Research Topics
Species | C SchairerSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
A prospective study of physical activity and the risk of pancreatic cancer among women (United States)Brook A Calton
Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
BMC Cancer 8:63. 2008..Several epidemiologic studies have examined the association between physical activity and pancreatic cancer risk; however, the results of these studies are not consistent...
Serum concentrations of estrogens, sex hormone binding globulin, and androgens and risk of breast hyperplasia in postmenopausal womenCatherine Schairer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS, Room 8020 MSC 7234, Rockville, MD 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 14:1660-5. 2005..We sought to determine whether serum concentrations of estrogens, androgens, and sex hormone binding globulin in postmenopausal women were related to the presence of mammary hyperplasia, an established breast cancer risk factor...
Probabilities of death from breast cancer and other causes among female breast cancer patientsCatherine Schairer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
J Natl Cancer Inst 96:1311-21. 2004..We used data on breast cancer patients from the Surveillance, Epidemiology, and End Results (SEER) Program in a competing-risk analysis...
Comparative mortality for 621 second cancers in 29356 testicular cancer survivors and 12420 matched first cancersCatherine Schairer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Natl Cancer Inst 99:1248-56. 2007..However, no data on outcomes of testicular cancer survivors with second cancers compared to patients with comparable first cancers exist...
Inflammatory breast cancer: high risk of contralateral breast cancer compared to comparably staged non-inflammatory breast cancerCatherine Schairer
Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7244, USA
Breast Cancer Res Treat 129:117-24. 2011..In conclusion, our results suggest that IBC has higher risk of cancer in the contralateral breast than comparably staged non-IBC, possibly due to both metastatic/recurrent disease and independent primaries...
Circulating insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 levels and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohortCatherine Schairer
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, 20852 7244, USA
Horm Cancer 1:100-11. 2010..Further research should emphasize larger studies, including pooled analyses, analyses by cancer subtype, improved exposure assessment, and possible mechanisms...
Serum concentrations of IGF-I, IGFBP-3 and c-peptide and risk of hyperplasia and cancer of the breast in postmenopausal womenCatherine Schairer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Int J Cancer 108:773-9. 2004..5 (95% CI 0.7-3.0) and 1.6 (95% CI 0.8-3.2), respectively (p trend = 0.35 and 0.25, respectively). Our results suggest that insulin and insulin resistance may play a role in breast pathology in postmenopausal women...
Suicide after breast cancer: an international population-based study of 723,810 womenCatherine Schairer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Rm 8020, MSC 7244, Rockville, MD 20852 7244, USA
J Natl Cancer Inst 98:1416-9. 2006..08) and remained elevated among women diagnosed between 1990 and 2001 (SMR = 1.36, 95% CI = 1.18 to 1.57). The cumulative probability of suicide was 0.20% 30 years after breast cancer diagnosis...
Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer riskC Schairer
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852 7234, USA
JAMA 283:485-91. 2000..Whether menopausal hormone replacement therapy using a combined estrogen-progestin regimen increases risk of breast cancer beyond that associated with estrogen alone is unknown...
Progesterone receptors--animal models and cell signalling in breast cancer. Implications for breast cancer of inclusion of progestins in hormone replacement therapiesCatherine Schairer
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Rockville, Maryland 20852, USA
Breast Cancer Res 4:244-8. 2002....
Physical activity and risk of ovarian cancer: a prospective cohort study in the United StatesLindsay M Hannan
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS-MSC 7232, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 13:765-70. 2004..13). In this prospective cohort study among U.S. women, we found no overall significant association between physical activity and risk of ovarian cancer, although the results are suggestive of an inverse association...
Dietary fat, fat subtypes, and breast cancer in postmenopausal women: a prospective cohort studyE Velie
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 92:833-9. 2000..To extend the prospective epidemiologic evidence on this question, we examined the association between adult dietary intake of fat, fat subtypes, and breast cancer in a large, prospective cohort of postmenopausal women...
