Efe Sezgin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA
    Am J Ophthalmol 151:999-1006.e4. 2011
  2. pmc Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
    J Acquir Immune Defic Syndr 54:343-51. 2010
  3. pmc Effect of host genetics on the development of cytomegalovirus retinitis in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, Maryland 21702 1201, USA
    J Infect Dis 202:606-13. 2010
  4. pmc Examination of disease-based selection, demographic history and population structure in European Y-chromosome haplogroup I
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Hum Genet 55:613-20. 2010
  5. pmc Genome-wide association study implicates PARD3B-based AIDS restriction
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, Frederick, MD 21702, USA
    J Infect Dis 203:1491-502. 2011
  6. pmc Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA
    PLoS ONE 5:e12862. 2010
  7. pmc Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia
    Ping An
    Basic Research Laboratory, SAIC Frederick, National Cancer Institute Frederick, Frederick, Maryland, USA
    PLoS Genet 7:e1002328. 2011
  8. pmc Mitochondrial DNA haplogroups influence AIDS progression
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702 1201, USA
    AIDS 22:2429-39. 2008
  9. pmc The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove
    Minzhong Tang
    College of Life Science and Bio engineering, Beijing University of Technology, Beijing, China
    PLoS Genet 8:e1003103. 2012
  10. pmc Association of Y chromosome haplogroup I with HIV progression, and HAART outcome
    Efe Sezgin
    NCI Frederick, MD 21702, USA
    Hum Genet 125:281-94. 2009

Detail Information

Publications10

  1. pmc Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA
    Am J Ophthalmol 151:999-1006.e4. 2011
    ....
  2. pmc Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
    J Acquir Immune Defic Syndr 54:343-51. 2010
    ..Clearly, further studies are warrented...
  3. pmc Effect of host genetics on the development of cytomegalovirus retinitis in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, Maryland 21702 1201, USA
    J Infect Dis 202:606-13. 2010
    ..The ubiquitous CMV pathogen contains a human interleukin-10 (IL-10) homolog in its genome and utilizes it to evade host immune reactions through an IL-10 receptor mediated immune-suppression pathway...
  4. pmc Examination of disease-based selection, demographic history and population structure in European Y-chromosome haplogroup I
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Hum Genet 55:613-20. 2010
    ..Clearly, further studies on Y-chromosome candidate loci sequencing to discover functional variants and discern the roles of evolutionary factors are warranted...
  5. pmc Genome-wide association study implicates PARD3B-based AIDS restriction
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, Frederick, MD 21702, USA
    J Infect Dis 203:1491-502. 2011
    ..Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression...
  6. pmc Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA
    PLoS ONE 5:e12862. 2010
    ..Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroups with presumed functional differences have been associated with differential AIDS progression...
  7. pmc Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia
    Ping An
    Basic Research Laboratory, SAIC Frederick, National Cancer Institute Frederick, Frederick, Maryland, USA
    PLoS Genet 7:e1002328. 2011
    ..28-6.31) among four major AIDS-defining conditions. Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor may affect PCP through immune regulation and inducing inflammation...
  8. pmc Mitochondrial DNA haplogroups influence AIDS progression
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702 1201, USA
    AIDS 22:2429-39. 2008
    ....
  9. pmc The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove
    Minzhong Tang
    College of Life Science and Bio engineering, Beijing University of Technology, Beijing, China
    PLoS Genet 8:e1003103. 2012
    ....
  10. pmc Association of Y chromosome haplogroup I with HIV progression, and HAART outcome
    Efe Sezgin
    NCI Frederick, MD 21702, USA
    Hum Genet 125:281-94. 2009
    ..Our results suggest that one or more loci on the Y chromosome found on haplogroup Y-I have an effect on AIDS progression and treatment responses in European Americans...