Rashmi Sinha

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in India
    Rashmi Sinha
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    BMC Public Health 11:405. 2011
  2. pmc Dietary meat intake in relation to colorectal adenoma in asymptomatic women
    Leah M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Gastroenterol 104:1231-40. 2009
  3. pmc A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risks
    Natasa Tasevska
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
    Am J Clin Nutr 89:1884-94. 2009
  4. pmc Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Clin Nutr 97:1036-43. 2013
  5. pmc Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 96:374-81. 2012
  6. pmc Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1465-75. 2011
  7. pmc Meat consumption and risk of esophageal and gastric cancer in a large prospective study
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Am J Gastroenterol 106:432-42. 2011
  8. pmc Pancreatic cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health Study
    Briseis Aschebrook-Kilfoy
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Am J Epidemiol 174:305-15. 2011
  9. pmc A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association
    Amanda J Cross
    Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
    Cancer Res 70:2406-14. 2010
  10. ncbi request reprint Meat, meat cooking methods and preservation, and risk for colorectal adenoma
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 65:8034-41. 2005

Detail Information

Publications70

  1. pmc Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in India
    Rashmi Sinha
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    BMC Public Health 11:405. 2011
    ..The aim of this feasibility study was to evaluate whether a diet-focused cohort study of cancer could be established in India, providing insight into potentially unique diet and lifestyle exposures...
  2. pmc Dietary meat intake in relation to colorectal adenoma in asymptomatic women
    Leah M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Gastroenterol 104:1231-40. 2009
    ....
  3. pmc A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risks
    Natasa Tasevska
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
    Am J Clin Nutr 89:1884-94. 2009
    ..Red and processed meat consumption may play a role in lung cancer pathogenesis because of these meats' fat and carcinogen content...
  4. pmc Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Clin Nutr 97:1036-43. 2013
    ..Diet may play a role in the etiology of RCC directly and/or indirectly...
  5. pmc Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 96:374-81. 2012
    ..Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites...
  6. pmc Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1465-75. 2011
    ....
  7. pmc Meat consumption and risk of esophageal and gastric cancer in a large prospective study
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Am J Gastroenterol 106:432-42. 2011
    ..Although there have been multiple studies of meat and colorectal cancer, other gastrointestinal malignancies are understudied...
  8. pmc Pancreatic cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health Study
    Briseis Aschebrook-Kilfoy
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Am J Epidemiol 174:305-15. 2011
    ..These results provide modest evidence that processed meat sources of dietary nitrate and nitrite may be associated with pancreatic cancer among men and provide no support for the hypothesis in women...
  9. pmc A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association
    Amanda J Cross
    Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
    Cancer Res 70:2406-14. 2010
    ..In conclusion, we found a positive association for red and processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from meat may explain these associations...
  10. ncbi request reprint Meat, meat cooking methods and preservation, and risk for colorectal adenoma
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 65:8034-41. 2005
    ..04; 95% CI, 0.90-1.19). Our study of screening-detected colorectal adenomas shows that red meat and meat cooked at high temperatures are associated with an increased risk of colorectal adenoma...
  11. pmc A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in India
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Nutr J 10:12. 2011
    ..The role of diet in India's rapidly progressing chronic disease epidemic is unclear; moreover, diet may vary considerably across North-South regions...
  12. pmc Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohort
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Rockville, MD 20852, USA
    J Natl Cancer Inst 102:1354-65. 2010
    ..Several plausible mechanisms, including fat, iron, heterocyclic amines, and N-nitroso compounds, link meat intake with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Few studies have investigated these associations...
  13. pmc Socioeconomic deprivation impact on meat intake and mortality: NIH-AARP Diet and Health Study
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Causes Control 22:1699-707. 2011
    ..This study examined the impact of area socioeconomic deprivation on the association between meat intake and all-cause and cause-specific mortality after accounting for individual-level risk factors...
  14. pmc Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 69:1877-84. 2009
    ..The observed effect provides evidence to support the hypothesis that HCAs may act as promoters of malignant transformation by altering mitogenic signaling...
  15. ncbi request reprint Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 28:1426-9. 2007
    ..8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. These data support a link between PAH exposure and colorectal adenoma...
