Research Topics
| L SherSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The role of genetic factors in the etiology of seasonal affective disorder and seasonalityL Sher
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
J Affect Disord 53:203-10. 1999..Future research may clarify the role of different genes in the development of SAD...
Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/AM A Enoch
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
Mol Psychiatry 4:89-92. 1999..However, these results should be treated with caution until replicated because of the possibility of false-positive findings in case-control association studies...
Evidence from the waking electroencephalogram that short sleepers live under higher homeostatic sleep pressure than long sleepersD Aeschbach
Section on Biological Rhythms, Intramural Research Program, National Institute of Mental Health, Bethesda, MD 20892, USA
Neuroscience 102:493-502. 2001..The homeostat-independent enhancement of theta/low-frequency alpha activity in the waking electroencephalogram in the short sleepers may be genetically determined or be the result of long-term adaptation to chronically short sleep...
Genetic studies of seasonal affective disorder and seasonalityL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD, USA
Compr Psychiatry 42:105-10. 2001..Vulnerability to SAD and disease pathology may be influenced by many genes, perhaps on several chromosomes...
Pleiotropy of the serotonin transporter gene for seasonality and neuroticismL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, Maryland, USA
Psychiatr Genet 10:125-30. 2000..Sibling-pair analysis confirmed that the effects of the 5-HTTLPR are due to genetic pleiotropy rather than population stratification...
Early response to light therapy partially predicts long-term antidepressant effects in patients with seasonal affective disorderL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD, USA
J Psychiatry Neurosci 26:336-8. 2001..To determine if the antidepressant effect of 1 hour of light therapy is predictive of the response after 1 and 2 weeks of treatment in patients with seasonal affective disorder (SAD)...
Free thyroxine and thyroid-stimulating hormone levels in patients with seasonal affective disorder and matched controlsL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
J Affect Disord 56:195-9. 1999..Future research will be needed to determine whether the difference in thyroid function between SAD patients and controls is an epiphenomenon or is related to the biological mechanisms that cause symptoms of SAD...
A circadian signal of change of season in patients with seasonal affective disorderT A Wehr
Section o Biological Rhythms, Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-1390, USA
Arch Gen Psychiatry 58:1108-14. 2001....
