Rajesh K Sinha

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institute of Heath, Building 10, Room 11N311, 10 Center Drive, MSC 1892, Bethesda, MD 20892, USA
    Dev Comp Immunol 28:829-41. 2004
  2. pmc De novo expression of MECA-79 glycoprotein-determinant on developing B lymphocytes in gut-associated lymphoid tissues
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Immunology 119:461-9. 2006
  3. ncbi request reprint Regulated expression of peripheral node addressin-positive high endothelial venules controls seeding of B lymphocytes into developing neonatal rabbit appendix
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N311, 10 Center Drive MSC 1892, Bethesda, MD 20892, USA
    Vet Immunol Immunopathol 110:97-108. 2006
  4. ncbi request reprint CD5+ B cells are preferentially expanded in rabbit appendix: the role of CD5 in B cell development and selection
    Richard Pospisil
    Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892 1892, USA
    Dev Comp Immunol 30:711-22. 2006
  5. pmc Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization
    Chung Park
    B Cell Molecular Immunology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Blood 119:978-89. 2012
  6. pmc Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix
    Guibin Yang
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and SAIC Frederick, National Cancer Institute, Frederick, MD 21701, USA
    Proc Natl Acad Sci U S A 102:17083-8. 2005
  7. pmc B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis
    Rajesh K Sinha
    B Cell Molecular Immunology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Disease, Bethesda, MD 20892 1876, USA
    Immunity 30:434-46. 2009

Collaborators

  • Rose G Mage
  • John H Kehrl
  • Chung Park
  • Richard Pospisil
  • Harold Obiakor
  • Guibin Yang
  • Il Young Hwang
  • Olena Kamenyeva
  • Michael D Davis
  • Cornelius B Alexander
  • Brian L Hood
  • Thomas P Conrads
  • Timothy D Veenstra
  • Barbara A Newman

Detail Information

Publications7

  1. ncbi request reprint Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institute of Heath, Building 10, Room 11N311, 10 Center Drive, MSC 1892, Bethesda, MD 20892, USA
    Dev Comp Immunol 28:829-41. 2004
    ..The cross-reactivity of antibodies to mouse or human adhesion molecules described in this study indicates that some of the structures of these important molecules are conserved across species...
  2. pmc De novo expression of MECA-79 glycoprotein-determinant on developing B lymphocytes in gut-associated lymphoid tissues
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Immunology 119:461-9. 2006
    ....
  3. ncbi request reprint Regulated expression of peripheral node addressin-positive high endothelial venules controls seeding of B lymphocytes into developing neonatal rabbit appendix
    Rajesh K Sinha
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N311, 10 Center Drive MSC 1892, Bethesda, MD 20892, USA
    Vet Immunol Immunopathol 110:97-108. 2006
    ..Thus, a unique spatiotemporal expression pattern of PNAd(+) HEVs is associated with development of B-cell follicles. This regulates migration of blood-borne B-lymphocytes into developing appendix by interacting with CD62L...
  4. ncbi request reprint CD5+ B cells are preferentially expanded in rabbit appendix: the role of CD5 in B cell development and selection
    Richard Pospisil
    Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892 1892, USA
    Dev Comp Immunol 30:711-22. 2006
    ....
  5. pmc Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization
    Chung Park
    B Cell Molecular Immunology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Blood 119:978-89. 2012
    ..These results are summarized in a model of homeostatic trafficking of B cells through LNs...
  6. pmc Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix
    Guibin Yang
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and SAIC Frederick, National Cancer Institute, Frederick, MD 21701, USA
    Proc Natl Acad Sci U S A 102:17083-8. 2005
    ..Although much work remains to understand fully the mechanism of action of AID and its association with other cellular components, the rabbit system now offers a particularly useful model for future studies of these dynamics...
  7. pmc B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis
    Rajesh K Sinha
    B Cell Molecular Immunology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Disease, Bethesda, MD 20892 1876, USA
    Immunity 30:434-46. 2009
    ..This study identifies a major site of B lymphocyte lymph node egress, shows that FTY720 treatment blocks passage through the cortical lymphatic endothelium, and argues against a functional role for S1P chemotaxis in B lymphocyte egress...