Research Topics
Species | D P SandlerSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Indoor radon and lung cancer risk in connecticut and utahDale P Sandler
Epidemiology Branch, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
J Toxicol Environ Health A 69:633-54. 2006..While results were consistent with the estimates from studies of miners, this study provides no evidence of an increased risk for lung cancer at the exposure levels observed...
Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health StudyJennifer A Rusiecki
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Int J Cancer 118:3118-23. 2006....
Fonofos exposure and cancer incidence in the agricultural health studyRajeev Mahajan
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Environ Health Perspect 114:1838-42. 2006..A previous investigation in this cohort linked exposure to the organophosphate fonofos with incident prostate cancer in subjects with family history of prostate cancer...
Association between blood lead and the risk of amyotrophic lateral sclerosisFang Fang
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
Am J Epidemiol 171:1126-33. 2010..32). These results extend earlier findings by accounting for bone turnover in confirming the association between elevated blood lead level and higher risk of ALS...
Malathion exposure and the incidence of cancer in the agricultural health studyMatthew R Bonner
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Epidemiol 166:1023-34. 2007..Although the rate ratios for melanoma were reduced, small numbers and lack of experimental evidence suggest that the observed reductions may have arisen by chance...
Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinonLaura E Beane Freeman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Am J Epidemiol 162:1070-9. 2005..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans...
Carbaryl exposure and incident cancer in the Agricultural Health StudyRajeev Mahajan
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Int J Cancer 121:1799-805. 2007..No associations were observed with other examined cancer sites. Because the observed results were not hypothesized a priori and because of limited study of their biological plausibility, they should be interpreted with caution...
Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Am J Epidemiol 159:373-80. 2004..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study...
Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort studyMartha P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 53:486-96. 2010..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study...
Retinal degeneration in licensed pesticide applicatorsF Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Am J Ind Med 37:618-28. 2000..Retinal degeneration is the leading cause of visual impairment in older adults, but little is known about its relationship to neurotoxic exposures...
Exposure opportunities of families of farmer pesticide applicatorsB C Gladen
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 34:581-7. 1998..Families of farmer pesticide applicators have unusual opportunities for exposure, directly or indirectly, to pesticides. These exposures are not well characterized...
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health StudyJ A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3 05, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
Eur Respir J 34:1296-303. 2009..There was little evidence that allergy alone was driving these associations. In conclusion, pesticides may be an overlooked contributor to asthma risk among farmers...
Association of cigarette smoking with amyotrophic lateral sclerosisF Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Neuroepidemiology 18:194-202. 1999..The association of cigarette smoking with ALS was not affected by adjusting for alcohol use. In contrast, the weak relationship of ALS with alcohol use was apparently due to confounding by smoking...
Chronic bronchitis among nonsmoking farm women in the agricultural health studyMartin Valcin
Epidemiology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
J Occup Environ Med 49:574-83. 2007..The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women...
Pesticide use and breast cancer risk among farmers' wives in the agricultural health studyLawrence S Engel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Am J Epidemiol 161:121-35. 2005..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk...
Reduced fertility among overweight and obese menMarkku Sallmen
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
Epidemiology 17:520-3. 2006..Overweight and obese men have been reported to have lower sperm counts and hormonal changes, but data are lacking regarding effects on couple fertility...
Pendimethalin exposure and cancer incidence among pesticide applicatorsLifang Hou
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Epidemiology 17:302-7. 2006..The trends for lung cancer risk were inconsistent for different exposure metrics. CONCLUSIONS: We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites...
Characteristics of pesticide use in a pesticide applicator cohort: the Agricultural Health StudyM C Alavanja
Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, Maryland, 20892
Environ Res 80:172-9. 1999..This heterogeneity in potential exposures to pesticides between states should be useful for subsequent epidemiologic analyses using internal comparison groups...
Menstrual patterns and risk of adult-onset diabetes mellitusG S Cooper
Epidemiology Branch A3 05, National Institute of Environmental Health Sciences, PO Box 12233, Research Triangle Park, Durham, NC 27709, USA
J Clin Epidemiol 53:1170-3. 2000..These results do not support the association of long or irregular menstrual cycles with post-menopausal diabetes incidence, but do suggest a possible association of longer bleeding duration with subsequent onset of diabetes...
