Research Topics
Species | R SinhaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Parent-child correlation for various indices of adiposity in an endogamous Indian populationRashmi Sinha
Department of Anthropology, University of Delhi, India
Coll Antropol 30:291-6. 2006..The correlations were of low magnitude, however, some skin folds displayed relatively higher value of correlation indicating that these could be determinant of adult obesity...
Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective studyRashmi Sinha
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 96:374-81. 2012..Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites...- Development of a food frequency questionnaire module and databases for compounds in cooked and processed meatsRashmi Sinha
Nutrition Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7273, USA
Mol Nutr Food Res 49:648-55. 2005.... - Dietary benzo[a]pyrene intake and risk of colorectal adenomaRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
Cancer Epidemiol Biomarkers Prev 14:2030-4. 2005..21 (1.79-9.91) for the third quintile, 2.45 (0.98-6.12) for the fourth quintile, and 5.60 (2.20-14.20) for the fifth quintile (Ptrend=0.002). This study provides evidence that dietary BaP plays a role in colorectal adenoma etiology... - An epidemiologic approach to studying heterocyclic aminesRashmi Sinha
Nutritional Epidemiology Branch, Rm 7028, National Cancer Institute, 6120 Executive Boulevard, EPS 3024, Rockville, MD 20892, USA
Mutat Res 506:197-204. 2002..In this manuscript I will provide one approach to studying the relation of meat cooking-mutagens and cancer risk and will suggest the types of studies that may be required in the future to clarify these associations... - Meat intake and mortality: a prospective study of over half a million peopleRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute Nutritional Epidemiology Branch, Rockville, MD 20852, USA
Arch Intern Med 169:562-71. 2009..High intakes of red or processed meat may increase the risk of mortality. Our objective was to determine the relations of red, white, and processed meat intakes to risk for total and cause-specific mortality... - Meat, meat cooking methods and preservation, and risk for colorectal adenomaRashmi Sinha
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Res 65:8034-41. 2005..04; 95% CI, 0.90-1.19). Our study of screening-detected colorectal adenomas shows that red meat and meat cooked at high temperatures are associated with an increased risk of colorectal adenoma... - Dietary heterocyclic amines and the risk of lung cancer among Missouri womenR Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Res 60:3753-6. 2000..Neither DiMeIQx nor PhIP showed an association with smoking categories or lung cancer histology. In conclusion, MeIQx may be associated with lung cancer risk, but DiMeIQx and PhIP are probably not associated with lung cancer risk... - Role of well-done, grilled red meat, heterocyclic amines (HCAs) in the etiology of human cancerR Sinha
Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD 20892 7374, USA
Cancer Lett 143:189-94. 1999..Furthermore, the use of these exposure assessment approaches are being used in large prospective studies world wide and should help clarify the role of doneness, cooking practices and pyrolysis products in the etiology of human cancer... - Cancer risk and diet in IndiaR Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892 7273, USA
J Postgrad Med 49:222-8. 2003..From a public health perspective, there is an increasing need to develop cancer prevention programs responsive to the unique diets and cultural practices of the people of India... - Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomasR Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 10:559-62. 2001.... - Dietary intake of nitrate and nitrite and risk of renal cell carcinoma in the NIH-AARP Diet and Health StudyC T Dellavalle
Department of Health and Human Services, Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, NIH DHHS, 6120 Executive Boulevard, EPS 8011, Bethesda, Rockville, MD 20892, USA
Br J Cancer 108:205-12. 2013.... - Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studiesR Sinha
Division of Cancer Epidemiology and Genetics, NCI, Bethesda, MD 20892 7374, USA
Mutat Res 376:195-202. 1997..These studies should help clarify the role of HCAs in human carcinogenesis, and eventually allow an estimation of the cancer burden in the population attributable to these compounds... - Lung cancer risk and red meat consumption among Iowa womenM C Alavanja
Division of Cancer Epidemiology and Genetics, NCI, National Institutes of Health, 6120 Executive Boulevard EPS, Room 8000, Bethesda, MD 20892, USA
Lung Cancer 34:37-46. 2001..In Iowa, we had the opportunity to investigate concurrently the role of meat intake and macronutrients in lung cancer etiology... - Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialL M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Br J Cancer 101:178-84. 2009..We investigated meat subtypes, cooking practices, meat mutagens, iron, and subsequent breast cancer risk... - Meat cooking and cancer riskR Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Executive Plaza North, Rm. 443, 6130 Executive Blvd, Rockville, MD 20892, USA
IARC Sci Publ 156:181-6. 2002 - Intakes of red meat, processed meat, and meat mutagens increase lung cancer riskTram Kim Lam
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, NIH, Department of Health and Human Services, corrected Bethesda, Maryland 20892 7236, USA
