Research Topics
Species | David L SmithSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: resistance is a regional problemDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 2220, USA
Proc Natl Acad Sci U S A 101:3709-14. 2004..To successfully manage ARB at tertiary-care hospitals, regional coordination of infection control may be necessary, including tracking asymptomatic carriers through health-care systems...
Revisiting the basic reproductive number for malaria and its implications for malaria controlDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS Biol 5:e42. 2007..Therefore, strategic planning for malaria control should consider R0, the spatial scale of transmission, human population density, and heterogeneous biting...
Strategic interactions in multi-institutional epidemics of antibiotic resistanceDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 2220, USA
Proc Natl Acad Sci U S A 102:3153-8. 2005..We conclude that regional coordination and planning for HIC is an essential element of public health planning for hospital-acquired infections...
Agricultural antibiotics and human healthDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS Med 2:e232. 2005
Assessing the role of long-distance translocation and spatial heterogeneity in the raccoon rabies epidemic in ConnecticutD L Smith
Fogarty International Center, Bethesda, MD 20892, USA
Prev Vet Med 71:225-40. 2005..LDT events are a concern, but this analysis suggests that at a local scale they can be isolated and managed...
The entomological inoculation rate and Plasmodium falciparum infection in African childrenD L Smith
Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
Nature 438:492-5. 2005..The results have important implications for public health interventions: the success of malaria control will depend heavily on whether efforts are targeted at those who are most at risk of infection...
An elaborated feeding cycle model for reductions in vectorial capacity of night-biting mosquitoes by insecticide-treated netsArnaud Le Menach
Universite Pierre et Marie Curie Paris 6, UMR S 707, Paris, France
Malar J 6:10. 2007..Insecticide Treated Nets (ITNs) are an important tool for malaria control. ITNs are effective because they work on several parts of the mosquito feeding cycle, including both adult killing and repelling effects...
Statics and dynamics of malaria infection in Anopheles mosquitoesDavid L Smith
Building 16, Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Malar J 3:13. 2004..The classic formulae are used to to illustrate how malaria control reduces malaria transmission and show that increased mosquito mortality has an effect even larger than was proposed by Macdonald in the 1950's...
A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDaShannon L Takala
Center for Vaccine Development, University of Maryland School of Medicine, HSF1 480, Baltimore, Maryland 21201, USA
Malar J 5:31. 2006..Methods are needed to monitor genetic diversity in polymorphic vaccine antigens, but determining which genetic variants of such antigens are present in infected individuals is complicated by the frequent occurrence of mixed infections...
Gametocytemia in Plasmodium vivax and Plasmodium falciparum infectionsF Ellis McKenzie
Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Parasitol 92:1281-5. 2006..falciparum patients with gametocytemia had similar platelet counts but lower red blood cell counts, hemoglobin levels, hematocrit levels, and higher lymphocyte counts than patients without gametocytemia...
Projected benefits of active surveillance for vancomycin-resistant enterococci in intensive care unitsEli N Perencevich
Veterans Affairs Maryland Healthcare System, Baltimore, Maryland, USA
Clin Infect Dis 38:1108-15. 2004..Passive surveillance was minimally effective. Using the best available data, active surveillance is projected to be effective for reducing VRE transmission in ICU settings...
Standardizing estimates of the Plasmodium falciparum parasite rateDavid L Smith
Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
Malar J 6:131. 2007..This confounds simple comparisons of PfPR surveys conducted at different times or places...
The unexpected importance of mosquito oviposition behaviour for malaria: non-productive larval habitats can be sources for malaria transmissionArnaud Le Menach
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Malar J 4:23. 2005..One of the possible strategies of malaria control is to identify local vector species and then attack water bodies that contain their larvae...
Strain theory of malaria: the first 50 yearsF Ellis McKenzie
Fogarty International Center, Building 16, National Institutes of Health, Bethesda, Maryland 20892, USA
Adv Parasitol 66:1-46. 2008..Here we review the search for a definition of 'strain', suggest how the data and discussion shaped current understandings of many aspects of malaria and sketch a number of specific connections with perspectives from the past 30 years...
Ross, macdonald, and a theory for the dynamics and control of mosquito-transmitted pathogensDavid L Smith
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS Pathog 8:e1002588. 2012..The Ross-Macdonald theory has since played a central role in development of research on mosquito-borne pathogen transmission and the development of strategies for mosquito-borne disease prevention...
The risk of a mosquito-borne infection in a heterogeneous environmentDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS Biol 2:e368. 2004..Finally, we show that estimates for the average risk of infection that are based on the average entomological inoculation rate are strongly biased in heterogeneous environments...
Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populationsSaranath Lawpoolsri
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
Malar J 8:159. 2009....
Fever in patients with mixed-species malariaF Ellis McKenzie
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Clin Infect Dis 42:1713-8. 2006..Clinical symptoms of mixed-species malaria infections have been variously reported as both less severe and more severe than those of single-species infections...
Synchrony, waves, and spatial hierarchies in the spread of influenzaCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Science 312:447-51. 2006..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints...
Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malariaWendy Prudhomme O'Meara
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS Med 3:e141. 2006....
Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in MaliShannon L Takala
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
PLoS Med 4:e93. 2007....
Superinfection and the evolution of resistance to antimalarial drugsEili Y Klein
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
Proc Biol Sci 279:3834-42. 2012..Considering superinfection in mathematical models of antimalarial drug resistance may thus be important for generating accurate predictions of interventions to contain resistance...
The complete management of extremity vascular injury in a local population: a wartime report from the 332nd Expeditionary Medical Group/Air Force Theater Hospital, Balad Air Base, IraqMichael A Peck
332nd Air Force Theater Hospital AFTH, Balad, Iraq, and Norman M Rich Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
J Vasc Surg 45:1197-204; discussion 1204-5. 2007..This study reports the complete management of extremity vascular injury in a local wartime population and illustrates the unique aspects of this cohort and management strategy...
Geographical distribution and risk factors associated with enteric diseases in VietnamLouise A Kelly-Hope
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Trop Med Hyg 76:706-12. 2007..The distinct geographical patterns of each disease appear to be driven by a combination of different ecological factors...
Hyperinfectivity: a critical element in the ability of V. cholerae to cause epidemics?David M Hartley
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
PLoS Med 3:e7. 2006..However, cholera models that have been developed to date have had limitations, suggesting that there are basic elements of cholera transmission that we still do not understand...
