George K Siberry

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Phase I/II, open-label trial of safety and immunogenicity of meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine in human immunodeficiency virus-infected adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
    Pediatr Infect Dis J 29:391-6. 2010
  2. pmc Fracture risk by HIV infection status in perinatally HIV-exposed children
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 7510, USA
    AIDS Res Hum Retroviruses 28:247-50. 2012
  3. pmc Evaluation of viral load thresholds for predicting new World Health Organization stage 3 and 4 events in HIV-infected children receiving highly active antiretroviral therapy
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
    J Acquir Immune Defic Syndr 60:214-8. 2012
  4. pmc Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants
    George K Siberry
    Pediatric Adolescent Maternal AIDS Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    AIDS 26:1151-9. 2012
  5. pmc Safety and immunogenicity of quadrivalent meningococcal conjugate vaccine in 2- to 10-year-old human immunodeficiency virus-infected children
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
    Pediatr Infect Dis J 31:47-52. 2012
  6. pmc CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruption
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 57:223-9. 2011
  7. pmc Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care site
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Adolesc Health 50:471-7. 2012
  8. doi request reprint Aggregate risk of cardiovascular disease among adolescents perinatally infected with the human immunodeficiency virus
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, MA K P, G R S Center for Biostatistics in AIDS Research, Boston, MA K P, J W, D L J, G R S, P L W Department of Pediatrics, Wayne State University School of Medicine, Children s Hospital of Michigan, Detroit S E L Division of Pediatric Clinical Research and Division of Pediatric Infectious Disease and Immunology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL D C L, G B S, J D W, T L M Saban Research Institute of Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA M E G Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis L A D M Department of Pediatrics, Tulane University Health Sciences Center, New Orleans, LA R B V D Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD G K S Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston W T S Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL L Y Division of Cardiology, University of Maryland School of Medicine, Brazil
    Circulation 129:1204-12. 2014
  9. pmc Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Clin Immunol 142:201-8. 2012
  10. pmc Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy
    Carla E Ransom
    Department of Obstetrics and Gynecology, Vanderbilt University, Nashville, TN Center for Biostatistics in AIDS Research and Department of Epidemiology, Harvard School of Public Health, Boston, MA Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD and Department of Obstetrics and Gynecology, Duke University Medical School, Durham, NC
    J Acquir Immune Defic Syndr 64:374-81. 2013

