B C Schaefer

Summary

Affiliation: National Jewish Medical and Research Center
Country: USA

Publications

  1. ncbi request reprint Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor
    B C Schaefer
    Howard Hughes Medical Institute and Department of Medicine, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Immunity 11:411-21. 1999
  2. ncbi request reprint Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo
    B C Schaefer
    National Jewish Medical and Research Center, 1400 Jackson Street, K512, Denver, Colorado 80206, USA
    Cell Immunol 214:110-22. 2001
  3. pmc Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling
    T K Teague
    Department of Medicine, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    J Exp Med 191:915-26. 2000
  4. ncbi request reprint Genomic-scale analysis of gene expression in resting and activated T cells
    P Marrack
    Departments of Biochemistry and Molecular Biology, Immunology and Medicine, Howard Hughes Medical Institute, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Curr Opin Immunol 12:206-9. 2000
  5. ncbi request reprint MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway
    W Sun
    Department of Pharmacology, University of Colorado Health Sciences Center and University of Colorado Cancer Center, Denver, CO 80262, USA
    J Biol Chem 276:5093-100. 2001
  6. ncbi request reprint Homeostasis of alpha beta TCR+ T cells
    P Marrack
    Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Nat Immunol 1:107-11. 2000
  7. ncbi request reprint Immunological adjuvants promote activated T cell survival via induction of Bcl-3
    T C Mitchell
    Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Nat Immunol 2:397-402. 2001
  8. ncbi request reprint A novel family of retroviral vectors for the rapid production of complex stable cell lines
    B C Schaefer
    National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Anal Biochem 297:86-93. 2001

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor
    B C Schaefer
    Howard Hughes Medical Institute and Department of Medicine, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Immunity 11:411-21. 1999
    ..Live cell fluorescence imaging thus enables characterization of signal transducers that are dynamically translocated following TCR engagement...
  2. ncbi request reprint Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo
    B C Schaefer
    National Jewish Medical and Research Center, 1400 Jackson Street, K512, Denver, Colorado 80206, USA
    Cell Immunol 214:110-22. 2001
    ..Dendritic cells undergo specific morphologic changes following interactions with antigen-specific T cells...
  3. pmc Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling
    T K Teague
    Department of Medicine, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    J Exp Med 191:915-26. 2000
    ..These data suggest that there is activation-induced inhibition of IL-6 receptor signaling in T cells. This inhibition appears to be specific for some but not all of the IL-6-mediated signaling cascades in these cells...
  4. ncbi request reprint Genomic-scale analysis of gene expression in resting and activated T cells
    P Marrack
    Departments of Biochemistry and Molecular Biology, Immunology and Medicine, Howard Hughes Medical Institute, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Curr Opin Immunol 12:206-9. 2000
    ..This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli...
  5. ncbi request reprint MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway
    W Sun
    Department of Pharmacology, University of Colorado Health Sciences Center and University of Colorado Cancer Center, Denver, CO 80262, USA
    J Biol Chem 276:5093-100. 2001
    ..MEKK2 and MEKK3 are differentially associated with signaling from specific upstream receptor systems, whereas both activate the MEK5-BMK1/ERK5 pathway...
  6. ncbi request reprint Homeostasis of alpha beta TCR+ T cells
    P Marrack
    Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Nat Immunol 1:107-11. 2000
    ..A case is made for the idea that the evolutionary divergence of the short-chain family allowed for concurrent divergence in leukocytes...
  7. ncbi request reprint Immunological adjuvants promote activated T cell survival via induction of Bcl-3
    T C Mitchell
    Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Nat Immunol 2:397-402. 2001
    ..Retroviral infection experiments showed that expression of Bcl-3 increased survival of activated T cells in vitro and in vivo. Adjuvants may therefore improve survival of activated T cells via induction of Bcl-3...
  8. ncbi request reprint A novel family of retroviral vectors for the rapid production of complex stable cell lines
    B C Schaefer
    National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Anal Biochem 297:86-93. 2001
    ..The use of these vectors will thus dramatically accelerate the production of complex stable cell lines...