Cancer Res 69:932-9. 2009..In summary, red meat, processed meat, and meat mutagens were independently associated with increased risk of lung cancer... - Meat consumption and the risk of incident distal colon and rectal adenomaL M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Br J Cancer 106:608-16. 2012..Most studies of meat and colorectal adenoma have investigated prevalent events from a single screening, thus limiting our understanding of the role of meat and meat-related exposures in early colorectal carcinogenesis... - Heterocyclic amines, meat intake, and association with colon cancer in a population-based studyL M Butler
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Am J Epidemiol 157:434-45. 2003..0. Overall, sophisticated exposure measures were used to report modest, positive associations between red meat intake and colon cancer consistent with the hypothesis that HCAs may be among the etiologically relevant compounds in red meat... - Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic studyN Kazerouni
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892, USA
Food Chem Toxicol 39:423-36. 2001..This database may be helpful in initial attempts to assess dietary BaP exposures in studies of cancer etiology... - Fat, fiber, fruits, vegetables, and risk of colorectal adenomasAleyamma Mathew
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Int J Cancer 108:287-92. 2004..Increased intake of dietary fiber was associated with a moderately decreased risk of adenomas... - Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United StatesRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Am J Epidemiol 170:1165-77. 2009..There were no clear associations for fatal prostate cancer. Red and processed meat may be positively associated with prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and benzo[a]pyrene... - Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD 20852, USA
Carcinogenesis 28:1426-9. 2007..8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. These data support a link between PAH exposure and colorectal adenoma... - Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic womenUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
Gastroenterology 134:47-55. 2008..We examined genomic methylation of leukocyte DNA in relation to colorectal adenoma (CRA) among asymptomatic women (40-79 years of age) participating in a multicenter colonoscopy screening study (CONCeRN Study, 2000-2002)... - Dietary intake of meat, fruits, vegetables, and selective micronutrients and risk of bladder cancer in the New England region of the United StatesJ W Wu
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, Rockville, MD 20852, USA
Br J Cancer 106:1891-8. 2012..Despite many studies on diet and bladder cancer, there are areas that remain unexplored including meat mutagens, specific vegetable groups, and vitamins from diet... - Meat-cooking mutagens and risk of renal cell carcinomaC R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Rockville, MD 20852, USA
Br J Cancer 105:1096-104. 2011.... - Meat intake and the recurrence of colorectal adenomasA Mathew
Nutritional Epidemiology Branch, Division of Epidemiologya nd Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Eur J Cancer Prev 13:159-64. 2004.... - Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trialN D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Aliment Pharmacol Ther 33:127-37. 2011..Silymarin is the most commonly used herbal product for chronic liver disease; yet, whether silymarin protects against liver disease progression remains unclear... - Meat and meat mutagens and risk of prostate cancer in the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:80-7. 2008..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort... - A prospective study of red and processed meat intake in relation to cancer riskAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
PLoS Med 4:e325. 2007..We investigated whether red or processed meat intake increases cancer risk at a variety of sites... - Inflammation-related gene polymorphisms and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 15:1126-31. 2006..7; 95% CI, 0.3-1.5; P(interaction) = 0.01). These exploratory data provide evidence that polymorphic variation in genes that regulate inflammation could alter risk for colorectal adenoma... - Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohortRachael Z Stolzenberg-Solomon
National Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health Human Services, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 16:2664-75. 2007..006) increased risk in men and women combined. These findings support the hypothesis that meat intake, particularly meat cooked at high temperatures and associated mutagens, may play a role in pancreatic cancer development... - Processed meat intake, CYP2A6 activity and risk of colorectal adenomaMary H Ward
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
Carcinogenesis 28:1210-6. 2007..Our results suggest that nitrite and nitrate intake from processed meat intake increases the risk of colorectal adenoma after accounting for HCA and PAH... - Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohortNeal D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Rockville, MD 20852, USA
J Natl Cancer Inst 102:1354-65. 2010..Several plausible mechanisms, including fat, iron, heterocyclic amines, and N-nitroso compounds, link meat intake with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Few studies have investigated these associations... - A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this associationAmanda J Cross
Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 70:2406-14. 2010..In conclusion, we found a positive association for red and processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from meat may explain these associations... - Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis CNeal D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Hepatology 50:1360-9. 2009..Tea intake was not associated with outcomes. CONCLUSION: In a large prospective study of participants with advanced hepatitis C-related liver disease, regular coffee consumption was associated with lower rates of disease progression... - A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in IndiaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Nutr J 10:12. 2011..The role of diet in India's rapidly progressing chronic disease epidemic is unclear; moreover, diet may vary considerably across North-South regions... - Measurement of spices and seasonings in India: opportunities for cancer epidemiology and preventionLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Asian Pac J Cancer Prev 11:1621-9. 2010.... - A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risksNatasa Tasevska
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
Am J Clin Nutr 89:1884-94. 2009..Red and processed meat consumption may play a role in lung cancer pathogenesis because of these meats' fat and carcinogen content... - Dietary meat intake in relation to colorectal adenoma in asymptomatic womenLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Am J Gastroenterol 104:1231-40. 2009.... - Meat and components of meat and the risk of bladder cancer in the NIH-AARP Diet and Health StudyLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Cancer 116:4345-53. 2010..The authors comprehensively investigated the association between meat and meat components and bladder cancer... - Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 69:1877-84. 2009..The observed effect provides evidence to support the hypothesis that HCAs may act as promoters of malignant transformation by altering mitogenic signaling... - A prospective study of serum C-reactive protein and colorectal cancer risk in menMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 66:2483-7. 2006..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer... - Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention studyAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
Int J Cancer 118:3147-52. 2006..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk... - Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control studyMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Carcinogenesis 26:637-42. 2005..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis... - A prospective study of meat and meat mutagens and prostate cancer riskAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Res 65:11779-84. 2005..01-1.61). In conclusion, very well done meat was positively associated with prostate cancer risk. In addition, this study lends epidemiologic support to the animal studies, which have implicated PhIP as a prostate carcinogen... - Meat-related mutagens/carcinogens in the etiology of colorectal cancerAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Environ Mol Mutagen 44:44-55. 2004..Here, we review the current epidemiologic knowledge of meat-related mutagens, and evaluate the types of studies that may be required in the future to clarify the association between meat consumption and colorectal cancer... - Relative validity of a food frequency questionnaire with a meat-cooking and heterocyclic amine moduleMarie Cantwell
Nutrition Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Cancer Epidemiol Biomarkers Prev 13:293-8. 2004..In conclusion, although the FFQ and meat module underestimated absolute MeIQx and PhIP intake, its ability to rank individuals according to intake was acceptable... - Urinary mutagenesis and fried red meat intake: influence of cooking temperature, phenotype, and genotype of metabolizing enzymes in a controlled feeding studyUlrike Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7273, USA
Environ Mol Mutagen 43:53-74. 2004..The data from this study indicate that urinary mutagenicity correlates with mutagenic exposure from cooked meat and can potentially be used as a marker in etiological studies on cancer... - Urinary mutagenicity and colorectal adenoma riskUlrike Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 7273, USA
Cancer Epidemiol Biomarkers Prev 12:1253-6. 2003..2-13.9, comparing the highest with the lowest quintile). In our study population, diet may have contributed to mutagenic exposure, which was positively associated with colorectal adenoma risk... - Meat, fat, and their subtypes as risk factors for colorectal cancer in a prospective cohort of womenAndrew Flood
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 158:59-68. 2003..This study provided no evidence of an association between either meat or fat (or any of their subtypes) and colorectal cancer incidence, but the authors cannot rule out the possibility of a modest association... - Dietary fibre and colorectal adenoma in a colorectal cancer early detection programmeUlrike Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, DHHS, MD 20892 7273, USA
Lancet 361:1491-5. 2003..Although dietary fibre has been reported to have no association with colorectal adenoma and cancer, in some studies this topic remains controversial... - Highlights of the eighth international conference on carcinogenic/mutagenic N-substituted aryl compoundsElizabeth G Snyderwine
