A Schatzkin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokers
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    Am J Epidemiol 169:542-53. 2009
  2. pmc Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysis
    C C Abnet
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Br J Cancer 100:551-7. 2009
  3. pmc Effect of smoking status on total energy expenditure
    David P Bradley
    Department of Nutritional Sciences, University of Wisconsin, Madison, WI, USA
    Nutr Metab (Lond) 7:81. 2010
  4. pmc Can we use biomarkers in combination with self-reports to strengthen the analysis of nutritional epidemiologic studies?
    Laurence S Freedman
    Biostatistics Unit, Gertner Institute for Epidemiology, Tel Hashomer 52161, Israel
    Epidemiol Perspect Innov 7:2. 2010
  5. pmc Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Breast Cancer Res 10:R38. 2008
  6. pmc Prospective study of physical activity and risk of postmenopausal breast cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Breast Cancer Res 10:R92. 2008
  7. pmc A prospective study of physical activity and the risk of pancreatic cancer among women (United States)
    Brook A Calton
    Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
    BMC Cancer 8:63. 2008
  8. pmc Prospective study of dietary fiber, whole grain foods, and small intestinal cancer
    Arthur Schatzkin
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
    Gastroenterology 135:1163-7. 2008
  9. ncbi request reprint A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study
    Arthur Schatzkin
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Epidemiol 32:1054-62. 2003
  10. pmc Mendelian randomization: how it can--and cannot--help confirm causal relations between nutrition and cancer
    Arthur Schatzkin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    Cancer Prev Res (Phila) 2:104-13. 2009

Collaborators

Detail Information

Publications124 found, 100 shown here

  1. pmc Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokers
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    Am J Epidemiol 169:542-53. 2009
    ..The inverse findings among former and current smokers in combination with the null results for physical activity among never smokers may point toward residual confounding by cigarette smoking as an explanation for the relations observed...
  2. pmc Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysis
    C C Abnet
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Br J Cancer 100:551-7. 2009
    ..64 (0.52-0.80), 0.82 (0.65-1.04), and 0.64 (0.52-0.79), respectively. The corresponding numbers for other NSAIDs were 0.68 (0.57-0.81), 0.80 (0.67-0.95), and 0.65 (0.50-0.85), respectively...
  3. pmc Effect of smoking status on total energy expenditure
    David P Bradley
    Department of Nutritional Sciences, University of Wisconsin, Madison, WI, USA
    Nutr Metab (Lond) 7:81. 2010
    ..Using doubly labeled water, we found no evidence of increased energy expenditure among smokers, however, it should be noted that BMI differences in this cohort also did not differ by smoking status...
  4. pmc Can we use biomarkers in combination with self-reports to strengthen the analysis of nutritional epidemiologic studies?
    Laurence S Freedman
    Biostatistics Unit, Gertner Institute for Epidemiology, Tel Hashomer 52161, Israel
    Epidemiol Perspect Innov 7:2. 2010
    ....
  5. pmc Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Breast Cancer Res 10:R38. 2008
    ..Epidemiologic evidence for a protective role of NSAIDs in breast cancer, however, is equivocal...
  6. pmc Prospective study of physical activity and risk of postmenopausal breast cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Breast Cancer Res 10:R92. 2008
    ..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
  7. pmc A prospective study of physical activity and the risk of pancreatic cancer among women (United States)
    Brook A Calton
    Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
    BMC Cancer 8:63. 2008
    ..Several epidemiologic studies have examined the association between physical activity and pancreatic cancer risk; however, the results of these studies are not consistent...
  8. pmc Prospective study of dietary fiber, whole grain foods, and small intestinal cancer
    Arthur Schatzkin
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
    Gastroenterology 135:1163-7. 2008
    ..We conducted a prospective cohort study to determine the relationship between intake of dietary fiber/whole grains and the incidence of small intestinal cancer...
  9. ncbi request reprint A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study
    Arthur Schatzkin
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Epidemiol 32:1054-62. 2003
    ..We use data from the Observing Protein and Energy Nutrition (OPEN) study to compare the performance of a FFQ with that of a 24-hour recall (24HR)...
