Philip Shaw

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Intelligence and the developing human brain
    Philip Shaw
    10 Center Drive, 3N202, Child Psychiatry Branch, NIMH, Bethesda, Maryland 20892 1600, USA
    Bioessays 29:962-73. 2007
  2. pmc Trajectories of anatomic brain development as a phenotype
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch NIMH, 10 Center Drive, MSC 1367 Bethesda, MD 20892, USA
    Novartis Found Symp 289:101-12; discussion 112-8, 193-5. 2008
  3. pmc Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 66:888-96. 2009
  4. doi request reprint Development of cortical surface area and gyrification in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 72:191-7. 2012
  5. ncbi request reprint A prospective study of the effects of anterior temporal lobectomy on emotion recognition and theory of mind
    P Shaw
    Section of Cognitive Neuropsychiatry, Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Neuropsychologia 45:2783-90. 2007
  6. pmc Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation
    P Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Room 3N202, Building 10, Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:19649-54. 2007
  7. ncbi request reprint Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Room 3N202, Bldg 10, Center Drive, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 64:921-31. 2007
  8. ncbi request reprint Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    Lancet Neurol 6:494-500. 2007
  9. pmc Psychostimulant treatment and the developing cortex in attention deficit hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Bldg 10, Center Dr, NIMH, Bethesda, MD 20892, USA
    Am J Psychiatry 166:58-63. 2009
  10. ncbi request reprint Decision making about children with psychotic symptoms: using the best evidence in choosing a treatment
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20932 1600, USA
    J Am Acad Child Adolesc Psychiatry 45:1381-6. 2006

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Intelligence and the developing human brain
    Philip Shaw
    10 Center Drive, 3N202, Child Psychiatry Branch, NIMH, Bethesda, Maryland 20892 1600, USA
    Bioessays 29:962-73. 2007
    ..A major future challenge is to determine the cellular events that underpin the neuroanatomic differences correlated with intelligence...
  2. pmc Trajectories of anatomic brain development as a phenotype
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch NIMH, 10 Center Drive, MSC 1367 Bethesda, MD 20892, USA
    Novartis Found Symp 289:101-12; discussion 112-8, 193-5. 2008
    ....
  3. pmc Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 66:888-96. 2009
    ..No study has examined the development of cortical asymmetry using longitudinal neuroanatomical data...
  4. doi request reprint Development of cortical surface area and gyrification in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 72:191-7. 2012
    ..We previously found that ADHD is characterized by a delayed maturation of prefrontal cortical thickness. We now ask if this extends to the maturation of cortical surface area and gyrification...
  5. ncbi request reprint A prospective study of the effects of anterior temporal lobectomy on emotion recognition and theory of mind
    P Shaw
    Section of Cognitive Neuropsychiatry, Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Neuropsychologia 45:2783-90. 2007
    ..The finding complements earlier demonstrations that damage to the right amygdala is associated with impaired processing of fear; amelioration of right amygdala function may conversely be associated with an improvement...
  6. pmc Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation
    P Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Room 3N202, Building 10, Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:19649-54. 2007
    ..Neuroanatomic documentation of a delay in regional cortical maturation in ADHD has not been previously reported...
  7. ncbi request reprint Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Room 3N202, Bldg 10, Center Drive, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 64:921-31. 2007
    ..Attention-deficit/hyperactivity disorder (ADHD) is one of the most heritable neuropsychiatric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently implicated in its pathogenesis...
  8. ncbi request reprint Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    Lancet Neurol 6:494-500. 2007
    ....
  9. pmc Psychostimulant treatment and the developing cortex in attention deficit hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Bldg 10, Center Dr, NIMH, Bethesda, MD 20892, USA
    Am J Psychiatry 166:58-63. 2009
    ..The authors sought to determine prospectively whether psychostimulant treatment for attention deficit hyperactivity disorder (ADHD) was associated with differences in the development of the cerebral cortex during adolescence...
