S B Solomon

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Sympathetic blockade in a canine model of gram-negative bacterial peritonitis
    Steven B Solomon
    National Institutes of Health, Bethesda, Maryland 20892, USA
    Shock 19:215-22. 2003
  2. pmc Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin
    Steven B Solomon
    Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA Electronic address
    Free Radic Biol Med 53:2229-39. 2012
  3. pmc Effects of intra-aortic balloon counterpulsation in a model of septic shock
    Steven B Solomon
    Department of Critical Care Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Crit Care Med 37:7-18. 2009
  4. ncbi request reprint Contraction-relaxation coupling: determination of the onset of diastole
    S B Solomon
    Department of Cardiothoracic Surgery and the Department of Biophysics and Physiology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Am J Physiol 277:H23-7. 1999
  5. ncbi request reprint Effective dosing of lipid A analogue E5564 in rats depends on the timing of treatment and the route of Escherichia coli infection
    Steven B Solomon
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 193:634-44. 2006
  6. ncbi request reprint Differing effects of epinephrine, norepinephrine, and vasopressin on survival in a canine model of septic shock
    Peter C Minneci
    Critical Care Medicine Department, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 7D43, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 287:H2545-54. 2004
  7. ncbi request reprint A canine model of septic shock: balancing animal welfare and scientific relevance
    Peter C Minneci
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Physiol Heart Circ Physiol 293:H2487-500. 2007
  8. ncbi request reprint Risk of death does not alter the efficacy of hydrocortisone therapy in a mouse E. coli pneumonia model: risk and corticosteroids in sepsis
    Yan Li
    Critical Care Medicine Department, Clinical Center, Building 10, Room 7D43, National Institutes of Health, Bethesda, MD 20892, USA
    Intensive Care Med 34:568-77. 2008
  9. pmc Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis
    Peter C Minneci
    Department of Surgery, The Children s Institute for Surgical Science, The Children s Hospital of Philadelphia, PA, USA
    Am J Physiol Heart Circ Physiol 295:H743-54. 2008
  10. ncbi request reprint Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock
    Andre C Kalil
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Crit Care Med 34:2719-28. 2006

Detail Information

Publications11

  1. ncbi request reprint Sympathetic blockade in a canine model of gram-negative bacterial peritonitis
    Steven B Solomon
    National Institutes of Health, Bethesda, Maryland 20892, USA
    Shock 19:215-22. 2003
    ....
  2. pmc Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin
    Steven B Solomon
    Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA Electronic address
    Free Radic Biol Med 53:2229-39. 2012
    ..Increases in metHb in the red blood cell, the potential of AS for neurotoxicity, and hypotension would need to be carefully monitored in a clinical trial. ..
  3. pmc Effects of intra-aortic balloon counterpulsation in a model of septic shock
    Steven B Solomon
    Department of Critical Care Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Crit Care Med 37:7-18. 2009
    ..Fluid refractory septic shock can develop into a hypodynamic cardiovascular state in both children and adults. Despite management of these patients with empirical inotropic therapy (with or without a vasodilator), mortality remains high...
  4. ncbi request reprint Contraction-relaxation coupling: determination of the onset of diastole
    S B Solomon
    Department of Cardiothoracic Surgery and the Department of Biophysics and Physiology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Am J Physiol 277:H23-7. 1999
    ....
  5. ncbi request reprint Effective dosing of lipid A analogue E5564 in rats depends on the timing of treatment and the route of Escherichia coli infection
    Steven B Solomon
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 193:634-44. 2006
    ..E5564, a competitive lipid A antagonist, inhibits endotoxin-stimulated inflammation and is under study in patients with sepsis...
  6. ncbi request reprint Differing effects of epinephrine, norepinephrine, and vasopressin on survival in a canine model of septic shock
    Peter C Minneci
    Critical Care Medicine Department, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 7D43, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 287:H2545-54. 2004
    ..In the ranges studied, norepinephrine and vasopressin have more favorable risk-benefit profiles than epinephrine during sepsis...
  7. ncbi request reprint A canine model of septic shock: balancing animal welfare and scientific relevance
    Peter C Minneci
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Physiol Heart Circ Physiol 293:H2487-500. 2007
    ..The integration into this model of both specific and supportive titrated therapies routinely used in septic patients may provide a more realistic setting to evaluate therapies for sepsis...
  8. ncbi request reprint Risk of death does not alter the efficacy of hydrocortisone therapy in a mouse E. coli pneumonia model: risk and corticosteroids in sepsis
    Yan Li
    Critical Care Medicine Department, Clinical Center, Building 10, Room 7D43, National Institutes of Health, Bethesda, MD 20892, USA
    Intensive Care Med 34:568-77. 2008
    ..We investigated whether risk of death altered the effects of hydrocortisone in a mouse pneumonia model...
  9. pmc Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis
    Peter C Minneci
    Department of Surgery, The Children s Institute for Surgical Science, The Children s Hospital of Philadelphia, PA, USA
    Am J Physiol Heart Circ Physiol 295:H743-54. 2008
    ..Nitrite infusions may promote NO generation from Hb while maintaining oxygen delivery; this effect could be harnessed to treat hemolytic conditions and to detoxify Hb-based blood substitutes...
  10. ncbi request reprint Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock
    Andre C Kalil
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Crit Care Med 34:2719-28. 2006
    ..L-arginine supplementation in sepsis is controversial. Septic shock has been alternatively viewed as an L-arginine-deficient state or as a syndrome caused by excess nitric oxide, an end-product of L-arginine metabolism...
  11. pmc Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin
    Peter C Minneci
    Critical Care Medicine Department, NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 115:3409-17. 2005
    ....