Research Topics
| Carl F SchaeferSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
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Detail Information
Publications
Pathway databasesCarl F Schaefer
Center for Bioinformatics, National Cancer Institute, National Institutes of Health, 6116 Executive Boulevard, Suite 403, Rockville, MD 20852, USA
Ann N Y Acad Sci 1020:77-91. 2004..Computable representations of pathways provide a basis for various analyses, including detection of broad network patterns, comparison with mRNA or protein abundance, and simulation...
The cancer genome anatomy project: online resources to reveal the molecular signatures of cancerRobert L Strausberg
National Cancer Institute, Bethesda, MD 20892, USA
Cancer Invest 20:1038-50. 2002
Identification of microbial DNA in human cancerChristopher G Duncan
Preston Robert Tisch Brain Tumor Center, Pediatric Brain Tumor Foundation Institute, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
BMC Med Genomics 2:22. 2009..CONCLUSION: DK-MICROBE can identify previously unknown infectious agents in human tumors, and is now available for further applications for the identification of pathogen DNA in human cancer and other diseases...
PID: the Pathway Interaction DatabaseCarl F Schaefer
National Cancer Institute, Center for Biomedical Informatics and Information Technology, Rockville MD, USA
Nucleic Acids Res 37:D674-9. 2009..The database is updated with new pathway content every month and supplemented by specially commissioned articles on the practical uses of other relevant online tools...
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequencesRobert L Strausberg
National Cancer Institute, Bethessda, MD 20892 2580, USA
Proc Natl Acad Sci U S A 99:16899-903. 2002..All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http:mgc.nci.nih.gov)...
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinomaJoseph Riss
Laboratory of Biosystems and Cancer, Comparative Oncology Program, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 66:7216-24. 2006..The observations reported here provide a conceptual framework for further efforts to understand the biology and to develop more effective diagnostic biomarkers and therapeutic strategies for renal tumors and renal ischemia...
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)Daniela S Gerhard
Genome Res 14:2121-7. 2004..Recently, a rat cDNA component was added to the project, and ongoing frog (Xenopus) and zebrafish (Danio) cDNA projects were expanded to take advantage of the high-throughput MGC pipeline...
An anatomy of normal and malignant gene expressionKathy Boon
Duke University Medical Center, Durham, NC 27710, USA
Proc Natl Acad Sci U S A 99:11287-92. 2002..We report here an easily accessible view of nearly any gene's expression in a wide variety of malignant and normal tissues...
