Peter J Schmidt

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Cognitive performance in healthy women during induced hypogonadism and ovarian steroid addback
    Peter J Schmidt
    Section on Behavioral Endocrinology, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1277, USA
    Arch Womens Ment Health 16:47-58. 2013
  2. pmc Pharmacologically induced hypogonadism and sexual function in healthy young women and men
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1276, USA
    Neuropsychopharmacology 34:565-76. 2009
  3. pmc Sex hormones and mood in the perimenopause
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1179:70-85. 2009
  4. pmc Depression in women with spontaneous 46, XX primary ovarian insufficiency
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, 10 Center Drive MSC 1277, Bethesda, Maryland 20892 1277, USA
    J Clin Endocrinol Metab 96:E278-87. 2011
  5. ncbi request reprint Reproductive ageing, sex steroids and depression
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1276, USA
    J Br Menopause Soc 12:178-85. 2006
  6. ncbi request reprint Mood, depression, and reproductive hormones in the menopausal transition
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892 1276, USA
    Am J Med 118:54-8. 2005
  7. ncbi request reprint Depression, the perimenopause, and estrogen therapy
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bldg 10 CRC, Rm 6 5340, 10 Center Dr, MSC 1276, Bethesda, MD 20892 1276, USA
    Ann N Y Acad Sci 1052:27-40. 2005
  8. ncbi request reprint Dehydroepiandrosterone monotherapy in midlife-onset major and minor depression
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Rockville, MD 20892 1276, USA
    Arch Gen Psychiatry 62:154-62. 2005
  9. ncbi request reprint A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women
    Peter J Schmidt
    Behavioral Endocrinology Branch, NIMH, NIH, Department of Health and Human Services, Rm 3N238, Bldg 10, 10 Center Dr, MSC 1276, Bethesda, MD 20892 1276, USA
    Am J Psychiatry 161:2238-44. 2004
  10. ncbi request reprint The effects of pharmacologically induced hypogonadism on mood in healthy men
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1276, USA
    Arch Gen Psychiatry 61:997-1004. 2004

