A Scuteri

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effect of estrogen and progestin replacement on arterial stiffness indices in postmenopausal women
    A Scuteri
    Gerontology Research Center, National Institute on Aging National Institutes of Health, Baltimore, Maryland 21224, USA
    Aging (Milano) 13:122-30. 2001
  2. ncbi request reprint Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness
    Angelo Scuteri
    Laboratory of Cardiovascular Science, Laboratory of Clinical Investigation, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224 6825, USA
    J Am Coll Cardiol 43:1388-95. 2004
  3. ncbi request reprint Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons. The Cardiovascular Health Study (CHS E-131)
    Angelo Scuteri
    Laboratory of Cardiovascular Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
    J Am Coll Cardiol 43:187-93. 2004
  4. pmc The burden of obesity on blood pressure is reduced in older persons: the SardiNIA study
    M I Pikilidou
    Laboratory of Cardiovascular Science, Gerontology Research Center, National Institute of Aging, Baltimore, Maryland, USA
    Obesity (Silver Spring) 21:E10-3. 2013
  5. ncbi request reprint Association of high resting end tidal CO2 with carotid artery thickness in women, but not men
    D E Anderson
    Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland 21224, USA
    J Hypertens 19:459-63. 2001
  6. ncbi request reprint Is the apoE4 allele an independent predictor of coronary events?
    A Scuteri
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
    Am J Med 110:28-32. 2001
  7. ncbi request reprint Functional correlates of central arterial geometric phenotypes
    A Scuteri
    Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    Hypertension 38:1471-5. 2001
  8. ncbi request reprint Anger inhibition potentiates the association of high end-tidal CO2 with blood pressure in women
    A Scuteri
    Laboratory of Cardiovascular Sciences, National Institute on Aging, Baltimore, Maryland 21224, USA
    Psychosom Med 63:470-5. 2001
  9. ncbi request reprint Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
    D A Kass
    Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circulation 104:1464-70. 2001
  10. ncbi request reprint Racial differences in resting end-tidal CO2 and circulating sodium pump inhibitor
    D E Anderson
    Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland 21224, USA
    Am J Hypertens 14:761-7. 2001

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Effect of estrogen and progestin replacement on arterial stiffness indices in postmenopausal women
    A Scuteri
    Gerontology Research Center, National Institute on Aging National Institutes of Health, Baltimore, Maryland 21224, USA
    Aging (Milano) 13:122-30. 2001
    ..In conclusion, ERT in postmenopausal women can beneficially affect the vascular system, by reducing BP and the age-associated increase in arterial stiffness. The addition of progestins to ERT may reduce these beneficial effects...
  2. ncbi request reprint Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness
    Angelo Scuteri
    Laboratory of Cardiovascular Science, Laboratory of Clinical Investigation, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224 6825, USA
    J Am Coll Cardiol 43:1388-95. 2004
    ..We sought to evaluate whether the clustering of multiple components of the metabolic syndrome (MS) has a greater impact on these vascular parameters than individual components of MS...
  3. ncbi request reprint Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons. The Cardiovascular Health Study (CHS E-131)
    Angelo Scuteri
    Laboratory of Cardiovascular Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
    J Am Coll Cardiol 43:187-93. 2004
    ..We hypothesized that variant geometric patterns of the common carotid artery (CCA) predict the incidence of cardiovascular disease (CVD), after accounting for CCA intima-medial thickness (IMT)...
  4. pmc The burden of obesity on blood pressure is reduced in older persons: the SardiNIA study
    M I Pikilidou
    Laboratory of Cardiovascular Science, Gerontology Research Center, National Institute of Aging, Baltimore, Maryland, USA
    Obesity (Silver Spring) 21:E10-3. 2013
    ..Being overweight or obese increases the risk of elevated blood pressure. However differences of their effects on blood pressure in different age groups are not clear...
  5. ncbi request reprint Association of high resting end tidal CO2 with carotid artery thickness in women, but not men
    D E Anderson
    Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland 21224, USA
    J Hypertens 19:459-63. 2001
    ..CONCLUSIONS: This study indicates that PetCO2 can play a role in cardiovascular structure, as well as function, in women, and that the relationship is independent of the association of PetCO2 with blood pressure...
  6. ncbi request reprint Is the apoE4 allele an independent predictor of coronary events?
    A Scuteri
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
    Am J Med 110:28-32. 2001
    ..Although the apolipoprotein E genotype epsilon4 (apoE4) has been associated with high cholesterol levels, whether it is an independent predictor of coronary events is not certain...
  7. ncbi request reprint Functional correlates of central arterial geometric phenotypes
    A Scuteri
    Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    Hypertension 38:1471-5. 2001
    ..The interplay among these factors, particularly circumferential wall and FSS, likely determines the CGP; conversely, the resultant CGP may modulate the FSS and wall stress for a given pressure and flow...