Chemical Carcinogenesis Section, Laboratory of Experimental Carcinogenesis, National Cancer Institute, Bethesda, MD 20892 4258, USA
Mutat Res 506:1-8. 2002.... - Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomasNaoko Ishibe
Genetic Epidemioly Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
Pharmacogenetics 12:145-50. 2002..Further study of larger populations is needed to confirm and extend these observations... - A correlation study of organochlorine levels in serum, breast adipose tissue, and gluteal adipose tissue among breast cancer cases in IndiaJennifer A Rusiecki
Occupational and Environmental Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Bethesda, MD 20892 7240, USA
Cancer Epidemiol Biomarkers Prev 14:1113-24. 2005..However, such measurements are a combination of both recent exposures and past exposures, which have metabolized slowly and may still persist. Therefore, investigators should use caution when assigning a level as lifetime body burden... - No effect of meat, meat cooking preferences, meat mutagens or heme iron on lung cancer risk in the prostate, lung, colorectal and ovarian cancer screening trialNatasa Tasevska
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Int J Cancer 128:402-11. 2011..In this population, we found no association between meat type, cooking method, doneness level or intake of specific meat mutagens or heme iron and lung cancer risk... - Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control studyAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
Carcinogenesis 27:293-7. 2006..39 (0.22-0.70); P trend = 0.004]. Overall, our study suggests that consumption of meat, whether or not it is well-done, does not increase the risk of NHL. Furthermore, neither HCAs nor B[a]P from meat increase the risk of NHL... - Vitamin D, calcium, and vitamin D receptor polymorphism in colorectal adenomasU Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 10:1267-74. 2001..The VDR FokI polymorphism was not significantly associated with colorectal adenoma and did not modify the effect of vitamin D or calcium. In conclusion, the study results suggested a protective effect for vitamin D on colorectal adenoma... - Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and USTanuja Rastogi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Int J Epidemiol 37:147-60. 2008..Examining such rates may provide us with insights into future aetiological research possibilities as well as screening and prevention... - Opportunities for cancer epidemiology in developing countriesTanuja Rastogi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, Maryland 20852, USA
Nat Rev Cancer 4:909-17. 2004..What are the challenges and advantages to performing large epidemiological studies in developing nations?.. - Highly sensitive chemiluminescence immunoassay for benzo[a]pyrene-DNA adducts: validation by comparison with other methods, and use in human biomonitoringRao L Divi
National Cancer Institute, NIH, Bethesda, MD 20892-4255, USA
Carcinogenesis 23:2043-9. 2002..95). Coded duplicate DNA samples from 15 individuals were assayed four times gave an inter-assay CV of 13.8%... - Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancerLesley M Butler
Department of Public Health Sciences, Division of Epidemiology, University of California, Davis, California, USA
Cancer Epidemiol Biomarkers Prev 14:1626-32. 2005..2-4.8), compared with less than the median daily intake and UGT1A7 high/intermediate genotypes. These data suggest that the associations among cooked meat-derived compound exposure, and colon cancer are modified by the UGT1A7 genotype... - Association of prostate cancer with rapid N-acetyltransferase 1 (NAT1*10) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control studyDavid W Hein
Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
Environ Mol Mutagen 40:161-7. 2002..This finding should be investigated further in larger cohorts and in other ethnic populations... - Meat intake and cooking techniques: associations with pancreatic cancerKristin E Anderson
University of Minnesota, Minneapolis, MN 55454, USA
Mutat Res 506:225-31. 2002..We conclude that grilled red meat intake is a risk factor for pancreatic cancer and that method of meat preparation in addition to total intake is important in assessing the effects of meat consumption in epidemiologic studies... - Well-done red meat, metabolic phenotypes and colorectal cancer in HawaiiLoic Le Marchand
Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street Suite 407, Honolulu, HI 96813, USA
Mutat Res 506:205-14. 2002..An attempt to examine the risk associated with specific HAAs suggested that the main HAAs increase risk of rectal cancer in men and that they do not appreciably affect risk of rectal cancer in women or of colon cancer in either sex... - Metabolites of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human urine after consumption of charbroiled or fried beefPaul T Strickland
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School Public Health, Baltimore, MD 21205
Mutat Res 506:163-73. 2002.... - Meat mutagens and risk of distal colon adenoma in a cohort of U.S. menKana Wu
Department of Nutrition, Harvard School of Public Health, Building 2, 665 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 15:1120-5. 2006..Because mutagens other than heterocyclic amines also contribute to MDM, our results suggest that mutagens other than heterocyclic amines in cooked meats may also play a role in increasing the risk of distal adenoma... - Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysisAbbas Parsian
