Detail Information
Publications
New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppressionScott M Steward-Tharp
Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann N Y Acad Sci 1183:123-48. 2010..Within this context, we examine existing T cell-directed therapies, including new agents being evaluated in clinical and preclinical studies. We also use recent findings to speculate on novel targets...
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)Kamran Ghoreschi
Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 186:4234-43. 2011..Thus, CP-690,550 may improve autoimmune diseases and prevent transplant rejection by suppressing the differentiation of pathogenic Th1 and Th17 cells as well as innate immune cell signaling...