  8. ncbi request reprint Anger inhibition potentiates the association of high end-tidal CO2 with blood pressure in women
    A Scuteri
    Laboratory of Cardiovascular Sciences, National Institute on Aging, Baltimore, Maryland 21224, USA
    Psychosom Med 63:470-5. 2001
    ..Additional studies are needed to determine the origins of the observed gender differences and the psychophysiological pathways by which high resting PetCO2 contributes to elevated resting blood pressure in women...
  9. ncbi request reprint Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
    D A Kass
    Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circulation 104:1464-70. 2001
    ..We tested whether ALT-711, a novel nonenzymatic breaker of advanced glycation end-product crosslinks, selectively improves arterial compliance and lowers pulse pressure in older individuals with vascular stiffening...
  10. ncbi request reprint Racial differences in resting end-tidal CO2 and circulating sodium pump inhibitor
    D E Anderson
    Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland 21224, USA
    Am J Hypertens 14:761-7. 2001
    ....
  11. ncbi request reprint Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women
    Angelo Scuteri
    Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, Maryland, USA
    J Hypertens 21:1339-46. 2003
    ..We determined whether changes in endothelium-dependent vasodilation (EDD) and plasma ADMA predict changes in blood pressure (BP) after salt loading in normotensive postmenopausal women (PMW)...
  12. ncbi request reprint Aortic correlates of clinical markers of large artery structure and function. Effects of aging and hypertension
    Angelo Scuteri
    UO Geriatria, INRCA IRCCS, Via Cassia 1167, 00189 Roma, Italy
    Aging Clin Exp Res 18:452-61. 2006
    ..However, neither their relations with aorta properties nor the effects of aging and hypertension on those relations are yet clear...
  13. ncbi request reprint Slowing arterial aging: how far have we progressed?
    Angelo Scuteri
    J Hypertens 25:509-10. 2007
  14. ncbi request reprint Carotid intima-media thickness, carotid distensibility and mitral, aortic valve calcification: a useful diagnostic parameter of systemic atherosclerotic disease
    Luca Sgorbini
    Unit of Cardiology, INRCA IRCCS Hospital, Rome, Italy
    J Cardiovasc Med (Hagerstown) 8:342-7. 2007
    ..Common carotid intima-media thickness (cIMT) and distensibility (cDIST) are also independent predictors of adverse cardiovascular outcomes. We examined the relationship between the degree of MAC-AVC and cIMT and cDIST...
  15. ncbi request reprint Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome
    Angelo Scuteri
    UO Geriatria, INRCA IRCCS, Via Cassia 1167, 00189 Rome, Italy
    Nutr Metab Cardiovasc Dis 18:349-56. 2008
    ....
  16. ncbi request reprint Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging
    Shari R Waldstein
    Department of Psychology, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA
    Hypertension 51:99-104. 2008
    ..Aggressive treatment of risk factors associated with greater arterial stiffness may help preserve cognitive function with individuals' increasing age...
  17. ncbi request reprint Pulse pressure is inversely related to aortic root diameter implications for the pathogenesis of systolic hypertension
    S Morteza Farasat
    Laboratory of Cardiovascular Science, Clinical Research Branch, National Institute on Aging, National Institutes of Health, 3001 South Hanover St, Baltimore, MD 21225, USA
    Hypertension 51:196-202. 2008
    ..40; P=0.01; model R(2)=0.61). Thus, AoD is inversely associated with PP, suggesting that a small AoD may contribute to the pathogenesis of systolic hypertension. Longitudinal studies are needed to examine this possibility...
  18. pmc Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging
    Samer S Najjar
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Coll Cardiol 51:1377-83. 2008
    ..This study sought to evaluate whether pulse wave velocity (PWV), a noninvasive index of arterial stiffness, is a predictor of the longitudinal changes in systolic blood pressure (SBP) and of incident hypertension...
  19. doi request reprint Do hypertensive individuals have enlarged aortic root diameters? Insights from studying the various subtypes of hypertension
    S Morteza Farasat
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Hypertens 21:558-63. 2008
    ..We assessed whether AoD differs among subjects with the various subtypes of hypertension and nonhypertensive individuals...
  20. pmc Heritability of cardiovascular and personality traits in 6,148 Sardinians
    Giuseppe Pilia
    Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Ospedale Microcitemico, Cagliari, Italy
    PLoS Genet 2:e132. 2006
    ..Evidence for heterogeneity by age and sex suggests that models allowing for these differences will be important in mapping quantitative traits...