  10. pmc Mendelian randomization: how it can--and cannot--help confirm causal relations between nutrition and cancer
    Arthur Schatzkin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    Cancer Prev Res (Phila) 2:104-13. 2009
    ..We conclude that Mendelian randomization is not universally applicable, but, under the right conditions, can complement evidence for causal associations from conventional epidemiologic studies...
  11. ncbi request reprint The promise and peril of surrogate end points in cancer research
    Arthur Schatzkin
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7232, USA
    Nat Rev Cancer 2:19-27. 2002
    ..Surrogate end points--markers of preclinical cancer or of imminent recurrence--are therefore an attractive alternative. But how can we be sure that a study with a surrogate outcome gives us the right answer about the true end point?..
  12. ncbi request reprint Design and serendipity in establishing a large cohort with wide dietary intake distributions : the National Institutes of Health-American Association of Retired Persons Diet and Health Study
    A Schatzkin
    National Cancer Institute, Bethesda, MD 20892 7232, USA
    Am J Epidemiol 154:1119-25. 2001
    ..The large size and wide intake range of the cohort will provide ample power for examining a number of important diet and cancer hypotheses...
  13. ncbi request reprint Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study
    Arthur Schatzkin
    Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Clin Nutr 85:1353-60. 2007
    ..Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent...
  14. ncbi request reprint Promises and perils of validating biomarkers for cancer risk
    Arthur Schatzkin
    Nutritional Epidemiology, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    J Nutr 136:2671S-2S. 2006
  15. ncbi request reprint Can biomarkers help us understand the nutritional and lifestyle factors important in cancer prognosis?
    Arthur Schatzkin
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20815, USA
    J Nutr 137:249S-252S. 2007
    ....
  16. ncbi request reprint Implementation of a 4-y, high-fiber, high-fruit-and-vegetable, low-fat dietary intervention: results of dietary changes in the Polyp Prevention Trial
    E Lanza
    National Cancer Institute, Bethesda, MD, USA
    Am J Clin Nutr 74:387-401. 2001
    ..30 g/MJ), high-fruit-and-vegetable (0.84 servings/MJ), low-fat (20% of energy from fat) diet on the recurrence of adenomatous polyps in the large bowel...
  17. pmc Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trial
    Gerd Bobe
    Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Prev Res (Phila) 3:764-75. 2010
    ..Our results suggest that serum IL-6 may serve as a risk indicator and as a response indicator to dietary flavonols for colorectal cancer prevention...
  18. pmc Alcohol and risk of breast cancer by histologic type and hormone receptor status in postmenopausal women: the NIH-AARP Diet and Health Study
    Jasmine Q Lew
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
    Am J Epidemiol 170:308-17. 2009
    ..13 (95% CI: 0.73, 1.77) for >20 g versus 0 g/day, and 1.21 (95% CI: 0.79, 1.84) for >20 g versus 0 g/day, respectively. Moderate consumption of alcohol was associated with breast cancer, specifically hormone receptor-positive tumors...
  19. ncbi request reprint Effects of dietary fat and fiber on plasma and urine androgens and estrogens in men: a controlled feeding study
    J F Dorgan
    Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, MD 20892 7326, USA
    Am J Clin Nutr 64:850-5. 1996
    ..01). Results of this study suggest that diet may alter endogenous sex hormone metabolism in men...
  20. ncbi request reprint Evaluation of 2 brief instruments and a food-frequency questionnaire to estimate daily number of servings of fruit and vegetables
    F E Thompson
    National Cancer Institute, Bethesda, MD, 20892 7344, USA
    Am J Clin Nutr 71:1503-10. 2000
    ..Measurement of fruit and vegetable intake is important in the surveillance of populations and in epidemiologic studies that examine the relations between diet and disease. Some situations require the use of brief dietary assessment tools...
