Lone Simonsen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effect of rotavirus vaccination programme on trends in admission of infants to hospital for intussusception
    L Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet 358:1224-9. 2001
  2. ncbi request reprint More on RotaShield and intussusception: the role of age at the time of vaccination
    L Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Infect Dis 192:S36-43. 2005
  3. ncbi request reprint Impact of influenza vaccination on seasonal mortality in the US elderly population
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 6613, USA
    Arch Intern Med 165:265-72. 2005
  4. ncbi request reprint Commentary: Observational studies and the art of accurately measuring influenza vaccine benefits
    Lone Simonsen
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 6700 B Rockledge Drive, Bethesda, MD 20892, USA
    Int J Epidemiol 36:631-2. 2007
  5. ncbi request reprint A hexavalent human rotavirus-bovine rotavirus (UK) reassortant vaccine designed for use in developing countries and delivered in a schedule with the potential to eliminate the risk of intussusception
    Albert Z Kapikian
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Infect Dis 192:S22-9. 2005
  6. pmc Latitudinal variations in seasonal activity of influenza and respiratory syncytial virus (RSV): a global comparative review
    Kimberly Bloom-Feshbach
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e54445. 2013
  7. pmc Epidemiological characteristics and underlying risk factors for mortality during the autumn 2009 pandemic wave in Mexico
    Gerardo Chowell
    Division of Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e41069. 2012
  8. ncbi request reprint Mortality benefits of influenza vaccination in elderly people: an ongoing controversy
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet Infect Dis 7:658-66. 2007
  9. pmc Prioritization of influenza pandemic vaccination to minimize years of life lost
    Mark A Miller
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 198:305-11. 2008
  10. pmc The origin and global emergence of adamantane resistant A/H3N2 influenza viruses
    Martha I Nelson
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Virology 388:270-8. 2009

Detail Information

Publications51

  1. ncbi request reprint Effect of rotavirus vaccination programme on trends in admission of infants to hospital for intussusception
    L Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet 358:1224-9. 2001
    ..Studies have reported a temporal association between a first dose of rotavirus vaccine (Rotashield) and infant intussusception. We investigated the effect of Rotashield vaccination use on intussusception admissions in ten US states...
  2. ncbi request reprint More on RotaShield and intussusception: the role of age at the time of vaccination
    L Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Infect Dis 192:S36-43. 2005
    ..We explore here the effect of age on the risk of intussusception...
  3. ncbi request reprint Impact of influenza vaccination on seasonal mortality in the US elderly population
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 6613, USA
    Arch Intern Med 165:265-72. 2005
    ..We tried to reconcile these conflicting findings by adjusting excess mortality estimates for aging and increased circulation of influenza A(H3N2) viruses...
  4. ncbi request reprint Commentary: Observational studies and the art of accurately measuring influenza vaccine benefits
    Lone Simonsen
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 6700 B Rockledge Drive, Bethesda, MD 20892, USA
    Int J Epidemiol 36:631-2. 2007
  5. ncbi request reprint A hexavalent human rotavirus-bovine rotavirus (UK) reassortant vaccine designed for use in developing countries and delivered in a schedule with the potential to eliminate the risk of intussusception
    Albert Z Kapikian
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Infect Dis 192:S22-9. 2005
    ..e., ages 3-4 months through age 9 months). In this way, there may be the potential to eliminate or at least significantly decrease the risk of intussusception associated with rotavirus vaccination...
  6. pmc Latitudinal variations in seasonal activity of influenza and respiratory syncytial virus (RSV): a global comparative review
    Kimberly Bloom-Feshbach
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e54445. 2013
    ..There is limited information on influenza and respiratory syncytial virus (RSV) seasonal patterns in tropical areas, although there is renewed interest in understanding the seasonal drivers of respiratory viruses...
  7. pmc Epidemiological characteristics and underlying risk factors for mortality during the autumn 2009 pandemic wave in Mexico
    Gerardo Chowell
    Division of Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e41069. 2012
    ..Elucidating the role of the underlying risk factors for severe outcomes of the 2009 A/H1N1 influenza pandemic could be crucial to define priority risk groups in resource-limited settings in future pandemics...
