Kristina I Rother

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes
    Gayatri Sarkar
    Corresponding author Kristina I Rother
    Diabetes Care 37:666-70. 2014
  2. pmc Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes
    Kristina I Rother
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 32:2251-7. 2009
  3. pmc Obstructive sleep apnea is a predictor of abnormal glucose metabolism in chronically sleep deprived obese adults
    Giovanni Cizza
    Section on Neuroendocrinology of Obesity, National Institute of Diabetes, Digestive, and Kidney Disease, Bethesda, Maryland, USA
    PLoS ONE 8:e65400. 2013
  4. pmc Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy
    Scott A Soleimanpour
    Islet and Autoimmunity Branch, NIDDK, NIH, Bethesda, MD, USA
    Cell Transplant 21:1297-304. 2012
  5. ncbi request reprint Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience
    Boaz Hirshberg
    Transplantation and Autoimmunity Branch, National Institutes of Health Department of Health and Human Services, Bethesda, Maryland, USA
    Diabetes Care 26:3288-95. 2003
  6. doi request reprint Neck circumference is a predictor of metabolic syndrome and obstructive sleep apnea in short-sleeping obese men and women
    Giovanni Cizza
    1 Section on Neuroendocrinology of Obesity, Diabetes, Endocrinology, and Obesity Branch National Institute of Diabetes and Digestive and Kidney Diseases DEOB NIDDK, Bethesda, Maryland
    Metab Syndr Relat Disord 12:231-41. 2014
  7. pmc Effects of diet soda on gut hormones in youths with diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 35:959-64. 2012
  8. pmc Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes Technol Ther 13:457-60. 2011
  9. pmc Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    Kristina I Rother
    Islet and Autoimmunity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 114:877-83. 2004
  10. pmc Interacting epidemics? Sleep curtailment, insulin resistance, and obesity
    Eliane A Lucassen
    Immunogenetics Section, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1264:110-34. 2012