  21. pmc The effect of strict adherence to a high-fiber, high-fruit and -vegetable, and low-fat eating pattern on adenoma recurrence
    Leah B Sansbury
    Division of Cancer Control and Population Sciences, 6130 Executive Boulevard, Room 5106, Mail Stop Code 7324, Bethesda, MD 20892, USA
    Am J Epidemiol 170:576-84. 2009
    ..65, 95% confidence interval: 0.47, 0.92). Findings suggest that high compliance with a low-fat, high-fiber diet is associated with reduced risk of adenoma recurrence...
  22. ncbi request reprint Evaluation of alternative approaches to assign nutrient values to food groups in food frequency questionnaires
    A F Subar
    National Cancer Institute, Bethesda, MD 20892 7344, USA
    Am J Epidemiol 152:279-86. 2000
    ..Mean methods for assigning nutrients to food groups were superior to median approaches for all measurements. Among the mean methods, no single variation was consistently better...
  23. ncbi request reprint Self-rated quality of life measures: effect of change to a low-fat, high-fiber, fruit and vegetable enriched diet
    D K Corle
    National Cancer Institute, Bethesda, MD 20892-7354, USA
    Ann Behav Med 23:198-207. 2001
    ..021), and health action (p < .001) domains significantly higher and the social domain significantly lower (p <.001) than control participants. These changes were consistent through Years 2, 3, and 4. This study..
  24. pmc Dietary fatty acids and pancreatic cancer in the NIH-AARP diet and health study
    Anne C M Thiebaut
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    J Natl Cancer Inst 101:1001-11. 2009
    ..Previous research relating dietary fat, a modifiable risk factor, to pancreatic cancer has been inconclusive...
  25. ncbi request reprint Hormone replacement therapy and colorectal adenoma recurrence among women in the Polyp Prevention Trial
    K Woodson
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute NIH, 6006 Executive Blvd, MSC 7058, Bethesda, MD 20892 7058, USA
    J Natl Cancer Inst 93:1799-805. 2001
    ....
  26. pmc Body mass index and risk of ovarian cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer 115:812-22. 2009
    ..However, to the authors' knowledge, data addressing whether the relation between BMI and ovarian cancer differs by MHT use are very sparse...
  27. pmc Body size and renal cell cancer incidence in a large US cohort study
    Kenneth F Adams
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Am J Epidemiol 168:268-77. 2008
    ..Waist-to hip ratio was positively associated with RCC in women and with height at age 18 years in both men and women...
  28. ncbi request reprint Fruit and vegetable intake and esophageal cancer in a large prospective cohort study
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 121:2753-60. 2007
    ..A significant inverse association between EAC and Chenopodiaceae (spinach) intake was observed. Results from our study suggest that the relation of fruit and vegetable intake and esophageal cancer risk may vary by histologic type...
  29. ncbi request reprint Physical activity and risk of ovarian cancer: a prospective cohort study in the United States
    Lindsay M Hannan
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS MSC 7232, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 13:765-70. 2004
    ..13). In this prospective cohort study among U.S. women, we found no overall significant association between physical activity and risk of ovarian cancer, although the results are suggestive of an inverse association...
  30. ncbi request reprint Lack of effect of a low-fat, high-fruit, -vegetable, and -fiber diet on serum prostate-specific antigen of men without prostate cancer: results from a randomized trial
    Moshe Shike
    Memorial Sloan Kettering Cancer Center, New York, NY, and National Cancer Institute, Bethesda, MD
    J Clin Oncol 20:3592-8. 2002
    ..To determine whether a diet low in fat and high in fruits, vegetables, and fiber may be protective against prostate cancer by having an impact on serial levels of serum prostate-specific antigen (PSA)...
  31. ncbi request reprint Polyps and vegetables (and fat, fibre): the polyp prevention trial
    A Schatzkin
    National Cancer Institute, Bethesda, MD 20814, USA
    IARC Sci Publ 156:463-6. 2002
  32. ncbi request reprint A prospective study of tobacco, alcohol, and the risk of esophageal and gastric cancer subtypes
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Epidemiol 165:1424-33. 2007
    ..93, 95% CI: 2.69, 9.03) but not risk for esophageal, gastric cardia, or gastric noncardia adenocarcinoma...