Breast cancer risk in elderly women with systemic autoimmune rheumatic diseases: a population-based case-control studyS M Gadalla
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Br J Cancer 100:817-21. 2009..49, 95% CI=0.26-0.93) among women with SLE. These findings suggest that systemic inflammation may affect breast epithelial neoplasia...
Estrogen replacement therapy and breast cancer survival in a large screening studyC Schairer
Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7374, USA
J Natl Cancer Inst 91:264-70. 1999..We examined breast cancer mortality among women who were diagnosed with axillary lymph node-negative and node-positive breast cancer according to the currency of estrogen use at diagnosis...
Prospective study of physical activity and risk of postmenopausal breast cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Breast Cancer Res 10:R92. 2008..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
Reproductive factors, exogenous hormone use and bladder cancer risk in a prospective studyMarie M Cantwell
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Int J Cancer 119:2398-401. 2006..62-2.43) and 0.57 (95% CI = 0.14-2.34), respectively, compared with nonusers (p = 0.50). Findings from this study are not consistent with the hypothesis that hormone-related factors in women are associated with bladder cancer...
Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohortsLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 21:1305-14. 2010..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
Risk of breast, ovary, and uterine corpus cancers among 85,268 women with AIDSJ J Goedert
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Br J Cancer 95:642-8. 2006..003), approaching the risk of the general population. We conclude that the cancer deficit reflected direct or indirect effects of HIV/AIDS and that anti-HIV therapy reduced these effects...
Comparison of industrial hygienists' exposure evaluations for an epidemiologic studyP A Stewart
Environmental Epidemiology Program, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
Scand J Work Environ Health 26:44-51. 2000..A study was conducted to determine what level of information is required by industrial hygienists before they can develop exposure estimates comparable with those developed from a more in-depth evaluation...
Weight, height, and body mass index and risk for ovarian cancer in a cohort studyJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville 20852 7234, MD
Ann Epidemiol 16:869-76. 2006..Reported associations between ovarian cancer and body size are inconsistent. We assessed ovarian cancer and anthropometry in the Breast Cancer Detection Demonstration Project Follow-Up Study...
Risk of second non-hematological malignancies among 376,825 breast cancer survivorsLinda Morris Brown
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, MSC 7244, Bethesda, MD 20892 7244, USA
Breast Cancer Res Treat 106:439-51. 2007....
Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohortRachael Z Stolzenberg-Solomon
National Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health Human Services, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 16:2664-75. 2007..006) increased risk in men and women combined. These findings support the hypothesis that meat intake, particularly meat cooked at high temperatures and associated mutagens, may play a role in pancreatic cancer development...
Adiposity, physical activity, and pancreatic cancer in the National Institutes of Health-AARP Diet and Health CohortRachael Z Stolzenberg-Solomon
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Am J Epidemiol 167:586-97. 2008..53, 95% CI: 1.13, 5.65; p(trend) = 0.04) in women but not men. The authors observed no association with physical activity. Their results suggest a positive association between adiposity and pancreatic cancer...
Obesity and thyroid cancer risk among U.S. men and women: a pooled analysis of five prospective studiesCari M Kitahara
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 20:464-72. 2011..Thyroid cancer incidence has risen dramatically in the United States since the early 1980s. Although the prevalence of obesity has doubled during this time period, the relationship between obesity and thyroid cancer is uncertain...
Hormone-related risk factors and postmenopausal breast cancer among nulliparous versus parous women: An aggregated studySara J Schonfeld
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Am J Epidemiol 173:509-17. 2011..Although the baseline risk is higher for nulliparous women compared with parous women, these results suggest that the associations between hormone-related factors and breast cancer do not differ by parity...
Bone fractures and incident epithelial ovarian cancer in a prospective cohort studyKim N Danforth
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
J Womens Health (Larchmt) 18:1777-82. 2009..However, associations between fractures and ovarian cancer, another hormonal cancer, have not been examined. Therefore, we conducted a prospective study among women in the Breast Cancer Detection Demonstration Project Follow-up Study...
