Smith G, Medina D. Does the Mouse Mammary Gland Arise from Unipotent or Multipotent Mammary Stem/Progenitor Cells?. J Mammary Gland Biol Neoplasia. 2018;23:1-3 pubmed publisher
..The existence of premalignant mammary populationst that manifest characteristics of lineage limitation argues strongly for this proposition. ..
Smith G, Boulanger C. Mammary stem cell repertoire: new insights in aging epithelial populations. Mech Ageing Dev. 2002;123:1505-19 pubmed
..Our evidence indicates that a single mammary cell may have the capacity to self-renew through five transplant generations. Even some sixth generation implants show vigorous growth. ..
Boulanger C, Rosenfield S, George A, Smith G. Hormone signaling requirements for the conversion of non-mammary mouse cells to mammary cell fate(s) in vivo. J Mammary Gland Biol Neoplasia. 2015;20:93-101 pubmed publisher
Smith G. Binuclear Cells in the Lactating Mammary Gland: New Insights on an Old Concept?. J Mammary Gland Biol Neoplasia. 2016;21:21-3 pubmed publisher
..From a historical perspective, it is more likely that binuclear secretory cells in the lactating mammary gland are a consequence of the DNA synthesis requirement for lactation, rather than an essential element. ..
Smith G. Stem cells and mammary cancer in mice. Stem Cell Rev. 2005;1:215-23 pubmed
..Retroviral marking via MMTV proviral insertion demonstrates that this process progresses from a single mammary epithelial cell that possesses all the features ascribed to tissue-specific stem cells...
Smith G, Medina D. Re-evaluation of mammary stem cell biology based on in vivo transplantation. Breast Cancer Res. 2008;10:203 pubmed publisher
..In the present article, these issues are reviewed and discussed to provide a greater understanding of the complexity of these multiplex interactions...