D P Sandler

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Indoor radon and lung cancer risk in connecticut and utah
    Dale P Sandler
    Epidemiology Branch, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Toxicol Environ Health A 69:633-54. 2006
  2. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
  3. pmc Fonofos exposure and cancer incidence in the agricultural health study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Environ Health Perspect 114:1838-42. 2006
  4. pmc Association between blood lead and the risk of amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Am J Epidemiol 171:1126-33. 2010
  5. ncbi request reprint Malathion exposure and the incidence of cancer in the agricultural health study
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 166:1023-34. 2007
  6. ncbi request reprint Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon
    Laura E Beane Freeman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Am J Epidemiol 162:1070-9. 2005
  7. ncbi request reprint Carbaryl exposure and incident cancer in the Agricultural Health Study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 121:1799-805. 2007
  8. ncbi request reprint Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Am J Epidemiol 159:373-80. 2004
  9. pmc Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort study
    Martha P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 53:486-96. 2010
  10. ncbi request reprint Retinal degeneration in licensed pesticide applicators
    F Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Ind Med 37:618-28. 2000

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Indoor radon and lung cancer risk in connecticut and utah
    Dale P Sandler
    Epidemiology Branch, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Toxicol Environ Health A 69:633-54. 2006
    ..While results were consistent with the estimates from studies of miners, this study provides no evidence of an increased risk for lung cancer at the exposure levels observed...
  2. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
    ....
  3. pmc Fonofos exposure and cancer incidence in the agricultural health study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Environ Health Perspect 114:1838-42. 2006
    ..A previous investigation in this cohort linked exposure to the organophosphate fonofos with incident prostate cancer in subjects with family history of prostate cancer...
  4. pmc Association between blood lead and the risk of amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Am J Epidemiol 171:1126-33. 2010
    ..32). These results extend earlier findings by accounting for bone turnover in confirming the association between elevated blood lead level and higher risk of ALS...
  5. ncbi request reprint Malathion exposure and the incidence of cancer in the agricultural health study
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 166:1023-34. 2007
    ..Although the rate ratios for melanoma were reduced, small numbers and lack of experimental evidence suggest that the observed reductions may have arisen by chance...
  6. ncbi request reprint Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon
    Laura E Beane Freeman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Am J Epidemiol 162:1070-9. 2005
    ..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans...
  7. ncbi request reprint Carbaryl exposure and incident cancer in the Agricultural Health Study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 121:1799-805. 2007
    ..No associations were observed with other examined cancer sites. Because the observed results were not hypothesized a priori and because of limited study of their biological plausibility, they should be interpreted with caution...
  8. ncbi request reprint Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Am J Epidemiol 159:373-80. 2004
    ..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study...
  9. pmc Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort study
    Martha P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 53:486-96. 2010
    ..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study...
  10. ncbi request reprint Retinal degeneration in licensed pesticide applicators
    F Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Ind Med 37:618-28. 2000
    ..Retinal degeneration is the leading cause of visual impairment in older adults, but little is known about its relationship to neurotoxic exposures...
  11. ncbi request reprint Exposure opportunities of families of farmer pesticide applicators
    B C Gladen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 34:581-7. 1998
    ..Families of farmer pesticide applicators have unusual opportunities for exposure, directly or indirectly, to pesticides. These exposures are not well characterized...
  12. pmc Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study
    J A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3 05, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
    Eur Respir J 34:1296-303. 2009
    ..There was little evidence that allergy alone was driving these associations. In conclusion, pesticides may be an overlooked contributor to asthma risk among farmers...
  13. ncbi request reprint Association of cigarette smoking with amyotrophic lateral sclerosis
    F Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neuroepidemiology 18:194-202. 1999
    ..The association of cigarette smoking with ALS was not affected by adjusting for alcohol use. In contrast, the weak relationship of ALS with alcohol use was apparently due to confounding by smoking...
  14. pmc Chronic bronchitis among nonsmoking farm women in the agricultural health study
    Martin Valcin
    Epidemiology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
    J Occup Environ Med 49:574-83. 2007
    ..The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women...
