Research Topics
| Vichetra SamSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
ROC and confusion analysis of structure comparison methods identify the main causes of divergence from manual protein classificationVichetra Sam
Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA
BMC Bioinformatics 7:206. 2006..Previous attempts to use computerized structure comparison methods show only partial agreement with curated databases, but have failed to provide detailed statistical and structural analysis of the causes of these divergences...
Towards an automatic classification of protein structural domains based on structural similarityVichetra Sam
Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA
BMC Bioinformatics 9:74. 2008..Another possibility is the difference between manual and automatic classification procedures. We explore the degree to which these two factors might affect the final classification...
DOMIRE: a web server for identifying structural domains and their neighbors in proteinsFranck Samson
Institut National de la Recherche Agronomique, UR1077, Unité Mathématique, Informatique et Génome, 78350 Jouy en Josas, France
Bioinformatics 28:1040-1. 2012..DOMIRE, by displaying the protein structural domain organization, can be a useful tool for defining protein common cores and for unravelling the evolutionary relationship between different proteins...
Protein domain assignment from the recurrence of locally similar structuresChin Hsien Tai
Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Proteins 79:853-66. 2011..In addition, it indicates that domains are indeed made of recurrent small structural pieces that are used to build protein structures of many different folds as suggested by recent studies...