Detail Information

Publications21

  1. pmc Phase I/II, open-label trial of safety and immunogenicity of meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine in human immunodeficiency virus-infected adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
    Pediatr Infect Dis J 29:391-6. 2010
    ..Quadrivalent meningococcal polysaccharide conjugate vaccine (MCV4) is routinely recommended for healthy youth in the United States, but there are no data about its use in HIV-infected people...
  2. pmc Fracture risk by HIV infection status in perinatally HIV-exposed children
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 7510, USA
    AIDS Res Hum Retroviruses 28:247-50. 2012
    ..2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children...
  3. pmc Evaluation of viral load thresholds for predicting new World Health Organization stage 3 and 4 events in HIV-infected children receiving highly active antiretroviral therapy
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
    J Acquir Immune Defic Syndr 60:214-8. 2012
    ..This study evaluated a wide range of viral load (VL) thresholds to identify a cut-point that best predicts new clinical events in children on stable highly active antiretroviral therapy (HAART)...
  4. pmc Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants
    George K Siberry
    Pediatric Adolescent Maternal AIDS Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    AIDS 26:1151-9. 2012
    ..To evaluate the association of tenofovir disoproxil fumarate (TDF) use during pregnancy with early growth parameters in HIV-exposed, uninfected (HEU) infants...
  5. pmc Safety and immunogenicity of quadrivalent meningococcal conjugate vaccine in 2- to 10-year-old human immunodeficiency virus-infected children
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
    Pediatr Infect Dis J 31:47-52. 2012
    ....
  6. pmc CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruption
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 57:223-9. 2011
    ..To assess the characteristics and outcomes of antiretroviral treatment (ART) interruption (TI) in perinatally HIV-infected children...
  7. pmc Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care site
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Adolesc Health 50:471-7. 2012
    ..We assessed the impact of receiving care at an adult or pediatric HIV clinical site on initiation and discontinuation of the first HAART regimen in behaviorally infected youth (BIY)...
  8. doi request reprint Aggregate risk of cardiovascular disease among adolescents perinatally infected with the human immunodeficiency virus
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, MA K P, G R S Center for Biostatistics in AIDS Research, Boston, MA K P, J W, D L J, G R S, P L W Department of Pediatrics, Wayne State University School of Medicine, Children s Hospital of Michigan, Detroit S E L Division of Pediatric Clinical Research and Division of Pediatric Infectious Disease and Immunology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL D C L, G B S, J D W, T L M Saban Research Institute of Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA M E G Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis L A D M Department of Pediatrics, Tulane University Health Sciences Center, New Orleans, LA R B V D Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD G K S Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston W T S Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL L Y Division of Cardiology, University of Maryland School of Medicine, Brazil
    Circulation 129:1204-12. 2014
    ....
  9. pmc Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Clin Immunol 142:201-8. 2012
    ..29%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide...
  10. pmc Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy
    Carla E Ransom
    Department of Obstetrics and Gynecology, Vanderbilt University, Nashville, TN Center for Biostatistics in AIDS Research and Department of Epidemiology, Harvard School of Public Health, Boston, MA Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD and Department of Obstetrics and Gynecology, Duke University Medical School, Durham, NC
    J Acquir Immune Defic Syndr 64:374-81. 2013
    ..To determine whether maternal use of tenofovir disoproxil fumarate for treatment of HIV in pregnancy predicts fetal and infant growth...
  11. pmc Incidence of opportunistic illness before and after initiation of highly active antiretroviral therapy in children
    Steven R Nesheim
    From the Emory University School of Medicine Epidemiology Branch, Quantitative Sciences and Informatics Branch, Division of HIV AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention Northrop Grumman Inc, Atlanta, GA Pediatric Adolescent Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD Baylor College of Medicine, Houston, TX and University of South Florida School of Medicine, Tampa, FL
    Pediatr Infect Dis J 32:1089-95. 2013
    ..Little is known about immune reconstitution inflammatory syndrome in children in the United States...
  12. doi request reprint Thinking about HIV infection
    Evelyn P Simpkins
    Division of General Pediatrics and Adolescent Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Pediatr Rev 30:337-48; quiz 349. 2009
    ..Recommendations for immunizations and chemoprophylaxis vary with the patient's CD4 count. Condoms made from latex, polyurethane, or other synthetic materials have been shown to decrease the transmission of STIs, including HIV infection...
  13. doi request reprint Growing up with HIV: children, adolescents, and young adults with perinatally acquired HIV infection
    Rohan Hazra
    Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Center for Research for Mothers and Children, National Institutes of Health, Rockville, Maryland 20852, USA
    Annu Rev Med 61:169-85. 2010
    ....
  14. pmc Disparities in antiretroviral treatment: a comparison of behaviorally HIV-infected youth and adults in the HIV Research Network
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 58:100-7. 2011
    ..We hypothesized that behaviorally HIV-infected youth (BIY) ages 18 to 24 years are less likely than adults (25 years or older) to receive HAART and, once initiated, more likely to discontinue their first HAART regimen...
  15. pmc Associations of medically documented psychiatric diagnoses and risky health behaviors in highly active antiretroviral therapy-experienced perinatally HIV-infected youth
    Suad Kapetanovic
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1276, USA
    AIDS Patient Care STDS 25:493-501. 2011
    ..33, p=0.015). There is a need for a continued close partnership between HIV specialty care providers and mental health services treating perinatally HIV-infected youth with an added focus on improving treatment adherence...
  16. pmc Prevalence and predictors of elevated aspartate aminotransferase-to-platelet ratio index in Latin American perinatally HIV-infected children
    George K Siberry
    From the Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda Westat, Rockville, MD Department of Infectious Diseases, Hospital Federal dos Servidores do Estado Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro Vertical Transmission Unit, Femina Hospital, Porto Alegre Department of Pediatrics, University of São Paulo Faculty of Medicine of Ribeirão Preto, Ribeirão Preto and Department of Pediatrics, Federal University of Minas Gerais, Belo Horizonte, Brazil
    Pediatr Infect Dis J 33:177-82. 2014
    ..We characterized elevated aspartate aminotransferase-to-platelet ratio index (APRI), a marker of possible liver fibrosis, in perinatally HIV-infected children...
  17. pmc Evaluation of risk for late language emergence after in utero antiretroviral drug exposure in HIV-exposed uninfected infants
    Mabel L Rice
    From the Speech, Language, Hearing Department, University of Kansas, Lawrence, KS Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD Bronx Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, NY Northwestern University Feinberg School of Medicine, Psychiatry and Behavioral Sciences, Chicago, IL Epidemiology and Statistics Program, Division of Scientific Programs, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD Department of Research Pediatrics, Maternal, Child and Adolescent Program for Infectious Diseases and Virology, Keck School of Medicine of USC, Los Angeles, CA Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA and National Institute of Mental Health, National Institutes of Health, Bethesda, MD
    Pediatr Infect Dis J 32:e406-13. 2013
    ..Safety is a concern for infants who were HIV-exposed but uninfected, particularly for neurodevelopmental problems, such as language delays...
  18. pmc Preexposure prophylaxis for adolescents and young adults at risk for HIV infection: is an ounce of prevention worth a pound of cure?
    Jill E Pace
    Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 7510, USA
    Clin Infect Dis 56:1149-55. 2013
    ..YMSM and minority youth are at substantial HIV risk and urgently need effective HIV prevention tools for which the short and long-term benefits and risks have been carefully considered...
  19. pmc Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents
    George K Siberry
    Pediatric, Adolescent and Maternal AIDS PAMA Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
    AIDS Res Treat 2012:627974. 2012
    ..MRSA occurred at a rate of 11.1 infections/1,000 PY in HIV-infected youth but invasive disease was uncommon. Geographic location, black race, and increased VL, but not immunosuppression, were independently associated with MRSA risk...
  20. doi request reprint Antibody response to hepatitis A immunization among human immunodeficiency virus-infected children and adolescents
    George K Siberry
    Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 27:465-8. 2008
    ..In multivariate analysis, CD4 >or=25% and young age were independent predictors of HAV seropositivity. Of 7 children given a third HAV vaccine dose because of negative HAV antibody after 2 doses, 2 (29%) became seropositive...
  21. ncbi request reprint Immune reconstitution syndrome precipitated by bacille Calmette Guerin after initiation of antiretroviral therapy
    George K Siberry
    Division of Pediatric Infectious Diseases and General Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 25:648-9. 2006
    ..We report the earliest onset of BCG-related immune reconstitution syndrome developing 1 week after initiation of ART...