  16. pmc Meat intake is not associated with risk of non-Hodgkin lymphoma in a large prospective cohort of U.S. men and women
    Carrie R Daniel
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    J Nutr 142:1074-80. 2012
    ..In this large U.S. cohort, meat intake was not associated with NHL or any histologic subtypes of NHL. Contrary to findings in animal models and other cancer sites, meat-cooking and -processing compounds did not increase NHL risk...
  17. pmc Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 95:155-62. 2012
    ..The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent. Mutagens related to meat cooking and processing, and variation by RCC subtype may be important to consider...
  18. pmc Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United States
    Rashmi Sinha
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Am J Epidemiol 170:1165-77. 2009
    ..There were no clear associations for fatal prostate cancer. Red and processed meat may be positively associated with prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and benzo[a]pyrene...
  19. pmc Meat-related compounds and colorectal cancer risk by anatomical subsite
    Paige E Miller
    Cancer Prevention Fellowship Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nutr Cancer 65:202-26. 2013
    ..05). HCAs, PAHs, nitrites, and nitrates may be involved in colorectal cancer etiology. Further examination into the unexpected inverse associations between poultry and colorectal cancer is warranted...
  20. pmc Socioeconomic status, healthcare density, and risk of prostate cancer among African American and Caucasian men in a large prospective study
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA
    Cancer Causes Control 23:1185-91. 2012
    ..The purpose of this study was to separately examine the impact of neighborhood socioeconomic deprivation and availability of healthcare resources on prostate cancer risk among African American and Caucasian men...
  21. pmc Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach
    Mary H Ward
    Department of Health and Human Services, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Eur J Cancer Prev 21:134-8. 2012
    ..Our results suggest that high intakes of heme and iron from meat may be important dietary risk factors for esophageal and stomach cancer and may partly explain associations with red meat...
  22. pmc Epithelial ovarian cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health Study
    Briseis Aschebrook-Kilfoy
    Occupational and Environmental Epidemiology Branch, DCEG, NCI, NIH, Rockville, Maryland 20852, USA
    Eur J Cancer Prev 21:65-72. 2012
    ..There were no clear differences in risk by histologic subtype of ovarian cancer. Our findings suggest that a role of dietary nitrate and nitrite in ovarian cancer risk should be followed in other large cohort studies...
  23. pmc Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk
    Tram Kim Lam
    Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, NIH, Department of Health and Human Services, corrected Bethesda, Maryland 20892 7236, USA
    Cancer Res 69:932-9. 2009
    ..In summary, red meat, processed meat, and meat mutagens were independently associated with increased risk of lung cancer...
  24. ncbi request reprint Urinary mutagenesis and fried red meat intake: influence of cooking temperature, phenotype, and genotype of metabolizing enzymes in a controlled feeding study
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7273, USA
    Environ Mol Mutagen 43:53-74. 2004
    ..The data from this study indicate that urinary mutagenicity correlates with mutagenic exposure from cooked meat and can potentially be used as a marker in etiological studies on cancer...
  25. pmc Meat and components of meat and the risk of bladder cancer in the NIH-AARP Diet and Health Study
    Leah M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer 116:4345-53. 2010
    ..The authors comprehensively investigated the association between meat and meat components and bladder cancer...
  26. pmc Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women
    Unhee Lim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
    Gastroenterology 134:47-55. 2008
    ..We examined genomic methylation of leukocyte DNA in relation to colorectal adenoma (CRA) among asymptomatic women (40-79 years of age) participating in a multicenter colonoscopy screening study (CONCeRN Study, 2000-2002)...
  27. pmc Common genetic variants and central adiposity among Asian-Indians
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Obesity (Silver Spring) 20:1902-8. 2012
    ....
  28. pmc Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer
    Anne M J Gilsing
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services Bethesda, MD, USA
    Carcinogenesis 33:1332-9. 2012
    ..This large and comprehensive study of XME genes, meat mutagens and the risk of colorectal tumours found that a NAT1 polymorphism modified the association between MeIQx intake and colorectal adenoma risk...