  10. ncbi request reprint Decision making about children with psychotic symptoms: using the best evidence in choosing a treatment
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20932 1600, USA
    J Am Acad Child Adolesc Psychiatry 45:1381-6. 2006
  11. ncbi request reprint Childhood-onset schizophrenia: A double-blind, randomized clozapine-olanzapine comparison
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1500, USA
    Arch Gen Psychiatry 63:721-30. 2006
    ..The psychiatrist has a limited evidence base to guide treatment, particularly as there are no trials in children comparing atypical antipsychotics, the mainstay of current treatment...
  12. ncbi request reprint Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1500, USA
    Arch Gen Psychiatry 63:540-9. 2006
    ..Data from a previous prospective study of lobar volumes in children with attention-deficit/hyperactivity disorder (ADHD) are reexamined using a measure of cortical thickness...
  13. pmc Cortical development in typically developing children with symptoms of hyperactivity and impulsivity: support for a dimensional view of attention deficit hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Am J Psychiatry 168:143-51. 2011
    ....
  14. doi request reprint Childhood psychiatric disorders as anomalies in neurodevelopmental trajectories
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Hum Brain Mapp 31:917-25. 2010
    ..Again taking ADHD as an example, we found that remission is associated with convergence to the template of typical development, whereas persistence is accompanied by progressive divergence away from typical trajectories...
  15. ncbi request reprint New insights into attention-deficit/hyperactivity disorder using structural neuroimaging
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Room 3N202, Building 10, Center Drive, Bethesda, MD 20892, USA
    Curr Psychiatry Rep 11:393-8. 2009
    ..Finally, longitudinal data suggest that ADHD in childhood may be characterized by a delay in cortical maturation and that different clinical outcomes may be associated with different developmental trajectories in adolescence and beyond...
  16. ncbi request reprint Differential effects of lesions of the amygdala and prefrontal cortex on recognizing facial expressions of complex emotions
    P Shaw
    Institute of Psychiatry, London
    J Cogn Neurosci 17:1410-9. 2005
    ..The results also suggest that the amygdala has a role in processing a wide range of emotional expressions...
  17. ncbi request reprint Intellectual ability and cortical development in children and adolescents
    P Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20182, USA
    Nature 440:676-9. 2006
    ..This study indicates that the neuroanatomical expression of intelligence in children is dynamic...
  18. doi request reprint Neurodevelopmental trajectories of the human cerebral cortex
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:3586-94. 2008
    ....
  19. ncbi request reprint Childhood onset schizophrenia: cortical brain abnormalities as young adults
    Deanna Greenstein
    Child Psychiatry Branch, NIMH NIH, Bethesda, MD 20892, USA
    J Child Psychol Psychiatry 47:1003-12. 2006
    ....
  20. pmc Developmental trajectories of the corpus callosum in attention-deficit/hyperactivity disorder
    Mary Gilliam
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 69:839-46. 2011
    ..Using longitudinal data, we tested the hypothesis that there would be a congruent disruption in the growth of the anterior corpus callosum, which contains white matter tracts connecting prefrontal cortical regions...
  21. doi request reprint Relationship between post-operative depression/anxiety and hippocampal/amygdala volumes in temporal lobectomy for epilepsy
    Thomas Paparrigopoulos
    Section of Cognitive Neuropsychiatry, Institute of Psychiatry, King s College London, DeCrespigny Park, London, United Kingdom
    Epilepsy Res 81:30-5. 2008
    ..The objective of the study was to investigate the relationship between post-operative depressive/anxiety symptoms and hippocampal/amygdala volumes following anterior temporal lobectomy...
  22. pmc Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth
    Gregory L Wallace
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland 20892 1366, USA
    J Neurosci 32:4856-60. 2012
    ..These results support the dimensional view of psychopathology and provide neural signatures that can serve as informative endophenotypes for future genetic studies...
  23. ncbi request reprint IQ stabilization in childhood-onset schizophrenia
    Peter A Gochman
    Child Psychiatry Branch, NIMH Bldg 10, Rm 3N202 Bethesda, MD 20892 1600, USA
    Schizophr Res 77:271-7. 2005
    ..To examine the long term IQ trajectory for childhood-onset schizophrenia (COS) in an expanded, prospective longitudinal study...
  24. ncbi request reprint A critical period for the impact of amygdala damage on the emotional enhancement of memory?
    P Shaw
    Department of Psychological Medicine, Institute of Psychiatry, PO Box 68, De Crespigny Park, London SE5 8AF, UK
    Neurology 65:326-8. 2005
    ..This adds to evidence for an early critical period in the development of amygdala function...
  25. ncbi request reprint Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories
    A M Addington
    Child Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892, USA
    Mol Psychiatry 12:195-205. 2007
    ..This replication further documents the role of NRG1 in the abnormal brain development in schizophrenia. This is the first demonstration of a disease-specific pattern of gene action in schizophrenia...
  26. ncbi request reprint The impact of early and late damage to the human amygdala on 'theory of mind' reasoning
    P Shaw
    Section of Cognitive Neuropsychiatry, Department of Psychological Medicine, Centre for Neuroscience Research, King s College, London, UK
    Brain 127:1535-48. 2004
    ..We conclude that the amygdala may play an important role in the neural systems supporting the normal development of ToM reasoning...
  27. doi request reprint Empathy and enduring depersonalization: the role of self-related processes
    Emma J Lawrence
    Section of Cognitive Neuropsychiatry, Department of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Soc Neurosci 2:292-306. 2007
    ..These findings suggest affective empathy to be reliant on intact emotional experience in the observer. In addition, excessive self-focus may be detrimental to an empathic response...
  28. ncbi request reprint Quantitative magnetic resonance imaging of the amygdala in temporal lobe epilepsy-clinico-pathological correlations (a pilot study)
    Michelle V Lambert
    Section of Cognitive Neuropsychiatry, Department of Psychological Medicine, Institute of Psychiatry, GKT School of Medicine, and King s College Hospital, DeCrespigny Park, SE5 8AF, London, UK
    Epilepsy Res 53:39-46. 2003
    ..We wished to explore whether amygdala volume correlated with pre-operative clinical variables and post-operative outcome...
  29. ncbi request reprint Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): an update
    M C Gornick
    Child Psychiatry Branch, NIMH, NIH, Bethesda, Maryland 20892 1600, USA
    Am J Med Genet B Neuropsychiatr Genet 144:379-82. 2007
    ..This provides further evidence of the role of the DRD4 7-repeat allele in the etiology of ADHD and suggests that this allele may be associated with a more benign form of the disorder...
  30. pmc No: it is dangerous to ask psychiatrists to enforce social policy
    Gavin Yamey
    Institute of Psychiatry, London, UK
    West J Med 176:5. 2002
  31. ncbi request reprint The human amygdala: a systematic review and meta-analysis of volumetric magnetic resonance imaging
    B Brierley
    Section of Cognitive Neuropsychiatry, Institute of Psychiatry, DeCrespigny Park, London SE5 8AF, UK
    Brain Res Brain Res Rev 39:84-105. 2002
    ..This work should guide future research in obtaining accurate and reliable amygdala volume measures which in turn will aid comparisons with clinical groups and the specification of structural-functional relationships...
  32. ncbi request reprint Cerebellar development and clinical outcome in attention deficit hyperactivity disorder
    Susan Mackie
    Columbia University School of Medicine, New York, NY, USA
    Am J Psychiatry 164:647-55. 2007
    ....
  33. doi request reprint Defining the contribution of genetic risk to structural and functional anomalies in ADHD
    Judith L Rapoport
    J Am Acad Child Adolesc Psychiatry 47:2-3. 2008