  15. ncbi request reprint Pesticide use and breast cancer risk among farmers' wives in the agricultural health study
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Epidemiol 161:121-35. 2005
    ..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk...
  16. ncbi request reprint Reduced fertility among overweight and obese men
    Markku Sallmen
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Epidemiology 17:520-3. 2006
    ..Overweight and obese men have been reported to have lower sperm counts and hormonal changes, but data are lacking regarding effects on couple fertility...
  17. pmc Pendimethalin exposure and cancer incidence among pesticide applicators
    Lifang Hou
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Epidemiology 17:302-7. 2006
    ..We evaluated the incidence of cancer in relation to reported pendimethelin use among pesticide applicators in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina...
  18. ncbi request reprint Characteristics of pesticide use in a pesticide applicator cohort: the Agricultural Health Study
    M C Alavanja
    Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, Maryland, 20892
    Environ Res 80:172-9. 1999
    ..This heterogeneity in potential exposures to pesticides between states should be useful for subsequent epidemiologic analyses using internal comparison groups...
  19. ncbi request reprint Menstrual patterns and risk of adult-onset diabetes mellitus
    G S Cooper
    Epidemiology Branch A3 05, National Institute of Environmental Health Sciences, PO Box 12233, Research Triangle Park, Durham, NC 27709, USA
    J Clin Epidemiol 53:1170-3. 2000
    ..These results do not support the association of long or irregular menstrual cycles with post-menopausal diabetes incidence, but do suggest a possible association of longer bleeding duration with subsequent onset of diabetes...
  20. ncbi request reprint Neurologic symptoms in licensed pesticide applicators in the Agricultural Health Study
    F Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
    Hum Exp Toxicol 26:243-50. 2007
    ..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning...
  21. pmc Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003
    M P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 167:1235-46. 2008
    ..Long-term exposure from handling certain pesticides, in particular, organochlorine and organophosphate insecticides, may be associated with increased risk of diabetes...
  22. pmc Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smoking
    J A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Occup Environ Med 60:e3. 2003
    ..Exposure to animals, their feeds, and by-products contribute to respiratory symptoms among farmers...
  23. ncbi request reprint Lead exposure as a risk factor for amyotrophic lateral sclerosis
    F Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Neurodegener Dis 2:195-201. 2005
    ..Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2- to >4-fold. However, these results may have been affected by recall bias...
  24. pmc Employment and work schedule are related to telomere length in women
    C G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Insititues of Health, Research Triangle Park, NC 27599, USA
    Occup Environ Med 68:582-9. 2011
    ....
  25. ncbi request reprint Cancer incidence in the agricultural health study
    Michael C R Alavanja
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Scand J Work Environ Health 31:39-45; discussion 5-7. 2005
    ..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture...
  26. ncbi request reprint Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health Study
    Tina M Saldana
    Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
    Diabetes Care 30:529-34. 2007
    ..To examine the association between pesticide use during pregnancy and gestational diabetes mellitus (GDM) among wives of licensed pesticide applicators...
  27. pmc Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709 2233, USA
    Occup Environ Med 64:334-41. 2007
    ..Farmer's lung, or hypersensitivity pneumonitis, is an important contributor to respiratory morbidity among farmers...
  28. ncbi request reprint Pesticides and adult respiratory outcomes in the agricultural health study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Healh Science, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
    Ann N Y Acad Sci 1076:343-54. 2006
    ..00-2.19) for farmers and 1.96 (95% CI = 1.05-3.66) for commercial applicators. Our wheeze results are consistent with recent animal models that support a role for organophosphates and respiratory outcomes...
  29. pmc Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health study
    Claudine Samanic
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Environ Health Perspect 114:1521-6. 2006
    ..We evaluated cancer incidence among pesticide applicators exposed to dicamba in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in North Carolina and Iowa...
