Research Topics
| George K SiberrySummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Fracture risk by HIV infection status in perinatally HIV-exposed childrenGeorge K Siberry
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 7510, USA
AIDS Res Hum Retroviruses 28:247-50. 2012..2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children...
Evaluation of viral load thresholds for predicting new World Health Organization stage 3 and 4 events in HIV-infected children receiving highly active antiretroviral therapyGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
J Acquir Immune Defic Syndr 60:214-8. 2012..This study evaluated a wide range of viral load (VL) thresholds to identify a cut-point that best predicts new clinical events in children on stable highly active antiretroviral therapy (HAART)...
Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infantsGeorge K Siberry
Pediatric Adolescent Maternal AIDS Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
AIDS 26:1151-9. 2012..To evaluate the association of tenofovir disoproxil fumarate (TDF) use during pregnancy with early growth parameters in HIV-exposed, uninfected (HEU) infants...
Safety and immunogenicity of quadrivalent meningococcal conjugate vaccine in 2- to 10-year-old human immunodeficiency virus-infected childrenGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Pediatr Infect Dis J 31:47-52. 2012....
Phase I/II, open-label trial of safety and immunogenicity of meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine in human immunodeficiency virus-infected adolescentsGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
Pediatr Infect Dis J 29:391-6. 2010..Quadrivalent meningococcal polysaccharide conjugate vaccine (MCV4) is routinely recommended for healthy youth in the United States, but there are no data about its use in HIV-infected people...
CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruptionGeorge K Siberry
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
J Acquir Immune Defic Syndr 57:223-9. 2011..To assess the characteristics and outcomes of antiretroviral treatment (ART) interruption (TI) in perinatally HIV-infected children...
Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care siteAllison L Agwu
Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
J Adolesc Health 50:471-7. 2012..We assessed the impact of receiving care at an adult or pediatric HIV clinical site on initiation and discontinuation of the first HAART regimen in behaviorally infected youth (BIY)...
Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescentsGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
Clin Immunol 142:201-8. 2012..29%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide...
Thinking about HIV infectionEvelyn P Simpkins
Division of General Pediatrics and Adolescent Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Pediatr Rev 30:337-48; quiz 349. 2009..Recommendations for immunizations and chemoprophylaxis vary with the patient's CD4 count. Condoms made from latex, polyurethane, or other synthetic materials have been shown to decrease the transmission of STIs, including HIV infection...
Associations of medically documented psychiatric diagnoses and risky health behaviors in highly active antiretroviral therapy-experienced perinatally HIV-infected youthSuad Kapetanovic
National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1276, USA
AIDS Patient Care STDS 25:493-501. 2011..33, p=0.015). There is a need for a continued close partnership between HIV specialty care providers and mental health services treating perinatally HIV-infected youth with an added focus on improving treatment adherence...
Growing up with HIV: children, adolescents, and young adults with perinatally acquired HIV infectionRohan Hazra
Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Center for Research for Mothers and Children, National Institutes of Health, Rockville, Maryland 20852, USA
Annu Rev Med 61:169-85. 2010....
Disparities in antiretroviral treatment: a comparison of behaviorally HIV-infected youth and adults in the HIV Research NetworkAllison L Agwu
Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
J Acquir Immune Defic Syndr 58:100-7. 2011..We hypothesized that behaviorally HIV-infected youth (BIY) ages 18 to 24 years are less likely than adults (25 years or older) to receive HAART and, once initiated, more likely to discontinue their first HAART regimen...
Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and AdolescentsGeorge K Siberry
Pediatric, Adolescent and Maternal AIDS PAMA Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
AIDS Res Treat 2012:627974. 2012..MRSA occurred at a rate of 11.1 infections/1,000 PY in HIV-infected youth but invasive disease was uncommon. Geographic location, black race, and increased VL, but not immunosuppression, were independently associated with MRSA risk...
Preexposure prophylaxis for adolescents and young adults at risk for HIV infection: is an ounce of prevention worth a pound of cure?Jill E Pace
Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 7510, USA
Clin Infect Dis 56:1149-55. 2013..YMSM and minority youth are at substantial HIV risk and urgently need effective HIV prevention tools for which the short and long-term benefits and risks have been carefully considered...
Antibody response to hepatitis A immunization among human immunodeficiency virus-infected children and adolescentsGeorge K Siberry
Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Pediatr Infect Dis J 27:465-8. 2008..In multivariate analysis, CD4 >or=25% and young age were independent predictors of HAV seropositivity. Of 7 children given a third HAV vaccine dose because of negative HAV antibody after 2 doses, 2 (29%) became seropositive...
Immune reconstitution syndrome precipitated by bacille Calmette Guerin after initiation of antiretroviral therapyGeorge K Siberry
Division of Pediatric Infectious Diseases and General Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Pediatr Infect Dis J 25:648-9. 2006..We report the earliest onset of BCG-related immune reconstitution syndrome developing 1 week after initiation of ART...
