Research Topics
| Lone SimonsenSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Effect of rotavirus vaccination programme on trends in admission of infants to hospital for intussusceptionL Simonsen
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
Lancet 358:1224-9. 2001..Studies have reported a temporal association between a first dose of rotavirus vaccine (Rotashield) and infant intussusception. We investigated the effect of Rotashield vaccination use on intussusception admissions in ten US states...- Commentary: Observational studies and the art of accurately measuring influenza vaccine benefitsLone Simonsen
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 6700-B Rockledge Drive, Bethesda, MD 20892, USA
Int J Epidemiol 36:631-2. 2007 - More on RotaShield and intussusception: the role of age at the time of vaccinationL Simonsen
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Infect Dis 192:S36-43. 2005..We explore here the effect of age on the risk of intussusception... - Impact of influenza vaccination on seasonal mortality in the US elderly populationLone Simonsen
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 6613, USA
Arch Intern Med 165:265-72. 2005..We tried to reconcile these conflicting findings by adjusting excess mortality estimates for aging and increased circulation of influenza A(H3N2) viruses... - A hexavalent human rotavirus-bovine rotavirus (UK) reassortant vaccine designed for use in developing countries and delivered in a schedule with the potential to eliminate the risk of intussusceptionAlbert Z Kapikian
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Infect Dis 192:S22-9. 2005..e., ages 3-4 months through age 9 months). In this way, there may be the potential to eliminate or at least significantly decrease the risk of intussusception associated with rotavirus vaccination... 
Epidemiological characteristics and underlying risk factors for mortality during the autumn 2009 pandemic wave in MexicoGerardo Chowell
Division of Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 7:e41069. 2012..Elucidating the role of the underlying risk factors for severe outcomes of the 2009 A/H1N1 influenza pandemic could be crucial to define priority risk groups in resource-limited settings in future pandemics...- Prioritization of influenza pandemic vaccination to minimize years of life lostMark A Miller
Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 198:305-11. 2008.... - Mortality benefits of influenza vaccination in elderly people: an ongoing controversyLone Simonsen
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
Lancet Infect Dis 7:658-66. 2007..The remaining evidence base is currently insufficient to indicate the magnitude of the mortality benefit, if any, that elderly people derive from the vaccination programme... - The origin and global emergence of adamantane resistant A/H3N2 influenza virusesMartha I Nelson
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Virology 388:270-8. 2009.... - Synchrony, waves, and spatial hierarchies in the spread of influenzaCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Science 312:447-51. 2006..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints... 
Influenza in tropical regionsCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS Med 3:e89. 2006- Influenza-related mortality trends in Japanese and American seniors: evidence for the indirect mortality benefits of vaccinating schoolchildrenVivek Charu
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 6:e26282. 2011..Here we characterize the indirect mortality benefits of vaccinating schoolchildren based on data from Japan and the US... - Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemicCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Vaccine 24:6701-7. 2006..Surprisingly in Liverpool, considered the 'epicenter' of the severe 1951 epidemic, the mortality impact and transmissibility even surpassed the 1918 pandemic... - 1951 influenza epidemic, England and Wales, Canada, and the United StatesCecile Viboud
National Institutes of Health, Fogarty International Center, Bethesda, Maryland 20892, USA
Emerg Infect Dis 12:661-8. 2006..Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza... - Seasonality of influenza in Brazil: a traveling wave from the Amazon to the subtropicsWladimir J Alonso
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 6710, USA
Am J Epidemiol 165:1434-42. 2007..The direction of the traveling wave suggests that environmental forces (temperature, humidity) play a more important role than population factors (density, travel) in driving the timing of influenza epidemics across Brazil... - Impact of the 2009 influenza pandemic on pneumococcal pneumonia hospitalizations in the United StatesDaniel M Weinberger