  30. ncbi request reprint Pesticides associated with wheeze among commercial pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Epidemiol 163:1129-37. 2006
    ..40, 95% CI: 1.24, 4.65). These results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl...
  31. ncbi request reprint Cigarette smoking and cancer risk: modeling total exposure and intensity
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 166:479-89. 2007
    ..The intensity effects were statistically homogeneous, indicating that after accounting for risk from total pack-years, intensity patterns were comparable across the diverse cancer sites...
  32. pmc Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans
    Sangmi Kim
    Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 171:969-79. 2010
    ..05). Study results support the hypothesis that long-chain omega-3 PUFAs have beneficial effects in colorectal carcinogenesis. Whether or not the possible benefit of long-chain omega-3 PUFAs varies by race warrants further evaluation...
  33. pmc Association of intrauterine and early-life exposures with diagnosis of uterine leiomyomata by 35 years of age in the Sister Study
    Aimee A D'Aloisio
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 118:375-81. 2010
    ..Early-life exposures to hormonally active compounds and other factors may affect later response to estrogen or progesterone and hence may influence development of uterine leiomyomata (fibroids)...
  34. pmc Epidemiology, public health, and the rhetoric of false positives
    Aaron Blair
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Environ Health Perspect 117:1809-13. 2009
    ..Although we acknowledge that false positives do occur, we view the position of Boffetta and colleagues on false positives as unbalanced and potentially harmful to public health...
  35. pmc Questionnaire predictors of atopy in a US population sample: findings from the National Health and Nutrition Examination Survey, 2005-2006
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
    Am J Epidemiol 173:544-52. 2011
    ....
  36. pmc Pesticide exposure and hypertensive disorders during pregnancy
    Tina M Saldana
    Social and Scientific Systems, Inc, 1009 Slater Road, Durham, NC 27703, USA
    Environ Health Perspect 117:1393-6. 2009
    ..Hypertensive disorders of pregnancy, including pregnancy-induced hypertension (PIH) and preeclampsia (PE), complicate 2-8% of pregnancies. Few studies have examined environmental risk factors in relation to these conditions...
  37. pmc Pesticides and myocardial infarction incidence and mortality among male pesticide applicators in the Agricultural Health Study
    Katherine T Mills
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 2233, USA
    Am J Epidemiol 170:892-900. 2009
    ..In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardial infarction mortality or nonfatal myocardial infarction associated with the occupational use of pesticides...
  38. pmc Obesity and weight gain in adulthood and telomere length
    Sangmi Kim
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, P O Box 12233, MD A3 05, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    Cancer Epidemiol Biomarkers Prev 18:816-20. 2009
    ..33; 95% confidence interval, 1.30-1.36). These findings support the hypothesis that obesity may accelerate aging, and highlight the importance of maintaining a desirable weight in adulthood...
  39. pmc Telomere length, current perceived stress, and urinary stress hormones in women
    Christine G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27599, USA
    Cancer Epidemiol Biomarkers Prev 18:551-60. 2009
    ....
  40. pmc Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 124:1206-12. 2009
    ..The use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans...
  41. doi request reprint Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study
    Daehee Kang
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd EPS 8000, Rockville, MD 20852, USA
    Environ Res 107:271-6. 2008
    ..Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding...
  42. pmc Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 17:80-7. 2008
    ..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
  43. pmc Pesticide use and chronic bronchitis among farmers in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
    Am J Ind Med 50:969-79. 2007
    ..Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides...
  44. pmc Association of lead exposure with survival in amyotrophic lateral sclerosis
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 116:943-7. 2008
    ..Reasons for the variability in survival among ALS cases are unknown but may include exposure to environmental neurotoxicants...
  45. pmc Head injury and amyotrophic lateral sclerosis
    Honglei Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 166:810-6. 2007
    ..7, 95 percent CI: 1.3, 2.2). In this study population, physical injuries to other body parts, including the trunk, arms, or legs, were not related to ALS risk. These data support the notion that head injury may increase the risk of ALS...