  33. ncbi request reprint Reproductive factors, exogenous hormone use and bladder cancer risk in a prospective study
    Marie M Cantwell
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 119:2398-401. 2006
    ..62-2.43) and 0.57 (95% CI = 0.14-2.34), respectively, compared with nonusers (p = 0.50). Findings from this study are not consistent with the hypothesis that hormone-related factors in women are associated with bladder cancer...
  34. ncbi request reprint The polyp prevention trial continued follow-up study: no effect of a low-fat, high-fiber, high-fruit, and -vegetable diet on adenoma recurrence eight years after randomization
    Elaine Lanza
    Laboratory for Cancer Prevention, Centre for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Room 7206, Bethesda, MD 20892 8325, USA
    Cancer Epidemiol Biomarkers Prev 16:1745-52. 2007
    ..04 (0.98-1.09). This study failed to show any effect of a low-fat, high-fiber, high-fruit and -vegetable eating pattern on adenoma recurrence even with 8 years of follow-up. (Cancer Epidemiol Biomarkers Prev 2007;16(9):1745-52)...
  35. pmc Male predominance of upper gastrointestinal adenocarcinoma cannot be explained by differences in tobacco smoking in men versus women
    N D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Eur J Cancer 46:2473-8. 2010
    ..As smoking is a well-established risk factor, we investigated the role of tobacco smoking in the male predominance of UGI adenocarcinomas in the United States NIH-AARP Diet and Health Study...
  36. ncbi request reprint Dietary fat, fat subtypes, and breast cancer in postmenopausal women: a prospective cohort study
    E Velie
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 92:833-9. 2000
    ..To extend the prospective epidemiologic evidence on this question, we examined the association between adult dietary intake of fat, fat subtypes, and breast cancer in a large, prospective cohort of postmenopausal women...
  37. pmc Accelerometer-measured physical activity in Chinese adults
    Tricia M Peters
    National Cancer Institute, Bethesda, Maryland, USA
    Am J Prev Med 38:583-91. 2010
    ..Following adoption of a Western lifestyle, China is experiencing a decline in physical activity levels, which is projected to contribute to future increases in the burden of chronic diseases...
  38. ncbi request reprint Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 122:2330-6. 2008
    ..Results from this large prospective observational study are consistent with previous case-control studies and support the hypothesis that total fruit and vegetable intake is associated with reduced risk of head and neck cancer...
  39. pmc Physical activity and esophageal and gastric carcinoma in a large prospective study
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Prev Med 36:112-9. 2009
    ..Few studies have investigated the relationship of physical activity to esophageal and gastric carcinoma according to histology and anatomic site...
  40. ncbi request reprint Prospective investigation of the cigarette smoking-head and neck cancer association by sex
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland 20852, USA
    Cancer 110:1593-601. 2007
    ..Very few prospective studies have examined the association between cigarette smoking and cancers of the head and neck in women, even though the rates of smoking in women are increasing rapidly worldwide...
  41. ncbi request reprint Empirical evidence of correlated biases in dietary assessment instruments and its implications
    V Kipnis
    Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7354, USA
    Am J Epidemiol 153:394-403. 2001
    ..3 times larger study than would be estimated by the standard approach. The implications of the results for the ability of FFQ-based epidemiologic studies to detect important diet-disease associations are discussed...
  42. doi request reprint Index-based dietary patterns and risk of colorectal cancer: the NIH-AARP Diet and Health Study
    J Reedy
    Risk Factor Monitoring and Methods Branch, Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
    Am J Epidemiol 168:38-48. 2008
    ..Index-based dietary patterns that are consistent with given dietary guidelines are associated with reduced risk...
  43. pmc Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention Trial
    G Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Building 576, Room 101, 1050 Boyles Street, Frederick, MD 21702, USA
    Br J Cancer 103:1453-61. 2010
    ..Flavonols, bioactive compounds found in plant-based foods and beverages, may inhibit colorectal neoplasms partly by attenuating inflammation...
