S W Scholz

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations
    Sonja W Scholz
    Molecular Genetics Unit, National Institute on Aging, National Institutes of Health, Building 35, Room 1A 1012, Bethesda, MD 20892, USA
    Neurosci Lett 395:227-9. 2006
  2. doi request reprint Parkin and PINK1 mutations in early-onset Parkinson's disease: comprehensive screening in publicly available cases and control
    J Brooks
    Laboratory of Neurogenetics, National Institute on Aging, 35 Convent Drive, 20892 Bethesda, USA
    J Med Genet 46:375-81. 2009
  3. pmc SNCA variants are associated with increased risk for multiple system atrophy
    Sonja W Scholz
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA
    Ann Neurol 65:610-4. 2009
  4. pmc Genome-wide association study reveals genetic risk underlying Parkinson's disease
    Javier Simon-Sanchez
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 41:1308-12. 2009
  5. ncbi request reprint Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data
    Jennifer C Schymick
    Laboratory of Neurogenetics, National Institute on Aging, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Lancet Neurol 6:322-8. 2007
  6. doi request reprint Genotype, haplotype and copy-number variation in worldwide human populations
    Mattias Jakobsson
    Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 451:998-1003. 2008

Collaborators

Detail Information

Publications6

  1. ncbi request reprint The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations
    Sonja W Scholz
    Molecular Genetics Unit, National Institute on Aging, National Institutes of Health, Building 35, Room 1A 1012, Bethesda, MD 20892, USA
    Neurosci Lett 395:227-9. 2006
    ..No association between genotypes in codon 129 and IPD was detected in three distinct populations, suggesting that this PRNP polymorphism has no direct influence on the susceptibility to IPD...
  2. doi request reprint Parkin and PINK1 mutations in early-onset Parkinson's disease: comprehensive screening in publicly available cases and control
    J Brooks
    Laboratory of Neurogenetics, National Institute on Aging, 35 Convent Drive, 20892 Bethesda, USA
    J Med Genet 46:375-81. 2009
    ..The possibility that heterozygous mutations in these genes also predispose to disease or lower the age of disease onset has been suggested, but currently there is insufficient data to verify this hypothesis conclusively...
  3. pmc SNCA variants are associated with increased risk for multiple system atrophy
    Sonja W Scholz
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA
    Ann Neurol 65:610-4. 2009
    ..SNPs at the SNCA locus were significantly associated with risk for increased risk for the development of MSA (combined p = 5.5 x 10(-12); odds ratio 6.2) [corrected]...
  4. pmc Genome-wide association study reveals genetic risk underlying Parkinson's disease
    Javier Simon-Sanchez
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 41:1308-12. 2009
    ..14, P = 1.55 x 10(-5)). These data demonstrate an unequivocal role for common genetic variants in the etiology of typical PD and suggest population-specific genetic heterogeneity in this disease...
  5. ncbi request reprint Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data
    Jennifer C Schymick
    Laboratory of Neurogenetics, National Institute on Aging, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Lancet Neurol 6:322-8. 2007
    ..We sought to identify genetic variants associated with an increased or decreased risk for developing ALS in a cohort of American sporadic cases...
  6. doi request reprint Genotype, haplotype and copy-number variation in worldwide human populations
    Mattias Jakobsson
    Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 451:998-1003. 2008
    ..Our results produce new inferences about inter-population variation, support the utility of CNVs in human population-genetic research, and serve as a genomic resource for human-genetic studies in diverse worldwide populations...