  46. pmc Using risk-based sampling to enrich cohorts for endpoints, genes, and exposures
    Clarice R Weinberg
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 166:447-55. 2007
    ....
  47. pmc Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 70:9224-33. 2010
    ..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
  48. ncbi request reprint Maternal recall of breastfeeding duration by elderly women
    Joanne H E Promislow
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 161:289-96. 2005
    ..The observed misclassification, if nondifferential with respect to outcome, would appreciably attenuate estimates of dose-response associations between breastfeeding duration and later health...
  49. ncbi request reprint Chemical predictors of wheeze among farmer pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch and Biostatistics Branch, National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 165:683-9. 2002
    ..5 (95% CI 1.2,1.9). Inclusion of crops and animals into these models did not significantly alter the observed OR. These associations, though small, suggest an independent role for specific pesticides in respiratory symptoms of farmers...
  50. ncbi request reprint Pesticide use and pesticide-related symptoms among black farmers in the Agricultural Health Study
    Stephen A Martin
    National Institute of Environmental Health Sciences, NIH, Epidemiology Branch, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 41:202-9. 2002
    ..Health effects of pesticides have not been well studied in black farmers. We describe agricultural practices and pesticide-related symptoms in North Carolina black and white farmers participating in the Agricultural Health Study...
  51. ncbi request reprint Lead exposure and amyotrophic lateral sclerosis
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Epidemiology 13:311-9. 2002
    ..Previous interview-based studies have suggested that exposure to neurotoxicants including metals might be related to ALS...
  52. ncbi request reprint Pesticides and lung cancer risk in the agricultural health study cohort
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 160:876-85. 2004
    ..The usage levels in this cohort are considerably higher than those typically experienced by the general population. An excess risk among spouses directly exposed to pesticides could not be evaluated at this time...
  53. ncbi request reprint DDT metabolite and androgens in African-American farmers
    Stephen A Martin
    National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3 05, Research Triangle Park, NC 27709, USA
    Epidemiology 13:454-8. 2002
    ..The ubiquitous dichlorodiphenyltrichloroethane (DDT) metabolite 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) is an androgen receptor antagonist. Data on potential antiandrogenic activity of DDE in humans are limited...
  54. ncbi request reprint Influence of medical conditions and lifestyle factors on the menstrual cycle
    Andrew S Rowland
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA
    Epidemiology 13:668-74. 2002
    ..Few studies have described medical and lifestyle factors associated with various menstrual cycle characteristics...
  55. ncbi request reprint Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 157:800-14. 2003
    ..Important family history-pesticide interactions were observed...
  56. ncbi request reprint Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
    J Expo Anal Environ Epidemiol 12:313-8. 2002
    ..While we are unable to validate directly the accuracy of a respondent's use of pesticides, this analysis suggests that participants provide plausible information regarding their pesticide use...
  57. pmc Associations between plasma DDE levels and immunologic measures in African-American farmers in North Carolina
    Glinda S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 112:1080-4. 2004
    ..32-11.3; for > or = 12.0 microg/L compared with < 3.0 microg/L p,p'-DDE), but this difference was not statistically significant. These analyses provide evidence that p,p'-DDE modulates immune responses in humans...
  58. ncbi request reprint Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmers
    Jane A Hoppin
    Epidemiology Branch and Biostatistics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 169:1308-13. 2004
    ..89, 3.73), an indication of daily solvent exposure. These results add to the growing body of evidence of adverse respiratory effects of diesel exposure on the lung and suggest exposure to solvents may contribute as well...
  59. pmc Neurobehavioral performance and work experience in Florida farmworkers
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1765-72. 2003
    ..We conclude that long-term experience of farm work is associated with measurable deficits in cognitive and psychomotor function...
  60. ncbi request reprint History of kidney stones as a possible risk factor for chronic kidney disease
    Suma Vupputuri
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Ann Epidemiol 14:222-8. 2004
    ..The incidence of treated end-stage renal disease has increased progressively in the United States over the past several decades. It has been suggested that kidney stones may be a contributing factor for a small percentage of these patients...
