Meredith S Shiels

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc The epidemic of non-Hodgkin lymphoma in the United States: disentangling the effect of HIV, 1992-2009
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:1069-78. 2013
  2. pmc Free light chains and the risk of AIDS-defining opportunistic infections in HIV-infected individuals
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Clin Infect Dis 55:e103-8. 2012
  3. pmc Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Cancer 118:5630-6. 2012
  4. pmc Impact of the HIV epidemic on the incidence rates of anal cancer in the United States
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    J Natl Cancer Inst 104:1591-8. 2012
  5. pmc Increased risk of histologically defined cancer subtypes in human immunodeficiency virus-infected individuals: clues for possible immunosuppression-related or infectious etiology
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    Cancer 118:4869-76. 2012
  6. doi request reprint Proportions of Kaposi sarcoma, selected non-Hodgkin lymphomas, and cervical cancer in the United States occurring in persons with AIDS, 1980-2007
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 7059, Rockville, MD 20892, USA
    JAMA 305:1450-9. 2011
  7. pmc Cancer burden in the HIV-infected population in the United States
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    J Natl Cancer Inst 103:753-62. 2011
  8. pmc Increased risk of lung cancer in men with tuberculosis in the alpha-tocopherol, beta-carotene cancer prevention study
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 7059, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:672-8. 2011
  9. pmc Age at cancer diagnosis among persons with AIDS in the United States
    Meredith S Shiels
    National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
    Ann Intern Med 153:452-60. 2010
  10. pmc Lung cancer incidence and mortality among HIV-infected and HIV-uninfected injection drug users
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 55:510-5. 2010