  44. ncbi request reprint Association of genetic variants in the calcium-sensing receptor with risk of colorectal adenoma
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    Cancer Epidemiol Biomarkers Prev 13:2181-6. 2004
    ..We assessed the associations between CASR gene variants and risk for colorectal adenoma, a cancer precursor. We further investigated gene-diet interactions between the CASR variants and calcium intake on adenoma risk...
  45. ncbi request reprint Comparison of estimated renal net acid excretion from dietary intake and body size with urine pH
    Dominique S Michaud
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, 6120 Executive Boulevard, EPS 320 MSC 7232, Bethesda, MD 20892 7232, USA
    J Am Diet Assoc 103:1001-7; discussion 1007. 2003
    ..The aim of this study was to examine whether estimated net acid excretion (NAE) from two dietary assessment instruments can predict urine pH in healthy volunteers...
  46. pmc Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
    BMC Cancer 9:349. 2009
    ..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
  47. ncbi request reprint Lifetime weight history and endometrial cancer risk by type of menopausal hormone use in the NIH-AARP diet and health study
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Suite 320, Executive Plaza South, MSC7232, Bethesda, MD 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 16:723-30. 2007
    ..We conclude that both current adiposity and adult weight gain are associated with substantial increases in the risk of endometrial cancer, with relations particularly evident among never users of menopausal hormone therapy...
  48. pmc Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women
    Unhee Lim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
    Gastroenterology 134:47-55. 2008
    ..We examined genomic methylation of leukocyte DNA in relation to colorectal adenoma (CRA) among asymptomatic women (40-79 years of age) participating in a multicenter colonoscopy screening study (CONCeRN Study, 2000-2002)...
  49. ncbi request reprint Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 109:675-84. 2007
    ..Adiposity has been linked inconsistently with prostate cancer, and few studies have evaluated whether such associations vary by disease aggressiveness...
  50. ncbi request reprint Dietary fiber intake: assessing the degree of agreement between food frequency questionnaires and 4-day food records
    Tamaro S Hudson
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 8329, USA
    J Am Coll Nutr 25:370-81. 2006
    ....
  51. pmc Hormonal and reproductive factors and risk of postmenopausal thyroid cancer in the NIH-AARP Diet and Health Study
    S J Schonfeld
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Cancer Epidemiol 35:e85-90. 2011
    ..While this suggests a possible etiologic role of female sex hormones, clear associations between hormonal and reproductive factors and thyroid cancer have not been observed. However, few large prospective studies have been conducted...
  52. ncbi request reprint Meat intake and the recurrence of colorectal adenomas
    A Mathew
    Nutritional Epidemiology Branch, Division of Epidemiologya nd Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Eur J Cancer Prev 13:159-64. 2004
    ....
  53. ncbi request reprint Measuring cell proliferation in the rectal mucosa. comparing bromodeoxyuridine (BrdU) and proliferating cell nuclear antigen (PCNA) assays
    M Kulldorff
    National Cancer Institute, Bethesda, MD, USA
    J Clin Epidemiol 53:875-83. 2000
    ..When used in a clinical or epidemiological setting, it is important to take multiple biopsies at multiple time points...
  54. ncbi request reprint Insulin resistance-related genes and advanced left-sided colorectal adenoma
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:703-8. 2007
    ....
  55. ncbi request reprint High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection program
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:315-20. 2006
    ..Although substantial evidence suggests that smoking is a strong effect modifier for other antioxidative nutrients, little is known about smoking-selenium interactions in colorectal tumors...
  56. pmc Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  57. ncbi request reprint Meat, fat, and their subtypes as risk factors for colorectal cancer in a prospective cohort of women
    Andrew Flood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 158:59-68. 2003
    ..This study provided no evidence of an association between either meat or fat (or any of their subtypes) and colorectal cancer incidence, but the authors cannot rule out the possibility of a modest association...
  58. ncbi request reprint Dietary fibre and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort
    Volker Mai
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
    Int J Epidemiol 32:234-9. 2003
    ..We investigated the association between dietary fibre intake and risk of CRC in a cohort of women that prospectively answered a food frequency questionnaire (FFQ)...