  21. ncbi request reprint Age-related changes in cognitive domains. A population-based study
    Angelo Scuteri
    Centro Nazionale di Epidemiologia, Sorveglianza e Promozione della Salute, Istituto Superiore di Sanita, Roma, Italy
    Aging Clin Exp Res 17:367-73. 2005
    ....
  22. ncbi request reprint apoE4 allele and the natural history of cardiovascular risk factors
    Angelo Scuteri
    Laboratory of Cardiovascular Science, NIA NIH, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
    Am J Physiol Endocrinol Metab 289:E322-7. 2005
    ..In conclusion, apoE4 influences fasting plasma glucose and its changes over time. This could explain, in part, the increased CV risk associated with the apoE4 genotype observed in men...
  23. ncbi request reprint The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the Cardiovascular Health Study
    Angelo Scuteri
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
    Diabetes Care 28:882-7. 2005
    ..We also compared the prognostic significance of the two definitions of the metabolic syndrome...
  24. ncbi request reprint Blood pressure, arterial function, structure, and aging: the role of hormonal replacement therapy in postmenopausal women
    Angelo Scuteri
    Unita Operativa di Geriatria, INRCA, Rome, Italy
    J Clin Hypertens (Greenwich) 5:219-25. 2003
    ....
  25. ncbi request reprint Effect of light-to-moderate alcohol consumption on age-associated arterial stiffening
    Hidetaka Hougaku
    Clinical Research Branch, Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    Am J Cardiol 95:1006-10. 2005
    ..A U-shaped relation was found between alcohol intake and a stiffness index, with the lowest index in moderate drinkers, which may partially explain the relation between alcohol and cardiovascular disease...
  26. ncbi request reprint Arterial stiffness is an independent risk factor for cognitive impairment in the elderly: a pilot study
    Angelo Scuteri
    UO Geriatria, INRCA IRCCS, Roma, Italy
    J Hypertens 23:1211-6. 2005
    ....
  27. ncbi request reprint Ethnic variation in hypertension among premenopausal and perimenopausal women: Study of Women's Health Across the Nation
    Donald M Lloyd-Jones
    Division of Cardiology, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Hypertension 46:689-95. 2005
    ..Treatment and control rates vary considerably across ethnicities. Greater efforts must be made to improve hypertension awareness, treatment, and control in all middle-aged women, particularly those in ethnic minority groups...
  28. pmc Association of mitral annulus calcification, aortic valve calcification with carotid intima media thickness
    Luca Sgorbini
    Cardiologic Unit I N R C A I R C C S, Roma, Italy
    Cardiovasc Ultrasound 2:19. 2004
    ..Alterations in vascular structure, as indexed by the intima media thickness (IMT), are also recognized as independent predictors of adverse cardiovascular outcomes...
  29. pmc Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
    Wei Min Chen
    Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA
    J Clin Invest 118:2620-8. 2008
    ....
  30. ncbi request reprint Transdermal 17 beta-oestradiol reduces salt sensitivity of blood pressure in postmenopausal women
    Angelo Scuteri
    J Hypertens 21:2419-20. 2003
  31. doi request reprint Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    Cristen J Willer
    Center for Statistical Genetics, Department of Biostatistics, University of Michigan, 1420 Washington Heights, Ann Arbor, Michigan 48109, USA
    Nat Genet 40:161-9. 2008
    ..Notably, the 11 independent variants associated with increased LDL cholesterol concentrations in our study also showed increased frequency in a sample of coronary artery disease cases versus controls...
  32. pmc The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts
    Siguang Li
    Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, United States of America
    PLoS Genet 3:e194. 2007
    ..Our results suggest that polymorphisms in GLUT9 could affect glucose metabolism and uric acid synthesis and/or renal reabsorption, influencing serum uric acid levels over a wide range of values...
  33. pmc Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    Angelo Scuteri
    Unità Operativa Geriatria, Istituto per la Patologia Endocrina e Metabolica, Rome, Italy
    PLoS Genet 3:e115. 2007
    ..These changes could have a significant impact on the risk of obesity-related morbidity in the general population...
  34. ncbi request reprint Arterial stiffness as an independent predictor of longitudinal changes in cognitive function in the older individual
    Angelo Scuteri
    UO Geriatria, INRCA IRCCS, Rome, Italy
    J Hypertens 25:1035-40. 2007
    ..The present study aimed to evaluate PWV as a predictor of longitudinal changes in cognitive function in older individuals reporting memory problems...
  35. ncbi request reprint Arterial aging: is it an immutable cardiovascular risk factor?
    Samer S Najjar
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
    Hypertension 46:454-62. 2005
    ..It is our hope that a greater appreciation of the links between arterial aging and cardiovascular diseases will stimulate further investigation into strategies aimed at preventing or retarding arterial aging...