  8. ncbi request reprint Mortality benefits of influenza vaccination in elderly people: an ongoing controversy
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet Infect Dis 7:658-66. 2007
    ..The remaining evidence base is currently insufficient to indicate the magnitude of the mortality benefit, if any, that elderly people derive from the vaccination programme...
  9. pmc Prioritization of influenza pandemic vaccination to minimize years of life lost
    Mark A Miller
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 198:305-11. 2008
    ....
  10. pmc The origin and global emergence of adamantane resistant A/H3N2 influenza viruses
    Martha I Nelson
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Virology 388:270-8. 2009
    ....
  11. ncbi request reprint Synchrony, waves, and spatial hierarchies in the spread of influenza
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Science 312:447-51. 2006
    ..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints...
  12. pmc Influenza-related mortality trends in Japanese and American seniors: evidence for the indirect mortality benefits of vaccinating schoolchildren
    Vivek Charu
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e26282. 2011
    ..Here we characterize the indirect mortality benefits of vaccinating schoolchildren based on data from Japan and the US...
  13. ncbi request reprint Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemic
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Vaccine 24:6701-7. 2006
    ..Surprisingly in Liverpool, considered the 'epicenter' of the severe 1951 epidemic, the mortality impact and transmissibility even surpassed the 1918 pandemic...
  14. pmc Influenza in tropical regions
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Med 3:e89. 2006
  15. pmc Mortality burden of the 2009 A/H1N1 influenza pandemic in France: comparison to seasonal influenza and the A/H3N2 pandemic
    Magali Lemaitre
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 7:e45051. 2012
    ..We estimate the age- and cause-specific excess mortality impact of the pandemic in France, relative to that of other countries and past epidemic and pandemic seasons...
  16. pmc 1951 influenza epidemic, England and Wales, Canada, and the United States
    Cecile Viboud
    National Institutes of Health, Fogarty International Center, Bethesda, Maryland 20892, USA
    Emerg Infect Dis 12:661-8. 2006
    ..Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza...
  17. ncbi request reprint Seasonality of influenza in Brazil: a traveling wave from the Amazon to the subtropics
    Wladimir J Alonso
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 6710, USA
    Am J Epidemiol 165:1434-42. 2007
    ..The direction of the traveling wave suggests that environmental forces (temperature, humidity) play a more important role than population factors (density, travel) in driving the timing of influenza epidemics across Brazil...
  18. ncbi request reprint Antibody response to influenza vaccination in the elderly: a quantitative review
    Katherine Goodwin
    National Institutes of Allergy and Infectious Diseases, Office of Global Affairs, 6610 Rockledge Drive, Room 2033, Bethesda, MD 20818, USA
    Vaccine 24:1159-69. 2006
    ..We conclude that the antibody response in the elderly is considerably lower than in younger adults. This highlights the need for more immunogenic vaccine formulations for the elderly...
  19. pmc Impact of the 2009 influenza pandemic on pneumococcal pneumonia hospitalizations in the United States
    Daniel M Weinberger
    Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 205:458-65. 2012
    ..Infection with influenza virus increases the risk for developing pneumococcal disease. The A/H1N1 influenza pandemic in autumn 2009 provided a unique opportunity to evaluate this relationship...
  20. pmc Mortality burden of the A/H1N1 pandemic in Mexico: a comparison of deaths and years of life lost to seasonal influenza
    Vivek Charu
    Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, 16 Center Drive, Bethesda, MD 20892, USA
    Clin Infect Dis 53:985-93. 2011
    ..Here, we compare excess mortality rates and years of life lost (YLL) for pandemic and seasonal influenza in Mexico and evaluate laboratory-confirmed death reports...
  21. ncbi request reprint Multinational impact of the 1968 Hong Kong influenza pandemic: evidence for a smoldering pandemic
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 192:233-48. 2005
    ..We further explored the global pattern of mortality caused by the pandemic during this period...
  22. ncbi request reprint The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Mol Biol Evol 24:1811-20. 2007
    ..More generally, these findings illustrate that drug selection pressure is not the sole factor determining the evolution and maintenance of drug resistance in human pathogens...