  29. pmc A prospective study of red and processed meat intake in relation to cancer risk
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
    PLoS Med 4:e325. 2007
    ..We investigated whether red or processed meat intake increases cancer risk at a variety of sites...
  30. pmc Neighborhood socioeconomic deprivation and mortality: NIH-AARP diet and health study
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 5:e15538. 2010
    ....
  31. pmc Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 17:80-7. 2008
    ..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
  32. pmc No effect of meat, meat cooking preferences, meat mutagens or heme iron on lung cancer risk in the prostate, lung, colorectal and ovarian cancer screening trial
    Natasa Tasevska
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 128:402-11. 2011
    ..In this population, we found no association between meat type, cooking method, doneness level or intake of specific meat mutagens or heme iron and lung cancer risk...
  33. pmc Prospective investigation of poultry and fish intake in relation to cancer risk
    Carrie R Daniel
    Nutritional Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Blvd, Suite 320, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1903-11. 2011
    ..Simply increasing fish or poultry intake, without reducing red meat intake, may be less beneficial for cancer prevention...
  34. pmc Patterns of meat intake and risk of prostate cancer among African-Americans in a large prospective study
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Causes Control 22:1691-8. 2011
    ..The purpose of this study was to examine the association between type of meat intake and prostate cancer risk among African-American men...
  35. ncbi request reprint Meat-related mutagens/carcinogens in the etiology of colorectal cancer
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Environ Mol Mutagen 44:44-55. 2004
    ..Here, we review the current epidemiologic knowledge of meat-related mutagens, and evaluate the types of studies that may be required in the future to clarify the association between meat consumption and colorectal cancer...
  36. ncbi request reprint Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohort
    Rachael Z Stolzenberg-Solomon
    National Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health Human Services, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 16:2664-75. 2007
    ..006) increased risk in men and women combined. These findings support the hypothesis that meat intake, particularly meat cooked at high temperatures and associated mutagens, may play a role in pancreatic cancer development...
  37. ncbi request reprint Dietary benzo[a]pyrene intake and risk of colorectal adenoma
    Rashmi Sinha
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    Cancer Epidemiol Biomarkers Prev 14:2030-4. 2005
    ..21 (1.79-9.91) for the third quintile, 2.45 (0.98-6.12) for the fourth quintile, and 5.60 (2.20-14.20) for the fifth quintile (Ptrend=0.002). This study provides evidence that dietary BaP plays a role in colorectal adenoma etiology...
  38. ncbi request reprint A prospective study of meat and meat mutagens and prostate cancer risk
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Res 65:11779-84. 2005
    ..01-1.61). In conclusion, very well done meat was positively associated with prostate cancer risk. In addition, this study lends epidemiologic support to the animal studies, which have implicated PhIP as a prostate carcinogen...
  39. pmc Association of coffee drinking with total and cause-specific mortality
    Neal D Freedman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    N Engl J Med 366:1891-904. 2012
    ..Coffee is one of the most widely consumed beverages, but the association between coffee consumption and the risk of death remains unclear...
  40. ncbi request reprint Urinary mutagenicity and colorectal adenoma risk
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 7273, USA
    Cancer Epidemiol Biomarkers Prev 12:1253-6. 2003
    ..2-13.9, comparing the highest with the lowest quintile). In our study population, diet may have contributed to mutagenic exposure, which was positively associated with colorectal adenoma risk...
  41. ncbi request reprint Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Carcinogenesis 26:637-42. 2005
    ..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis...
  42. ncbi request reprint Fat, fiber, fruits, vegetables, and risk of colorectal adenomas
    Aleyamma Mathew
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Int J Cancer 108:287-92. 2004
    ..This is likely to be an indicator of "unhealthy" food (meat, dairy, margarine, mayonnaise, sweet baked food) consumption in this population. Increased intake of dietary fiber was associated with a moderately decreased risk of adenomas...
  43. pmc Measurement of spices and seasonings in India: opportunities for cancer epidemiology and prevention
    Leah M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Asian Pac J Cancer Prev 11:1621-9. 2010
    ....
