S Stojanov

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Cytokine profile in PFAPA syndrome suggests continuous inflammation and reduced anti-inflammatory response
    Silvia Stojanov
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur Cytokine Netw 17:90-7. 2006
  2. ncbi Familial autoinflammatory diseases: genetics, pathogenesis and treatment
    Silvia Stojanov
    Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Rheumatol 17:586-99. 2005
  3. ncbi The tumour necrosis factor receptor-associated periodic syndrome: current concepts
    Silvia Stojanov
    Genetics and Genomics Branch, NIAMS, National Institutes of Health, Building 9, Room 1W111, 9 Memorial Drive, Bethesda, MD 20892 0908, USA
    Expert Rev Mol Med 7:1-18. 2005
  4. ncbi Clinical and functional characterisation of a novel TNFRSF1A c.605T>A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercep
    S Stojanov
    Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Building 10, Room 9N210, 10 Center Drive, Bethesda, MD 20892, USA
    Ann Rheum Dis 67:1292-8. 2008
  5. ncbi Incidence and clinical features of hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) and spectrum of mevalonate kinase (MVK) mutations in German children
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstr 55, 45147 Essen, Germany
    Rheumatol Int 32:3253-60. 2012
  6. ncbi Familial Mediterranean fever in Germany: epidemiological, clinical, and genetic characteristics of a pediatric population
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    Eur J Pediatr 171:1775-85. 2012
  7. ncbi Tumor necrosis factor receptor 1-associated periodic syndrome without fever: cytokine profile before and during etanercept treatment
    H Morbach
    Section of pediatric rheumatology and osteology, Children s Hospital, University of Wurzburg, Josef Schneider Str 2, 97080 Wurzburg, Germany
    Rheumatol Int 30:207-12. 2009
  8. ncbi Analysis of cryopyrin-associated periodic syndromes (CAPS) in German children: epidemiological, clinical and genetic characteristics
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Klin Padiatr 222:356-61. 2010
  9. ncbi The hereditary autoinflammatory syndromes
    Puja Chitkara
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Center Drive, Bethesda, MD, USA
    Pediatr Infect Dis J 26:353-4. 2007
  10. ncbi Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenot
    Silvia Stojanov
    Department of Infectious Diseases Immunology, Children s Hospital, University of Munich, Munich, Germany
    Arthritis Rheum 50:1951-8. 2004

Collaborators

Detail Information

Publications14

  1. ncbi Cytokine profile in PFAPA syndrome suggests continuous inflammation and reduced anti-inflammatory response
    Silvia Stojanov
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur Cytokine Netw 17:90-7. 2006
    ....
  2. ncbi Familial autoinflammatory diseases: genetics, pathogenesis and treatment
    Silvia Stojanov
    Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Rheumatol 17:586-99. 2005
    ..This review elucidates how recent advances have impacted diagnosis, pathogenesis, and treatment...
  3. ncbi The tumour necrosis factor receptor-associated periodic syndrome: current concepts
    Silvia Stojanov
    Genetics and Genomics Branch, NIAMS, National Institutes of Health, Building 9, Room 1W111, 9 Memorial Drive, Bethesda, MD 20892 0908, USA
    Expert Rev Mol Med 7:1-18. 2005
    ..Synthetic anti-TNF agents provide a rational form of therapy for TRAPS, and have been shown to delay or indeed prevent development of systemic amyloidosis (AA type), a life-threatening complication in this condition...
  4. ncbi Clinical and functional characterisation of a novel TNFRSF1A c.605T>A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercep
    S Stojanov
    Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Building 10, Room 9N210, 10 Center Drive, Bethesda, MD 20892, USA
    Ann Rheum Dis 67:1292-8. 2008
    ..To study the clinical outcome, treatment response, T-cell subsets and functional consequences of a novel tumour necrosis factor (TNF) receptor type 1 (TNFRSF1A) mutation affecting the receptor cleavage site...
  5. ncbi Incidence and clinical features of hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) and spectrum of mevalonate kinase (MVK) mutations in German children
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstr 55, 45147 Essen, Germany
    Rheumatol Int 32:3253-60. 2012
    ..The most frequent mutation was p.Val377Ile (81%, 13 out of 16). In Germany, the incidence of HIDS is very low with 0.39 per 10(6) person-years...
  6. ncbi Familial Mediterranean fever in Germany: epidemiological, clinical, and genetic characteristics of a pediatric population
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    Eur J Pediatr 171:1775-85. 2012
    ..Twenty-five to 50 FMF patients ≤ 16 years are newly diagnosed per year. The disease is most commonly observed in individuals of Turkish ancestry...
  7. ncbi Tumor necrosis factor receptor 1-associated periodic syndrome without fever: cytokine profile before and during etanercept treatment
    H Morbach
    Section of pediatric rheumatology and osteology, Children s Hospital, University of Wurzburg, Josef Schneider Str 2, 97080 Wurzburg, Germany
    Rheumatol Int 30:207-12. 2009
    ..Hereditary fever syndromes have to be considered in case of chronic unexplained inflammation even if fever is no presenting symptom...
  8. ncbi Analysis of cryopyrin-associated periodic syndromes (CAPS) in German children: epidemiological, clinical and genetic characteristics
    E Lainka
    Department of Paediatric Rheumatology, Children s Hospital, University Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Klin Padiatr 222:356-61. 2010
    ..The aims were to determine the incidence of CAPS and the spectrum of mutations in the NLRP3 (formerly= CIAS1) gene and to describe the clinical manifestations...
  9. ncbi The hereditary autoinflammatory syndromes
    Puja Chitkara
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Center Drive, Bethesda, MD, USA
    Pediatr Infect Dis J 26:353-4. 2007
  10. ncbi Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenot
    Silvia Stojanov
    Department of Infectious Diseases Immunology, Children s Hospital, University of Munich, Munich, Germany
    Arthritis Rheum 50:1951-8. 2004
    ....
  11. ncbi A novel CIAS1 mutation and plasma/cerebrospinal fluid cytokine profile in a German patient with neonatal-onset multisystem inflammatory disease responsive to methotrexate therapy
    Silvia Stojanov
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Munich, Germany
    Pediatrics 114:e124-7. 2004
    ..CSF cytokine levels decreased to normal under corticosteroid and intrathecal methotrexate therapy. When the boy reached the age of 5.5 years, treatment was stopped, and he has remained relapse-free...
  12. ncbi A new low-penetrance TNFRSF1A mutation causing atypical periodic fever
    Anita Rack
    Department of Infectious Diseases and Immunology, Children's Hospital, Munich, Germany
    Pediatr Int 48:169-71. 2006
  13. ncbi Identification of a novel mevalonate kinase gene mutation in combination with the common MVK V377I substitution and the low-penetrance TNFRSF1A R92Q mutation
    Florian Hoffmann
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur J Hum Genet 13:510-2. 2005
    ..The girl was also heterozygous for the TNFRSF1A R92Q low-penetrance mutation, which may have significant proinflammatory effects. However, at the time of presentation, the patient had no TRAPS-associated symptoms...
  14. ncbi Colchicine use in children and adolescents with familial Mediterranean fever: literature review and consensus statement
    Tilmann Kallinich
    Department of Pediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Pediatrics 119:e474-83. 2007
    ..On the basis of this analysis, a consensus statement on the application of colchicine in children and adolescents with familial Mediterranean fever was developed by caregivers from Germany, Austria, and Turkey...