  23. pmc Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States
    Lone Simonsen
    Sage Analytica, Bethesda, Maryland, USA
    MBio 2:e00309-10. 2011
    ....
  24. pmc Mortality burden of the 2009-10 influenza pandemic in the United States: improving the timeliness of influenza severity estimates using inpatient mortality records
    Vivek Charu
    Fogarty International Center, National Institutes of Health, Bethesda, MD, USA Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Influenza Other Respi Viruses 7:863-71. 2013
    ..Delays in the release of national vital statistics hinder timely assessment of influenza severity, especially during pandemics. Inpatient mortality records could provide timelier estimates of influenza-associated mortality...
  25. pmc Mortality and morbidity burden associated with A/H1N1pdm influenza virus: Who is likely to be infected, experience clinical symptoms, or die from the H1N1pdm 2009 pandemic virus ?
    Mark Miller
    National Institutes of Health Fogarty International Center, National Institutes of Health, Bethesda, MD, USA Department of Global Health, George Washington University, School of Public Health and Health Services, DC International Society for Disease Surveillace and University of Cambridge and Fogarty International Center NIH
    PLoS Curr 1:RRN1013. 2009
    ..Here we use lessons from past influenza pandemics and recent information about the H1N1pdm pandemic to discuss variations in H1N1pdm disease burden with age, underlying risk factors, and geography...
  26. ncbi request reprint Severe acute respiratory syndrome: developing a research response
    John R La Montagne
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 31, Rm 7A03, Bethesda, MD 20892, USA
    J Infect Dis 189:634-41. 2004
    ....
  27. pmc Natality decline and miscarriages associated with the 1918 influenza pandemic: the Scandinavian and United States experiences
    Kimberly Bloom-Feshbach
    Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 204:1157-64. 2011
    ..We examined the relationship between influenza and birth rates during the 1918 pandemic in the United States, Denmark, Sweden, and Norway...
  28. pmc Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United States
    Martha I Nelson
    Fogarty International Center, National Institutes of Health, 16 Center Drive, Building 16, Room 202, Bethesda, MD 20892, USA
    J Virol 85:828-34. 2011
    ....
  29. ncbi request reprint Does seasonal influenza vaccination increase the risk of illness with the 2009 A/H1N1 pandemic virus?
    Cecile Viboud
    Division of Epidemiology and Population Studies, Fogarty International Center, NIH, Bethesda, MD, USA
    Int J Risk Saf Med 23:97-102. 2011
    ..1371/journal.pmed.1000258. In three case-control studies and a household transmission cohort, Danuta Skowronski and colleagues find an association between prior seasonal flu vaccination and increased risk of 2009 pandemic H1N1 flu...
  30. ncbi request reprint Reappraisal of the association of intussusception with the licensed live rotavirus vaccine challenges initial conclusions
    Brian R Murphy
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 187:1301-8. 2003
  31. ncbi request reprint Ecological studies, rotavirus vaccination, and intussusception
    Lone Simonsen
    Lancet 359:1066-7; author reply 1066. 2002
  32. ncbi request reprint Commentary: benefits of influenza vaccine in US elderly--new studies raise questions
    W Paul Glezen
    Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Int J Epidemiol 35:352-3. 2006
  33. ncbi request reprint Mortality due to influenza in the United States--an annualized regression approach using multiple-cause mortality data
    Jonathan Dushoff
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Am J Epidemiol 163:181-7. 2006
    ..The study also uses regional death data to investigate the effects of cold weather on annualized excess deaths...
  34. pmc Epidemiological evidence of an early wave of the 1918 influenza pandemic in New York City
    Donald R Olson
    Department of Epidemiology and Center for Public Health Preparedness, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 102:11059-63. 2005
    ..The timing, magnitude, and age distribution of this mortality shift provide strong evidence that an early wave of the pandemic virus was present in New York City during February-April 1918...
