Research Topics
Species | Alexandra L SpornSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators |
Detail Information
Publications
Progressive brain volume loss during adolescence in childhood-onset schizophreniaAlexandra L Sporn
Child Psychiatry Branch, NIMH, Bldg 10, Rm 3N202, Bethesda, MD 20892, USA
Am J Psychiatry 160:2181-9. 2003..This study examined the rate of loss in cortical gray matter volume in relation to age and clinical status in adolescent patients over a follow-up period of 2-6 years...
Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory studyAlexandra L Sporn
Child Psychiatry Branch, NIMH, NIH, Bethesda, MD, USA
J Am Acad Child Adolesc Psychiatry 44:925-33. 2005..In this study, the authors examined six weight gain-related hormones in patients with childhood-onset schizophrenia (COS) after 6 weeks of clozapine treatment...
Stimulant drug treatment in childhood-onset schizophrenia with comorbid ADHD: an open-label case seriesJulia W Tossell
Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Building 10, Room 3N202, Bethesda, MD 20892, USA
J Child Adolesc Psychopharmacol 14:448-54. 2004..Our results suggest that ADHD comorbid with COS may be safely treated with a stimulant, once the psychosis is stabilized. A systematic investigation of this question may be warranted...
Clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcomeAlexandra L Sporn
Child Psychiatry Branch, NIMH, Bethesda, MD, USA
J Am Acad Child Adolesc Psychiatry 46:1349-56. 2007..Here we evaluate these as well as other measures in an effort to find predictors of response to clozapine in our early-onset treatment-refractory population...
Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness?Alexandra L Sporn
Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Biol Psychiatry 55:989-94. 2004..In this study, we compared evidence for premorbid PDD as a nonspecific manifestation of impaired neurodevelopment seen in schizophrenia, or as an independent risk factor for COS...
Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specifiedAnjene M Addington
Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1600, USA
Biol Psychiatry 55:976-80. 2004..Childhood-onset schizophrenia (COS), defined as onset of psychotic symptoms by age 12 years, is a rare and severe form of the disorder that seems to be clinically and neurobiologically continuous with the adult disorder...
Repetitive Transcranial Magnetic Stimulation of the Supplementary Motor Area in the treatment of Tourette Syndrome: report of two casesAntonio Mantovani
Clin Neurophysiol 118:2314-5. 2007