  61. pmc Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health Study
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 113:285-9. 2005
    ..Although carbamate pesticides are suspected human carcinogens, these results should be interpreted cautiously because there was no a priori hypothesis specifically linking carbofuran to lung cancer...
  62. ncbi request reprint Mortality among participants in the agricultural health study
    Aaron Blair
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Ann Epidemiol 15:279-85. 2005
    ..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses...
  63. ncbi request reprint VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS)
    Paul D Terry
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
    J Neurogenet 18:429-34. 2004
    ..7 - 13.4), consistent with the findings of the previous study. Given the wide confidence interval, our findings should be interpreted cautiously...
  64. pmc Neurologic symptoms in licensed private pesticide applicators in the agricultural health study
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 113:877-82. 2005
    ....
  65. ncbi request reprint Lifestyle risk factors and chronic kidney disease
    Suma Vupputuri
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
    Ann Epidemiol 13:712-20. 2003
    ..To examine the effects of lifestyle risk factors such as alcohol consumption, cigarette smoking and body mass index (BMI) on the development of chronic kidney disease...
  66. pmc Pesticides and atopic and nonatopic asthma among farm women in the Agricultural Health Study
    Jane A Hoppin
    NIEHS Epidemiology Branch, MD A3 05, P O Box 12233, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 177:11-8. 2008
    ..Risk factors for asthma among farm women are understudied...
  67. pmc Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1335-9. 2003
    ..These findings suggest that genetic susceptibility conferred by polymorphisms in ALAD may affect ALS risk, possibly through a mechanism related to internal lead exposure...
  68. pmc Phenolphthalein-containing laxative use in relation to adenomatous colorectal polyps in three studies
    M P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 USA
    Environ Health Perspect 105:1210-2. 1997
    ..Although the low prevalence of frequent use made for relatively wide confidence intervals, overall these data suggest that use of phenolphthalein-containing laxatives does not increase risk of adenomatous colorectal polyps...
  69. ncbi request reprint A model for predicting the frequency of high pesticide exposure events in the Agricultural Health Study
    D T Mage
    US Environmental Protection Agency, National Center for Environmental Assessment, Research Triangle Park, North Carolina 27711, USA
    Environ Res 83:67-71. 2000
    ..e., breaking hose) are the three factors responsible for the events observed. Special precautions for new or infrequent users of pesticides are indicated...
  70. ncbi request reprint Dietary intake of calcium, magnesium and antioxidants in relation to risk of amyotrophic lateral sclerosis
    M P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle, NC 27709, USA
    Neuroepidemiology 19:210-6. 2000
    ..Overall, these dietary factors were not related to risk of ALS, though modestly protective associations were suggested for magnesium and lycopene...
  71. pmc Recruiting a community sample in collaboration with farmworkers
    F Kamel
    National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 109:457-9. 2001
    ..Collaboration with the community is essential to the success of such a project, and community characteristics can affect response rates...
  72. pmc Carbonated beverages and chronic kidney disease
    Tina M Saldana
    Epidemiology Branch, National Institute of Environmental Health Sciences NIEHS, NIH, DHHS, Research Triangle Park, NC 27709, USA
    Epidemiology 18:501-6. 2007
    ..Cola beverages, in particular, contain phosphoric acid and have been associated with urinary changes that promote kidney stones...
  73. pmc Workplace exposures and the risk of amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 117:1387-92. 2009
    ..Occupation has been suggested to play a role in amyotrophic lateral sclerosis (ALS) etiology, but detailed information on the importance of specific workplace exposures is lacking...
  74. pmc Prevalence of medication treatment for attention deficit-hyperactivity disorder among elementary school children in Johnston County, North Carolina
    Andrew S Rowland
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
    Am J Public Health 92:231-4. 2002
    ..This study estimated the prevalence of medication treatment for attention deficit-hyperactivity disorder (ADHD) among elementary school children in a North Carolina county...