  59. pmc Adiposity in relation to colorectal adenomas and hyperplastic polyps in women
    Michael F Leitzmann
    The Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Cancer Causes Control 20:1497-507. 2009
    ..To examine whether BMI is independently related to colorectal adenomas and hyperplastic polyps...
  60. pmc Vitamin E intake and risk of esophageal and gastric cancers in the NIH-AARP Diet and Health Study
    Sarah Carman
    NEB DCEG, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Int J Cancer 125:165-70. 2009
    ..An increase of 71 mg/day (half the interquartile range) in supplemental vitamin E had an hazard ratio (95% confidence interval) of 0.92 (0.85-1.00) and the p value for trend in the quartile analysis was 0.015...
  61. ncbi request reprint Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms
    Volker Mai
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892 7105, USA
    Cancer Res 63:1752-5. 2003
    ..We conclude that dietary interventions can partially offset genetic susceptibility to intestinal carcinogenesis...
  62. ncbi request reprint Physical activity and risk of endometrial cancer in a prospective cohort study (United States)
    Lisa H Colbert
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD, USA
    Cancer Causes Control 14:559-67. 2003
    ..To examine the physical activity and endometrial cancer relationship in a prospective study of US women enrolled in the Breast Cancer Detection Demonstration Project (BCDDP) Follow-up Study...
  63. pmc Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study
    J Q Lew
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD, USA
    Br J Cancer 104:537-41. 2011
    ..The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear...
  64. pmc Tea, coffee, carbonated soft drinks and upper gastrointestinal tract cancer risk in a large United States prospective cohort study
    J S Ren
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States
    Eur J Cancer 46:1873-81. 2010
    ..In summary, hot tea intake was inversely associated with pharyngeal cancer, and coffee was directly associated with gastric cardia cancer, but was inversely associated with EADC during some follow-up periods...
  65. doi request reprint Components of variation in serum carotenoid concentrations: the Polyp Prevention Trial
    M R Forman
    Laboratory of Biosystems and Cancer, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Eur J Clin Nutr 63:763-70. 2009
    ..The intra- and interindividual variations and season and center effects were estimated from a series of serum carotenoid concentrations in the Polyp Prevention Trial (PPT) participants...
  66. ncbi request reprint Epidemiological studies of cereals, fruit and vegetables
    A Schatzkin
    National Cancer Institute, Bethesda, MD 20814, USA
    IARC Sci Publ 156:77. 2002
  67. pmc Smoking duration, intensity, and risk of Parkinson disease
    H Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr, PO Box 12233, Mail Drop A3 05, Research Triangle Park, NC 27709, USA
    Neurology 74:878-84. 2010
    ..To evaluate the relative importance of smoking duration vs intensity in reducing the risk of Parkinson disease (PD)...
  68. doi request reprint Waist circumference and mortality
    Annemarie Koster
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Epidemiol 167:1465-75. 2008
    ..36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI...
  69. ncbi request reprint Using intake biomarkers to evaluate the extent of dietary misreporting in a large sample of adults: the OPEN study
    Amy F Subar
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 158:1-13. 2003
    ..There was little underreporting of the percentage of energy from protein for men or women. These findings have important implications for nutritional epidemiology and dietary surveillance...
  70. ncbi request reprint Association of energy intake and energy balance with postmenopausal breast cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, National Cancer Institute, Executive Plaza South, Suite 320, MSC7232, Bethesda, Maryland 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 15:334-41. 2006
    ..In addition, these three aspects of energy balance may act jointly in determining breast cancer risk...
  71. pmc Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial
    Gwen Murphy
    Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 124:2148-51. 2009
    ..Increased risk of adenoma recurrence as conferred by DRD2 genotypes may be related to difference in alcohol and fat intake across genotypes...
  72. pmc Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 ExecutiveBoulevard, MSC 7232, Rockville, MD 20852, USA
    Lancet Oncol 9:649-56. 2008
    ..To address this question, we aimed to compare incidence rates of lung cancer by stratum of smoking use in men and women of the National Institutes of Health (NIH)-AARP cohort...