Neurologic symptoms in licensed pesticide applicators in the Agricultural Health StudyF Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
Hum Exp Toxicol 26:243-50. 2007..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning...
Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003M P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Am J Epidemiol 167:1235-46. 2008..Long-term exposure from handling certain pesticides, in particular, organochlorine and organophosphate insecticides, may be associated with increased risk of diabetes...
Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smokingJ A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Occup Environ Med 60:e3. 2003..Exposure to animals, their feeds, and by-products contribute to respiratory symptoms among farmers...
Lead exposure as a risk factor for amyotrophic lateral sclerosisF Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Neurodegener Dis 2:195-201. 2005..Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2- to >4-fold. However, these results may have been affected by recall bias...
Employment and work schedule are related to telomere length in womenC G Parks
Epidemiology Branch, National Institute of Environmental Health Sciences, National Insititues of Health, Research Triangle Park, NC 27599, USA
Occup Environ Med 68:582-9. 2011....
Cancer incidence in the agricultural health studyMichael C R Alavanja
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Scand J Work Environ Health 31:39-45; discussion 5-7. 2005..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture...
Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health StudyTina M Saldana
Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
Diabetes Care 30:529-34. 2007..To examine the association between pesticide use during pregnancy and gestational diabetes mellitus (GDM) among wives of licensed pesticide applicators...
Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709 2233, USA
Occup Environ Med 64:334-41. 2007..Farmer's lung, or hypersensitivity pneumonitis, is an important contributor to respiratory morbidity among farmers...
Pesticides and adult respiratory outcomes in the agricultural health studyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Healh Science, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
Ann N Y Acad Sci 1076:343-54. 2006..00-2.19) for farmers and 1.96 (95% CI = 1.05-3.66) for commercial applicators. Our wheeze results are consistent with recent animal models that support a role for organophosphates and respiratory outcomes...
Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health studyClaudine Samanic
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
Environ Health Perspect 114:1521-6. 2006..There was no apparent risk for non-Hodgkin lymphoma. CONCLUSIONS: Although associations between exposure and lung and colon cancer were observed, we did not find clear evidence for an association between dicamba exposure and cancer risk...
Pesticides associated with wheeze among commercial pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Am J Epidemiol 163:1129-37. 2006..40, 95% CI: 1.24, 4.65). These results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl...
Cigarette smoking and cancer risk: modeling total exposure and intensityJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 166:479-89. 2007..The intensity effects were statistically homogeneous, indicating that after accounting for risk from total pack-years, intensity patterns were comparable across the diverse cancer sites...
Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African AmericansSangmi Kim
Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
Am J Epidemiol 171:969-79. 2010..05). Study results support the hypothesis that long-chain omega-3 PUFAs have beneficial effects in colorectal carcinogenesis. Whether or not the possible benefit of long-chain omega-3 PUFAs varies by race warrants further evaluation...
Association of intrauterine and early-life exposures with diagnosis of uterine leiomyomata by 35 years of age in the Sister StudyAimee A D'Aloisio
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 118:375-81. 2010..Early-life exposures to hormonally active compounds and other factors may affect later response to estrogen or progesterone and hence may influence development of uterine leiomyomata (fibroids)...
Epidemiology, public health, and the rhetoric of false positivesAaron Blair
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Environ Health Perspect 117:1809-13. 2009..Although we acknowledge that false positives do occur, we view the position of Boffetta and colleagues on false positives as unbalanced and potentially harmful to public health...
Questionnaire predictors of atopy in a US population sample: findings from the National Health and Nutrition Examination Survey, 2005-2006Jane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
Am J Epidemiol 173:544-52. 2011....
Pesticide exposure and hypertensive disorders during pregnancyTina M Saldana
Social and Scientific Systems, Inc, 1009 Slater Road, Durham, NC 27703, USA
Environ Health Perspect 117:1393-6. 2009..Hypertensive disorders of pregnancy, including pregnancy-induced hypertension (PIH) and preeclampsia (PE), complicate 2-8% of pregnancies. Few studies have examined environmental risk factors in relation to these conditions...