  75. ncbi request reprint Occupation, hobbies, and acute leukemia in adults
    Paul D Terry
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
    Leuk Res 29:1117-30. 2005
    ..Differences were noted according to histological type. Other occupations and hobbies were not clearly associated with risk...
  76. ncbi request reprint Studying the epidemiology of attention-deficit hyperactivity disorder: screening method and pilot results
    A S Rowland
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Can J Psychiatry 46:931-40. 2001
    ..The methods developed for this study and the pitfalls we encountered illustrate the challenges involved in conducting population-based studies of ADHD...
  77. pmc Childhood cancer mortality and radon concentration in drinking water in North Carolina
    G W Collman
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Br J Cancer 63:626-9. 1991
    ..The strongest association was for the leukaemias, but risks were also suggested for other sites. These associations could be due to confounding or other biases, but the findings are consistent with other recent reports...
  78. pmc Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
    G S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC 27709, USA
    Br J Cancer 83:404-6. 2000
    ..4 for any use of phenolphthalein-containing laxatives and OR 1.5 for 75 or more days of use)..
  79. pmc Fertility and exposure to solvents among families in the Agricultural Health Study
    M Sallmen
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Human Health Services, Research Triangle Park, North Carolina, USA
    Occup Environ Med 63:469-75. 2006
    ..Several studies have reported associations between solvent exposure and reduced female fertility, but the evidence is inconclusive for male fertility...
  80. pmc Multivitamin use and telomere length in women
    Qun Xu
    Epidemiology Branch, National Institute for Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Am J Clin Nutr 89:1857-63. 2009
    ..Telomere length may be a marker of biological aging. Multivitamin supplements represent a major source of micronutrients, which may affect telomere length by modulating oxidative stress and chronic inflammation...
  81. ncbi request reprint Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect
    H Chen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Lancet 347:295-7. 1996
    ..Both GST M1 (GSTM1) and GST theta 1 (GSTT1) genes have a "null" variant allele, in which the entire gene is absent. We tested whether the homozygous null genotype of GSTM1 and GSTT1 altered the risk for MDS...
  82. ncbi request reprint Blood mercury level and blood pressure among US women: results from the National Health and Nutrition Examination Survey 1999-2000
    Suma Vupputuri
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
    Environ Res 97:195-200. 2005
    ..While an adverse effect of mercury exposure at background levels on BP was not present overall, an adverse association was present among non-fish-consuming young and middle-aged women...
  83. pmc Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study
    Kent W Thomas
    National Exposure Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 20:119-34. 2010
    ..Results may also be of use in pesticide safety education for reducing exposures to pesticide applicators...
  84. ncbi request reprint Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Epidemiology 16:137-45. 2005
    ..Residential exposure to radon is at much lower levels, and the risk of lung cancer with residential exposure is less clear. We conducted a systematic analysis of pooled data from all North American residential radon studies...
  85. ncbi request reprint Patterns of pesticide use and their determinants among wives of farmer pesticide applicators in the Agricultural Health Study
    Ellen F Kirrane
    Coda Inc, Durham, North Carolina, USA
    J Occup Environ Med 46:856-65. 2004
    ..Farm women reporting the heaviest pesticide use could exacerbate their exposure by engaging in practices that could increase pesticide contact...
  86. ncbi request reprint Validating cancer histories in deceased relatives
    Garth H Rauscher
    Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, IL 60612, USA
    Epidemiology 16:262-5. 2005
    ..A family history of cancer is a marker of familially shared genetic and environmental risk factors for cancer but is subject to inaccurate and biased reporting...
  87. pmc Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
    Environ Health Perspect 115:528-34. 2007
    ..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited...
  88. ncbi request reprint An overview of the North American residential radon and lung cancer case-control studies
    R William Field
    Department of Occupational and Environmental Health, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    J Toxicol Environ Health A 69:599-631. 2006
    ..Eleven WLM(5-19) is approximately equivalent to an average residential radon exposure of 4 pCi/L for 15 yr, assuming a 70% home occupancy...
