Joshua H Singer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Sustained Ca2+ entry elicits transient postsynaptic currents at a retinal ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, National Institutes of Health National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 4066, USA
    J Neurosci 23:10923-33. 2003
  2. ncbi request reprint Coordinated multivesicular release at a mammalian ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, NIH NINDS, 36 Convent Drive, MSC 4066, Building 36 Room 2C 09, Bethesda, Maryland 20892, USA
    Nat Neurosci 7:826-33. 2004
  3. ncbi request reprint Vesicle depletion and synaptic depression at a mammalian ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Neurophysiol 95:3191-8. 2006
  4. ncbi request reprint Fast neurotransmitter release triggered by Ca influx through AMPA-type glutamate receptors
    Andres E Chavez
    Synaptic Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 3701, USA
    Nature 443:705-8. 2006
  5. pmc Multivesicular release and saturation of glutamatergic signalling at retinal ribbon synapses
    Joshua H Singer
    Departments of Ophthalmology and Physiology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Tarry 5 715, Chicago, IL 60611, USA
    J Physiol 580:23-9. 2007
  6. doi request reprint GABA is an endogenous ligand for synaptic glycine receptors
    Joshua H Singer
    Departments of Ophthalmology and Physiology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Tarry 5 715, Chicago, IL 60611, USA
    Neuron 57:475-7. 2008

Detail Information

Publications6

  1. ncbi request reprint Sustained Ca2+ entry elicits transient postsynaptic currents at a retinal ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, National Institutes of Health National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 4066, USA
    J Neurosci 23:10923-33. 2003
    ..We conclude that the time course of vesicle release from RBCs is inherently transient and, together with the fast kinetics of postsynaptic AMPARs, speeds transmission at this synapse...
  2. ncbi request reprint Coordinated multivesicular release at a mammalian ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, NIH NINDS, 36 Convent Drive, MSC 4066, Building 36 Room 2C 09, Bethesda, Maryland 20892, USA
    Nat Neurosci 7:826-33. 2004
    ..The release synchrony reflected in these multivesicular events suggests that release within an active zone is coordinated during MVR...
  3. ncbi request reprint Vesicle depletion and synaptic depression at a mammalian ribbon synapse
    Joshua H Singer
    Synaptic Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Neurophysiol 95:3191-8. 2006
    ..The small RRP and very high release probability likely contribute to the transient characteristics of neurotransmission at RBC synapses...
  4. ncbi request reprint Fast neurotransmitter release triggered by Ca influx through AMPA-type glutamate receptors
    Andres E Chavez
    Synaptic Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 3701, USA
    Nature 443:705-8. 2006
    ..These results describe a fast synapse that operates independently of VGCCs and membrane depolarization and reveal a previously unknown form of feedback inhibition within a neural circuit...
  5. pmc Multivesicular release and saturation of glutamatergic signalling at retinal ribbon synapses
    Joshua H Singer
    Departments of Ophthalmology and Physiology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Tarry 5 715, Chicago, IL 60611, USA
    J Physiol 580:23-9. 2007
    ..Here, I discuss three postsynaptic mechanisms that permit three different retinal synapses to utilize MVR...
  6. doi request reprint GABA is an endogenous ligand for synaptic glycine receptors
    Joshua H Singer
    Departments of Ophthalmology and Physiology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Tarry 5 715, Chicago, IL 60611, USA
    Neuron 57:475-7. 2008
    ..Lu, Rubio, and Trussell, however, demonstrate in this issue of Neuron the first instance of cotransmission in which two neurotransmitters act on the same postsynaptic receptor...