Pesticides and myocardial infarction incidence and mortality among male pesticide applicators in the Agricultural Health StudyKatherine T Mills
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 2233, USA
Am J Epidemiol 170:892-900. 2009..In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardial infarction mortality or nonfatal myocardial infarction associated with the occupational use of pesticides...
Obesity and weight gain in adulthood and telomere lengthSangmi Kim
Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, P O Box 12233, MD A3 05, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
Cancer Epidemiol Biomarkers Prev 18:816-20. 2009..33; 95% confidence interval, 1.30-1.36). These findings support the hypothesis that obesity may accelerate aging, and highlight the importance of maintaining a desirable weight in adulthood...
Telomere length, current perceived stress, and urinary stress hormones in womenChristine G Parks
Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27599, USA
Cancer Epidemiol Biomarkers Prev 18:551-60. 2009....
Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Int J Cancer 124:1206-12. 2009..The use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans...
Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health StudyDaehee Kang
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd EPS 8000, Rockville, MD 20852, USA
Environ Res 107:271-6. 2008..Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding...
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:80-7. 2008..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
Pesticide use and chronic bronchitis among farmers in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
Am J Ind Med 50:969-79. 2007..Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides...
Association of lead exposure with survival in amyotrophic lateral sclerosisFreya Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Environ Health Perspect 116:943-7. 2008..Reasons for the variability in survival among ALS cases are unknown but may include exposure to environmental neurotoxicants...
Head injury and amyotrophic lateral sclerosisHonglei Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Am J Epidemiol 166:810-6. 2007..7, 95 percent CI: 1.3, 2.2). In this study population, physical injuries to other body parts, including the trunk, arms, or legs, were not related to ALS risk. These data support the notion that head injury may increase the risk of ALS...
Using risk-based sampling to enrich cohorts for endpoints, genes, and exposuresClarice R Weinberg
Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Am J Epidemiol 166:447-55. 2007....
Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 70:9224-33. 2010..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
Maternal recall of breastfeeding duration by elderly womenJoanne H E Promislow
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Am J Epidemiol 161:289-96. 2005..The observed misclassification, if nondifferential with respect to outcome, would appreciably attenuate estimates of dose-response associations between breastfeeding duration and later health...
Chemical predictors of wheeze among farmer pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch and Biostatistics Branch, National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 165:683-9. 2002..5 (95% CI 1.2,1.9). Inclusion of crops and animals into these models did not significantly alter the observed OR. These associations, though small, suggest an independent role for specific pesticides in respiratory symptoms of farmers...
Pesticide use and pesticide-related symptoms among black farmers in the Agricultural Health StudyStephen A Martin
National Institute of Environmental Health Sciences, NIH, Epidemiology Branch, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 41:202-9. 2002..CONCLUSIONS: Differences between black and white farmers may be explained by farm characteristics or economics. Despite lower use of pesticides, black farmers may have other work practices that affect exposure and risk...
Lead exposure and amyotrophic lateral sclerosisFreya Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Epidemiology 13:311-9. 2002..Previous interview-based studies have suggested that exposure to neurotoxicants including metals might be related to ALS...
Pesticides and lung cancer risk in the agricultural health study cohortMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Am J Epidemiol 160:876-85. 2004..The usage levels in this cohort are considerably higher than those typically experienced by the general population. An excess risk among spouses directly exposed to pesticides could not be evaluated at this time...
DDT metabolite and androgens in African-American farmersStephen A Martin
National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3-05, Research Triangle Park, NC 27709, USA
Epidemiology 13:454-8. 2002..Plasma androgen levels decreased with age, a relation that has previously been studied only in whites. CONCLUSIONS: Studies of more highly exposed populations may be needed to evaluate effects, if any, of DDE...
Influence of medical conditions and lifestyle factors on the menstrual cycleAndrew S Rowland
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA
Epidemiology 13:668-74. 2002..Few studies have described medical and lifestyle factors associated with various menstrual cycle characteristics...
Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohortMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Am J Epidemiol 157:800-14. 2003..Important family history-pesticide interactions were observed...
Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
J Expo Anal Environ Epidemiol 12:313-8. 2002..While we are unable to validate directly the accuracy of a respondent's use of pesticides, this analysis suggests that participants provide plausible information regarding their pesticide use...
Associations between plasma DDE levels and immunologic measures in African-American farmers in North CarolinaGlinda S Cooper
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 112:1080-4. 2004..32-11.3; for > or = 12.0 microg/L compared with < 3.0 microg/L p,p'-DDE), but this difference was not statistically significant. These analyses provide evidence that p,p'-DDE modulates immune responses in humans...
Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmersJane A Hoppin
Epidemiology Branch and Biostatistics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 169:1308-13. 2004..89, 3.73), an indication of daily solvent exposure. These results add to the growing body of evidence of adverse respiratory effects of diesel exposure on the lung and suggest exposure to solvents may contribute as well...
Neurobehavioral performance and work experience in Florida farmworkersFreya Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1765-72. 2003..We conclude that long-term experience of farm work is associated with measurable deficits in cognitive and psychomotor function...
History of kidney stones as a possible risk factor for chronic kidney diseaseSuma Vupputuri
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Ann Epidemiol 14:222-8. 2004..The incidence of treated end-stage renal disease has increased progressively in the United States over the past several decades. It has been suggested that kidney stones may be a contributing factor for a small percentage of these patients...
Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health StudyMatthew R Bonner
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Environ Health Perspect 113:285-9. 2005..Although carbamate pesticides are suspected human carcinogens, these results should be interpreted cautiously because there was no a priori hypothesis specifically linking carbofuran to lung cancer...
Mortality among participants in the agricultural health studyAaron Blair
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Ann Epidemiol 15:279-85. 2005..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses...
VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS)Paul D Terry
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
J Neurogenet 18:429-34. 2004..7 - 13.4), consistent with the findings of the previous study. Given the wide confidence interval, our findings should be interpreted cautiously...
Neurologic symptoms in licensed private pesticide applicators in the agricultural health studyFreya Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Environ Health Perspect 113:877-82. 2005....
Lifestyle risk factors and chronic kidney diseaseSuma Vupputuri
Epidemiology Branch, National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
Ann Epidemiol 13:712-20. 2003..To examine the effects of lifestyle risk factors such as alcohol consumption, cigarette smoking and body mass index (BMI) on the development of chronic kidney disease...
Pesticides and atopic and nonatopic asthma among farm women in the Agricultural Health StudyJane A Hoppin
NIEHS Epidemiology Branch, MD A3 05, P O Box 12233, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 177:11-8. 2008..Risk factors for asthma among farm women are understudied...
Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genesFreya Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1335-9. 2003..These findings suggest that genetic susceptibility conferred by polymorphisms in ALAD may affect ALS risk, possibly through a mechanism related to internal lead exposure...
Phenolphthalein-containing laxative use in relation to adenomatous colorectal polyps in three studiesM P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 USA
Environ Health Perspect 105:1210-2. 1997..Although the low prevalence of frequent use made for relatively wide confidence intervals, overall these data suggest that use of phenolphthalein-containing laxatives does not increase risk of adenomatous colorectal polyps...
A model for predicting the frequency of high pesticide exposure events in the Agricultural Health StudyD T Mage
US Environmental Protection Agency, National Center for Environmental Assessment, Research Triangle Park, North Carolina 27711, USA
Environ Res 83:67-71. 2000..e., breaking hose) are the three factors responsible for the events observed. Special precautions for new or infrequent users of pesticides are indicated...
Dietary intake of calcium, magnesium and antioxidants in relation to risk of amyotrophic lateral sclerosisM P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle, NC 27709, USA
Neuroepidemiology 19:210-6. 2000..Overall, these dietary factors were not related to risk of ALS, though modestly protective associations were suggested for magnesium and lycopene...
Recruiting a community sample in collaboration with farmworkersF Kamel
National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
Environ Health Perspect 109:457-9. 2001..Collaboration with the community is essential to the success of such a project, and community characteristics can affect response rates...
Carbonated beverages and chronic kidney diseaseTina M Saldana
Epidemiology Branch, National Institute of Environmental Health Sciences NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
Epidemiology 18:501-6. 2007..Cola beverages, in particular, contain phosphoric acid and have been associated with urinary changes that promote kidney stones...
