W S Stokes

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: state of the science and planning the way forward
    William Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, P O Box 12233, MD K2 16, Research Triangle Park, NC 27709, USA
    Biologicals 40:369-81. 2012
  2. ncbi request reprint Recent progress and future directions for reduction, refinement, and replacement of animal use in veterinary vaccine potency and safety testing: a report from the 2010 NICEATM-ICCVAM International Vaccine Workshop
    W S Stokes
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Dev Biol (Basel) 134:9-21. 2012
  3. doi request reprint Best practices for the use of animals in toxicological research and testing
    William S Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Ann N Y Acad Sci 1245:17-20. 2011
  4. ncbi request reprint Validation of innovative technologies and strategies for regulatory safety assessment methods: challenges and opportunities
    William S Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    ALTEX 27:87-95. 2010
  5. pmc Introduction and summary of the 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies
    W S Stokes
    Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 106:405-12. 1998
  6. ncbi request reprint The role of ICCVAM in evaluating new and alternative test methods
    William S Stokes
    NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, Environmental Toxicology Program, National Institute of Environmental Health Sciences, Mail Code EC 17, PO Box 1233, Research Triangle Park, NC 27709, USA
    Lab Anim (NY) 31:26-32. 2002
  7. ncbi request reprint ICCVAM evaluation of the murine local lymph node assay. Data analyses completed by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods
    K E Haneke
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, MD EC-17, Research Triangle Park, NC 27709, USA
    Regul Toxicol Pharmacol 34:274-86. 2001
  8. ncbi request reprint Validating new toxicology tests for regulatory acceptance
    E Zeiger
    Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Regul Toxicol Pharmacol 27:32-7. 1998
  9. ncbi request reprint ICCVAM evaluation of the murine local lymph node assay. The ICCVAM review process
    D M Sailstad
    Office of Research and Development, National Health and Environmental Effects Research Laboratory, Experimental Toxicology Division, U.S. EPA, MD 92, Research Triangle Park, NC 27711, USA
    Regul Toxicol Pharmacol 34:249-57. 2001
  10. ncbi request reprint Humane endpoints for laboratory animals used in regulatory testing
    William S Stokes
    NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    ILAR J 43:S31-8. 2002

Collaborators

  • Marlies Halder
  • Karen Brown
  • Fabrizio de Mattia
  • Hajime Kojima
  • Charles E Rupprecht
  • J Kulpa-Eddy
  • E Zeiger
  • Robert D Combes
  • Lonnie J King
  • Melanie M Taylor
  • Leonard M Schechtman
  • K E Haneke
  • D M Sailstad
  • James E Nave
  • Travis E Meyer
  • Leonard C Marcus
  • Jay H Glasser
  • Joerg Ohle
  • Thomas P Monath
  • Ronald M Davis
  • Larry R Anderson
  • Carina G Blackmore
  • Marguerite Pappaioanou
  • Roger K Mahr
  • Justin Sobota
  • Michael J Blackwell
  • Elizabeth A Lautner
  • Karen L Siegel
  • Sam S Shekar
  • Nancy Humbert
  • Kristin Brusuelas
  • Ronald Bajuscak
  • David Roach
  • Lisa Agate
  • Brian Griffin
  • Jeffrey Keiser
  • Aaron Kite-Powell
  • Mary Serdula
  • B H Margolin
  • R R Tice
  • B L Carson
  • R N Hill
  • D Hattan