  73. pmc Age-specific physical activity and prostate cancer risk among white men and black men
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 115:5060-70. 2009
    ..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men...
  74. pmc Physical activity and head and neck cancer risk
    Michael F Leitzmann
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Causes Control 19:1391-9. 2008
    ..To investigate the relation of physical activity to head and neck cancer...
  75. pmc Physical activity in relation to total, advanced, and fatal prostate cancer
    Steven C Moore
    Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008
    ..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort...
  76. pmc Dietary meat intake in relation to colorectal adenoma in asymptomatic women
    Leah M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Gastroenterol 104:1231-40. 2009
    ....
  77. pmc Reproductive factors, exogenous hormone use and risk of lymphoid neoplasms among women in the National Institutes of Health-AARP Diet and Health Study Cohort
    Lindsay M Morton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Int J Cancer 124:2737-43. 2009
    ..These data do not support an important role for reproductive factors or exogenous hormones in modulating lymphomagenesis...
  78. ncbi request reprint Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal women
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 14:1724-31. 2005
    ..However, endometrial carcinoma risks among estrogen plus progestin users and among former unopposed estrogen users are not firmly established...
  79. ncbi request reprint Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health Study
    Yikyung Park
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Am J Epidemiol 166:1270-9. 2007
    ..04). Although the authors cannot definitively rule out a weak association for aggressive prostate cancer, their findings do not provide strong support for the hypothesis that calcium and dairy foods increase prostate cancer risk...
  80. ncbi request reprint Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women
    Karen Woodson
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Natl Cancer Inst 96:407-10. 2004
    ..These findings are intriguing and need to be confirmed in larger studies...
  81. doi request reprint Use of the predictive sugars biomarker to evaluate self-reported total sugars intake in the Observing Protein and Energy Nutrition (OPEN) study
    Natasa Tasevska
    Applied Research Program, Division of Cancer Control and Population Sciences, Nutritional Epidemiology, Branch, National Cancer Institute, 6130 Executive Blvd, EPN 3121, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 20:490-500. 2011
    ..A predictive biomarker for intake of total sugars was recently developed under controlled conditions. We used this biomarker to assess measurement error (ME) structure in self-reported intake of total sugars in free-living individuals...
  82. pmc Obesity and thyroid cancer risk among U.S. men and women: a pooled analysis of five prospective studies
    Cari M Kitahara
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:464-72. 2011
    ..Thyroid cancer incidence has risen dramatically in the United States since the early 1980s. Although the prevalence of obesity has doubled during this time period, the relationship between obesity and thyroid cancer is uncertain...
  83. ncbi request reprint Adenomatous polyp recurrence and physical activity in the Polyp Prevention Trial (United States)
    Lisa H Colbert
    National Institute on Aging, Bethesda, MD, USA
    Cancer Causes Control 13:445-53. 2002
    ..To examine prospectively the association between physical activity and adenomatous polyp recurrence...
  84. ncbi request reprint Adiposity, adult weight change, and postmenopausal breast cancer risk
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Arch Intern Med 167:2091-102. 2007
    ..Obesity is a risk factor for postmenopausal breast cancer, but the role of the timing and amount of adult weight change in breast cancer risk is unclear...
  85. pmc Physical activity and postmenopausal breast cancer risk in the NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7232, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:289-96. 2009
    ..Although physical activity has been associated with reduced breast cancer risk, whether this association varies across breast cancer subtypes or is modified by reproductive and lifestyle factors is unclear...
  86. ncbi request reprint Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007
    ..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
  87. pmc Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk
    Hui Lee Wong
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    Eur J Cancer 46:2457-66. 2010
    ..Fat intake modified the APC D1822V-adenoma association, but further studies are warranted...
  88. ncbi request reprint Physical activity and the risk of colon cancer among women: a prospective cohort study (United States)
    Brook A Calton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Int J Cancer 119:385-91. 2006
    ..The results of this large prospective cohort study among women do not support the hypothesis that physical activity is related to a lower incidence of colon cancer...