Detail Information

Publications27

  1. pmc The epidemic of non-Hodgkin lymphoma in the United States: disentangling the effect of HIV, 1992-2009
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:1069-78. 2013
    ..NHL risk is strongly increased among HIV-infected people. Our understanding of trends in NHL incidence has been hampered by difficulties in separating HIV-infected NHL cases from general population rates...
  2. pmc Free light chains and the risk of AIDS-defining opportunistic infections in HIV-infected individuals
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Clin Infect Dis 55:e103-8. 2012
    ..We evaluated the association between circulating κ and λ free light chains (FLCs), which are markers of B-cell dysfunction, and risk of developing an AIDS-defining opportunistic infection in HIV-infected men...
  3. pmc Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Cancer 118:5630-6. 2012
    ....
  4. pmc Impact of the HIV epidemic on the incidence rates of anal cancer in the United States
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    J Natl Cancer Inst 104:1591-8. 2012
    ..Thus, the HIV epidemic may have influenced the increasing anal cancer trends in the United States. We estimated the impact of the HIV epidemic on trends in anal cancer incidence in the United States during 1980-2005...
  5. pmc Increased risk of histologically defined cancer subtypes in human immunodeficiency virus-infected individuals: clues for possible immunosuppression-related or infectious etiology
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    Cancer 118:4869-76. 2012
    ..Because histologically defined cancer subtypes have not been systematically evaluated, their risk was assessed among people with acquired immunodeficiency syndrome (AIDS)...
  6. doi request reprint Proportions of Kaposi sarcoma, selected non-Hodgkin lymphomas, and cervical cancer in the United States occurring in persons with AIDS, 1980-2007
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 7059, Rockville, MD 20892, USA
    JAMA 305:1450-9. 2011
    ....
  7. pmc Cancer burden in the HIV-infected population in the United States
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    J Natl Cancer Inst 103:753-62. 2011
    ..We estimated the annual number of cancers in the HIV-infected population, both with and without AIDS, in the United States...
  8. pmc Increased risk of lung cancer in men with tuberculosis in the alpha-tocopherol, beta-carotene cancer prevention study
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 7059, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:672-8. 2011
    ..Tuberculosis may increase lung cancer risk through substantial and prolonged pulmonary inflammation. However, prospective data on tuberculosis and lung cancer risk are limited...
  9. pmc Age at cancer diagnosis among persons with AIDS in the United States
    Meredith S Shiels
    National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
    Ann Intern Med 153:452-60. 2010
    ..Studies have reported young ages at cancer diagnosis in HIV-infected persons and have suggested that HIV accelerates carcinogenesis. However, these comparisons did not account for differences in population age structures...
  10. pmc Lung cancer incidence and mortality among HIV-infected and HIV-uninfected injection drug users
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 55:510-5. 2010
    ..To examine the impact of HIV on lung cancer incidence and survival...
  11. pmc Circulating markers of interstitial lung disease and subsequent risk of lung cancer
    Meredith S Shiels
    Infections and Immunoepidemiology Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:2262-72. 2011
    ..Circulating levels of surfactant protein-D (SP-D) and Krebs von Lungren-6 (KL-6) are elevated in interstitial lung disease patients and may be useful markers of processes contributing to lung cancer...
  12. pmc A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 52:611-22. 2009
    ..To estimate summary standardized incidence ratios (SIRs) of non-AIDS cancers among HIV-infected individuals compared with general population rates overall and stratified by gender, AIDS, and highly active antiretroviral therapy (HAART) era...
  13. pmc A comparison of ad hoc methods to account for non-cancer AIDS and deaths as competing risks when estimating the effect of HAART on incident cancer AIDS among HIV-infected men
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Clin Epidemiol 63:459-67. 2010
    ....
  14. pmc Reduced risk of prostate cancer in U.S. Men with AIDS
    Meredith S Shiels
    Infections and Immunoepidemiology Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 19:2910-5. 2010
    ..In the United States, prostate-specific antigen (PSA) screening is common and increases the detection of prostate cancer. We evaluated whether the prostate cancer deficit among men with AIDS reflects differential PSA screening...
  15. pmc Association of cigarette smoking, alcohol consumption, and physical activity with sex steroid hormone levels in US men
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Cancer Causes Control 20:877-86. 2009
    ....
  16. pmc Effect of HAART on incident cancer and noncancer AIDS events among male HIV seroconverters
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Room E7133, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 48:485-90. 2008
    ..To explore the impact of highly active antiretroviral therapy (HAART) on the prevention of AIDS-defining cancers relative to other AIDS-defining events...
  17. pmc Circulating inflammation markers and prospective risk for lung cancer
    Meredith S Shiels
    Affiliations of authors Infections and Immunoepidemiology Branch MSS, AH, EAE, JK, AKC, Biostatistics Branch RMP, HAK, and Genetic Epidemiology Branch NEC, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD HPV Immunology Laboratory, SAIC Frederick Inc, Frederick, MD TJK, gs, LAP Department of Statistics, Dongguk University, Seoul, Korea J HP
    J Natl Cancer Inst 105:1871-80. 2013
    ..Despite growing recognition of an etiologic role for inflammation in lung carcinogenesis, few prospective epidemiologic studies have comprehensively investigated the association of circulating inflammation markers with lung cancer...
  18. pmc Relationship of sex steroid hormones with bone mineral density (BMD) in a nationally representative sample of men
    Channing J Paller
    Department of Endocrinology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Clin Endocrinol (Oxf) 70:26-34. 2009
    ..We evaluated the association of serum total and free sex steroid hormones and SHBG with osteopaenia in a nationally representative sample of men aged 20-90 years...
  19. doi request reprint The risk of hepatocellular carcinoma among individuals with acquired immunodeficiency syndrome in the United States
    Vikrant V Sahasrabuddhe
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Cancer 118:6226-33. 2012
    ..Hepatocellular carcinoma (HCC) is a concern among individuals with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS)...
  20. doi request reprint Increased risk of stomach and esophageal malignancies in people with AIDS
    E Christina Persson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852 7234, USA
    Gastroenterology 143:943-950.e2. 2012
    ..We evaluated the risks of different histologic and anatomic subtypes of carcinomas and non-Hodgkin lymphomas (NHLs) of the stomach and esophagus in people with acquired immunodeficiency syndrome (AIDS)...
  21. pmc Association between sex steroid hormones and hematocrit in a nationally representative sample of men
    Channing J Paller
    Sidney Kimmel Comprehensive Cancer Center and the Department of Epidemiology, Bloomberg School ofPublic Health, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Androl 33:1332-41. 2012
    ..Thus, changes in sex hormone levels with aging may contribute to the increased prevalence of anemia and thromboembolic stroke in men as they age...
  22. pmc Sarcomas other than Kaposi sarcoma occurring in immunodeficiency: interpretations from a systematic literature review
    Kishor Bhatia
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Curr Opin Oncol 24:537-46. 2012
    ..For comparison, we assessed sarcomas in the U.S. general population using Surveillance Epidemiology End Results (SEER) data...
  23. pmc Long-term cancer risk among people diagnosed with AIDS during childhood
    Edgar P Simard
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7076, Rockville, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 21:148-54. 2012
    ..Highly active antiretroviral therapy (HAART) results in partial immune restoration for people with AIDS, but its impact on cancer risk among children is unknown...
  24. doi request reprint Epidemiologic contributions to recent cancer trends among HIV-infected people in the United States
    Hilary A Robbins
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    AIDS 28:881-90. 2014
    ..g. age distribution), general population (background) cancer rates, and HIV-associated relative risks. We assessed the contributions of these factors to time trends for 10 cancers during 1996-2010...
  25. pmc A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A)
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Prev Med 47:116-22. 2008
    ..The association between common polymorphisms of these genes and smoking behavior was assessed among 10,059 Caucasian volunteers in Washington County, MD in 1989...
  26. pmc Disparities in the treatment and outcomes of lung cancer among HIV-infected individuals
    Gita Suneja
    Department of Radiation Oncology, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    AIDS 27:459-68. 2013
    ..It is unclear whether HIV-infected individuals with lung cancer receive similar cancer treatment as HIV-uninfected individuals...
  27. pmc The association of urinary cadmium with sex steroid hormone concentrations in a general population sample of US adult men
    Andy Menke
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA
    BMC Public Health 8:72. 2008
    ..Studies investigating the association of cadmium and sex steroid hormones in men have been inconsistent, but previous studies were relatively small...