Detail Information

Publications16

  1. doi request reprint Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: state of the science and planning the way forward
    William Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, P O Box 12233, MD K2 16, Research Triangle Park, NC 27709, USA
    Biologicals 40:369-81. 2012
    ..Finally, workshop participants recommended greater international cooperation to expedite development, validation, regulatory acceptance, and implementation of alternative test methods for rabies vaccine potency testing...
  2. ncbi request reprint Recent progress and future directions for reduction, refinement, and replacement of animal use in veterinary vaccine potency and safety testing: a report from the 2010 NICEATM-ICCVAM International Vaccine Workshop
    W S Stokes
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Dev Biol (Basel) 134:9-21. 2012
    ..Implementation of the workshop recommendations is expected to advance new methods for vaccine testing that will benefit animal welfare and ensure continued and improved protection of human and animal health...
  3. doi request reprint Best practices for the use of animals in toxicological research and testing
    William S Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Ann N Y Acad Sci 1245:17-20. 2011
    ..Advances in science and technology are providing opportunities for improved mechanism-based models and integrated safety assessments that will support improved animal welfare and reduce animal use...
  4. ncbi request reprint Validation of innovative technologies and strategies for regulatory safety assessment methods: challenges and opportunities
    William S Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    ALTEX 27:87-95. 2010
    ....
  5. pmc Introduction and summary of the 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies
    W S Stokes
    Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 106:405-12. 1998
    ..These methods will provide for improvements in human health protection, environmental protection, and animal welfare...
  6. ncbi request reprint The role of ICCVAM in evaluating new and alternative test methods
    William S Stokes
    NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, Environmental Toxicology Program, National Institute of Environmental Health Sciences, Mail Code EC 17, PO Box 1233, Research Triangle Park, NC 27709, USA
    Lab Anim (NY) 31:26-32. 2002
  7. ncbi request reprint ICCVAM evaluation of the murine local lymph node assay. Data analyses completed by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods
    K E Haneke
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, MD EC-17, Research Triangle Park, NC 27709, USA
    Regul Toxicol Pharmacol 34:274-86. 2001
    ..The LLNA offered advantages over the GPMT in respect to both the time required to conduct the test and the assay cost...
  8. ncbi request reprint Validating new toxicology tests for regulatory acceptance
    E Zeiger
    Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Regul Toxicol Pharmacol 27:32-7. 1998
    ....
  9. ncbi request reprint ICCVAM evaluation of the murine local lymph node assay. The ICCVAM review process
    D M Sailstad
    Office of Research and Development, National Health and Environmental Effects Research Laboratory, Experimental Toxicology Division, U.S. EPA, MD 92, Research Triangle Park, NC 27711, USA
    Regul Toxicol Pharmacol 34:249-57. 2001
    ..Two related articles in this series of three present the results of the independent peer review evaluation of the LLNA and summarize the performance characteristics of the database substantiating the validity of the LLNA...
  10. ncbi request reprint Humane endpoints for laboratory animals used in regulatory testing
    William S Stokes
    NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    ILAR J 43:S31-8. 2002
    ..Further progress in reducing animal pain and distress resulting from regulatory testing is expected as scientific and technological advances are incorporated into testing procedures and strategies...
  11. ncbi request reprint The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): a review of the ICCVAM test method evaluation process and current international collaborations with the European Centre for the Validation of Alternative Methods (EC
    William S Stokes
    National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Altern Lab Anim 30:23-32. 2002
    ..These collaborations are expected to contribute to accelerated international adoption of harmonised new test methods that will support improved public health and provide for reduced and more-humane use of laboratory animals...
  12. ncbi request reprint Selecting appropriate animal models and experimental designs for endocrine disruptor research and testing studies
    William S Stokes
    US Public Health Service, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
    ILAR J 45:387-93. 2004
    ....
  13. doi request reprint Executive summary of the AVMA One Health Initiative Task Force report
    Lonnie J King
    National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Am Vet Med Assoc 233:259-61. 2008
  14. ncbi request reprint Mobilizing mobile medical units for hurricane relief: the United States Public Health Service and Broward County Health Department response to hurricane Wilma, Broward County, Florida
    Melanie M Taylor
    United States Public Health Services Commissioned Corps, Rockville, Maryland, USA
    J Public Health Manag Pract 13:447-52. 2007
    ..To describe the outcomes of a collaborative response of federal, state, county, and local agencies in conducting syndromic surveillance and delivering medical care to persons affected by the storm through the use of mobile medical units...
  15. ncbi request reprint The international symposium on regulatory testing and animal welfare: recommendations on best scientific practices for subchronic/chronic toxicity and carcinogenicity testing
    Robert Combes
    Fund for Replacement of Animals in Medical Experimentation, Nottingham, UK
    ILAR J 43:S112-7. 2002
  16. ncbi request reprint ECVAM-ICCVAM: prospects for future collaboration
    Leonard M Schechtman
    National Center for Toxicological Research, Food and Drug Administration, Rockville, MD 20857, USA
    Altern Lab Anim 30:227-36. 2002
    ..Opportunities for ECVAM-ICCVAM collaboration are discussed, which illustrate the feasibility and potential benefits of such a partnership...