Workplace exposures and the risk of amyotrophic lateral sclerosisFang Fang
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
Environ Health Perspect 117:1387-92. 2009..Occupation has been suggested to play a role in amyotrophic lateral sclerosis (ALS) etiology, but detailed information on the importance of specific workplace exposures is lacking...
Prevalence of medication treatment for attention deficit-hyperactivity disorder among elementary school children in Johnston County, North CarolinaAndrew S Rowland
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
Am J Public Health 92:231-4. 2002..This study estimated the prevalence of medication treatment for attention deficit-hyperactivity disorder (ADHD) among elementary school children in a North Carolina county...
Occupation, hobbies, and acute leukemia in adultsPaul D Terry
Epidemiology Branch, National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
Leuk Res 29:1117-30. 2005..Differences were noted according to histological type. Other occupations and hobbies were not clearly associated with risk...
Studying the epidemiology of attention-deficit hyperactivity disorder: screening method and pilot resultsA S Rowland
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
Can J Psychiatry 46:931-40. 2001..The methods developed for this study and the pitfalls we encountered illustrate the challenges involved in conducting population-based studies of ADHD...
Childhood cancer mortality and radon concentration in drinking water in North CarolinaG W Collman
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
Br J Cancer 63:626-9. 1991..The strongest association was for the leukaemias, but risks were also suggested for other sites. These associations could be due to confounding or other biases, but the findings are consistent with other recent reports...
Risk of ovarian cancer in relation to use of phenolphthalein-containing laxativesG S Cooper
Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC 27709, USA
Br J Cancer 83:404-6. 2000..4 for any use of phenolphthalein-containing laxatives and OR 1.5 for 75 or more days of use)..
Fertility and exposure to solvents among families in the Agricultural Health StudyM Sallmen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Human Health Services, Research Triangle Park, North Carolina, USA
Occup Environ Med 63:469-75. 2006..Several studies have reported associations between solvent exposure and reduced female fertility, but the evidence is inconclusive for male fertility...
Multivitamin use and telomere length in womenQun Xu
Epidemiology Branch, National Institute for Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Am J Clin Nutr 89:1857-63. 2009..Telomere length may be a marker of biological aging. Multivitamin supplements represent a major source of micronutrients, which may affect telomere length by modulating oxidative stress and chronic inflammation...
Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defectH Chen
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Lancet 347:295-7. 1996..Both GST M1 (GSTM1) and GST theta 1 (GSTT1) genes have a "null" variant allele, in which the entire gene is absent. We tested whether the homozygous null genotype of GSTM1 and GSTT1 altered the risk for MDS...
Blood mercury level and blood pressure among US women: results from the National Health and Nutrition Examination Survey 1999-2000Suma Vupputuri
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
Environ Res 97:195-200. 2005..While an adverse effect of mercury exposure at background levels on BP was not present overall, an adverse association was present among non-fish-consuming young and middle-aged women...
Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health StudyKent W Thomas
National Exposure Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
J Expo Sci Environ Epidemiol 20:119-34. 2010..Results may also be of use in pesticide safety education for reducing exposures to pesticide applicators...
Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studiesDaniel Krewski
McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
Epidemiology 16:137-45. 2005..Residential exposure to radon is at much lower levels, and the risk of lung cancer with residential exposure is less clear. We conducted a systematic analysis of pooled data from all North American residential radon studies...
Patterns of pesticide use and their determinants among wives of farmer pesticide applicators in the Agricultural Health StudyEllen F Kirrane
Coda Inc, Durham, North Carolina, USA
J Occup Environ Med 46:856-65. 2004..Farm women reporting the heaviest pesticide use could exacerbate their exposure by engaging in practices that could increase pesticide contact...
Validating cancer histories in deceased relativesGarth H Rauscher
Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, IL 60612, USA
Epidemiology 16:262-5. 2005..A family history of cancer is a marker of familially shared genetic and environmental risk factors for cancer but is subject to inaccurate and biased reporting...
Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
Environ Health Perspect 115:528-34. 2007..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited...