Energy intake and risk of postmenopausal breast cancer: an expanded analysis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohortLaura Y Sue
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 18:2842-50. 2009....
Alcohol use and risk of pancreatic cancer: the NIH-AARP Diet and Health StudyLi Jiao
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Am J Epidemiol 169:1043-51. 2009..41, 95% CI: 1.01, 2.00). These findings suggest a moderately increased pancreatic cancer risk with heavy alcohol use, particularly liquor; however, residual confounding by cigarette smoking cannot be completely excluded...
Medication use and risk of ovarian carcinoma: a prospective studyJames V Lacey
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852 7234, USA
Int J Cancer 108:281-6. 2004..5) appeared to increase risk. In our study, neither anti-inflammatory medications nor anti-psychotic medications were associated with ovarian cancer. Potential associations with histamine-receptor antagonists may warrant further study...
Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal womenJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 14:1724-31. 2005..However, endometrial carcinoma risks among estrogen plus progestin users and among former unopposed estrogen users are not firmly established...
Dietary fibre and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohortVolker Mai
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Int J Epidemiol 32:234-9. 2003..We investigated the association between dietary fibre intake and risk of CRC in a cohort of women that prospectively answered a food frequency questionnaire (FFQ)...
Epidemiology of inflammatory breast cancer (IBC)William F Anderson
DHHS NIH NCI DCP, Rockville, MD 20852 7244, USA
Breast Dis 22:9-23. 2005..We also incorporate emerging data from the National Cancer Institute's (NCI) Surveillance, Epidemiology, and End Results (SEER) Program...
Menopausal hormone replacement therapy and risk of ovarian cancerJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, MSC 7234, Rockville, MD 20852, USA
JAMA 288:334-41. 2002..The association between menopausal hormone replacement therapy and ovarian cancer is unclear...
Rapidly increasing incidence of ocular non-hodgkin lymphomaRoxana Moslehi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
J Natl Cancer Inst 98:936-9. 2006..By contrast, other NHLs showed evidence of peaking in recent years. The distinctive patterns of ocular NHL call for further studies to identify risk factors and mechanisms, including the potential role of C. psittaci or other infections...
Folate, methionine, alcohol, and colorectal cancer in a prospective study of women in the United StatesAndrew Flood
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, MSC 7232, Bethesda, MD 20892, USA
Cancer Causes Control 13:551-61. 2002..We investigated the associations of folate, methionine, and alcohol intake, as well as combinations of these factors, with risk of colorectal cancer (CRC)...
Fruit and vegetable intakes and the risk of colorectal cancer in the Breast Cancer Detection Demonstration Project follow-up cohortAndrew Flood
Division of Cancer Epidemiology and Genetics, The National Cancer Institute, Bethesda, MD 20892, USA
Am J Clin Nutr 75:936-43. 2002..Recent findings have cast doubt on the hypothesis that high intakes of fruit and vegetables are associated with a reduced risk of colorectal cancer...
Secular stability and reliability of measurements of the percentage of dense tissue on mammogramsJacques Benichou
Department of Biostatistics, University of Rouen Medical School and Rouen University Hospital, 76031 Rouen Cedex, France
Cancer Detect Prev 27:266-74. 2003..Among women who developed breast cancer, the baseline mammographic density of the ipsilateral (diseased) breast was 0.53 (95% confidence interval (CI) 0.20-0.86) percentage units higher than in the contralateral breast...
Meat, fat, and their subtypes as risk factors for colorectal cancer in a prospective cohort of womenAndrew Flood
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 158:59-68. 2003..This study provided no evidence of an association between either meat or fat (or any of their subtypes) and colorectal cancer incidence, but the authors cannot rule out the possibility of a modest association...
The etiology of uterine sarcomas: a pooled analysis of the epidemiology of endometrial cancer consortiumA S Felix
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
Br J Cancer 108:727-34. 2013..We also examined risk factor associations for malignant mixed mullerian tumours (MMMTs) and endometrioid endometrial carcinomas (EECs) for comparison purposes...
