfer
    Laboratory of Cellular and Synaptic Neurophysiology, NICHD, Porter Neuroscience Research Center, Building 35, Room 3A 102, 35 Convent Drive, MSC 3712, Bethesda, Maryland, USA
    Curr Biol 15:R996-8. 2005
    ..Olfactory information is dramatically restructured as it makes its way through the brain. Recent work using a remarkable experimental preparation has revealed how this transformation is achieved...
  14. pmc Functional analysis of a higher olfactory center, the lateral horn
    Nitin Gupta
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 32:8138-48. 2012
    ..Our results rather point to three other possible roles of LHNs: extracting general stimulus features such as odor intensity; mediating bilateral integration of sensory information; and integrating multimodal sensory stimuli...
  15. pmc Insect olfactory coding and memory at multiple timescales
    Nitin Gupta
    NIH NICHD, Bethesda, MD 20892, USA
    Curr Opin Neurobiol 21:768-73. 2011
    ..Our sampling of the olfactory system emphasizes the diversity of memories, and the importance of understanding these memories in the context of computations performed by different parts of a sensory system...
  16. pmc Odor-evoked neural oscillations in Drosophila are mediated by widely branching interneurons
    Nobuaki K Tanaka
    National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 29:8595-603. 2009
    ..We found only the more widely branching population of LNs is necessary for generating odor-elicited oscillations...
  17. ncbi request reprint Olfactory coding: a plastic approach to timing precision
    Rebecca L Vislay-Meltzer
    National Institutes of Health, National Institute of Child Health and Human Development, 35 Lincoln Drive, Bethesda, Maryland 20892, USA
    Curr Biol 17:R797-9. 2007
    ..Spike-timing dependent plasticity has been associated with neural development, learning, and memory. Recently, this mechanism was found to stabilize spike timing relationships across populations of neurons in the locust olfactory system...
  18. ncbi request reprint Encoding a temporally structured stimulus with a temporally structured neural representation
    Stacey L Brown
    National Institute of Child Health and Human Development, US National Institutes of Health, Building 35, Room 3A 102, Bethesda, Maryland 20892, USA
    Nat Neurosci 8:1568-76. 2005
    ..Thus, ensemble-based spatiotemporal coding could disambiguate complex and potentially confounding temporally structured sensory stimuli and thereby provide an invariant response to a stimulus presented in various ways...
  19. pmc Synaptic learning rules and sparse coding in a model sensory system
    Luca A Finelli
    Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS Comput Biol 4:e1000062. 2008
    ....
  20. ncbi request reprint Adaptive regulation of sparseness by feedforward inhibition
    Collins Assisi
    The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Neurosci 10:1176-84. 2007
    ..This simple adaptive mechanism could maintain the sparseness of sensory representations across wide ranges of stimulus conditions...
  21. pmc Fast odor learning improves reliability of odor responses in the locust antennal lobe
    Maxim Bazhenov
    The Salk Institute for Biological Studies, Computational Neurobiology Laboratory, La Jolla, California 92037, USA
    Neuron 46:483-92. 2005
    ..Thus, our study suggests that fast olfactory learning results from stimulus-specific, activity-dependent synaptic facilitation and may improve the signal-to-noise ratio for repeatedly encountered odor stimuli...
  22. ncbi request reprint Intensity versus identity coding in an olfactory system
    Mark Stopfer
    California Institute of Technology, Division of Biology, Computation and Neural Systems Program, Pasadena, CA 91125, USA
    Neuron 39:991-1004. 2003
    ..The tuning of KCs to identity and concentration and the patterning of their responses are consistent with piecewise decoding of their PN inputs over oscillation-cycle length epochs...