Boris P Sokolov

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, National Institutes of Health, DHHS, Baltimore, Maryland 21224, USA
    J Neurosci Res 72:756-67. 2003
  2. ncbi request reprint Methamphetamine causes alterations in the MAP kinase-related pathways in the brains of mice that display increased aggressiveness
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
    Neuropsychopharmacology 31:956-66. 2006
  3. ncbi request reprint Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies?
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD, USA
    Int J Neuropsychopharmacol 10:547-55. 2007
  4. ncbi request reprint Mouse brain gene expression changes after acute and chronic amphetamine
    Boris P Sokolov
    Molecular Neurobiology Branch, NIDA IRP, NIH, Baltimore, Maryland, USA
    J Neurochem 84:244-52. 2003
  5. ncbi request reprint Allele C-specific methylation of the 5-HT2A receptor gene: evidence for correlation with its expression and expression of DNA methylase DNMT1
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, Maryland 21224, USA
    J Neurosci Res 83:362-73. 2006
  6. ncbi request reprint Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    J Neurosci Res 74:111-22. 2003
  7. ncbi request reprint Chronic methamphetamine increases fighting in mice
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 77:319-26. 2004
  8. ncbi request reprint Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
    J Neurosci Res 67:812-22. 2002
  9. ncbi request reprint Microarray analysis of postmortem temporal cortex from patients with schizophrenia
    Christopher Aston
    Neuroscience Discovery Research, Wyeth Research, Princeton, New Jersey, USA
    J Neurosci Res 77:858-66. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, National Institutes of Health, DHHS, Baltimore, Maryland 21224, USA
    J Neurosci Res 72:756-67. 2003
    ..We hypothesize that these mechanisms may be related to alcohol abuse traits or long-term effects of alcohol...
  2. ncbi request reprint Methamphetamine causes alterations in the MAP kinase-related pathways in the brains of mice that display increased aggressiveness
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
    Neuropsychopharmacology 31:956-66. 2006
    ..These findings suggest that alterations in MAP kinase-related pathways in the prefronto-striatal circuitries might be involved in the manifestation of aggressive behaviors in mice...
  3. ncbi request reprint Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies?
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD, USA
    Int J Neuropsychopharmacol 10:547-55. 2007
    ..The possible mechanisms of oligodendroglial abnormalities may involve functional variations in oligodendroglia-related genes, epigenetic regulation of chromatin, DA system hyperactivity and other mechanisms...
  4. ncbi request reprint Mouse brain gene expression changes after acute and chronic amphetamine
    Boris P Sokolov
    Molecular Neurobiology Branch, NIDA IRP, NIH, Baltimore, Maryland, USA
    J Neurochem 84:244-52. 2003
    ..Each of these genes, including transcription factor, cellular regulatory, structural and other gene family members, are candidates to contribute to brain adaptations to psychostimulants...
  5. ncbi request reprint Allele C-specific methylation of the 5-HT2A receptor gene: evidence for correlation with its expression and expression of DNA methylase DNMT1
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, Maryland 21224, USA
    J Neurosci Res 83:362-73. 2006
    ..These findings support the hypothesis that allele-specific DNA methylation is involved in regulation of 5HT2AR expression, influencing expression differences between alleles C and T...
  6. ncbi request reprint Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    J Neurosci Res 74:111-22. 2003
    ..These results suggest that PSZA11q14 may be considered a candidate gene for schizophrenia acting as an antisense regulator of DLG-2, which controls assembling functional N-methyl-D-aspartate (NMDA) receptors...
  7. ncbi request reprint Chronic methamphetamine increases fighting in mice
    Boris P Sokolov
    Molecular Neuropsychiatry Branch, National Institute on Drug Abuse, NIH, DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 77:319-26. 2004
    ..Thus, intermittent administration of METH might be useful as a pharmacological model to study the biochemical and molecular bases of aggressiveness...
  8. ncbi request reprint Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics
    Oxana O Polesskaya
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
    J Neurosci Res 67:812-22. 2002
    ..03). The data suggest that increased prevalence of allele "C" among schizophrenics may be due to intrinsically low expression of this allele, which may contribute to a deficit in 5-HT2AR expression in some schizophrenics...
  9. ncbi request reprint Microarray analysis of postmortem temporal cortex from patients with schizophrenia
    Christopher Aston
    Neuroscience Discovery Research, Wyeth Research, Princeton, New Jersey, USA
    J Neurosci Res 77:858-66. 2004
    ..These findings support the hypothesis that schizophrenia is associated with abnormalities in oligodendroglia and provide initial evidence suggesting a role for epigenetic mechanisms and altered circadian rhythms in this disorder...