Research Topics

Genomes and Genes


David J Sandstrom


Affiliation: National Institutes of Health
Country: USA


  1. Sandstrom D. Isoflurane reduces excitability of Drosophila larval motoneurons by activating a hyperpolarizing leak conductance. Anesthesiology. 2008;108:434-46 pubmed publisher
    ..This work provides a link between anesthetic-sensitive leak currents and presynaptic function and has generated new tools for analysis of the function of this synapse. ..
  2. Sandstrom D. Extracellular protons reduce quantal content and prolong synaptic currents at the Drosophila larval neuromuscular junction. J Neurogenet. 2011;25:104-14 pubmed publisher
    ..These phenotypes can be exploited to study the mechanisms of acid-mediated changes in neuronal function, and to pursue the way in which pH modulates synaptic function in normal and pathophysiological conditions. ..