Collaborators

Detail Information

Publications29

  1. doi request reprint Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes
    Gayatri Sarkar
    Corresponding author Kristina I Rother
    Diabetes Care 37:666-70. 2014
    ..We studied the effects of exenatide on glucose homeostasis in adults with long-standing type 1 diabetes...
  2. pmc Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes
    Kristina I Rother
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 32:2251-7. 2009
    ....
  3. pmc Obstructive sleep apnea is a predictor of abnormal glucose metabolism in chronically sleep deprived obese adults
    Giovanni Cizza
    Section on Neuroendocrinology of Obesity, National Institute of Diabetes, Digestive, and Kidney Disease, Bethesda, Maryland, USA
    PLoS ONE 8:e65400. 2013
    ..Sleep abnormalities, including obstructive sleep apnea (OSA), have been associated with insulin resistance...
  4. pmc Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy
    Scott A Soleimanpour
    Islet and Autoimmunity Branch, NIDDK, NIH, Bethesda, MD, USA
    Cell Transplant 21:1297-304. 2012
    ..Furthermore, improved glycemic control achieved via islet transplantation over the diabetic state might be attained, in part, via reduced glucagon secretion...
  5. ncbi request reprint Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience
    Boaz Hirshberg
    Transplantation and Autoimmunity Branch, National Institutes of Health Department of Health and Human Services, Bethesda, Maryland, USA
    Diabetes Care 26:3288-95. 2003
    ..The aim of this study was to describe the National Institutes of Health's experience initiating an islet isolation and transplantation center, including descriptions of our first six recipients, and lessons learned...
  6. doi request reprint Neck circumference is a predictor of metabolic syndrome and obstructive sleep apnea in short-sleeping obese men and women
    Giovanni Cizza
    1 Section on Neuroendocrinology of Obesity, Diabetes, Endocrinology, and Obesity Branch National Institute of Diabetes and Digestive and Kidney Diseases DEOB NIDDK, Bethesda, Maryland
    Metab Syndr Relat Disord 12:231-41. 2014
    ..Addition of NC to the definition of metabolic syndrome should be considered and needs to be validated in future studies. ..
  7. pmc Effects of diet soda on gut hormones in youths with diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 35:959-64. 2012
    ..In this study, we examined the effect of diet soda on gut hormones in youths with diabetes...
  8. pmc Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes Technol Ther 13:457-60. 2011
    ..In this pilot study, we determined the effect of optimized insulin therapy on weight gain and frequency of hypoglycemia in patients with long-standing type 1 diabetes mellitus...
  9. pmc Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    Kristina I Rother
    Islet and Autoimmunity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 114:877-83. 2004
    ..In this review, we describe historic as well as technical details about the procedure and provide insight into clinical and basic research efforts to overcome existing hurdles for this promising therapy...
  10. pmc Interacting epidemics? Sleep curtailment, insulin resistance, and obesity
    Eliane A Lucassen
    Immunogenetics Section, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1264:110-34. 2012
    ....
  11. ncbi request reprint Assessment of islet function following islet and pancreas transplantation
    Emily C Dy
    Diabetes Branch, National Institutes of Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Diab Rep 6:316-22. 2006
    ..Development of better testing strategies, such as direct islet imaging, will significantly advance the field...
  12. pmc Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes
    Kristina I Rother
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 32:1250-5. 2009
    ..To evaluate the safety and efficacy of ingested human recombinant interferon-alpha (hrIFN-alpha) for preservation of beta-cell function in young patients with recent-onset type 1 diabetes...
  13. pmc Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 31:1403-4. 2008
    ..To determine the time course of changes in glucagon and insulin secretion in children with recently diagnosed type 1 diabetes...
  14. doi request reprint Challenging recruitment of youth with type 2 diabetes into clinical trials
    Tammy T Nguyen
    Section on Pediatric Diabetes and Metabolism, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    J Adolesc Health 54:247-54. 2014
    ..We explored whether similar strategies might be applicable to pediatric patients with type 2 diabetes...
  15. pmc Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data
    Rebecca J Brown
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Pediatr Diabetes 9:14-22. 2008
  16. pmc Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individuals
    Eliane A Lucassen
    Clinical Center, National Institutes of Health, Bethesda, MD, USA
    PLoS ONE 8:e56519. 2013
    ..5 hours per night...
  17. pmc Non-nutritive sweeteners and their role in the gastrointestinal tract
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 1645, USA
    J Clin Endocrinol Metab 97:2597-605. 2012
    ..Because consumption of non-nutritive sweeteners is common in the United States, understanding the physiological effects of these substances is of interest and importance...
  18. pmc Metabolic abnormalities and cardiovascular risk factors in children with myositis
    Kathleen Coyle
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892 1301, USA
    J Pediatr 155:882-7. 2009
    ..To characterize the metabolic abnormalities and risk factors for future cardiovascular disease in children with myositis...
  19. ncbi request reprint Resistin serum levels in type 1 diabetes pre- and post-islet transplantation
    Anath Shalev
    Transplantation and Autoimmunity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Metabolism 53:403-4. 2004
    ..Thus, our results suggest that human resistin may be involved in the pathophysiology of T1DM and thereby reveal a heretofore unappreciated aspect of human resistin biology...
  20. pmc Adrenal function in Smith-Lemli-Opitz syndrome
    Simona E Bianconi
    Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Med Genet A 155:2732-8. 2011
    ..However, we were able to show that our patients with SLOS had an adequate glucocorticoid response, and thus, in mild to moderate cases of SLOS stress steroid coverage may not be warranted...
  21. pmc Artificial sweeteners: a systematic review of metabolic effects in youth
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Pediatr Obes 5:305-12. 2010
    ....
  22. pmc Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 32:2184-6. 2009
    ..The goal of this study was to determine the effect of artificial sweeteners on glucose, insulin, and glucagon-like peptide (GLP)-1 in humans...
  23. pmc Resolution of type 2 diabetes following bariatric surgery: implications for adults and adolescents
    Radha Nandagopal
    Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Diabetes Technol Ther 12:671-7. 2010
    ..Finally, we discuss the available data on bariatric surgery in adolescent patients, including special considerations in this potentially vulnerable population...
  24. ncbi request reprint Islet transplantation: where do we stand now?
    Boaz Hirshberg
    Transplantation and Autoimmunity Branch, NIDDK NIH DHHS, Building 10, Room 11 S 219, Bethesda, MD 20892, USA
    Diabetes Metab Res Rev 19:175-8; discussion 175. 2003
    ..Two variables, as yet undefined, also need to be considered: (1) can the procedure, when done well, prevent or reverse diabetes-associated complications and (2) what are the long-term consequences of intrahepatic islets?..
  25. pmc Clinical trials in youth with type 2 diabetes
    Julie Anne L Gemmill
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Pediatr Diabetes 12:50-7. 2011
    ..We conclude that type 2 diabetes in youth is an important but difficult new field of clinical research, and we discuss the existing barriers to successful recruitment, conduct, and support of these clinical trials...
  26. pmc Minocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae
    Rebecca J Brown
    Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Rockville, Maryland, USA
    Arch Dermatol 145:63-6. 2009
    ..Long-term autoimmune sequelae of DHS have been reported, including hypothyroidism...
  27. ncbi request reprint Survival after pancreas transplantation in patients with diabetes and preserved kidney function
    Jeffrey M Venstrom
    Transplantation and Autoimmunity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    JAMA 290:2817-23. 2003
    ..Whether transplantation offers a survival advantage over conventional therapies for diabetes is unknown...
  28. pmc Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity
    April Bingham
    From Office of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland 20892 1301, USA
    Medicine (Baltimore) 87:70-86. 2008
    ..Further study is warranted to investigate the pathogenesis of acquired LD in patients with DM...
  29. ncbi request reprint Diabetes treatment--bridging the divide
    Kristina I Rother
    Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA
    N Engl J Med 356:1499-501. 2007