Collaborators

Detail Information

Publications38

  1. pmc Cognitive performance in healthy women during induced hypogonadism and ovarian steroid addback
    Peter J Schmidt
    Section on Behavioral Endocrinology, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1277, USA
    Arch Womens Ment Health 16:47-58. 2013
    ..Differences in the clinical characteristics of the women receiving GnRH agonists could predict a risk for ovarian steroid-related changes in cognitive performance during induced, and possibly, natural menopause...
  2. pmc Pharmacologically induced hypogonadism and sexual function in healthy young women and men
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1276, USA
    Neuropsychopharmacology 34:565-76. 2009
    ....
  3. pmc Sex hormones and mood in the perimenopause
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1179:70-85. 2009
    ..Thus, although depression is not a uniform accompaniment of the menopause transition, in some women, age-related changes in ovarian estrogen production may alter central nervous system function and predispose them to develop depression...
  4. pmc Depression in women with spontaneous 46, XX primary ovarian insufficiency
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, 10 Center Drive MSC 1277, Bethesda, Maryland 20892 1277, USA
    J Clin Endocrinol Metab 96:E278-87. 2011
    ..Indeed, studies suggest that depression and/or its pharmacological treatment contribute to the onset of POI...
  5. ncbi request reprint Reproductive ageing, sex steroids and depression
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1276, USA
    J Br Menopause Soc 12:178-85. 2006
    ..Future studies of perimenopausal depression should identify the number of women affected, individual risk factors and the role of hormonal therapies in this condition...
  6. ncbi request reprint Mood, depression, and reproductive hormones in the menopausal transition
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892 1276, USA
    Am J Med 118:54-8. 2005
    ....
  7. ncbi request reprint Depression, the perimenopause, and estrogen therapy
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bldg 10 CRC, Rm 6 5340, 10 Center Dr, MSC 1276, Bethesda, MD 20892 1276, USA
    Ann N Y Acad Sci 1052:27-40. 2005
    ..Thus, although depression is not a uniform accompaniment of the menopausal transition, in some women age-related changes in ovarian estrogen production may alter central nervous system function and predispose them to develop depression...
  8. ncbi request reprint Dehydroepiandrosterone monotherapy in midlife-onset major and minor depression
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Rockville, MD 20892 1276, USA
    Arch Gen Psychiatry 62:154-62. 2005
    ..The adrenal androgen and neurosteroid dehydroepiandrosterone (DHEA) is available as over-the-counter hormonal therapy and previously has been reported to have antidepressant-like effects...
  9. ncbi request reprint A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women
    Peter J Schmidt
    Behavioral Endocrinology Branch, NIMH, NIH, Department of Health and Human Services, Rm 3N238, Bldg 10, 10 Center Dr, MSC 1276, Bethesda, MD 20892 1276, USA
    Am J Psychiatry 161:2238-44. 2004
    ..Mood and reproductive function were prospectively evaluated in asymptomatic premenopausal women to determine whether the onset of depression was temporally linked to the perimenopause...
  10. ncbi request reprint The effects of pharmacologically induced hypogonadism on mood in healthy men
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1276, USA
    Arch Gen Psychiatry 61:997-1004. 2004
    ..The effects of declining androgen secretion on mood regulation and the potential psychotropic efficacy of androgen replacement in men are largely undetermined...
  11. ncbi request reprint Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men
    Miki Bloch
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Arch Gen Psychiatry 63:450-6. 2006
    ..Although the behavioral effects of high-dose androgen administration may involve alterations in serotonergic activity, few studies have investigated the impact of androgen withdrawal on the central nervous system in humans...
  12. ncbi request reprint Abnormal luteal phase excitability of the motor cortex in women with premenstrual syndrome
    Mark J Smith
    National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland 20892, USA
    Biol Psychiatry 54:757-62. 2003
    ..Here, we studied women with PMS to see if their response to endogenous progesterone differed from that of control subjects...
  13. doi request reprint Effects of pharmacologically induced hypogonadism on mood and behavior in healthy young women
    Rivka Ben Dor
    Section on Behavioral Endocrinology, NIMH, Department of Health and Human Services, Bethesda, MD, USA
    Am J Psychiatry 170:426-33. 2013
    ....
  14. pmc Rapid response to fluoxetine in women with premenstrual dysphoric disorder
    Emma M Steinberg
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Depress Anxiety 29:531-40. 2012
    ..Selective serotonin reuptake inhibitors (SRIs) relieve irritability within days in women with premenstrual dysphoric disorder (PMDD); however, the effects on other affective symptoms in PMDD remain to be demonstrated...
  15. ncbi request reprint Sex-related differences in stimulated hypothalamic-pituitary-adrenal axis during induced gonadal suppression
    Catherine A Roca
    Office of Special Populations, National Institute of Mental Health, Rockville, Maryland 20857, USA
    J Clin Endocrinol Metab 90:4224-31. 2005
    ..Sex-related differences in reproductive steroid levels further confound efforts to define the specific role of the sex of the individual in stress axis responsivity...
  16. pmc Facial emotion discrimination across the menstrual cycle in women with premenstrual dysphoric disorder (PMDD) and controls
    David R Rubinow
    Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda MD 20892 1276, United States
    J Affect Disord 104:37-44. 2007
    ..e., state dependent)...
  17. ncbi request reprint Concordant restoration of ovarian function and mood in perimenopausal depression
    Robert C Daly
    Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892 1276, USA
    Am J Psychiatry 160:1842-6. 2003
    ..The purpose of this study was to examine changes in mood and pituitary-ovarian axis function in women exhibiting perimenopausal depression...
  18. ncbi request reprint Premenstrual symptoms and perimenopausal depression
    Misty Richards
    Behavioral Endocrinology Branch, NIMH, NIH, U S Department of Health and Human Services, Bethesda, MD, USA
