Research Topics
| Michael C SnellerSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
A randomized controlled trial of rituximab following failure of antiviral therapy for hepatitis C virus-associated cryoglobulinemic vasculitisMichael C Sneller
Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20854, USA
Arthritis Rheum 64:835-42. 2012..To perform a randomized controlled trial of rituximab in patients with hepatitis C virus (HCV)-associated mixed cryoglobulinemic vasculitis...
Granuloma formation, implications for the pathogenesis of vasculitisMichael C Sneller
Laboratory of Immunoregulation, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Cleve Clin J Med 69:SII40-3. 2002..A better understanding of these events will allow us to more precisely modulate the granulomatous inflammatory response to the benefit of patients with both infectious and autoimmune diseases...
Autoimmune lymphoproliferative syndromeMichael C Sneller
Immunologic Diseases Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Curr Opin Rheumatol 15:417-21. 2003..Prospective evaluations of patients and their families have revealed an ever-expanding spectrum of autoimmune lymphoproliferative syndrome and its major complications...
Mycophenolate mofetil for remission maintenance in the treatment of Wegener's granulomatosisCarol A Langford
National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA
Arthritis Rheum 51:278-83. 2004..To examine the safety of mycophenolate mofetil (MMF) for remission maintenance in patients with Wegener's granulomatosis (WG) who had been treated with daily cyclophosphamide (CYC) and glucocorticoids to induce remission...
CT virtual bronchoscopy of the central airways in patients with Wegener's granulomatosisRonald M Summers
Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892 1182, USA
Chest 121:242-50. 2002..To compare CT virtual bronchoscopy (VB) to CT alone and to conventional bronchoscopy for evaluation of central airway stenoses in patients with Wegener's granulomatosis...
Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaquesThomas A Waldmann
Center for Cancer Research, National Cancer Institute, Frederick, MD, USA
Blood 117:4787-95. 2011....
Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cellsKouhei Yamashita
Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health NIH, Bethesda, MD 20892 1886, USA
Blood 103:3986-8. 2004..This finding implies that overrepresentation of CD4(EM) cells is a unique feature of cGVHD...
Tarsal-conjunctival disease associated with Wegener's granulomatosisMichael R Robinson
National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
Ophthalmology 110:1770-80. 2003..To describe the clinical characteristics of tarsal-conjunctival disease in a cohort of patients with Wegener's granulomatosis (WG)...
B cell homeostasis in chronic hepatitis C virus-related mixed cryoglobulinemia is maintained through naïve B cell apoptosisLauren E Holz
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
Hepatology 56:1602-10. 2012..Conclusion: This study provides insight into the mechanisms maintaining B cell homeostasis in HCV-induced MC and the ability of rituximab therapy to restore normal B cell compartments. (HEPATOLOGY 2012;56:1602-1610)...
Use of a cyclophosphamide-induction methotrexate-maintenance regimen for the treatment of Wegener's granulomatosis: extended follow-up and rate of relapseCarol A Langford
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Med 114:463-9. 2003..To determine the relapse rate and outcome in patients with Wegener's granulomatosis treated with daily cyclophosphamide and glucocorticoids to induce remission followed by methotrexate for remission maintenance...
Pathogenesis of Wegener's granulomatosis: current conceptsPasha Sarraf
Immunologic Diseases Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892 1876, USA
Expert Rev Mol Med 7:1-19. 2005..Future animal models of this disease will have to account for the role of both ANCA-mediated pathology and granulomatous inflammation to enable us to understand the chronic and persistent features of WG in humans...
Biologic therapies in the vasculitidesCarol A Langford
Immunologic Diseases Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Curr Opin Rheumatol 15:3-10. 2003..In the research setting, investigation of biologic agents in the treatment of vasculitic diseases may also provide important insights into pathogenesis of these syndromes...
A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritisGary S Hoffman
Cleveland Clinic Foundation, Cleveland, Ohio 44915, USA
Arthritis Rheum 46:1309-18. 2002....
Rituximab and Wegener's granulomatosis: are B cells a target in vasculitis treatment?Michael C Sneller
Arthritis Rheum 52:1-5. 2005
