Affiliation: National Institutes of Health
- Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodiesKailash C Pandey
Malaria Research Group, International Centre for Genetic Engineering and Biotechnology, P O Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India
Mol Biochem Parasitol 123:23-33. 2002..falciparum field isolate that invades erythrocytes using multiple pathways. These observations support the development of recombinant PfF2 as a vaccine candidate for P. falciparum malaria...
- Biochemical and immunological characterization of bacterially expressed and refolded Plasmodium falciparum 42-kilodalton C-terminal merozoite surface protein 1Sanjay Singh
Malaria Vaccine Development Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
Infect Immun 71:6766-74. 2003..falciparum. The protection correlated with antibody-dependent mechanisms. Thus, this new construct, E. coli MSP1(42), is a viable candidate for human vaccine trials...
- Montanide ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulationsAaron P Miles
Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 5640 Fishers Lane, Twinbrook I Room 1118, Rockville, MD 20852, USA
Vaccine 23:2530-9. 2005....
- Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activitySanjay Singh
Antigen Research Section, Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases National Institutes of Health, TW1, Rockville, Maryland 20852, USA
Infect Immun 74:4573-80. 2006....
- Recombinant Plasmodium falciparum reticulocyte homology protein 4 binds to erythrocytes and blocks invasionDeepak Gaur
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Twinbrook III, 12735 Twinbrook Parkway, Bethesda, MD 20892 8132, USA
Proc Natl Acad Sci U S A 104:17789-94. 2007..These findings suggest that, although PfRH4 is required for invasion of neuraminidase-treated erythrocytes by Dd2/NM, it is inaccessible for antibody-mediated inhibition of the invasion process...
- posttranslational modification of recombinant Plasmodium falciparum apical membrane antigen 1: impact on functional immune responses to a malaria vaccine candidateBirgitte Giersing
Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, Twinbrook I, Room 1210A, 5640 Fisher Lane, Rockville, Maryland 20852, USA
Infect Immun 73:3963-70. 2005..coli- and P. pastoris-derived antigens are immunologically and functionally equivalent and are unaffected by the posttranslational modification resulting from expression in these two systems...
- Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in miceKathrin Kastenmüller
Vaccine Research Center and Cellular Immunology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Infect Immun 81:789-800. 2013..Overall, these data suggest that full-length CS proteins and poly(I · C)LC or GLA-SE offer a simple vaccine formulation to be used alone or in combination with other vaccines for preventing malaria infection...
- The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structureMichael M Klein
Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
PLoS Pathog 4:e1000147. 2008..This new understanding of PfEMP1 structure will allow the use of better-defined PfEMP1 domains for functional studies, for the design of candidate vaccines, and for understanding the molecular basis of cytoadherence...
- Domain III of Plasmodium falciparum apical membrane antigen 1 binds to the erythrocyte membrane protein KxKentaro Kato
Laboratory of Malaria and Vector Research and Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8132, USA
Proc Natl Acad Sci U S A 102:5552-7. 2005....
- Antibody responses to Plasmodium falciparum vaccine candidate antigens in three areas distinct with respect to altitudeGodfree Mlambo
Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Acta Trop 100:70-8. 2006..falciparum in vitro. Our data revealed that highest growth inhibition correlated with the highest levels of MSP-1 antibody values...
- The real greenhouse effectSanjay Singh
Indian J Dermatol Venereol Leprol 73:52; author reply 52. 2007
- Floating osmotic drug delivery system of ranitidine hydrochloride: development and evaluation--a technical notePramod Kumar
Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi 221005, U P, India
AAPS PharmSciTech 9:480-5. 2008
- Studies on biodegradable polymeric nanoparticles of risperidone: in vitro and in vivo evaluationMadaswamy S Muthu
Institute of Medical Sciences, Department of Pharmacology, Banaras Hindu University, Varanasi 221005, India
Nanomedicine (Lond) 3:305-19. 2008..The aim of this work was to develop extended-release risperidone nanoparticles for parenteral delivery (intravenous) and to reduce the dose-dependent extrapyramidal side effects of risperidone...