Marco L Schito

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis
    Marco Schito
    Division of AIDS, Henry M Jackson Foundation for Advancement of Military Medicine, National Institutes of Health, Bethesda, Maryland 20892 7628, USA
    J Infect Dis 205:S169-80. 2012
  2. ncbi Challenges for rapid molecular HIV diagnostics
    Marco L Schito
    Henry Jackson Foundation for the Advancement of Military Medicine, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20817, USA
    J Infect Dis 201:S1-6. 2010
  3. ncbi In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model
    Marco L Schito
    Chemical Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 19:91-101. 2003
  4. ncbi Cutting edge: in vivo induction of integrated HIV-1 expression by mycobacteria is critically dependent on Toll-like receptor 2
    Andre Bafica
    Immunobiology Section, National Institute of Allergy and Infectious Diseases and Chemical Immunology Section, Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 171:1123-7. 2003
  5. ncbi Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation
    Marco L Schito
    Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 176:4818-25. 2006
  6. ncbi Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys
    Marco L Schito
    Laboratory of Cell Biology, National Cancer Institute, National Institute of Health, Bethesda, Maryland 20892, USA
    Curr HIV Res 4:379-86. 2006
  7. ncbi Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer
    Lisa M Miller Jenkins
    Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Chem Biol 6:887-9. 2010
  8. ncbi Topical microbicides: a promising approach for controlling the AIDS pandemic via retroviral zinc finger inhibitors
    Jim A Turpin
    Preventions Sciences Program, Division of AIDS, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    Adv Pharmacol 56:229-56. 2008

Detail Information

Publications8

  1. ncbi Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis
    Marco Schito
    Division of AIDS, Henry M Jackson Foundation for Advancement of Military Medicine, National Institutes of Health, Bethesda, Maryland 20892 7628, USA
    J Infect Dis 205:S169-80. 2012
    ..In this fashion, the global community can best harness the tremendous capacity of novel diagnostics in fighting these 2 scourges...
  2. ncbi Challenges for rapid molecular HIV diagnostics
    Marco L Schito
    Henry Jackson Foundation for the Advancement of Military Medicine, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20817, USA
    J Infect Dis 201:S1-6. 2010
    ..The way forward requires sound scientific judgment and an ability to further develop and implement these tests despite a variety of technical, social, and operational hurdles, to declare success...
  3. ncbi In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model
    Marco L Schito
    Chemical Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 19:91-101. 2003
    ..Thus, these thioesters may provide an effective means for inhibiting the expression of human immunodeficiency virus from integrated viral reservoirs...
  4. ncbi Cutting edge: in vivo induction of integrated HIV-1 expression by mycobacteria is critically dependent on Toll-like receptor 2
    Andre Bafica
    Immunobiology Section, National Institute of Allergy and Infectious Diseases and Chemical Immunology Section, Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 171:1123-7. 2003
    ..Together, these results argue that TLR2 plays a crucial role in the activation of HIV-1 expression by mycobacterial coinfections...
  5. ncbi Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation
    Marco L Schito
    Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 176:4818-25. 2006
    ..In contrast, the abnormal thymic phenotype of Wip1-deficient mice was reversed in the absence of p53. These data suggest that Wip1 down-regulates p53 activation in the thymus and is required for normal alphabeta T cell development...
  6. ncbi Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys
    Marco L Schito
    Laboratory of Cell Biology, National Cancer Institute, National Institute of Health, Bethesda, Maryland 20892, USA
    Curr HIV Res 4:379-86. 2006
    ..Further studies directed at optimizing SAMT bioavailability and pharmacokinetics likely will result in enhanced therapeutic efficacy of this promising HIV therapeutic...
  7. ncbi Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer
    Lisa M Miller Jenkins
    Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Chem Biol 6:887-9. 2010
    ..The thiol produced by SAMT reaction with NCp7 is acetylated by cellular enzymes to regenerate active SAMTs via a recycling mechanism unique among small-molecule inhibitors of HIV...
  8. ncbi Topical microbicides: a promising approach for controlling the AIDS pandemic via retroviral zinc finger inhibitors
    Jim A Turpin
    Preventions Sciences Program, Division of AIDS, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    Adv Pharmacol 56:229-56. 2008