  89. ncbi request reprint A combined analysis of North American case-control studies of residential radon and lung cancer
    Daniel Krewski
    Department of Epidemiology and Community Medicine, Faculty of Medicine, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 69:533-97. 2006
    ..Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners...
  90. ncbi request reprint Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study
    Ellen F Kirrane
    CODA, Inc, Durham, NC 27709, USA
    Am J Epidemiol 161:1020-9. 2005
    ..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation...
  91. ncbi request reprint Is family history of breast cancer a marker of susceptibility to exposures in the incidence of de novo adult acute leukemia?
    Garth H Rauscher
    Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Cancer Epidemiol Biomarkers Prev 12:289-94. 2003
    ..Family history of breast cancer might be a marker of susceptibility to a range of leukemia risk factors, whose effects are generally weak or nonexistent when considered alone...
  92. ncbi request reprint Pesticide exposure and timing of menopause: the Agricultural Health Study
    Sherry L Farr
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Am J Epidemiol 163:731-42. 2006
    ..78, 0.97) and by approximately 5 months for women who used hormonally active pesticides (hazard ratio = 0.77, 95% confidence interval: 0.65, 0.92). Pesticide use may be associated with a later age at menopause...
  93. pmc Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health Study
    Anneclaire J De Roos
    Program in Epidemiology, Fred Hutchinson Cancer Research Center and the Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA
    Environ Health Perspect 113:49-54. 2005
    ..Given the widespread use of glyphosate, future analyses of the AHS will allow further examination of long-term health effects, including less common cancers...
  94. ncbi request reprint Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    J Natl Cancer Inst 96:1781-9. 2004
    ..We evaluated the incidence of cancer among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina...
  95. pmc Pesticide use and colorectal cancer risk in the Agricultural Health Study
    Won Jin Lee
    Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
    Int J Cancer 121:339-46. 2007
    ..Nonetheless the possibility of an association between exposure to certain pesticides and incidence of colorectal cancer among pesticide applicators deserves further evaluation...
  96. ncbi request reprint Rheumatoid arthritis among women in the Agricultural Health Study: risk associated with farming activities and exposures
    Anneclaire J De Roos
    University of Washington Department of Epidemiology and Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Ann Epidemiol 15:762-70. 2005
    ..We studied risk factors for RA in the Agricultural Health Study, a cohort of over 57,000 licensed pesticide applicators and their spouses...
  97. ncbi request reprint A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study
    Mustafa Dosemeci
    National Cancer Institute, NIH, Bethesda, MD, USA
    Ann Occup Hyg 46:245-60. 2002
    ....
  98. ncbi request reprint Alcohol intake and incidence of de novo adult acute leukemia
    Garth H Rauscher
    School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, 816 SPHPI M C 923, 1603 W Taylor, Chicago, IL 60612, USA
    Leuk Res 28:1263-5. 2004
    ..1; 95% CI: 1.2, 3.8). Divergent results might reflect the effect of different nutrients in beer and wine, unmeasured confounding, or differing impacts of selection bias on these associations...
  99. pmc Maternal age, exposure to siblings, and risk of amyotrophic lateral sclerosis
    Fang Fang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 167:1281-6. 2008
    ..Although the strength of the observed associations was modest, these results provided further support for the theory that early life exposures might contribute to the disease pathogenesis...
  100. pmc Personal and family medical history correlates of rheumatoid arthritis
    Anneclaire J De Roos
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and Department of Epidemiology, University of Washington, Seattle, WA 98109, USA
    Ann Epidemiol 18:433-9. 2008
    ..We studied personal and family medical history correlates of incident and prevalent RA in women...
  101. pmc Cancer risk and parental pesticide application in children of Agricultural Health Study participants
    Kori B Flower
    Robert Wood Johnson Clinical Scholars Program and Division of Community Pediatrics, Department of Pediatrics, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7105, USA
    Environ Health Perspect 112:631-5. 2004
    ..Identification of excess lymphoma risk suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma...