Y Sharabi

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Susceptibility of the influence of weight on blood pressure in men versus women: lessons from a large-scale study of young adults
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke NIH, 10 Center Drive, MSC 1620, Building 10, Room 6N252, Bethesda, MD 20892 1620, USA
    Am J Hypertens 17:404-8. 2004
  2. ncbi request reprint Sleep apnea as a risk factor for hypertension
    Yehonatan Sharabi
    Hypertension Unit, Chaim Sheba Medical Center, Tel Hashomer Sackler School of Medicine, Tel Aviv University, Israel
    Curr Opin Nephrol Hypertens 13:359-64. 2004
  3. ncbi request reprint Glucagon does not affect catecholamine release in primary cultures of bovine adrenal chromaffin cells
    Y Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1620, USA
    Horm Metab Res 37:205-8. 2005
  4. ncbi request reprint Baroreflex failure as a late sequela of neck irradiation
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Hypertension 42:110-6. 2003
  5. ncbi request reprint Cigarette smoking and hearing loss: lessons from the young adult periodic examinations in Israel (YAPEIS) database
    Yehonatan Sharabi
    Staff Periodic Examination Center, and Israel Defense Forces Medical Corps, Israel
    Isr Med Assoc J 4:1118-20. 2002
  6. ncbi request reprint Neuropharmacologic distinction of neurogenic orthostatic hypotension syndromes
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Clin Neuropharmacol 29:97-105. 2006
  7. doi request reprint The effect of chronic hyperinsulinemia on plasma adiponectin levels in Sprague-Dawley rats
    Y Kamari
    Hypertension Unit and Internal Medicine D, The Chaim Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Metab Res 41:46-9. 2009
  8. ncbi request reprint Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension
    D S Goldstein
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1620, USA
    Neurology 60:1327-32. 2003
  9. ncbi request reprint Neurotransmitter specificity of sympathetic denervation in Parkinson's disease
    Y Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Neurology 60:1036-9. 2003
  10. ncbi request reprint Reproducibility of exaggerated blood pressure response to exercise in healthy patients
    Y Sharabi
    Internal Medicine D, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am Heart J 141:1014-7. 2001

Detail Information

Publications40

  1. ncbi request reprint Susceptibility of the influence of weight on blood pressure in men versus women: lessons from a large-scale study of young adults
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke NIH, 10 Center Drive, MSC 1620, Building 10, Room 6N252, Bethesda, MD 20892 1620, USA
    Am J Hypertens 17:404-8. 2004
    ..Weight and blood pressure (BP) are closely related. The aim of this study was to quantify this relationship and compare it to other factors in a population of relatively young adults, with particular focus on the possible role of gender...
  2. ncbi request reprint Sleep apnea as a risk factor for hypertension
    Yehonatan Sharabi
    Hypertension Unit, Chaim Sheba Medical Center, Tel Hashomer Sackler School of Medicine, Tel Aviv University, Israel
    Curr Opin Nephrol Hypertens 13:359-64. 2004
    ....
  3. ncbi request reprint Glucagon does not affect catecholamine release in primary cultures of bovine adrenal chromaffin cells
    Y Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1620, USA
    Horm Metab Res 37:205-8. 2005
    ..In this study, we tested whether the catecholamine secretory response to glucagon was present in bovine chromaffin cells or exclusive to the tumor cells...
  4. ncbi request reprint Baroreflex failure as a late sequela of neck irradiation
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Hypertension 42:110-6. 2003
    ..Splinting of carotid sinus mechanoreceptors in rigidified arterial walls would impede detection of alterations in blood pressure and thereby disrupt baroreflex regulation of cardiovagal and sympathetic outflows...
  5. ncbi request reprint Cigarette smoking and hearing loss: lessons from the young adult periodic examinations in Israel (YAPEIS) database
    Yehonatan Sharabi
    Staff Periodic Examination Center, and Israel Defense Forces Medical Corps, Israel
    Isr Med Assoc J 4:1118-20. 2002
    ..Some studies have indicated a possible link between cigarette smoking and hearing loss...
  6. ncbi request reprint Neuropharmacologic distinction of neurogenic orthostatic hypotension syndromes
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Clin Neuropharmacol 29:97-105. 2006
    ....
  7. doi request reprint The effect of chronic hyperinsulinemia on plasma adiponectin levels in Sprague-Dawley rats
    Y Kamari
    Hypertension Unit and Internal Medicine D, The Chaim Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Metab Res 41:46-9. 2009
    ..These results support the concept that the primary defect that results in insulin resistance and hyperinsulinemia is responsible for the altered plasma adiponectin levels in the metabolic syndrome and type 2 diabetes...
  8. ncbi request reprint Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension
    D S Goldstein
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1620, USA
    Neurology 60:1327-32. 2003
    ..From the concept of a unitary sympathoadrenomedullary system, one might predict parallel sympathoneural and adrenomedullary abnormalities in NOH...
  9. ncbi request reprint Neurotransmitter specificity of sympathetic denervation in Parkinson's disease
    Y Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Neurology 60:1036-9. 2003
    ..All 12 had normal QSART results. The sympathetic nervous system lesion in PD involves loss of postganglionic catecholaminergic but not cholinergic nerves...
  10. ncbi request reprint Reproducibility of exaggerated blood pressure response to exercise in healthy patients
    Y Sharabi
    Internal Medicine D, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am Heart J 141:1014-7. 2001
    ..The aim of this study was to test the reproducibility over time of ExBPR and to better characterize patients who consistently respond in this manner...
  11. ncbi request reprint Homocysteine levels in hypertensive patients with a history of cardiac or cerebral atherothrombotic events
    Y Sharabi
    Internal Medicine D, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Hypertens 12:766-71. 1999
    ..Thus, hyperhomocysteinemia is not a feature of hypertensive patients with atherothrombotic events and there is no support for additive or synergistic effects between these two independent risk factors...
  12. ncbi request reprint Metabolic stress with a high carbohydrate diet increases adiponectin levels
    Y Kamari
    Hypertension Unit, Chaim Sheba Medical Center, Tel Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Metab Res 39:384-8. 2007
    ..Therefore, we studied the effect of high-carbohydrate diet on adiponectin levels in the rat models of hypertension and insulin resistance...
  13. ncbi request reprint Natural suppressor cells in spleens of irradiated, bone marrow-reconstituted mice and normal bone marrow: lack of Sca-1 expression and enrichment by depletion of Mac1-positive cells
    M Sykes
    Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892
    Cell Immunol 127:260-74. 1990
    ..In contrast, we report here that depletion of Sca1-positive pluripotent hematopoietic stem cells with monoclonal antibody plus immunomagnetic beads does not remove NS activity...
  14. ncbi request reprint Does acetylcholinesterase inhibition affect catecholamine secretion by adrenomedullary cells?
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Isr Med Assoc J 6:396-9. 2004
    ..Splanchnic nerve stimulation evokes adrenomedullary catecholamine secretion via acetylcholine release and occupation of nicotinic cholinergic receptors on chromaffin cells...
  15. ncbi request reprint Neurocirculatory abnormalities in Parkinson disease with orthostatic hypotension: independence from levodopa treatment
    David S Goldstein
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Hypertension 46:1333-9. 2005
    ..Parkinson disease with orthostatic hypotension features reflexive cardiovagal and sympathoneural failure and cardiac and partial extracardiac sympathetic denervation, independent of levodopa treatment...
  16. ncbi request reprint Cardiac sympathetic denervation preceding motor signs in Parkinson disease
    David S Goldstein
    Clinical Neurocardiology Section, NINDS, NIH, Bethesda, MD 20892 1620, USA
    Clin Auton Res 17:118-21. 2007
    ..The results lead us to hypothesize that cardiac noradrenergic denervation and decreased baroreflex-cardiovagal function may occur early in the pathogenesis of PD...
  17. ncbi request reprint The prevalence of erectile dysfunction among hypertensive and prehypertensive men aged 25-40 years
    Rafi J Heruti
    Reuth Medical Center Rehabilitation, Tel Aviv, Israel
    J Sex Med 4:596-601. 2007
    ..Erectile dysfunction (ED) and hypertension (HTN) are common and associated among men aged 40-70 years. Data on the prevalence of ED among younger hypertensive and prehypertensive men are limited...
  18. ncbi request reprint Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes
    David S Goldstein
    Clinical Neurocardiology Section, NINDS, NIH, USA
    Circulation 106:2358-65. 2002
    ..Whether these conditions involve abnormal cardiac sympathetic innervation or function has been unclear...
  19. ncbi request reprint Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma
    Yehonatan Sharabi
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Hypertens 25:2286-95. 2007
    ..We therefore examined sympathoadrenal function in patients with pseudopheochromocytoma compared with age-matched control subjects in whom there was no suspicion of pheochromocytoma...
  20. ncbi request reprint Relative impact of socioeconomic status on blood pressure lessons from a large-scale survey of young adults
    Itamar Grotto
    Department of Epidemiology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Am J Hypertens 20:1140-5. 2007
    ..We aimed to assess the influence of SES on blood pressure in a large population of young adults...
  21. pmc Supine low-frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation
    Jeffrey P Moak
    Children s National Medical Center, Washington, DC, USA
    Heart Rhythm 4:1523-9. 2007
    ..Alternatively, LF power might reflect baroreflexive modulation of autonomic outflows...
  22. doi request reprint Central dopamine deficiency in pure autonomic failure
    David S Goldstein
    Clinical Neurocardiology Section, NINDS, NIH, Bethesda, MD 20892 1620, USA
    Clin Auton Res 18:58-65. 2008
    ..A patient with PAF and another with PD had rapid postmortem striatal, nigral, and sympathetic ganglion sampling, with assays of catechols and tyrosine hydroxylase activity...
  23. doi request reprint Cardiac sympathetic hypo-innervation in familial dysautonomia
    David S Goldstein
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, NIH, 10 Center Drive MSC 1620, Building 10 Room 6N252, Bethesda, MD 20892 1620, USA
    Clin Auton Res 18:115-9. 2008
    ..Whether such loss extends to sympathetic innervation of the heart has been unknown. This study used 6-[(18)F]fluorodopamine neuroimaging to assess cardiac sympathetic innervation and function in FD...
  24. ncbi request reprint Diastolic blood pressure is the first to rise in association with early subclinical obstructive sleep apnea: lessons from periodic examination screening
    Yehonatan Sharabi
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Hypertens 16:236-9. 2003
    ..We conducted a case-control study in which we analyzed the clinical characteristics of young adults who underwent a periodic health examination and were screened for, and eventually found to experience, OSAS...
  25. ncbi request reprint Prevalence of prehypertension and associated cardiovascular risk profiles among young Israeli adults
    Itamar Grotto
    Department of Epidemiology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Hypertension 48:254-9. 2006
    ..Our findings support the recommendation of lifestyle modification for prehypertensive patients. Further prospective studies are required to determine the role of pharmacotherapy in prehypertension...
  26. ncbi request reprint Coronary vascular resistance in primary chronic autonomic failure
    Sheng Ting Li
    Clin Auton Res 16:293-5. 2006
    ..Cardiac sympathetic outflow does not seem to contribute to coronary vascular resistance...
  27. ncbi request reprint Neurocirculatory abnormalities in chronic orthostatic intolerance
    David S Goldstein
    Clinical Neurocardiology Section, NINDS, National Institutes of Health, Bethesda, MD, USA
    Circulation 111:839-45. 2005
    ..This study addressed whether patients with COI and POTS or NCS have neurocirculatory abnormalities during supine rest...
  28. ncbi request reprint Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans
    Alexander Neumeister
    Mood and Anxiety Disorders Program, Section on Experimental Therapeutics and Pathophysiology, NIMH, NIH, Bethesda, MD, USA
    Pharmacogenet Genomics 15:143-9. 2005
    ..In-frame deletion of the alpha2C-adrenoreceptor subtype (alpha2CDel322-325) increases the risk of congestive heart failure. Increased delivery of catecholamines to cardiovascular receptors might explain this increased risk...
  29. ncbi request reprint Plasma catecholamines and blood volume in native Andeans during hypoxia and normoxia
    Alfredo Gamboa
    Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21st Avenue South, Suite AA3228, Nashville, TN 37232, USA
    Clin Auton Res 16:40-5. 2006
    ..05); red cell volume was higher in HA only in the CMS group. The results indicate sympathetic nervous stimulation by chronic ambient hypoxia at altitude in Andean natives, independent of maladaptation to their native environment...
  30. ncbi request reprint Association between supine hypertension and orthostatic hypotension in autonomic failure
    David S Goldstein
    the Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Hypertension 42:136-42. 2003
    ..The finding of lower plasma NE levels in patients with than without supine hypertension suggests involvement of pressor mechanisms independent of the sympathetic nervous system...
  31. ncbi request reprint Enzyme replacement therapy improves peripheral nerve and sweat function in Fabry disease
    Raphael Schiffmann
    Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke National Institutes of Health, Building 10, Room 3D03, 9000 Rockville Pike, Bethesda, MD 20892 1260, USA
    Muscle Nerve 28:703-10. 2003
    ..QSART may be useful to further optimize the dose and frequency of ERT...
  32. pmc Dopamine contamination of infused tyramine
    Courtney Holmes
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1620, USA
    Clin Chem 51:1733-5. 2005
  33. doi request reprint Hypertension and socioeconomic status
    Itamar Grotto
    Department of Epidemiology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Curr Opin Cardiol 23:335-9. 2008
    ..We also review several mechanisms through which the effects of socioeconomic status on hypertension may be mediated...
  34. doi request reprint Effect of telmisartan, angiotensin II receptor antagonist, on metabolic profile in fructose-induced hypertensive, hyperinsulinemic, hyperlipidemic rats
    Yehuda Kamari
    Hypertension Unit, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Hypertens Res 31:135-40. 2008
    ....
  35. ncbi request reprint Sleep apnea-induced hypertension: mechanisms of vascular changes
    Yehonatan Sharabi
    Department of Internal Medicine D, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Expert Rev Cardiovasc Ther 3:937-40. 2005
    ..This review will clarify the unique set of features of hypertension associated with obstructive sleep apnea and examine the mechanisms that contribute to its cardiovascular consequences...
  36. ncbi request reprint Antianxiety treatment in patients with excessive hypertension
    Ehud Grossman
    Internal Medicine D and the Hypertension Unit, The Chaim Sheba Medical Center, Tel Aviv University, Sackler School of Medicine, Tel Hashomer 52621, Israel
    Am J Hypertens 18:1174-7. 2005
    ..We therefore compared the efficacy and safety of antianxiety treatment with sublingual captopril administration in patients with excessive hypertension and no evidence of acute target organ damage...
  37. ncbi request reprint Effect of PPAR-gamma agonist on adiponectin levels in the metabolic syndrome: lessons from the high fructose fed rat model
    Yehonatan Sharabi
    Hypertension Unit, C Sheba Medical Center, Tel Hashomer, Israel
    Am J Hypertens 20:206-10. 2007
    ..We studied the effect of the PPAR-gamma agonist rosiglitazone on adiponectin and the metabolic profile in the fructose-induced hypertensive, hyperinsulinemic, hypertriglyceridemic rat model...
  38. ncbi request reprint Melatonin reduces night blood pressure in patients with nocturnal hypertension
    Ehud Grossman
    Department of Internal Medicine D and Hypertension Unit, The Chaim Sheba Medical Center, Tel Hashomer, Affiliated with Sackler School of Medicine, Tel Aviv University, Israel
    Am J Med 119:898-902. 2006
    ..We therefore studied the potency of melatonin to reduce nighttime blood pressure (BP) in treated hypertensive patients with nocturnal hypertension...
  39. ncbi request reprint Eosinophilia, myositis, and myasthenia gravis associated with a thymoma
    Irit Avni
    Internal Medicine D, Sheba Medical Center, Tel Hashomer, 52621, Israel
    Muscle Nerve 34:242-5. 2006
    ..Thymoma-associated T-cell abnormalities may well have contributed to this rare association. This case underscores the need to reevaluate constantly the presumed cause of clinical complaints, as more than one cause may be present...
  40. ncbi request reprint Efficacy of add-on aldosterone receptor blocker in uncontrolled hypertension
    Yehonatan Sharabi
    Hypertension Unit and Internal Medicine D, Chaim Sheba Medical affiliated to the Chaim Sheba Medical Center, Tel Hashomer
    Am J Hypertens 19:750-5. 2006
    ..The purpose of this study was to evaluate the efficacy of this approach and to characterize those who respond effectively to an add-on aldosterone antagonist...