Min Shi

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study
    Jinsil Kim
    Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA
    BMC Med Genet 14:77. 2013
  2. pmc Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts
    Min Shi
    Biostatistics Branch, NIEHS NIH, Durham, North Carolina, USA
    Am J Med Genet A 158:784-94. 2012
  3. doi request reprint How much are we missing in SNP-by-SNP analyses of genome-wide association studies?
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Epidemiology 22:845-7. 2011
  4. pmc Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans
    Hao Wu
    Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    J Allergy Clin Immunol 125:321-327.e13. 2010
  5. pmc Using imputed genotypes for relative risk estimation in case-parent studies
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Am J Epidemiol 173:553-9. 2011
  6. pmc Identification of microdeletions in candidate genes for cleft lip and/or palate
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Birth Defects Res A Clin Mol Teratol 85:42-51. 2009
  7. pmc Family-based gene-by-environment interaction studies: revelations and remedies
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Epidemiology 22:400-7. 2011
  8. pmc Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study
    Abee L Boyles
    Epidemiology Branch, NIEHS NIH, Durham, North Carolina 27709, USA
    Genet Epidemiol 33:247-55. 2009
  9. pmc The genetics of preterm birth: using what we know to design better association studies
    Clarice R Weinberg
    Biostatistics Branch, Mail Drop A3 03, National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 170:1373-81. 2009
  10. pmc Using case-parent triads to estimate relative risks associated with a candidate haplotype
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Ann Hum Genet 73:346-59. 2009

Collaborators

Detail Information

Publications17

  1. pmc Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study
    Jinsil Kim
    Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA
    BMC Med Genet 14:77. 2013
    ..Multiple lines of evidence suggest that genetic factors play an important role in its etiology. This study was designed to identify genetic variation associated with PTB in oxytocin pathway genes whose role in parturition is well known...
  2. pmc Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts
    Min Shi
    Biostatistics Branch, NIEHS NIH, Durham, North Carolina, USA
    Am J Med Genet A 158:784-94. 2012
    ..Thus, the most promising SNPs identified by this study may still be worth further investigation...
  3. doi request reprint How much are we missing in SNP-by-SNP analyses of genome-wide association studies?
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Epidemiology 22:845-7. 2011
    ..These examples highlight the need for better methods for gene-by-environment and gene-by-gene analyses...
  4. pmc Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans
    Hao Wu
    Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    J Allergy Clin Immunol 125:321-327.e13. 2010
    ..However, many have not been systematically replicated in human populations, especially those containing a large number of tagging single nucleotide polymorphisms (SNPs)...
  5. pmc Using imputed genotypes for relative risk estimation in case-parent studies
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Am J Epidemiol 173:553-9. 2011
    ..This method should be useful to investigators who wish to conduct meta-analyses using imputed SNP data from both case-parent triad and case-control studies...
  6. pmc Identification of microdeletions in candidate genes for cleft lip and/or palate
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Birth Defects Res A Clin Mol Teratol 85:42-51. 2009
    ..The panels used for such analyses can detect single nucleotide polymorphisms and copy number variants, both of which may help to identify small deleted regions of the genome that may contribute to a particular disease...
  7. pmc Family-based gene-by-environment interaction studies: revelations and remedies
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Epidemiology 22:400-7. 2011
    ..We also use simulations to assess the power for detecting interaction across a range of scenarios, designs, and analytic methods...
  8. pmc Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study
    Abee L Boyles
    Epidemiology Branch, NIEHS NIH, Durham, North Carolina 27709, USA
    Genet Epidemiol 33:247-55. 2009
    ..Despite strong evidence for genetic causes of oral facial clefts and the protective effects of maternal vitamins, we found no convincing indication that polymorphisms in these vitamin metabolism genes play an etiologic role...
  9. pmc The genetics of preterm birth: using what we know to design better association studies
    Clarice R Weinberg
    Biostatistics Branch, Mail Drop A3 03, National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 170:1373-81. 2009
    ..Both designs offer important advantages over the commonly applied case-mother/control-mother design...
  10. pmc Using case-parent triads to estimate relative risks associated with a candidate haplotype
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Ann Hum Genet 73:346-59. 2009
    ..To illustrate, we reanalyze data from a study of orofacial clefts to investigate a 9-SNP candidate haplotype of the IRF6 gene...
  11. pmc A sibling-augmented case-only approach for assessing multiplicative gene-environment interactions
    Clarice R Weinberg
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 174:1183-9. 2011
    ..They also show that robust analyses of interactions using tetrads or disease-discordant sibling pairs are equivalent to analyses using the SACO design...
  12. pmc Testing haplotype-environment interactions using case-parent triads
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Hum Hered 70:23-33. 2010
    ..We propose a procedure that uses case-parent triad data and, though not fully robust, resists bias from population structure...
  13. pmc An exploratory analysis on gene-environment interactions for Parkinson disease
    Jianjun Gao
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neurobiol Aging 33:2528.e1-6. 2012
    ..This study provides preliminary evidence of a potential gene-environment interaction for PD, which should be investigated in future studies...
  14. pmc Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects
    Min Shi
    Biostatistics Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA
    Birth Defects Res C Embryo Today 84:16-29. 2008
    ..As samples and data become increasingly available, more effort is needed in designing innovative analytical methods to study gene-environment interactions...
  15. pmc Case-sibling studies that acknowledge unstudied parents and permit the inclusion of unmatched individuals
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
    Int J Epidemiol 42:298-307. 2013
    ..Analysis typically accounts for within-family dependencies by using conditional logistic regression (CLR)...
  16. pmc Identification of risk-related haplotypes with the use of multiple SNPs from nuclear families
    Min Shi
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Am J Hum Genet 81:53-66. 2007
    ..As an illustration, we reanalyze data from a previously reported orofacial cleft study, to now investigate both fetal and maternal effects of the IRF6 gene...
  17. pmc Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children
    Dana B Hancock
    Department of Health and Human Services, Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
    PLoS Genet 5:e1000623. 2009
    ....