  35. ncbi request reprint Influenza-related mortality in the Italian elderly: no decline associated with increasing vaccination coverage
    Caterina Rizzo
    Department of Pharmaco Biology, University of Bari, Italy
    Vaccine 24:6468-75. 2006
    ..As in the US, our study challenges current strategies to best protect the elderly against mortality, warranting the need for better controlled trials with alternative vaccination strategies...
  36. pmc Stochastic processes are key determinants of short-term evolution in influenza a virus
    Martha I Nelson
    Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS Pathog 2:e125. 2006
    ..Thus, predicting future patterns of influenza virus evolution for vaccine strain selection is inherently complex and requires intensive surveillance, whole-genome sequencing, and phenotypic analysis...
  37. ncbi request reprint Rotavirus vaccines
    Lone Simonsen
    N Engl J Med 354:1747-51; author reply 1747-51. 2006
  38. pmc Vaccinating to protect a vulnerable subpopulation
    Jonathan Dushoff
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS Med 4:e174. 2007
    ..Here we investigate the question of how to protect a population against a disease when one group is particularly effective at spreading disease and another group is more vulnerable to the effects of the disease...
  39. pmc Trends for influenza-related deaths during pandemic and epidemic seasons, Italy, 1969-2001
    Caterina Rizzo
    Istituto Superiore di Sanita, CNESPS, Rome, Italy
    Emerg Infect Dis 13:694-9. 2007
    ..When comparing northern, central, and southern Italy, we found a high level of synchrony in the amplitude of peaks of influenza-related deaths...
  40. pmc Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918
    Martha I Nelson
    Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS Pathog 4:e1000012. 2008
    ..Intra-subtype reassortment therefore appears to be a more important process in the evolution and epidemiology of H1N1 influenza A virus than previously realized...
  41. pmc Trends in intussusception hospitalizations among US infants, 1993-2004: implications for monitoring the safety of the new rotavirus vaccination program
    Jacqueline E Tate
    Division of Viral Diseases, Epidemiology Branch, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 121:e1125-32. 2008
    ....
  42. pmc Epidemiologic characterization of the 1918 influenza pandemic summer wave in Copenhagen: implications for pandemic control strategies
    Viggo Andreasen
    Department of Sciences, Roskilde University, Roskilde, Denmark
    J Infect Dis 197:270-8. 2008
    ..The 1918-1919 A/H1N1 influenza pandemic killed approximately 50 million people worldwide. Historical records suggest that an early pandemic wave struck Europe during the summer of 1918...
  43. ncbi request reprint Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003
    Thea Kølsen Fischer
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA
    J Infect Dis 195:1117-25. 2007
    ..The HCUP database serves as a sensitive and robust data source for monitoring the impact of a rotavirus-immunization program in the United States...
  44. ncbi request reprint Influenza and the winter increase in mortality in the United States, 1959-1999
    Thomas A Reichert
    Entropy Research Institute, 262 West Saddle River Road, Upper Saddle River, NJ 07458, USA
    Am J Epidemiol 160:492-502. 2004
    ..Weather and other factors may determine the timing and modulate the magnitude of the winter-season increase in mortality, but the primary determinant appears to be the influenza virus...
  45. ncbi request reprint Influenza vaccination in elderly people
    Lone Simonsen
    Lancet 366:2086. 2005
  46. pmc Phylogenetic analysis reveals the global migration of seasonal influenza A viruses
    Martha I Nelson
    Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, USA
    PLoS Pathog 3:1220-8. 2007
    ....
  47. ncbi request reprint Effectiveness of influenza vaccination
    Lone Simonsen
    N Engl J Med 357:2729-30; author reply 2730-1. 2007
  48. ncbi request reprint Respiratory syncytial virus infection in elderly adults
    Lone Simonsen
    N Engl J Med 353:422-3; author reply 422-3. 2005
  49. pmc Air travel and the spread of influenza: important caveats
    Cecile Viboud
    PLoS Med 3:e503; author reply e502. 2006
  50. ncbi request reprint Estimating deaths due to influenza and respiratory syncytial virus
    Lone Simonsen
    JAMA 289:2499-500; author reply 2500-2. 2003
  51. pmc Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States
    Martha I Nelson
    Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS Pathog 4:e1000133. 2008
    ....