Birth Defects Center, Department of Molecular and Cellular Biology, University of Louisville Health Sciences Center, Louisville, Kentucky, USA
Am J Med Genet B Neuropsychiatr Genet 117:46-50. 2003..After Bonferroni's correction for multiple tests none of the results remained significant at P < 0.05. Our results indicate that MAO-A may play a role in the development of alcoholism but the gene effect is very small... - Dietary carotenoids, vegetables, and lung cancer risk in women: the Missouri women's health study (United States)Margaret E Wright
Department of Epidemiology, and Public Health, Yale University School of Medicine, New Haven, CT 05620-8034, USA
Cancer Causes Control 14:85-96. 2003..CONCLUSIONS: These results indicate that consumption of a wide variety of vegetables has a greater bearing on lung cancer risk in a population of smoking and nonsmoking women than intake of any specific carotenoid or total carotenoids... - Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to riskSusan Nowell
Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA
Mutat Res 506:175-85. 2002.... - Quantitation of 13 heterocyclic aromatic amines in cooked beef, pork, and chicken by liquid chromatography-electrospray ionization/tandem mass spectrometryWeijuan Ni
Division of Environmental Disease Prevention and Division of Molecular Medicine, Wadsworth Center, New York State Department of Health, Albany, NY 12201 0509, USA
J Agric Food Chem 56:68-78. 2008..The toxicological properties of these recently discovered I gQx derivatives warrant further investigation and assessment... - Meat consumption and risk of colorectal cancerAnn Chao
Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329-4251, USA
JAMA 293:172-82. 2005.... - Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic studyLesley M Butler
University of California Davis, Department of Public Health Sciences, Division of Epidemiology, Davis, CA 95616, USA
Mutat Res 638:162-74. 2008.... - Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp riskAesun Shin
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 8th Floor, 2525 West End Avenue, Nashville, TN 37203, USA
Cancer Epidemiol Biomarkers Prev 17:320-9. 2008..These results provide strong evidence for a modifying effect of metabolizing genes on the association of meat intake and HCA exposure with colorectal polyp risk... - Meat intake, preparation methods, mutagens and colorectal adenoma recurrenceMaria Elena Martinez
Arizona Cancer Center, University of Arizona, Tucson, AZ, USA
Carcinogenesis 28:2019-27. 2007..07-2.82) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (OR = 1.68; 95% CI = 1.03-2.75). Our results support a meat mutagen exposure hypothesis as a potential mechanism for recurrence of clinically significant adenomatous polyps... - Food, nutrient and heterocyclic amine intake and the risk of bladder cancerReina Garcia Closas
Research Unit, University Hospital of Canary Islands, La Laguna, Tenerife, Spain
Eur J Cancer 43:1731-40. 2007..6 (0.4, 0.8) p trend=0.0006) and retinol (0.6 (0.4-0.9) p trend=0.004). Our findings indicate that fruit and vegetable intake, as well as B-vitamin and retinol intake might be associated with a reduced bladder cancer risk... - Dietary mutagen exposure and risk of pancreatic cancerDonghui Li
Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Cancer Epidemiol Biomarkers Prev 16:655-61. 2007..09 and 0.099, respectively. These data support the hypothesis that dietary mutagen exposure alone and in interaction with other factors contribute to the development of pancreatic cancer... - Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancerKristin E Anderson
School of Public Health, University of Minnesota, Minneapolis, 55454, USA
Cancer Epidemiol Biomarkers Prev 14:2261-5. 2005..We sought to assess the association between dietary intake of HCA and benzo(a)pyrene [B(a)P] and exocrine pancreatic cancer in a population-based case-control study... - UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-AmericansHugo Girard
Pharmacogenomics Laboratory, CHUQ Research Center and Faculty of Pharmacy, Laval University, G1V 4G2 Quebec, Canada
Mutat Res 644:56-63. 2008..7 ng/day and combined high/intermediate genotypes. These data support a hypothesis that UGTs modify the association between meat-derived PAH exposure and colon cancer by their role in the elimination of dietary carcinogens... - Association of a variation in the promoter region of the brain-derived neurotrophic factor gene with familial Parkinson's diseaseAbbas Parsian
Birth Defects Center, University of Louisville Health Sciences Center, Department of Molecular and Cellular Biology, 501 S Preston Street, Room 301, Louisville, KY 40202, USA
Parkinsonism Relat Disord 10:213-9. 2004..Our data indicate the possibility of linkage disequilibrium between the C270T variation and a mutation in coding region of the BDNF gene and suggest that this gene may play a role in the development of familial PD... - Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp StudyAesun Shin
Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2587, USA
Int J Cancer 121:136-42. 2007..This study provides additional support for a positive association of high intake of red meat with colorectal adenomas, and suggests that high intake of meats and meat carcinogens may also be associated with hyperplastic polyps...