Yoshitatsu Sei

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Pentoxifylline decreases brain levels of platelet activating factor in murine AIDS
    Y Sei
    Laboratory of Neuroscience, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Eur J Pharmacol 325:81-4. 1997
  2. ncbi Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms
    Y Sei
    Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Mol Psychiatry 12:946-57. 2007
  3. ncbi Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models
    Yoshitatsu Sei
    Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 5:e10789. 2010
  4. ncbi A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine
    Yoshitatsu Sei
    Gastroenterology Section, DDB, National Institute of Diabetes, Digestive and Kidney Diseases, 10 Center Dr, Bldg 10, Rm 9C 112, MSC1804, Bethesda, MD 20892 1385, USA
    Am J Physiol Gastrointest Liver Physiol 300:G345-56. 2011
  5. ncbi The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells
    Alice P Liou
    Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Physiol Gastrointest Liver Physiol 300:G538-46. 2011
  6. ncbi Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
    Amanda J Law
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:12165-70. 2012
  7. ncbi Neuregulin-1 regulates cell adhesion via an ErbB2/phosphoinositide-3 kinase/Akt-dependent pathway: potential implications for schizophrenia and cancer
    Christopher G Kanakry
    Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 2:e1369. 2007
  8. ncbi The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin
    Alice P Liou
    Digestive Diseases Branch, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Gastroenterology 140:903-12. 2011
  9. ncbi DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
    Kenji Nakata
    Clinical Brain Disorders Branch, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Proc Natl Acad Sci U S A 106:15873-8. 2009
  10. ncbi LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor
    E Koustova
    Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases/NIH, Bethesda, Maryland 20892-0008, USA
    J Clin Invest 107:737-44. 2001

Collaborators

Detail Information

Publications20

  1. ncbi Pentoxifylline decreases brain levels of platelet activating factor in murine AIDS
    Y Sei
    Laboratory of Neuroscience, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Eur J Pharmacol 325:81-4. 1997
    ..62; P < 0.01). This study demonstrates that pentoxifylline treatment was effective in decreasing the levels of TNF-alpha in the serum and PAF levels in the brain of mice infected with the LP-BM5 MuLV...
  2. ncbi Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms
    Y Sei
    Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Mol Psychiatry 12:946-57. 2007
    ....
  3. ncbi Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models
    Yoshitatsu Sei
    Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 5:e10789. 2010
    ....
  4. ncbi A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine
    Yoshitatsu Sei
    Gastroenterology Section, DDB, National Institute of Diabetes, Digestive and Kidney Diseases, 10 Center Dr, Bldg 10, Rm 9C 112, MSC1804, Bethesda, MD 20892 1385, USA
    Am J Physiol Gastrointest Liver Physiol 300:G345-56. 2011
    ..Further investigation of the function of this subset may provide novel insights into the genesis and development of enteroendocrine cells as well as enteroendocrine tumorigenesis...
  5. ncbi The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells
    Alice P Liou
    Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Physiol Gastrointest Liver Physiol 300:G538-46. 2011
    ..The present data suggest that CaSR is required for hormone secretion in the specific response to L-Phe by the native I cell, and that a receptor-mediated mechanism may inhibit hormone secretion in the absence of a fully functional CaSR...
  6. ncbi Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
    Amanda J Law
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:12165-70. 2012
    ....
  7. ncbi Neuregulin-1 regulates cell adhesion via an ErbB2/phosphoinositide-3 kinase/Akt-dependent pathway: potential implications for schizophrenia and cancer
    Christopher G Kanakry
    Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 2:e1369. 2007
    ....
  8. ncbi The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin
    Alice P Liou
    Digestive Diseases Branch, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Gastroenterology 140:903-12. 2011
    ..We sought to determine whether dietary fat-induced secretion of CCK is directly mediated by GPR40 expressed on I cells...
  9. ncbi DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
    Kenji Nakata
    Clinical Brain Disorders Branch, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Proc Natl Acad Sci U S A 106:15873-8. 2009
    ..Our results implicate a molecular mechanism of genetic risk associated with DISC1 involving specific alterations in gene processing...
  10. ncbi LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor
    E Koustova
    Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases/NIH, Bethesda, Maryland 20892-0008, USA
    J Clin Invest 107:737-44. 2001
    ..These Ab's may alter neuronal signaling and contribute to the neurodegeneration observed in these mice, actions that may be curtailed by the use of AMPA-receptor antagonists...
  11. ncbi Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization
    Yukihiko Iizuka
    Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland 20892 1385, USA
    J Neurosci 27:12390-5. 2007
    ..Such an increase in DRD2 signaling relative to DRD1 would contribute to the imbalances in dopaminergic neurotransmission characteristic of schizophrenia...
  12. ncbi Central nervous system infection in a murine retrovirus-induced immunodeficiency syndrome
    Y Sei
    Laboratory of Neuroscience, NIDDK, National Institutes of Health, Bethesda, MD 20892
    J Neuroimmunol 37:131-40. 1992
    ....
  13. ncbi Multiple effects of caffeine on Ca2+ release and influx in human B lymphocytes
    Y Sei
    Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 4799, USA
    Cell Calcium 29:149-60. 2001
    ..Our results suggest the need for caution regarding use of caffeine simply as a RYR-activator to study Ca2+ homeostasis in eucaryotic cells...
  14. ncbi Extracellular glutamate levels are chronically elevated in the brains of LP-BM5-infected mice: a mechanism of retrovirus-induced encephalopathy
    M G Espey
    Laboratory of Neuroscience, National Institute of Digestive Disorders and Kidney, National Institutes of Health, Bethesda, Maryland 20892 0008, USA
    J Neurochem 71:2079-87. 1998
    ....
  15. ncbi The encephalopathy associated with murine acquired immunodeficiency syndrome
    Y Sei
    Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 840:822-34. 1998
    ....
  16. ncbi Altered brain fyn kinase in a murine acquired immunodeficiency syndrome
    Y Sei
    Laboratory of Neuroscience, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    FASEB J 10:339-44. 1996
    ..These findings suggest that virus-associated disruption of fyn kinase-mediated signaling contributes to the cognitive deficits observed in mice with MAIDS and other retrovirus-induced encephalopathies...
  17. ncbi Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes
    Yoshitatsu Sei
    Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
    Anesthesiology 97:1052-8. 2002
    ..Because human B lymphocytes express the RYR1, it is hypothesized that Ca2+ homeostasis in B lymphocytes is altered in MHS individuals...
  18. ncbi The influence of a targeted deletion of the IFNgamma gene on emotional behaviors
    Y Kustova
    Laboratory of Bio organic Chemistry, NIDDK, Bethesda, MD 20892, USA
    Brain Behav Immun 12:308-24. 1998
    ....
  19. ncbi Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes
    Y Sei
    Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
    J Biol Chem 274:5995-6002. 1999
    ....
  20. ncbi Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801
    A Linden
    A I Virtanen Institute, University of Kuopio, P O B 1627, 70211 Kuopio, Finland
    Neuropharmacology 40:469-81. 2001
    ..These results provide evidence for a contribution of Src and tyrosine phosphorylation of NMDA receptors in the pharmacological actions of uncompetitive NMDA receptor antagonists...