Max A Seibold

Summary

Affiliation: National Jewish Medical and Research Center
Country: USA

Publications

  1. pmc Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein
    Max A Seibold
    Department of Medicine, Howard Hughes Medical Institute, University of California, San Francisco, California 94143, USA
    J Biol Chem 284:19650-8. 2009
  2. pmc An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity
    Max A Seibold
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 2911, USA
    Hum Mol Genet 17:2681-90. 2008
  3. pmc Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit
    Max A Seibold
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    J Allergy Clin Immunol 122:944-950.e3. 2008
  4. pmc Dissecting complex diseases in complex populations: asthma in latino americans
    Shweta Choudhry
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 2911, USA
    Proc Am Thorac Soc 4:226-33. 2007
  5. pmc The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation
    Anh L Innes
    The Cardiovascular Research Institute, University of California, San Francisco, California, USA
    Am J Respir Crit Care Med 183:189-94. 2011
  6. doi request reprint Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis
    Ivana V Yang
    Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA
    Thorax 68:1114-21. 2013

Detail Information

Publications6

  1. pmc Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein
    Max A Seibold
    Department of Medicine, Howard Hughes Medical Institute, University of California, San Francisco, California 94143, USA
    J Biol Chem 284:19650-8. 2009
    ..The structural, kinetic, and genetic data regarding the AMCase isoforms are consistent with the Th2-priming effects of environmental chitin and a role for AMCase in negatively regulating this stimulus...
  2. pmc An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity
    Max A Seibold
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 2911, USA
    Hum Mol Genet 17:2681-90. 2008
    ..Female asthmatics may be insulated from the deleterious effects of the 818T allele by estrogen-mediated upregulation in BK channel activity...
  3. pmc Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit
    Max A Seibold
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    J Allergy Clin Immunol 122:944-950.e3. 2008
    ..Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) have chitinolytic activity, but relatively little is known about their expression in human asthma...
  4. pmc Dissecting complex diseases in complex populations: asthma in latino americans
    Shweta Choudhry
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 2911, USA
    Proc Am Thorac Soc 4:226-33. 2007
    ....
  5. pmc The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation
    Anh L Innes
    The Cardiovascular Research Institute, University of California, San Francisco, California, USA
    Am J Respir Crit Care Med 183:189-94. 2011
    ..Acute asthma exacerbations, precipitated by viral infections, are a significant cause of morbidity, but not all patients with asthma are equally susceptible...
  6. doi request reprint Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis
    Ivana V Yang
    Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA
    Thorax 68:1114-21. 2013
    ..We hypothesised that gene expression profiles of lung tissue may identify molecular subtypes of disease that could classify subtypes of IPF/UIP that have clinical implications...