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 205:458-65. 2012..Infection with influenza virus increases the risk for developing pneumococcal disease. The A/H1N1 influenza pandemic in autumn 2009 provided a unique opportunity to evaluate this relationship... - Mortality burden of the A/H1N1 pandemic in Mexico: a comparison of deaths and years of life lost to seasonal influenzaVivek Charu
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, 16 Center Drive, Bethesda, MD 20892, USA
Clin Infect Dis 53:985-93. 2011..Here, we compare excess mortality rates and years of life lost (YLL) for pandemic and seasonal influenza in Mexico and evaluate laboratory-confirmed death reports... - Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United StatesLone Simonsen
Sage Analytica, Bethesda, Maryland, USA
MBio 2:e00309-10. 2011.... - The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistanceLone Simonsen
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
Mol Biol Evol 24:1811-20. 2007..More generally, these findings illustrate that drug selection pressure is not the sole factor determining the evolution and maintenance of drug resistance in human pathogens... - Multinational impact of the 1968 Hong Kong influenza pandemic: evidence for a smoldering pandemicCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 192:233-48. 2005..We further explored the global pattern of mortality caused by the pandemic during this period... - Mortality and morbidity burden associated with A/H1N1pdm influenza virus: Who is likely to be infected, experience clinical symptoms, or die from the H1N1pdm 2009 pandemic virus ?Mark Miller
National Institutes of Health Fogarty International Center, National Institutes of Health, Bethesda, MD, USA Department of Global Health, George Washington University, School of Public Health and Health Services, DC International Society for Disease Surveillace and University of Cambridge and Fogarty International Center NIH
PLoS Curr 1:RRN1013. 2009..Here we use lessons from past influenza pandemics and recent information about the H1N1pdm pandemic to discuss variations in H1N1pdm disease burden with age, underlying risk factors, and geography... - Severe acute respiratory syndrome: developing a research responseJohn R La Montagne
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 31, Rm 7A03, Bethesda, MD 20892, USA
J Infect Dis 189:634-41. 2004.... - Natality decline and miscarriages associated with the 1918 influenza pandemic: the Scandinavian and United States experiencesKimberly Bloom-Feshbach
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 204:1157-64. 2011..We examined the relationship between influenza and birth rates during the 1918 pandemic in the United States, Denmark, Sweden, and Norway... - Antibody response to influenza vaccination in the elderly: a quantitative reviewKatherine Goodwin
National Institutes of Allergy and Infectious Diseases, Office of Global Affairs, 6610 Rockledge Drive, Room 2033, Bethesda, MD 20818, USA
Vaccine 24:1159-69. 2006..We conclude that the antibody response in the elderly is considerably lower than in younger adults. This highlights the need for more immunogenic vaccine formulations for the elderly... - Mortality burden of the 2009 A/H1N1 influenza pandemic in France: comparison to seasonal influenza and the A/H3N2 pandemicMagali Lemaitre
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS ONE 7:e45051. 2012..We estimate the age- and cause-specific excess mortality impact of the pandemic in France, relative to that of other countries and past epidemic and pandemic seasons... - Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United StatesMartha I Nelson
Fogarty International Center, National Institutes of Health, 16 Center Drive, Building 16, Room 202, Bethesda, MD 20892, USA
J Virol 85:828-34. 2011.... - Does seasonal influenza vaccination increase the risk of illness with the 2009 A/H1N1 pandemic virus?Cecile Viboud
Division of Epidemiology and Population Studies, Fogarty International Center, NIH, Bethesda, MD, USA
Int J Risk Saf Med 23:97-102. 2011..1371/journal.pmed.1000258. In three case-control studies and a household transmission cohort, Danuta Skowronski and colleagues find an association between prior seasonal flu vaccination and increased risk of 2009 pandemic H1N1 flu... - Reappraisal of the association of intussusception with the licensed live rotavirus vaccine challenges initial conclusionsBrian R Murphy
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
J Infect Dis 187:1301-8. 2003 - Epidemiological evidence of an early wave of the 1918 influenza pandemic in New York CityDonald R Olson
Department of Epidemiology and Center for Public Health Preparedness, Columbia University, New York, NY 10032, USA
Proc Natl Acad Sci U S A 102:11059-63. 2005..The timing, magnitude, and age distribution of this mortality shift provide strong evidence that an early wave of the pandemic virus was present in New York City during February-April 1918... - Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003Thea Kølsen Fischer