  44. ncbi request reprint Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control study
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
    Carcinogenesis 27:293-7. 2006
    ..39 (0.22-0.70); P trend = 0.004]. Overall, our study suggests that consumption of meat, whether or not it is well-done, does not increase the risk of NHL. Furthermore, neither HCAs nor B[a]P from meat increase the risk of NHL...
  45. ncbi request reprint Processed meat intake, CYP2A6 activity and risk of colorectal adenoma
    Mary H Ward
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Carcinogenesis 28:1210-6. 2007
    ..Our results suggest that nitrite and nitrate intake from processed meat intake increases the risk of colorectal adenoma after accounting for HCA and PAH...
  46. pmc Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP)
    Nicole C Deziel
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, USA
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 29:1202-11. 2012
    ..Improved HCA assessment tools, such as a combination of methods or validated biomarkers that capture long term exposure, are needed...
  47. ncbi request reprint Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Int J Cancer 118:3147-52. 2006
    ..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk...
  48. pmc Meat intake and mortality: a prospective study of over half a million people
    Rashmi Sinha
    Division of Cancer Epidemiology and Genetics, National Cancer Institute Nutritional Epidemiology Branch, Rockville, MD 20852, USA
    Arch Intern Med 169:562-71. 2009
    ..High intakes of red or processed meat may increase the risk of mortality. Our objective was to determine the relations of red, white, and processed meat intakes to risk for total and cause-specific mortality...
  49. ncbi request reprint A prospective study of serum C-reactive protein and colorectal cancer risk in men
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 66:2483-7. 2006
    ..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
  50. doi request reprint Development of a field-friendly automated dietary assessment tool and nutrient database for India
    Carrie R Daniel
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Suite 320, Rockville, MD 20852, USA
    Br J Nutr 111:160-71. 2014
    ....
  51. ncbi request reprint Inflammation-related gene polymorphisms and colorectal adenoma
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:1126-31. 2006
    ..7; 95% CI, 0.3-1.5; P(interaction) = 0.01). These exploratory data provide evidence that polymorphic variation in genes that regulate inflammation could alter risk for colorectal adenoma...
  52. pmc Urinary biomarkers of meat consumption
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:1107-11. 2011
    ..One method to circumvent such errors is the use of biomarkers of dietary intake, but currently there are no accepted biomarkers for meat intake...
  53. pmc Trends in meat consumption in the USA
    Carrie R Daniel
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Public Health Nutr 14:575-83. 2011
    ..To characterize the trends, distribution, potential determinants and public health implications of meat consumption within the USA...
  54. pmc Soluble receptor for advanced glycation end products and risk of liver cancer
    Kristin A Moy
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hepatology 57:2338-45. 2013
    ..Conclusion: Our results support the hypothesis that sRAGE is inversely associated with liver cancer. The findings need confirmation, particularly in populations that include women and nonsmokers. (HEPATOLOGY 2013 )...
  55. ncbi request reprint Relative validity of a food frequency questionnaire with a meat-cooking and heterocyclic amine module
    Marie Cantwell
    Nutrition Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Cancer Epidemiol Biomarkers Prev 13:293-8. 2004
    ..In conclusion, although the FFQ and meat module underestimated absolute MeIQx and PhIP intake, its ability to rank individuals according to intake was acceptable...
  56. ncbi request reprint Development of a food frequency questionnaire module and databases for compounds in cooked and processed meats
    Rashmi Sinha
    Nutrition Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7273, USA
    Mol Nutr Food Res 49:648-55. 2005
    ....
  57. pmc Coffee consumption is associated with response to peginterferon and ribavirin therapy in patients with chronic hepatitis C
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Gastroenterology 140:1961-9. 2011
    ..However, its relationship with therapy for hepatitis C virus infection has not been evaluated...
  58. ncbi request reprint Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and US
    Tanuja Rastogi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Int J Epidemiol 37:147-60. 2008
    ..Examining such rates may provide us with insights into future aetiological research possibilities as well as screening and prevention...
  59. doi request reprint Testing multiple biological mediators simultaneously
    Simina M Boca
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Bioinformatics 30:214-20. 2014
    ....