Past body mass index and risk of mortality among womenS C Moore
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Obes (Lond) 32:730-9. 2008..Analysis of BMI from an earlier time period may minimize reverse causation without requiring exclusion of participants based on disease or smoking history...
Family history of breast cancer as a risk factor for ovarian cancer in a prospective studyNeely Kazerouni
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852-7234, USA
Cancer 107:1075-83. 2006..2; 95% CI = 1.7-10). CONCLUSIONS: A detailed breast cancer family history as well as an individual's age and personal history of breast cancer are useful for identifying women at elevated genetic risk of ovarian cancer...
Physical activity and risk of endometrial cancer in a prospective cohort study (United States)Lisa H Colbert
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD, USA
Cancer Causes Control 14:559-67. 2003..To examine the physical activity and endometrial cancer relationship in a prospective study of US women enrolled in the Breast Cancer Detection Demonstration Project (BCDDP) Follow-up Study...
Diet quality and subsequent cancer incidence and mortality in a prospective cohort of womenVolker Mai
Division of Cancer Epidemiology and Genetics, National Cancer Institute/NIH, Bethesda, MD 20892, USA
Int J Epidemiol 34:54-60. 2005..Incidence was only decreased for lung cancers. These observations are consistent with the hypothesis that a high RFS dietary pattern, or associated lifestyle factors, might affect cancer progression and survival...
Physical activity and the risk of colon cancer among women: a prospective cohort study (United States)Brook A Calton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Int J Cancer 119:385-91. 2006..The results of this large prospective cohort study among women do not support the hypothesis that physical activity is related to a lower incidence of colon cancer...
Population-density and county-level variation in breast cancer mortality rates among white women residing in the Northeastern and Southern United StatesSusan R Sturgeon
Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
Cancer Causes Control 14:923-31. 2003..We assessed the contribution of variation in risk factor prevalence to population-density and county-level variation in breast cancer mortality rates...
Calcium from diet and supplements is associated with reduced risk of colorectal cancer in a prospective cohort of womenAndrew Flood
Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
Cancer Epidemiol Biomarkers Prev 14:126-32. 2005..e., diet or supplements)...
Serum concentrations of estrogens, sex hormone-binding globulin, and androgens and risk of breast cancer in postmenopausal womenLaila Adly
Department of Epidemiology and Biostatistics, School of Public Health and Health Services, George Washington University, Washington, DC, USA
Int J Cancer 119:2402-7. 2006..6 (95% CI 0.7-3.6); p-trend = 0.13). Higher serum concentrations of estrogens were associated with increased breast cancer risk in postmenopausal women. Androgen levels were not independently associated with substantially increased risk...
Empirically derived dietary patterns and risk of postmenopausal breast cancer in a large prospective cohort studyEllen M Velie
Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing 48824, USA
Am J Clin Nutr 82:1308-19. 2005..Inconsistent associations have been reported between diet and breast cancer...
Dietary carbohydrate, glycemic index, and glycemic load and the risk of colorectal cancer in the BCDDP cohortLori Strayer
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
Cancer Causes Control 18:853-63. 2007..Case-control studies support this hypothesis, but prospective cohorts have had mixed results...
Relationship between calcium, lactose, vitamin D, and dairy products and ovarian cancerDaniel O Koralek
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Nutr Cancer 56:22-30. 2006..The possibility of a decreased risk of ovarian cancer for dietary calcium merits further evaluation...
Projecting absolute invasive breast cancer risk in white women with a model that includes mammographic densityJinbo Chen
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Natl Cancer Inst 98:1215-26. 2006..CONCLUSIONS: This new model for absolute invasive breast cancer risk in white women promises modest improvements in discriminatory power compared with the Gail model but needs to be validated with independent data...
Trends in breast cancer mortality rates by region of the United States, 1950-1999Susan R Sturgeon
School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
Cancer Causes Control 15:987-95. 2004..Limited information is available on trends in breast cancer mortality by region of the country...