  89. pmc Diet and cancer: future etiologic research
    A Schatzkin
    Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 103:171-5. 1995
    ..Finally, we briefly review strategies for evaluating promising hypotheses linking diet to cancers of the large bowel, lung, breast, and prostate...
  90. pmc Physical activity, sedentary behaviours, and the prevention of endometrial cancer
    S C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Br J Cancer 103:933-8. 2010
    ..Taken together with the established biological plausibility of this relation, the totality of evidence now convincingly indicates that physical activity prevents or reduces risk of endometrial cancer...
  91. pmc Serum sex hormone levels are related to breast cancer risk in postmenopausal women
    J F Dorgan
    Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland 20892 7326, USA
    Environ Health Perspect 105:583-5. 1997
    ..2 (95% CI = 2.0-19.0). Our results lend considerable support to the hypothesis that serum concentrations of estrogens and androgens are related to the subsequent diagnosis of breast cancer in postmenopausal women...
  92. pmc Past body mass index and risk of mortality among women
    S C Moore
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Obes (Lond) 32:730-9. 2008
    ..Analysis of BMI from an earlier time period may minimize reverse causation without requiring exclusion of participants based on disease or smoking history...
  93. pmc Alcohol intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study
    C L Meinhold
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120Executive Boulevard, Rockville, MD 20852, USA
    Br J Cancer 101:1630-4. 2009
    ..Certain studies suggest that alcohol may reduce the risk of thyroid cancer in women, but the effect in men remains unclear...
  94. pmc Alcohol and head and neck cancer risk in a prospective study
    N D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Executive Plaza North, Suite 3109, 6130 Executive Boulevard, MSC 7361, Bethesda, MD 20892 7361, USA
    Br J Cancer 96:1469-74. 2007
    ..7), men (34.4). In summary, drinking >3 alcoholic beverages per day was associated with increased risk in men and women, but consumption of up to one drink per day may be associated with reduced risk relative to non-drinking...
  95. ncbi request reprint Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2160-7. 2005
    ..Associations for total fruits and vegetables were similar for different histologic types. These results suggest that fruit and vegetable consumption in adulthood has no important association with the risk of ovarian cancer...
  96. ncbi request reprint Carbohydrate, glycemic index, and glycemic load and colorectal adenomas in the Prostate, Lung, Colorectal, and Ovarian Screening Study
    Andrew Flood
    University of Minnesota, Minneapolis, MN, Henry Ford Hospital, Detroit, MI, USA
    Am J Clin Nutr 84:1184-92. 2006
    ..It is possible that high-glycemic-load diets, through their hyperinsulinemic effects, can increase the risk of colorectal cancer...
  97. doi request reprint Using biomarker data to adjust estimates of the distribution of usual intakes for misreporting: application to energy intake in the US population
    Rivka Yanetz
    Department of Mathematics, Bar Ilan University, Ramat Gan, Israel
    J Am Diet Assoc 108:455-64; discussion 464. 2008
    ....
  98. ncbi request reprint Low energy reporting may increase in intervention participants enrolled in dietary intervention trials
    Bette Caan
    Division of Research, Kaiser Permanente Medical Care Program of Northern California, 2000 Broadway, Oakland, CA 94612, USA
    J Am Diet Assoc 104:357-66; quiz 491. 2004
    ..To examine differences in low energy intake reporting between intervention and control groups during a dietary intervention trial...
  99. ncbi request reprint Diet, nutrition and the prevention of cancer
    Timothy J Key
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, UK
    Public Health Nutr 7:187-200. 2004
    ..To assess the epidemiological evidence on diet and cancer and make public health recommendations...
  100. ncbi request reprint Dietary manipulation, ethnicity, and serum PSA levels
    James A Eastham
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Urology 62:677-82. 2003
    ....
  101. ncbi request reprint Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies
    Satu Mannisto
    National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 165:246-55. 2007
    ..00). The associations observed were generally similar across studies, for both sexes, and for colon cancer and rectal cancer. These pooled data did not suggest that carotenoids play an important role in the etiology of colorectal cancer...