  60. pmc Metabolomics in epidemiology: sources of variability in metabolite measurements and implications
    Joshua N Sampson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 22:631-40. 2013
    ..Here, the authors assess the variability of a large subset of metabolites and evaluate the implications for epidemiologic studies...
  61. ncbi request reprint Meat, fat, and their subtypes as risk factors for colorectal cancer in a prospective cohort of women
    Andrew Flood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 158:59-68. 2003
    ..This study provided no evidence of an association between either meat or fat (or any of their subtypes) and colorectal cancer incidence, but the authors cannot rule out the possibility of a modest association...
  62. ncbi request reprint A correlation study of organochlorine levels in serum, breast adipose tissue, and gluteal adipose tissue among breast cancer cases in India
    Jennifer A Rusiecki
    Occupational and Environmental Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Bethesda, MD 20892 7240, USA
    Cancer Epidemiol Biomarkers Prev 14:1113-24. 2005
    ..However, such measurements are a combination of both recent exposures and past exposures, which have metabolized slowly and may still persist. Therefore, investigators should use caution when assigning a level as lifetime body burden...
  63. ncbi request reprint Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas
    Naoko Ishibe
    Genetic Epidemioly Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
    Pharmacogenetics 12:145-50. 2002
    ..Further study of larger populations is needed to confirm and extend these observations...
  64. pmc Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Hepatology 50:1360-9. 2009
    ..47 (0.27-0.85) for 3 or more cups/day (P-trend = 0.0003) versus not drinking. Risk estimates did not vary by treatment assignment or cirrhosis status at baseline. Tea intake was not associated with outcomes...
  65. pmc Human gut microbiome and risk for colorectal cancer
    Jiyoung Ahn
    Affiliations of authors Division of Epidemiology, Department of Population Health JA, CD, JW, RBH, Department of Pathology ZP, and Department of Medicine ZP, ly, New York University School of Medicine, New York, NY New York University Cancer Institute, New York, NY JA, ZP, CD, JW, RBH Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD RS, JS, JJG Department of Pathology and Laboratory Medicine, New York Veterans Affairs Medical Center, New York, NY ZP
    J Natl Cancer Inst 105:1907-11. 2013
    ..17; 95% CI = 1.75 to 15.25) were found in case subjects compared with control subjects. Because of the potentially modifiable nature of the gut bacteria, our findings may have implications for CRC prevention. ..
  66. ncbi request reprint An epidemiologic approach to studying heterocyclic amines
    Rashmi Sinha
    Nutritional Epidemiology Branch, Rm 7028, National Cancer Institute, 6120 Executive Boulevard, EPS 3024, Rockville, MD 20892, USA
    Mutat Res 506:197-204. 2002
    ..In this manuscript I will provide one approach to studying the relation of meat cooking-mutagens and cancer risk and will suggest the types of studies that may be required in the future to clarify these associations...
  67. ncbi request reprint Opportunities for cancer epidemiology in developing countries
    Tanuja Rastogi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, Maryland 20852, USA
    Nat Rev Cancer 4:909-17. 2004
    ..What are the challenges and advantages to performing large epidemiological studies in developing nations?..
  68. ncbi request reprint Highly sensitive chemiluminescence immunoassay for benzo[a]pyrene-DNA adducts: validation by comparison with other methods, and use in human biomonitoring
    Rao L Divi
    National Cancer Institute, NIH, Bethesda, MD 20892 4255, USA
    Carcinogenesis 23:2043-9. 2002
    ..95). Coded duplicate DNA samples from 15 individuals were assayed four times gave an inter-assay CV of 13.8%...
  69. ncbi request reprint Highlights of the eighth international conference on carcinogenic/mutagenic N-substituted aryl compounds
    Elizabeth G Snyderwine
    Chemical Carcinogenesis Section, Laboratory of Experimental Carcinogenesis, National Cancer Institute, Bethesda, MD 20892 4258, USA
    Mutat Res 506:1-8. 2002
    ....
  70. ncbi request reprint Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme
    Ulrike Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, DHHS, MD 20892 7273, USA
    Lancet 361:1491-5. 2003
    ..Although dietary fibre has been reported to have no association with colorectal adenoma and cancer, in some studies this topic remains controversial...