An overview of the North American residential radon and lung cancer case-control studiesR William Field
Department of Occupational and Environmental Health, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
J Toxicol Environ Health A 69:599-631. 2006..Eleven WLM(5-19) is approximately equivalent to an average residential radon exposure of 4 pCi/L for 15 yr, assuming a 70% home occupancy...
A combined analysis of North American case-control studies of residential radon and lung cancerDaniel Krewski
Department of Epidemiology and Community Medicine, Faculty of Medicine, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
J Toxicol Environ Health A 69:533-97. 2006..Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners...
Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health studyEllen F Kirrane
CODA, Inc, Durham, NC 27709, USA
Am J Epidemiol 161:1020-9. 2005..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation...
Is family history of breast cancer a marker of susceptibility to exposures in the incidence of de novo adult acute leukemia?Garth H Rauscher
Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, Illinois 60612, USA
Cancer Epidemiol Biomarkers Prev 12:289-94. 2003..Family history of breast cancer might be a marker of susceptibility to a range of leukemia risk factors, whose effects are generally weak or nonexistent when considered alone...
Pesticide exposure and timing of menopause: the Agricultural Health StudySherry L Farr
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Epidemiol 163:731-42. 2006..78, 0.97) and by approximately 5 months for women who used hormonally active pesticides (hazard ratio = 0.77, 95% confidence interval: 0.65, 0.92). Pesticide use may be associated with a later age at menopause...
Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health StudyAnneclaire J De Roos
Program in Epidemiology, Fred Hutchinson Cancer Research Center and the Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA
Environ Health Perspect 113:49-54. 2005..Given the widespread use of glyphosate, future analyses of the AHS will allow further examination of long-term health effects, including less common cancers...
Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
J Natl Cancer Inst 96:1781-9. 2004..18 (95% confidence interval = 1.31 to 3.64) times that of those with no chlorpyrifos exposure. CONCLUSION: Our findings suggest an association between chlorpyrifos use and incidence of lung cancer that deserves further evaluation...
Pesticide use and colorectal cancer risk in the Agricultural Health StudyWon Jin Lee
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
Int J Cancer 121:339-46. 2007..Nonetheless the possibility of an association between exposure to certain pesticides and incidence of colorectal cancer among pesticide applicators deserves further evaluation...
Rheumatoid arthritis among women in the Agricultural Health Study: risk associated with farming activities and exposuresAnneclaire J De Roos
University of Washington Department of Epidemiology and Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Ann Epidemiol 15:762-70. 2005..We studied risk factors for RA in the Agricultural Health Study, a cohort of over 57,000 licensed pesticide applicators and their spouses...
A quantitative approach for estimating exposure to pesticides in the Agricultural Health StudyMustafa Dosemeci
National Cancer Institute, NIH, Bethesda, MD, USA
Ann Occup Hyg 46:245-60. 2002....
Alcohol intake and incidence of de novo adult acute leukemiaGarth H Rauscher
School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, 816 SPHPI M C 923, 1603 W Taylor, Chicago, IL 60612, USA
Leuk Res 28:1263-5. 2004..1; 95% CI: 1.2, 3.8). Divergent results might reflect the effect of different nutrients in beer and wine, unmeasured confounding, or differing impacts of selection bias on these associations...
Maternal age, exposure to siblings, and risk of amyotrophic lateral sclerosisFang Fang
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Am J Epidemiol 167:1281-6. 2008..Although the strength of the observed associations was modest, these results provided further support for the theory that early life exposures might contribute to the disease pathogenesis...
Personal and family medical history correlates of rheumatoid arthritisAnneclaire J De Roos
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and Department of Epidemiology, University of Washington, Seattle, WA 98109, USA
Ann Epidemiol 18:433-9. 2008..We studied personal and family medical history correlates of incident and prevalent RA in women...
Cancer risk and parental pesticide application in children of Agricultural Health Study participantsKori B Flower
Robert Wood Johnson Clinical Scholars Program and Division of Community Pediatrics, Department of Pediatrics, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7105, USA
Environ Health Perspect 112:631-5. 2004..Identification of excess lymphoma risk suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma...