    Am J Psychiatry 163:133-7. 2006
    ..Premenstrual mood symptoms were evaluated in women with perimenopause-related depression...
  19. pmc A cross-sectional evaluation of perimenopausal depression
    Emma M Steinberg
    Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892 1276, USA
    J Clin Psychiatry 69:973-80. 2008
    ....
  20. pmc Testosterone suppression of CRH-stimulated cortisol in men
    David R Rubinow
    Behavioral Endocrinology Branch, National Institute of Mental Health, Building 10 CRC, 10 Center Drive MSC 1276, Bethesda, MD 20892 1276, USA
    Neuropsychopharmacology 30:1906-12. 2005
    ..Our results further demonstrate that the enhanced stimulated HPA axis activity previously described in young men compared with young women cannot be ascribed to an activational upregulation of the axis by testosterone...
  21. pmc Reproductive aging, sex steroids, and mood disorders
    Veronica Harsh
    Section on Behavioral Endocrinology, National Institute of Mental Health, Bethesda, MD 20892 1276, USA
    Harv Rev Psychiatry 17:87-102. 2009
    ..Finally, we discuss possible causes of affective disturbances during the menopause transition...
  22. ncbi request reprint The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892 1276, USA
    Neuropsychopharmacology 27:800-12. 2002
    ....
  23. pmc ACTH and cortisol response to Dex/CRH testing in women with and without premenstrual dysphoria during GnRH agonist-induced hypogonadism and ovarian steroid replacement
    Ellen E Lee
    Section on Behavioral Endocrinology, National Institute of Mental Health, Bethesda, Maryland 20892 1277, USA
    J Clin Endocrinol Metab 97:1887-96. 2012
    ....
  24. ncbi request reprint Effects of metergoline on symptoms in women with premenstrual dysphoric disorder
    Catherine A Roca
    National Institute of Mental Health, Bethesda, MD 20892 1277, USA
    Am J Psychiatry 159:1876-81. 2002
    ..The authors investigated the role of acute serotonergic modulation in the efficacy of selective serotonin reuptake inhibitors (SSRIs) in women with premenstrual dysphoric disorder...
  25. ncbi request reprint Operationalizing DSM-IV criteria for PMDD: selecting symptomatic and asymptomatic cycles for research
    Mark J Smith
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bldg 10, Room 3N238, 10 Center Dr MSC 1276, Bethesda MD 20892 1276, USA
    J Psychiatr Res 37:75-83. 2003
    ..At the very least, the method for operationalizing DSM-IV criteria should be described in studies of PMDD...
  26. ncbi request reprint Differential menstrual cycle regulation of hypothalamic-pituitary-adrenal axis in women with premenstrual syndrome and controls
    Catherine A Roca
    Behavioral Endocrinology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 88:3057-63. 2003
    ..These data demonstrate that women with PMS, when symptomatic, appear to have an abnormal response to progesterone and, furthermore, do not display the HPA axis abnormalities characteristic of major depression...
  27. doi request reprint Abnormalities of dorsolateral prefrontal function in women with premenstrual dysphoric disorder: a multimodal neuroimaging study
    Erica B Baller
    Section on Integrative Neuroimaging, Clinical Brain Disorders Branch, Gene, Cognition, NIMH Intramural Research Programs, NIH, Bethesda, MD, USA
    Am J Psychiatry 170:305-14. 2013
    ....
  28. pmc Magnesium (mg) retention and mood effects after intravenous mg infusion in premenstrual dysphoric disorder
    Khursheed Khine
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1277, USA
    Biol Psychiatry 59:327-33. 2006
    ..Conflicting data exist regarding the presence of magnesium (Mg) deficiency and the therapeutic efficacy of Mg in premenstrual syndrome or premenstrual dysphoric disorder (PMDD)...
  29. ncbi request reprint Gonadal steroid regulation of mood: the lessons of premenstrual syndrome
    David R Rubinow
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1276, USA
    Front Neuroendocrinol 27:210-6. 2006
    ....
  30. ncbi request reprint Effects of ovarian hormones on human cortical excitability
    Mark J Smith
    Brain Stimulation Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1430, USA
    Ann Neurol 51:599-603. 2002
    ..These findings demonstrate an excitatory neuronal effect associated with estradiol and confirm our earlier finding of inhibition associated with progesterone...
  31. ncbi request reprint The menopause transition: the next neuroendocrine frontier
    Veronica Harsh
    National Institutes of Health, Behavioral Endocrinology Branch, National Institute of Mental Health, Department of Health and Human Services, Bldg 10 CRC, Room 65340, 10 Center Drive MSC 1276, Bethesda, MD 20892 1276, USA
    Expert Rev Neurother 7:S7-10. 2007
  32. pmc Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene
    Liang Huo
    Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 62:925-33. 2007
    ..Premenstrual dysphoric disorder (PMDD) is a heritable mood disorder that is triggered by gonadal steroids during the luteal phase in susceptible women...
  33. pmc Menstrual cycle phase modulates reward-related neural function in women
    Jean Claude Dreher
    Section on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:2465-70. 2007
    ....
  34. ncbi request reprint Why study reproductive neuroscience? A clinical perspective
    Peter J Schmidt
    Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    J Clin Psychiatry 69:972. 2008
  35. ncbi request reprint Differentiation of women with premenstrual dysphoric disorder, recurrent brief depression, and healthy controls by daily mood rating dynamics
    Steven M Pincus
    J Psychiatr Res 42:337-47. 2008
    ..The statistical methodologies have broad and direct applicability to behavioral studies for many psychiatric disorders, and indeed to similar analyses of associated biological signals across multiple axes...
  36. ncbi request reprint Cortisol response to ovine corticotropin-releasing hormone in a model of pregnancy and parturition in euthymic women with and without a history of postpartum depression
    Miki Bloch
    Department of Psychiatry, Tel Aviv Sourasky Medical Center, Israel 64239
    J Clin Endocrinol Metab 90:695-9. 2005
    ....
  37. pmc Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society
    Wulf H Utian
    Menopause 15:584-602. 2008
    ....
  38. ncbi request reprint Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women
    John H Morrison
    Fishberg Department of Neuroscience, Kastor Neurobiology of Aging Laboratories, New York, New York 10029, USA
    J Neurosci 26:10332-48. 2006