Research Topics
Genomes and GenesSpecies | Thomas G SchulzeSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorderT G Schulze
Unit on the Genetic Basis of Mood and Anxiety Disorders, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 3719, USA
Mol Psychiatry 14:487-91. 2009..Further analysis suggested that each marker contributed independently to BD, with no significant marker x marker interaction. Our findings strongly support ANK3 as a BD susceptibility gene and suggest true allelic heterogeneity...
Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterizationThomas G Schulze
Unit on the Genetic Basis of Mood and Anxiety Disorders, National Institute of Mental Health NIMH, National Institutes of Health NIH, Bethesda, MD 20892 3719, USA
Psychiatr Clin North Am 33:67-82. 2010..It furthermore sketches out a potential research framework integrating various lines of research into the molecular biological basis of BD...
The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatmentThomas G Schulze
Genetic Basis of Mood and Anxiety Disorders, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 3719, USA
Neuropsychobiology 62:72-8. 2010..A stringent phenotype definition of response is one of the hallmarks of this collaboration. ConLiGen invites all lithium researchers to join its efforts...
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1Francis J McMahon
Unit on the Genetic Basis of Mood and Anxiety Disorders, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Nat Genet 42:128-31. 2010..83-0.92), with supportive evidence for association observed in two out of three independent replication cohorts. These results provide an example of a shared genetic susceptibility locus for bipolar disorder and MDD...
The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populationsJohannes Schumacher
Unit on the Genetic Basis of Mood and Anxiety Disorders, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 3719, USA
Hum Mol Genet 18:2719-27. 2009..Furthermore, our phenotype-genotype results--including the consideration of sex-specific effects--highlight the value of homogenous samples in mapping risk genes for schizophrenia in general, and at the DISC locus in particular...
The European Federation of Psychiatric Trainees (EFPT)--an integral part of the European harmonisation of psychiatric education and practiseThomas G Schulze
National Institute of Mental Health, Mood and Anxiety Disorders Program, National Institutes of Health, Bethesda, MD 20892, USA
Eur Psychiatry 17:300-5. 2002....
Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorderD T Chen
Human Genetics Branch, National Institute of Mental Health, Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
Mol Psychiatry 18:195-205. 2013..Further studies are needed to replicate these findings and may potentially lead to identification of functional variants. Sample size will remain a limiting factor in the discovery of common alleles associated with BD...
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigreesThomas G Schulze
Genetic Basis of Mood and Anxiety Disorders, Mood and Anxiety Program, Bethesda, USA
Biol Psychiatry 56:18-23. 2004....