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA
J Infect Dis 195:1117-25. 2007..The HCUP database serves as a sensitive and robust data source for monitoring the impact of a rotavirus-immunization program in the United States... - Ecological studies, rotavirus vaccination, and intussusceptionLone Simonsen
Lancet 359:1066-7; author reply 1066. 2002 - Mortality due to influenza in the United States--an annualized regression approach using multiple-cause mortality dataJonathan Dushoff
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
Am J Epidemiol 163:181-7. 2006..The study also uses regional death data to investigate the effects of cold weather on annualized excess deaths... - Stochastic processes are key determinants of short-term evolution in influenza a virusMartha I Nelson
Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
PLoS Pathog 2:e125. 2006..Thus, predicting future patterns of influenza virus evolution for vaccine strain selection is inherently complex and requires intensive surveillance, whole-genome sequencing, and phenotypic analysis... - Commentary: benefits of influenza vaccine in US elderly--new studies raise questionsW Paul Glezen
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Int J Epidemiol 35:352-3. 2006 - Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918Martha I Nelson
Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America
PLoS Pathog 4:e1000012. 2008..Intra-subtype reassortment therefore appears to be a more important process in the evolution and epidemiology of H1N1 influenza A virus than previously realized... - Trends in intussusception hospitalizations among US infants, 1993-2004: implications for monitoring the safety of the new rotavirus vaccination programJacqueline E Tate
Division of Viral Diseases, Epidemiology Branch, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 121:e1125-32. 2008.... - Vaccinating to protect a vulnerable subpopulationJonathan Dushoff
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
PLoS Med 4:e174. 2007..Here we investigate the question of how to protect a population against a disease when one group is particularly effective at spreading disease and another group is more vulnerable to the effects of the disease... - Trends for influenza-related deaths during pandemic and epidemic seasons, Italy, 1969-2001Caterina Rizzo
Istituto Superiore di Sanita, CNESPS, Rome, Italy
Emerg Infect Dis 13:694-9. 2007..When comparing northern, central, and southern Italy, we found a high level of synchrony in the amplitude of peaks of influenza-related deaths... - Influenza-related mortality in the Italian elderly: no decline associated with increasing vaccination coverageCaterina Rizzo
Department of Pharmaco Biology, University of Bari, Italy
Vaccine 24:6468-75. 2006..As in the US, our study challenges current strategies to best protect the elderly against mortality, warranting the need for better controlled trials with alternative vaccination strategies... - Rotavirus vaccinesLone Simonsen
N Engl J Med 354:1747-51; author reply 1747-51. 2006 - Epidemiologic characterization of the 1918 influenza pandemic summer wave in Copenhagen: implications for pandemic control strategiesViggo Andreasen
Department of Sciences, Roskilde University, Roskilde, Denmark
J Infect Dis 197:270-8. 2008..The 1918-1919 A/H1N1 influenza pandemic killed approximately 50 million people worldwide. Historical records suggest that an early pandemic wave struck Europe during the summer of 1918... - Phylogenetic analysis reveals the global migration of seasonal influenza A virusesMartha I Nelson
Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, USA
PLoS Pathog 3:1220-8. 2007.... - Respiratory syncytial virus infection in elderly adultsLone Simonsen
N Engl J Med 353:422-3; author reply 422-3. 2005 - Influenza vaccination in elderly peopleLone Simonsen
Lancet 366:2086. 2005 - Effectiveness of influenza vaccinationLone Simonsen
N Engl J Med 357:2729-30; author reply 2730-1. 2007 - Influenza and the winter increase in mortality in the United States, 1959-1999Thomas A Reichert
Entropy Research Institute, 262 West Saddle River Road, Upper Saddle River, NJ 07458, USA
Am J Epidemiol 160:492-502. 2004..Weather and other factors may determine the timing and modulate the magnitude of the winter-season increase in mortality, but the primary determinant appears to be the influenza virus... - Estimating deaths due to influenza and respiratory syncytial virusLone Simonsen
JAMA 289:2499-500; author reply 2500-2. 2003 - Air travel and the spread of influenza: important caveatsCecile Viboud
PLoS Med 3:e503; author reply e502. 2006 - Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United StatesMartha I Nelson
Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America
PLoS Pathog 4:e1000133. 2008....